Best TWAS P=1.17e-60 · Best GWAS P=5.01e-79 conditioned to 3.14e-17
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | ADRB2 | 0.09 | 0.05 | bslmm | 455 | 0.05 | 2.4e-15 | -18.6 | -16.4 | 1.2e-60 | 0.87 | 0.02 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | ADRB2 | 0.08 | 0.00 | blup | 55 | 0.01 | 7.7e-02 | 8.9 | 11.4 | 3.6e-30 | -0.58 | 0.01 | 0.39 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | FBXO38 | 0.11 | 0.02 | blup | 52 | 0.04 | 8.2e-06 | -4.3 | 5.2 | 1.8e-07 | 0.03 | 0.02 | 0.90 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | ADRB2 | 0.08 | 0.05 | lasso | 4 | 0.04 | 5.8e-06 | 4.4 | 6.6 | 4.3e-11 | -0.34 | 0.81 | 0.16 | FALSE |