[Hub]/) : Traits : Blood Eosinophil Count :

chr8:47,421,087-49,584,958

Best TWAS P=4.34e-16 · Best GWAS P=1.49e-15 conditioned to 0.0163

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KIAA0146 0.06 0.07 lasso 5 0.07 3.0e-09 7.2 -6.7 2.3e-11 -0.51 0.25 0.75 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC100287846 0.02 0.00 blup 149 0.01 2.9e-02 4.9 -5.8 6.6e-09 -0.48 0.15 0.25 FALSE
3 CommonMind Brain Pre-frontal Cortex MCM4 0.29 0.10 enet 36 0.17 1.7e-20 4.9 -7.8 6.3e-15 -0.64 0.01 0.99 FALSE
4 GTEx Adipose Visceral Omentum RP11-697N18.3 0.10 0.12 enet 11 0.11 3.1e-06 6.3 7.4 1.5e-13 0.67 0.09 0.88 FALSE
5 GTEx Brain Frontal Cortex BA9 SPIDR 0.19 0.12 lasso 18 0.14 1.9e-04 7.3 -8.1 4.3e-16 -0.62 0.06 0.89 TRUE
6 GTEx Testis MCM4 0.11 0.00 enet 31 0.01 1.1e-01 5.0 -6.6 3.4e-11 -0.59 0.01 0.93 FALSE
7 METSIM Adipose MCM4 0.14 0.00 enet 33 0.06 1.6e-09 4.8 -6.2 5.4e-10 -0.60 0.06 0.71 FALSE
8 ROSMAP Brain Pre-frontal Cortex MCM4 0.20 0.02 bslmm 184 0.08 2.8e-10 5.0 -7.5 5.6e-14 -0.68 0.01 0.99 TRUE
9 ROSMAP Brain Pre-frontal Cortex SPIDR 0.08 0.07 enet 14 0.07 1.3e-09 6.6 -6.8 9.6e-12 -0.59 0.26 0.74 FALSE
10 ROSMAP Brain Pre-frontal Cortex RP11-1134I14.8 0.06 0.04 blup 125 0.05 1.9e-07 5.7 -6.5 9.0e-11 -0.49 0.12 0.88 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma MCM4 0.05 0.04 lasso 2 0.04 5.1e-05 5.8 -5.7 1.1e-08 -0.33 0.00 0.98 FALSE
12 The Cancer Genome Atlas Liver Hepatocellular Carcinoma MCM4 0.19 0.10 enet 1 0.10 3.1e-05 5.8 -5.8 5.7e-09 -0.42 0.00 0.99 FALSE