[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr1:37,566,653-40,170,389

Best TWAS P=3.42e-13 · Best GWAS P=1.26e-11 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	MANEAL	0.06	0.00	blup	456	0.01	2.1e-02	5.8	-5.9	3.6e-09	-0.58	0.03	0.62	FALSE
2	GTEx	Adipose Subcutaneous	INPP5B	0.44	0.33	lasso	15	0.36	3.4e-30	6.4	6.4	1.2e-10	0.67	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	RP11-109P14.10	0.28	0.21	lasso	4	0.22	6.0e-18	6.4	5.9	4.0e-09	0.58	0.02	0.98	FALSE
4	GTEx	Adipose Visceral Omentum	INPP5B	0.34	0.14	lasso	4	0.25	3.7e-13	-3.1	5.8	9.0e-09	0.65	0.10	0.90	FALSE
5	GTEx	Brain Cerebellar Hemisphere	INPP5B	0.45	0.23	lasso	4	0.29	3.0e-08	6.4	7.2	4.7e-13	0.87	0.00	0.99	FALSE
6	GTEx	Brain Cerebellum	INPP5B	0.41	0.19	lasso	9	0.28	9.2e-09	6.7	6.5	5.7e-11	0.90	0.00	0.99	FALSE
7	GTEx	Breast Mammary Tissue	INPP5B	0.32	0.20	lasso	7	0.20	2.1e-10	6.4	6.0	1.8e-09	0.66	0.02	0.98	FALSE
8	GTEx	Breast Mammary Tissue (Male)	INPP5B	0.39	0.35	lasso	4	0.30	9.6e-08	6.4	6.3	3.6e-10	0.62	0.03	0.95	FALSE
9	GTEx	Esophagus Mucosa	INPP5B	0.28	0.26	lasso	3	0.25	4.5e-17	6.4	6.6	3.2e-11	0.71	0.02	0.98	FALSE
10	GTEx	Esophagus Mucosa	RP11-109P14.10	0.14	0.12	lasso	1	0.11	1.5e-07	6.4	6.4	1.9e-10	0.64	0.02	0.98	FALSE
11	GTEx	Lung	INPP5B	0.32	0.22	lasso	6	0.26	8.4e-20	6.4	6.4	1.4e-10	0.66	0.02	0.98	FALSE
12	GTEx	Lung	RP11-109P14.10	0.15	0.03	enet	14	0.12	9.2e-10	3.5	5.6	1.9e-08	0.51	0.12	0.87	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	INPP5B	0.13	0.12	lasso	4	0.13	1.3e-07	6.8	7.1	1.3e-12	0.96	0.00	1.00	FALSE
14	GTEx	Skin Sun Exposed Lower leg	INPP5B	0.21	0.15	lasso	4	0.18	7.0e-15	6.7	7.3	3.4e-13	0.95	0.00	1.00	TRUE
15	GTEx	Spleen	INPP5B	0.77	0.51	lasso	7	0.66	2.5e-22	6.4	5.5	4.8e-08	0.54	0.04	0.96	FALSE
16	GTEx	Testis	AKIRIN1	0.41	0.15	enet	33	0.23	1.1e-10	4.7	-5.4	7.5e-08	0.02	0.01	0.98	TRUE
17	GTEx	Thyroid	INPP5B	0.14	0.06	lasso	4	0.09	1.0e-07	6.4	5.9	3.0e-09	0.66	0.04	0.96	FALSE
18	METSIM	Adipose	INPP5B	0.31	0.33	enet	21	0.35	2.4e-54	6.3	5.3	9.0e-08	0.52	0.03	0.97	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	INPP5B	0.22	0.16	lasso	3	0.20	8.0e-25	6.3	6.6	3.4e-11	0.75	0.03	0.97	FALSE
20	YFS	Blood	AKIRIN1	0.22	0.14	enet	44	0.26	3.0e-83	-4.1	-5.1	3.1e-07	0.06	0.09	0.78	FALSE
21	The Cancer Genome Atlas	Testicular Germ Cell Tumors	EPHA10	0.21	0.16	enet	7	0.07	1.9e-03	6.7	-6.7	2.1e-11	-0.97	0.00	0.99	FALSE