Best TWAS P=8.45e-11 · Best GWAS P=4.03e-10 conditioned to 0.0812
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Colon Adenocarcinoma | PTK2B | 0.07 | 0.07 | lasso | 3 | 0.06 | 0.00023 | -5.5 | 5.9 | 2.7e-09 | -0.69 | 0.10 | 0.70 | FALSE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | PTK2B | 0.04 | 0.00 | blup | 143 | 0.02 | 0.00987 | -6.2 | 6.5 | 8.5e-11 | -0.80 | 0.01 | 0.65 | TRUE |