Best TWAS P=3.81e-08 · Best GWAS P=2.95e-09 conditioned to 2.09e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | LPL | 0.09 | 0.00 | bslmm | 668 | 0.02 | 1.0e-03 | 5.3 | -5.2 | 2.0e-07 | -0.39 | 0.08 | 0.71 | FALSE |
2 | YFS | Blood | LPL | 0.06 | 0.07 | lasso | 2 | 0.06 | 6.5e-20 | 5.6 | 5.5 | 3.8e-08 | 0.36 | 0.02 | 0.98 | TRUE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LPL | 0.09 | 0.12 | lasso | 4 | 0.11 | 3.5e-12 | 5.2 | -5.2 | 2.5e-07 | -0.58 | 0.07 | 0.93 | FALSE |