Best TWAS P=3.58e-18 · Best GWAS P=5.85e-33 conditioned to 1.85e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | AK3P3 | 0.27 | 0.15 | enet | 23 | 0.14 | 8.4e-05 | 0.32 | -5.7 | 1.2e-08 | -0.31 | 0.30 | 0.17 | TRUE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | FAM126A | 0.35 | 0.00 | enet | 41 | 0.01 | 1.7e-01 | -2.03 | -5.5 | 4.1e-08 | -0.15 | 0.08 | 0.06 | FALSE |
| 3 | GTEx | Esophagus Muscularis | FAM126A | 0.11 | 0.00 | lasso | 8 | 0.01 | 5.9e-02 | 4.35 | -8.7 | 3.6e-18 | -0.42 | 0.04 | 0.73 | TRUE |