TWAS hub - MANEAL

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0580	0.025	0.0055	-0.002	0.010	0.00	NA	-0.002	6.5e-01	0.0210	0.290	NA	0.95000
2	METSIM	Adipose	0.0315	0.013	0.0022	0.031	0.019	0.01	NA	0.018	1.4e-05	0.0006	0.011	NA	0.00072

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Rheumatoid Arthritis	4.9	6.8	8.6	-2.9	-2.2
Alzheimer’s Disease (in father)	4.0	4.4	8.5	-0.5	2.9
Tinnitus: Yes, but not now, but have in the past	3.9	4.2	8.0	-2.8	0.7
Triglycerides	3.8	6.3	9.8	1.6	-3.1
Frequency of depressed mood in last 2 weeks	3.7	5.1	10.0	0.5	-3.2
Depression (self-reported)	3.7	4.4	8.3	0.7	-2.9
Age at first live birth	3.7	6.5	10.3	-1.6	3.2
Depression (Nagel 2018)	3.6	5.3	10.3	0.6	-3.2
Time employed in main current job	3.5	4.0	8.1	2.8	-0.1
Illness, injury, bereavement, stress in last 2 years	3.2	3.9	7.0	-0.9	2.7
Hearing aid user	3.2	3.6	5.0	1.5	-2.2
Age at First Birth	3.0	4.4	8.4	-0.6	2.9
Hypothyroidism (self reported)	3.0	6.9	10.2	-1.9	-3.2
Chronotype (morning person)	3.0	6.9	13.5	-0.7	-3.7
Had other major operations	3.0	3.7	5.5	-1.4	-2.3
Glaucoma (self-reported)	2.9	3.5	4.7	2.2	1.5
Medication: Omeprazole	2.9	3.4	6.0	-2.4	-0.9
Diastolic blood pressure, automated reading	2.9	9.1	18.1	-0.3	-4.3
Heel T-Score	2.8	22.2	44.1	-0.5	6.6
Medication: Levothyroxine sodium	2.8	4.8	4.9	-2.2	-2.1
Migraine (self-reported)	2.8	3.5	6.8	-0.3	2.6
Forced expiratory volume in 1-second (FEV1), predicted	2.8	5.9	8.9	1.7	-3.0
Schizophrenia (2018)	2.7	5.6	7.2	2.0	-2.7
Medication: Paracetamol	2.7	4.4	8.6	2.9	-0.4
Long-standing illness, disability or infirmity	2.7	4.1	5.7	-1.6	-2.4
Sitting height	2.6	18.7	35.3	1.4	-5.9
Medication: Bendroflumethiazide	2.5	3.8	5.0	1.6	2.2
Major Depression (MDD)	2.4	2.9	5.0	-0.9	-2.2
Blood Eosinophil Count	2.4	18.8	34.8	-5.9	1.7
Supplements: Zinc	2.4	2.6	4.5	2.1	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	2.4	7.7	13.9	-1.2	-3.7
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.6	4.1	-1.8	-2.0
Medication: Amlodipine	2.4	3.3	6.5	-0.4	2.5
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.1	4.2	-2.0	-1.4
Medication: Ibuprofen	2.4	2.9	5.1	0.7	-2.3
Allergy or Eczema	2.3	6.0	8.4	-2.9	-1.9
Height	2.2	42.5	79.6	2.3	-8.9
Prospective memory result	2.2	2.7	5.4	-0.1	-2.3
Peak expiratory flow (PEF)	2.2	5.2	10.1	-0.5	-3.2
Hypothyroidism/myxoedema (self-reported)	2.2	4.2	7.2	-1.1	-2.7
Forced vital capacity (FVC), Best measure	2.2	8.2	15.8	-0.7	-4.0
Illnesses of father: Heart disease	2.2	3.1	4.3	-1.3	2.1
Medication: Gliclazide	2.2	2.5	3.6	-1.9	1.2
Allergy	2.1	4.8	8.8	3.0	0.9
Number of live births	2.1	3.0	6.0	0.2	-2.4
Leg fat-free mass (right)	2.1	11.1	22.2	-0.1	-4.7
Medication: Co-codamol	2.0	2.3	2.6	-1.4	-1.6
Hair/balding pattern: Pattern 4	2.0	4.8	5.2	-2.3	2.1
Number of full brothers	2.0	2.5	3.8	1.1	-1.9
Leg predicted mass (right)	2.0	10.9	21.7	-0.0	-4.7
Financial situation satisfaction	2.0	2.4	4.8	0.4	-2.2
Eye problems/disorders: Glaucoma	2.0	2.4	3.1	1.8	1.3
