Best TWAS P=1.42e-61 · Best GWAS P=3.03e-56 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | APBB1IP | 0.19 | 0.16 | enet | 5 | 0.17 | 2.6e-13 | 15.4 | 15.6 | 7.7e-55 | 0.99 | 0.01 | 0.99 | FALSE |
2 | GTEx | Cells Transformed fibroblasts | APBB1IP | 0.30 | 0.20 | lasso | 10 | 0.20 | 4.9e-15 | 15.6 | 16.6 | 1.4e-61 | 0.98 | 0.00 | 1.00 | TRUE |
3 | GTEx | Esophagus Muscularis | APBB1IP | 0.12 | 0.09 | lasso | 3 | 0.08 | 1.6e-05 | 15.8 | 15.7 | 1.1e-55 | 0.99 | 0.00 | 1.00 | FALSE |
4 | GTEx | Liver | APBB1IP | 0.26 | 0.11 | lasso | 7 | 0.06 | 1.1e-02 | 9.6 | 11.9 | 1.1e-32 | 0.89 | 0.01 | 0.96 | TRUE |
5 | GTEx | Pituitary | APBB1IP | 0.53 | 0.37 | lasso | 8 | 0.38 | 1.6e-10 | 15.5 | 14.5 | 7.0e-48 | 0.97 | 0.02 | 0.98 | FALSE |
6 | GTEx | Stomach | APBB1IP | 0.31 | 0.05 | lasso | 4 | 0.05 | 2.9e-03 | 14.7 | 14.2 | 1.6e-45 | 0.88 | 0.05 | 0.87 | FALSE |
7 | METSIM | Adipose | APBB1IP | 0.07 | 0.04 | lasso | 6 | 0.03 | 8.2e-06 | 15.8 | 15.3 | 5.5e-53 | 0.99 | 0.00 | 1.00 | FALSE |
8 | ROSMAP | Brain Pre-frontal Cortex | APBB1IP | 0.07 | 0.04 | blup | 485 | 0.03 | 1.2e-04 | 14.7 | 9.6 | 5.6e-22 | 0.66 | 0.02 | 0.97 | FALSE |
9 | YFS | Blood | APBB1IP | 0.08 | 0.06 | lasso | 3 | 0.06 | 1.3e-18 | -14.7 | -14.7 | 4.2e-49 | -0.57 | 1.00 | 0.00 | FALSE |
10 | The Cancer Genome Atlas | Breast Invasive Carcinoma | APBB1IP | 0.04 | 0.03 | blup | 103 | 0.03 | 4.6e-06 | 15.5 | 13.7 | 1.2e-42 | 0.82 | 0.02 | 0.98 | FALSE |
11 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | APBB1IP | 0.06 | 0.07 | lasso | 2 | 0.06 | 1.0e-07 | 14.7 | 14.8 | 1.2e-49 | 0.94 | 0.02 | 0.98 | FALSE |
12 | The Cancer Genome Atlas | Stomach Adenocarcinoma | APBB1IP | 0.08 | 0.00 | blup | 103 | 0.03 | 5.6e-03 | 14.7 | 10.6 | 5.0e-26 | 0.71 | 0.01 | 0.81 | FALSE |