[Hub]/) : Traits : Blood Eosinophil Count :

chr9:126,321,003-127,872,298

Best TWAS P=7.42e-11 · Best GWAS P=3.53e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PSMB7 0.08 0.04 lasso 6 0.04 3.4e-04 6.1 -6.2 7.5e-10 -0.92 0.05 0.94 FALSE
2 GTEx Artery Aorta PSMB7 0.15 0.03 enet 16 0.05 1.4e-03 -4.1 -5.2 2.1e-07 -0.63 0.08 0.63 FALSE
3 GTEx Artery Tibial PSMB7 0.07 0.04 enet 7 0.03 4.1e-03 6.1 -6.2 7.1e-10 -0.88 0.02 0.96 FALSE
4 GTEx Colon Sigmoid PSMB7 0.15 0.10 lasso 3 0.09 3.3e-04 6.6 -6.5 7.4e-11 -0.99 0.01 0.97 TRUE
5 GTEx Thyroid NEK6 0.20 0.21 lasso 4 0.20 1.3e-15 6.2 -6.0 1.9e-09 -0.92 0.03 0.97 FALSE
6 GTEx Thyroid PSMB7 0.06 0.04 lasso 2 0.06 4.1e-05 5.2 -6.1 9.0e-10 -0.90 0.02 0.96 FALSE
7 The Cancer Genome Atlas Pancreatic Adenocarcinoma NEK6 0.14 0.02 blup 87 0.05 2.8e-03 -3.3 5.6 1.9e-08 0.73 0.02 0.53 FALSE
8 The Cancer Genome Atlas Prostate Adenocarcinoma PSMB7 0.03 0.04 lasso 4 0.04 1.2e-04 5.9 -5.8 7.1e-09 -0.88 0.08 0.84 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma PSMB7 0.06 0.06 lasso 4 0.04 3.7e-05 5.3 -5.3 1.4e-07 -0.85 0.62 0.38 FALSE