Medication: Paracetamol	2.0	3.1	5.1	2.2	-1.0
Alcohol drinker status: Previous	2.0	2.3	4.5	-0.1	-2.1
Leg fat-free mass (left)	1.9	10.3	20.5	0.2	-4.5
Leg predicted mass (left)	1.9	10.2	20.2	0.3	-4.5
Diabetes (self-reported)	1.9	3.0	5.9	0.4	-2.4
Standing height	1.9	18.8	36.0	1.2	-6.0
Birth weight of first child	1.9	3.5	5.1	-1.4	2.3
Ever had hysterectomy (womb removed)	1.8	2.1	2.5	1.3	-1.6
Systolic blood pressure, automated reading	1.8	5.2	9.4	-1.0	3.1
Relative age voice broke	1.8	2.8	5.5	-0.3	2.3
Hearing difficulty/problems with background noise	1.8	2.9	4.7	-1.0	-2.2
Weight	1.8	9.1	17.8	0.6	-4.2
Hip circumference	1.8	7.8	15.4	0.5	-3.9
Mouth/teeth dental problems: Dentures	1.8	3.0	5.7	-0.5	-2.4
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	2.9	1.7	-1.3
Eye problems/disorders: Cataract	1.8	2.1	4.2	-0.3	-2.0
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	4.0	-2.0	-0.6
Forced expiratory volume in 1-second (FEV1)	1.7	5.9	10.7	-1.0	-3.3
Illnesses of siblings: Diabetes	1.7	2.1	3.5	-0.8	-1.9
Commuting to job workplace: Public transport	1.7	2.0	4.0	-0.0	2.0
Medication: Atorvastatin	1.7	2.1	3.2	-1.0	1.8
Basal metabolic rate	1.7	9.6	19.0	0.5	-4.4
Number of operations (self-reported)	1.7	2.5	5.0	0.1	-2.2
Qualifications: CSEs or equivalent	1.6	2.1	2.6	-1.3	-1.6
Hayfever, allergic rhinitis or eczema	1.6	3.5	4.8	-2.2	-1.5
Headache pain in last month	1.6	2.7	5.0	2.2	0.7
Whole body fat-free mass	1.6	9.3	18.1	0.7	-4.3
Whole body water mass	1.6	8.9	17.3	0.7	-4.2
Schizophrenia (2014)	1.5	3.2	4.2	1.5	-2.1
Systolic Blood Pressure	1.5	7.6	15.1	0.2	3.9
Severe depression (siblings)	1.5	1.6	2.9	-0.6	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	4.0	0.1	-2.0
Alcohol intake versus 10 years previously	1.5	2.2	3.4	-1.0	-1.8
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.8	3.5	0.3	1.9
Family relationship satisfaction	1.5	1.8	1.9	-1.3	-1.4
Handedness (chirality/laterality): Left-handed	1.5	1.7	2.6	1.0	1.6
Hearing difficulty/problems: Yes	1.4	2.1	4.3	-0.0	-2.1
Relative age of first facial hair	1.4	2.9	4.0	1.4	2.0
Diabetes (father)	1.4	1.8	2.7	1.6	0.9
Trunk fat mass	1.4	6.0	11.7	0.4	-3.4
Arm fat-free mass (right)	1.4	7.3	14.2	0.7	-3.8
Age at last live birth	1.4	2.1	2.9	-1.7	1.1
Arm fat-free mass (left)	1.4	6.9	13.3	0.7	-3.6
Age started oral contraceptive pill	1.4	1.8	3.0	1.7	0.8
Bipolar Disorder or Schizophrenia	1.3	3.1	5.1	1.0	-2.3
Lupus	1.3	2.0	3.5	-0.8	-1.9
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	3.1	-1.8	-0.3
Trunk fat-free mass	1.3	7.6	14.1	1.0	-3.8
Father’s age at death	1.3	1.8	3.5	-0.2	-1.9
Trunk predicted mass	1.3	7.4	13.6	1.1	-3.7
Exposure to tobacco smoke outside home	1.3	1.8	3.4	-1.8	-0.4
Whole body fat mass	1.3	5.5	10.9	0.5	-3.3
Alcohol intake frequency.	1.3	3.0	3.3	1.8	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.8	4.0	-1.3	-2.0
Commuting to job workplace: Cycle	1.3	1.6	3.1	-1.8	-0.3
Arm predicted mass (left)	1.3	6.5	12.7	0.5	-3.6
Ulcerative Colitis (UC)	1.2	2.3	2.8	1.4	1.7
