[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr1:100,643,910-102,246,949

Best TWAS P=2.01e-32 · Best GWAS P=8.26e-37 conditioned to 1.2e-12

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere RP11-421L21.3 0.19 0.31 lasso 4 0.28 5.4e-08 -8.8 -8.8 8.6e-19 0.56 0.50 0.28 FALSE
2 GTEx Brain Cerebellum RP11-421L21.3 0.37 0.44 lasso 3 0.43 3.9e-14 -8.8 -8.8 1.3e-18 0.56 1.00 0.00 FALSE
3 GTEx Brain Cortex RP11-421L21.3 0.34 0.37 lasso 6 0.35 1.4e-10 -8.8 -8.8 9.6e-19 0.57 0.95 0.04 FALSE
4 GTEx Brain Frontal Cortex BA9 RP11-421L21.3 0.39 0.39 lasso 5 0.35 3.0e-10 -10.0 -10.0 1.5e-23 0.59 0.98 0.01 FALSE
5 GTEx Brain Hippocampus RP11-421L21.3 0.23 0.11 lasso 6 0.04 3.5e-02 -8.6 -10.3 4.7e-25 0.74 0.10 0.32 FALSE
6 GTEx Cells Transformed fibroblasts SLC30A7 0.09 0.04 lasso 9 0.05 1.0e-04 -10.0 6.7 1.6e-11 -0.37 0.83 0.02 FALSE
7 GTEx Cells Transformed fibroblasts RP4-549L20.3 0.11 0.08 lasso 2 0.07 9.6e-06 8.4 -8.1 3.9e-16 0.30 0.55 0.02 FALSE
8 GTEx Esophagus Mucosa RP11-421L21.3 0.14 0.08 lasso 6 0.07 1.9e-05 -8.8 -10.4 2.2e-25 0.61 0.61 0.22 FALSE
9 GTEx Nerve Tibial RP11-421L21.3 0.07 0.09 lasso 1 0.09 1.1e-06 -10.0 -10.0 2.4e-23 0.59 0.77 0.08 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic RP11-421L21.3 0.12 0.09 lasso 3 0.04 3.2e-03 -8.6 -8.8 1.1e-18 0.57 0.66 0.20 FALSE
11 GTEx Spleen RP11-421L21.3 0.36 0.28 lasso 5 0.34 1.6e-09 -10.0 -7.9 2.0e-15 0.51 0.62 0.09 FALSE
12 GTEx Thyroid RP11-421L21.3 0.11 0.15 enet 15 0.15 1.6e-11 -8.8 -8.4 4.8e-17 0.55 1.00 0.00 FALSE
13 ROSMAP Brain Pre-frontal Cortex EXTL2 0.07 0.02 blup 424 0.03 6.1e-05 8.2 11.9 2.0e-32 -0.58 0.87 0.10 TRUE
14 ROSMAP Brain Pre-frontal Cortex RP11-421L21.3 0.15 0.22 lasso 15 0.21 9.6e-27 -8.8 -8.1 7.8e-16 0.55 1.00 0.00 FALSE