[Hub]/) : Traits : Blood Eosinophil Count :

chr7:814,788-3,778,937

Best TWAS P=6.39e-23 · Best GWAS P=1.81e-21 conditioned to 0.517

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue (Female) GNA12 0.10 -0.01 enet 16 0.00 4.5e-01 -3.1 5.3 1.2e-07 0.18 0.06 0.06 TRUE
2 GTEx Colon Sigmoid INTS1 0.39 0.25 enet 18 0.26 8.6e-10 4.8 -5.6 1.9e-08 0.05 0.01 0.98 FALSE
3 GTEx Esophagus Mucosa INTS1 0.34 0.27 enet 10 0.33 1.4e-22 4.9 -5.1 3.0e-07 0.03 0.01 0.98 FALSE
4 GTEx Pancreas INTS1 0.30 0.22 enet 8 0.20 6.6e-09 4.8 -5.2 1.9e-07 0.03 0.01 0.98 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic TTYH3 0.22 0.00 lasso 5 0.00 6.4e-01 9.5 9.6 1.3e-21 0.81 0.01 0.85 TRUE
6 GTEx Skin Not Sun Exposed Suprapubic INTS1 0.36 0.25 lasso 7 0.27 5.4e-15 4.8 -5.2 2.1e-07 0.04 0.01 0.98 FALSE
7 GTEx Small Intestine Terminal Ileum GNA12 0.34 0.20 lasso 5 0.16 2.4e-04 3.4 5.7 1.4e-08 0.16 0.23 0.24 TRUE
8 GTEx Whole Blood INTS1 0.19 0.07 lasso 9 0.10 2.1e-09 4.8 -5.2 2.6e-07 0.04 0.01 0.98 FALSE
9 YFS Blood CARD11 0.07 0.06 lasso 6 0.06 6.7e-18 9.4 9.9 6.4e-23 0.53 0.01 0.99 TRUE
10 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma INTS1 0.28 0.21 lasso 5 0.20 1.8e-08 4.9 -5.2 2.0e-07 0.04 0.01 0.98 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma INTS1 0.18 0.18 enet 8 0.18 1.3e-18 5.0 -5.7 1.6e-08 0.04 0.01 0.99 TRUE