Prostate Cancer	1.2	1.7	3.1	0.6	1.8
Average weekly spirits intake	1.2	1.5	1.6	1.2	-1.3
Nervous feelings	1.2	2.3	2.3	1.5	1.5
Had menopause	1.2	1.5	2.9	0.4	1.7
Forced vital capacity (FVC)	1.2	4.7	9.2	-0.5	-3.0
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	5.3	0.1	2.3
Arm predicted mass (right)	1.2	6.0	11.3	0.8	-3.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	2.2	-0.7	1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	2.6	-0.2	-1.6
Average weekly champagne plus white wine intake	1.2	1.6	3.2	-0.3	1.8
Guilty feelings	1.2	1.7	1.8	1.4	-1.3
Alcohol drinker status: Never	1.2	1.4	1.7	1.1	1.3
Depressed Affect (Nagel 2018)	1.1	2.2	4.5	-0.0	-2.1
Coronary Artery Disease (CAD)	1.1	1.3	2.6	0.2	1.6
Lung FEV1/FVC ratio	1.1	5.7	8.7	-1.7	-3.0
Sensitivity / hurt feelings	1.1	1.9	3.7	-0.2	-1.9
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	2.0	1.4	-0.6
Arm fat mass (right)	1.1	4.4	8.7	0.1	-3.0
Wheeze or whistling in the chest in last year	1.1	2.0	3.9	-2.0	0.3
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	2.6	-1.6	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	1.7	-1.3	0.9
Average weekly beer plus cider intake	1.1	1.5	1.6	-1.2	1.3
Alzheimer’s Disease (in mother)	1.0	1.1	2.0	0.4	-1.4
Medication for hormone replacement therapy	1.0	1.1	1.5	1.2	-0.9
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	2.2	1.5	-0.5
Hair/balding pattern: Pattern 3	1.0	1.4	1.7	-1.1	1.3
Asthma	1.0	1.9	3.7	-1.9	-0.4
Exposure to tobacco smoke at home	1.0	1.1	2.2	-1.5	-0.2
Comparative height size at age 10	1.0	5.3	10.3	0.6	-3.2
Osteoarthritis (self-reported)	1.0	1.3	1.6	-1.0	-1.3
Arm fat mass (left)	1.0	4.1	8.1	0.3	-2.8
Ever had prostate specific antigen (PSA) test	1.0	1.1	1.9	0.6	-1.4
Supplements: Calcium	1.0	1.1	2.1	1.4	0.2
Heart attack/myocardial infarction (self-reported)	1.0	1.3	2.3	-0.5	1.5
Primary Biliary Cirrhosis	0.9	1.3	2.7	0.1	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	4.2	0.2	2.0
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.2	1.5	-0.1
Waist circumference	0.9	3.4	6.7	-0.3	-2.6
Heart attack	0.9	1.1	1.8	-0.6	1.3
Medication: Lansoprazole	0.9	1.1	1.2	1.0	1.1
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	2.0	-0.5	1.4
Health satisfaction	0.9	1.2	1.2	-1.0	-1.1
Qualifications: College or University degree	0.9	2.9	4.9	0.9	2.2
Medication: Allopurinol	0.9	1.2	1.5	0.9	-1.2
Diabetes diagnosed by doctor	0.9	1.4	2.9	0.2	-1.7
Cholesterol lowering medication	0.9	1.4	2.5	-1.6	0.5
Neuroticism (Nagel 2018)	0.8	1.9	3.6	0.5	-1.9
Schizophrenia vs Biploar Disorder	0.8	1.0	1.9	1.4	-0.4
Ovarian Cancer	0.8	1.1	2.0	-0.5	1.4
HDL Cholesterol	0.8	1.4	2.3	-0.7	1.5
Trunk fat percentage	0.8	3.3	6.6	0.2	-2.6
Chronic bronchitis/emphysema (father)	0.8	1.0	1.2	1.1	-0.9
Chronic bronchitis/emphysema (mother)	0.8	0.9	1.3	1.1	-0.8
Shortness of breath walking on level ground	0.8	0.9	1.3	0.7	-1.1
Leg pain on walking	0.8	1.0	1.7	-1.3	-0.5
Loneliness, isolation	0.8	1.1	1.4	1.2	-0.9
