[Hub]/) : Traits : Blood Eosinophil Count :

chr10:26,033,058-27,549,961

Best TWAS P=1.42e-61 · Best GWAS P=3.03e-56 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial APBB1IP 0.19 0.16 enet 5 0.17 2.6e-13 15.4 15.6 7.7e-55 0.99 0.01 0.99 FALSE
2 GTEx Cells Transformed fibroblasts APBB1IP 0.30 0.20 lasso 10 0.20 4.9e-15 15.6 16.6 1.4e-61 0.98 0.00 1.00 TRUE
3 GTEx Esophagus Muscularis APBB1IP 0.12 0.09 lasso 3 0.08 1.6e-05 15.8 15.7 1.1e-55 0.99 0.00 1.00 FALSE
4 GTEx Liver APBB1IP 0.26 0.11 lasso 7 0.06 1.1e-02 9.6 11.9 1.1e-32 0.89 0.01 0.96 TRUE
5 GTEx Pituitary APBB1IP 0.53 0.37 lasso 8 0.38 1.6e-10 15.5 14.5 7.0e-48 0.97 0.02 0.98 FALSE
6 GTEx Stomach APBB1IP 0.31 0.05 lasso 4 0.05 2.9e-03 14.7 14.2 1.6e-45 0.88 0.05 0.87 FALSE
7 METSIM Adipose APBB1IP 0.07 0.04 lasso 6 0.03 8.2e-06 15.8 15.3 5.5e-53 0.99 0.00 1.00 FALSE
8 ROSMAP Brain Pre-frontal Cortex APBB1IP 0.07 0.04 blup 485 0.03 1.2e-04 14.7 9.6 5.6e-22 0.66 0.02 0.97 FALSE
9 YFS Blood APBB1IP 0.08 0.06 lasso 3 0.06 1.3e-18 -14.7 -14.7 4.2e-49 -0.57 1.00 0.00 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma APBB1IP 0.04 0.03 blup 103 0.03 4.6e-06 15.5 13.7 1.2e-42 0.82 0.02 0.98 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma APBB1IP 0.06 0.07 lasso 2 0.06 1.0e-07 14.7 14.8 1.2e-49 0.94 0.02 0.98 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma APBB1IP 0.08 0.00 blup 103 0.03 5.6e-03 14.7 10.6 5.0e-26 0.71 0.01 0.81 FALSE