Friendships satisfaction	0.8	1.0	1.5	-1.2	0.7
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	2.2	-1.5	0.6
Asthma (self-reported)	0.8	1.5	2.6	-1.6	-0.7
Leg fat mass (left)	0.8	3.2	6.1	0.5	-2.5
Ulcerative Colitis	0.7	1.0	2.0	-0.1	1.4
Medication: Metformin	0.7	1.1	2.1	-0.2	-1.4
Diabetes (mother)	0.7	0.9	1.7	-0.1	-1.3
Townsend deprivation index at recruitment	0.7	1.0	2.0	0.3	-1.4
Arm fat percentage (right)	0.7	2.8	5.6	0.0	-2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.7	-0.1	1.3
Leg fat mass (right)	0.7	2.8	5.2	0.6	-2.3
Medication: Aspirin	0.7	0.9	1.5	-0.5	1.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.3	-0.5	-1.1
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.7	-0.3	1.3
Unable to work because of sickness or disability	0.7	0.9	1.0	-1.0	-0.9
Irritable Bowel Disease (IBD)	0.6	1.3	1.5	1.2	1.1
Mean Putamen Volume	0.6	0.7	1.1	1.0	0.5
Neuroticism (2016)	0.6	0.9	1.4	1.2	-0.7
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.1	-0.6	-1.0
Lung FVC	0.6	2.9	3.5	-1.5	-1.9
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.2	-0.2	-1.1
Medication: Atenolol	0.6	0.7	1.5	0.0	1.2
Hair/balding pattern: Pattern 2	0.6	0.8	1.6	1.3	-0.0
Qualifications: A levels/AS levels or equivalent	0.6	1.3	1.8	0.9	1.3
Medication: Cholesterol lowering	0.6	1.0	1.8	-0.4	1.4
Loud music exposure frequency	0.6	0.7	0.7	-0.8	-0.8
Medication for cholesterol, blood pressure or diabetes	0.6	1.1	2.0	0.3	-1.4
Body fat percentage	0.6	2.3	4.4	0.3	-2.1
Medication: Blood pressure	0.6	1.1	2.1	-0.5	1.4
Heart disease (mother)	0.6	0.7	1.3	1.1	-0.4
Overall health rating	0.6	1.2	1.3	-1.2	-1.1
Supplements: Vitamin C	0.6	0.7	1.3	0.2	1.2
Knee pain experienced in last month	0.6	0.9	1.2	-1.1	-0.8
Smoking status: Previous	0.6	0.9	0.9	-0.9	-0.9
Arm fat percentage (left)	0.6	2.3	4.5	0.2	-2.1
Blood Red Count	0.5	4.9	8.6	-1.1	-2.9
Type 2 Diabetes (T2D) (2018)	0.5	0.9	1.7	0.2	-1.3
Hand grip strength (left)	0.5	1.4	2.8	1.7	0.1
Ever used hormone-replacement therapy (HRT)	0.5	0.7	0.9	0.7	-0.9
Impedance of leg (right)	0.5	2.5	4.8	0.6	2.2
High blood pressure (mother)	0.5	0.7	1.0	-1.0	-0.7
Past tobacco smoking	0.5	0.9	1.6	1.3	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.5	-0.4	-1.2
Happiness	0.5	0.6	1.1	-1.1	0.0
Breastfed as a baby	0.5	0.6	0.9	-0.6	0.9
Worry too long after embarrassment	0.5	0.9	1.7	1.3	-0.3
Medication: Seretide 50 evohaler	0.5	0.5	1.1	-0.0	-1.0
Pulse rate, automated reading	0.5	1.5	3.1	1.8	-0.0
Had major operations	0.5	0.6	1.0	1.0	-0.5
Commuting to job workplace: Car/motor vehicle	0.5	0.5	1.0	0.2	-1.0
Average weekly red wine intake	0.5	0.8	0.8	0.9	-0.9
Illnesses of father: None of the above (group 1)	0.5	0.6	0.7	-0.8	-0.8
Basal cell carcinoma (self-reported)	0.5	0.5	0.6	0.7	-0.8
HbA1C	0.4	0.4	0.5	0.7	-0.6
Blood White Count	0.4	3.3	5.3	-1.1	2.3
Respiratory disease	0.4	0.8	0.9	-1.0	-0.8
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.0	-0.2	-1.0
Maternal smoking around birth	0.4	0.5	1.0	0.3	-1.0
Serious illness, injury or assault to yourself	0.4	0.5	0.7	-0.6	-0.9
Impedance of leg (left)	0.4	1.9	3.5	0.5	1.9
Lung cancer (father)	0.4	0.5	0.8	0.4	-0.9
Blood clot in the leg (DVT)	0.4	0.5	0.8	-0.5	0.9
Number of children fathered	0.4	0.5	0.9	0.1	1.0
Emphysema/chronic bronchitis	0.4	0.5	0.9	0.9	-0.2
Medication for pain relief, constipation, heartburn	0.4	0.6	1.2	-1.1	-0.1
Neck or shoulder pain in last month	0.4	0.5	1.0	0.1	-1.0
Ever had bowel cancer screening	0.4	0.5	0.9	-0.9	-0.3
Number of self-reported non-cancer illnesses	0.4	0.8	1.5	-0.3	-1.2
Miserableness	0.4	0.7	1.1	-0.5	-1.0
Irritability	0.4	0.7	1.3	1.1	0.3
Fractured/broken bones in last 5 years	0.4	0.5	1.1	0.0	-1.0
Ever depressed for a whole week	0.4	0.5	0.6	-0.8	0.6
Bipolar Disorder (2018)	0.3	0.4	0.7	-0.8	-0.3
Intelligence (Savage-Jansen 2018)	0.3	1.0	1.2	1.1	0.9
Alzheimer’s Disease (including proxy)	0.3	0.4	0.7	-0.3	0.8
Breast Cancer	0.3	0.8	1.5	1.2	0.3
Fasting Glucose	0.3	0.4	0.7	-0.4	-0.8
BMI	0.3	2.0	2.0	1.4	-1.4
Supplements: Glucosamine	0.3	0.3	0.6	0.2	0.8
Body mass index (BMI)	0.3	1.1	2.2	0.1	-1.5
Number of incorrect matches in round	0.3	0.5	0.9	-0.1	-1.0
Pain all over the body in last month	0.3	0.3	0.4	0.5	-0.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.9	-0.1	-0.9
Worrier / anxious feelings	0.3	0.5	0.5	-0.7	0.7
Falls in the last year	0.3	0.4	0.7	-0.8	-0.5
Eye problems/disorders: None of the above	0.3	0.4	0.7	-0.2	0.8
Medication: Aspirin	0.3	0.4	0.5	-0.6	0.7
Osteoporosis (self-reported)	0.3	0.4	0.7	0.8	-0.2
Medication: Blood pressure	0.3	0.6	0.7	0.8	0.7
Illnesses of father: High blood pressure	0.3	0.3	0.6	0.2	0.8
Ever smoked	0.3	0.6	0.6	-0.7	-0.8
Myopia	0.3	0.4	0.6	-0.8	-0.4
LDL Cholesterol	0.2	0.4	0.6	0.4	-0.8
Waist Hip Ratio (WHR)	0.2	0.7	1.5	-1.2	0.1
Vitamin and mineral supplements	0.2	0.2	0.3	0.6	0.4
Average weekly fortified wine intake	0.2	0.2	0.3	-0.3	-0.6
Fed-up feelings	0.2	0.3	0.5	0.3	-0.7
Taking other prescription medications	0.2	0.4	0.6	0.4	-0.8
Qualifications: None of the above	0.2	0.4	0.6	0.5	-0.8
Financial difficulties in last 2 years	0.2	0.2	0.4	-0.2	-0.7
Fluid intelligence score	0.2	0.4	0.7	0.3	0.8
Illnesses of siblings	0.2	0.3	0.6	0.8	0.1
Gout (self-reported)	0.2	0.3	0.4	0.6	-0.4
Comparative body size at age 10	0.2	0.7	1.3	1.2	0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.3	0.6	-0.3
Number of full sisters	0.2	0.2	0.4	-0.6	0.0
Mood swings	0.2	0.3	0.4	0.4	-0.7
Mineral and other dietary supplements	0.2	0.3	0.4	-0.5	-0.6
Breast cancer (self-reported)	0.2	0.3	0.5	-0.0	0.7
Wears glasses or contact lenses	0.2	0.2	0.2	-0.5	0.5
Risk taking	0.2	0.3	0.5	-0.2	0.7
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.4	-0.3	0.6
Heart disease (siblings)	0.2	0.2	0.3	0.4	0.6
Worry (Nagel 2018)	0.1	0.2	0.3	-0.6	-0.0
Crohns Disease (2017)	0.1	0.2	0.3	0.6	-0.2
Body Mass Index (BMI) (2010)	0.1	0.1	0.2	-0.3	0.4
Crohns Disease (2012)	0.1	0.1	0.2	-0.5	0.1
Blood Platelet Count	0.1	0.8	1.5	-1.2	0.0
Cardiovascular Disease	0.1	0.5	0.9	1.0	-0.1
Neuroticism	0.1	0.2	0.4	0.2	-0.6
Hair Pigment	0.1	1.6	3.0	0.6	-1.7
Angina	0.1	0.2	0.3	-0.1	0.6
Pack years adult smoking proportion	0.1	0.1	0.2	0.5	0.2
Hand grip strength (right)	0.1	0.4	0.4	0.6	-0.6
Current tobacco smoking	0.1	0.2	0.4	0.0	0.6
Multivitamins +/- minerals	0.1	0.2	0.3	-0.6	-0.2
Stomach or abdominal pain in last month	0.1	0.1	0.1	0.2	0.3
Mouth/teeth dental problems	0.1	0.2	0.4	-0.0	0.6
Medication: Simvastatin	0.1	0.1	0.2	0.0	0.4
Impedance of arm (right)	0.1	0.3	0.6	0.1	-0.8
Pulse rate	0.1	0.2	0.2	-0.3	0.5
Pulse wave Arterial Stiffness index	0.1	0.1	0.1	0.3	-0.2
Length of working week for main job	0.1	0.1	0.3	-0.0	-0.5
Tense / ‘highly strung’	0.1	0.1	0.3	0.1	-0.5
Pulse wave reflection index	0.1	0.1	0.2	0.2	-0.4
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.2	0.3	-0.5
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.2	-0.3	-0.4
Birth weight	0.1	0.3	0.5	0.2	-0.7
High blood pressure (siblings)	0.1	0.2	0.4	-0.2	-0.6
Leg fat percentage (right)	0.1	0.4	0.6	0.8	-0.5
Angina (self-reported)	0.1	0.1	0.2	0.0	0.4
Mean time to correctly identify matches	0.1	0.2	0.2	-0.4	0.4
Suffer from ‘nerves’	0.1	0.1	0.2	-0.4	-0.0
Hypertension (Self-reported)	0.1	0.3	0.5	0.7	-0.3
Qualifications: nursing, teaching	0.1	0.1	0.1	-0.2	0.4
Medication for cholesterol	0.1	0.1	0.1	-0.4	-0.1
Back pain experienced in last month	0.1	0.2	0.4	-0.1	-0.6
Smoking status: Current	0.1	0.2	0.3	-0.2	0.6
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.2	0.5	-0.1
High cholesterol (Self-reported)	0.1	0.2	0.3	-0.5	0.3
Medication: Lisinopril	0.1	0.2	0.3	0.6	-0.0
Leg fat percentage (left)	0.1	0.5	0.5	0.7	-0.7
Pack years of smoking	0.1	0.1	0.2	0.4	-0.0
Reaction Time	0.0	0.1	0.2	0.1	-0.4
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.2	-0.1	0.5
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Smoking Status	0.0	0.1	0.1	-0.3	-0.2
Tanning	0.0	0.2	0.2	-0.4	-0.5
Number of treatments/medications taken	0.0	0.0	0.0	0.0	0.0
Age when periods started (menarche)	0.0	0.1	0.2	-0.2	0.4
High blood pressure	0.0	0.1	0.2	0.4	-0.0
Alcohol usually taken with meals	0.0	0.0	0.1	-0.3	-0.1
Medication: Ramipril	0.0	0.0	0.1	-0.0	0.3
Neuroticism score	0.0	0.0	0.1	-0.3	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.0	-0.1	-0.1
Noisy workplace	0.0	0.0	0.0	-0.1	-0.1
Illnesses of mother	0.0	0.0	0.0	-0.1	-0.2
Impedance of arm (left)	0.0	0.2	0.3	-0.0	-0.6
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.1	-0.2	-0.2
Pulse wave peak to peak time	0.0	0.0	0.1	-0.2	-0.2
Chest pain or discomfort	0.0	0.1	0.1	-0.3	0.2
Commuting to job workplace: Walk	0.0	0.0	0.1	-0.0	0.3
Ever taken oral contraceptive pill	0.0	0.0	0.1	0.3	0.1
Mother’s age at death	0.0	0.0	0.0	-0.1	-0.2
Vascular/heart problems diagnosed by doctor	0.0	0.0	0.1	-0.2	0.1
Pain experienced in last month	0.0	0.0	0.0	-0.2	-0.2
Impedance of whole body	0.0	0.1	0.3	0.2	0.5

Hub : Genes

MANEAL

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Trait associations