TWAS hub - APBB1IP

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1903	0.0448	3.5e-07	0.164	NA	0.170	NA	0.163	8.1e-13	NA	2.6e-13	NA	8.6e-13
2	GTEx	Cells Transformed fibroblasts	0.2980	0.0530	2.1e-12	0.204	NA	0.177	NA	0.201	2.8e-15	NA	2.7e-13	NA	4.9e-15
3	GTEx	Esophagus Muscularis	0.1190	0.0440	1.3e-03	0.091	NA	0.053	NA	0.079	3.8e-06	NA	3.6e-04	NA	1.6e-05
4	GTEx	Liver	0.2640	0.0950	5.9e-03	0.109	NA	0.033	NA	0.058	6.0e-04	NA	4.2e-02	NA	1.1e-02
5	GTEx	Pituitary	0.5270	0.0970	3.7e-06	0.371	NA	0.379	NA	0.380	2.9e-10	NA	1.7e-10	NA	1.6e-10
6	GTEx	Stomach	0.3090	0.0970	6.0e-04	0.048	NA	0.035	NA	0.046	2.5e-03	NA	8.8e-03	NA	2.9e-03
7	METSIM	Adipose	0.0669	0.0230	3.4e-04	0.035	0.015	0.021	0.026	0.033	4.2e-06	1.8e-03	3.6e-04	7.0e-05	8.2e-06
8	ROSMAP	Brain Pre-frontal Cortex	0.0666	0.0243	6.2e-04	0.035	0.029	0.021	0.026	0.024	2.0e-05	1.2e-04	8.9e-04	2.4e-04	3.5e-04
9	YFS	Blood	0.0777	0.0171	7.1e-12	0.061	0.037	0.050	0.053	0.059	2.9e-19	2.6e-12	4.3e-16	9.3e-17	1.2e-18
10	TCGA	Breast Invasive Carcinoma	0.0375	0.0137	1.6e-05	0.030	0.025	0.017	NA	0.023	7.0e-07	4.6e-06	1.5e-04	NA	1.4e-05
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0558	0.0196	9.6e-06	0.073	0.045	0.057	NA	0.064	1.3e-08	7.2e-06	4.5e-07	NA	1.0e-07
12	TCGA	Stomach Adenocarcinoma	0.0850	0.0390	4.5e-03	-0.003	0.025	0.010	NA	0.006	6.4e-01	5.7e-03	6.0e-02	NA	1.1e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Blood Eosinophil Count	25.8	198.4	275.6	15.6	16.6	15.7	11.9	14.5	14.2	15.3	9.6	-14.7	13.7	14.8	10.6
Blood White Count	4.5	33.6	46.6	6.5	6.8	6.5	4.5	6.0	5.8	6.2	3.5	-6.2	6.3	6.1	3.8
Eye problems/disorders: None of the above	4.5	5.2	7.9	-2.4	-2.5	-2.5	-2.3	-2.3	-2.6	-2.2	-1.0	1.8	-2.0	-2.8	-2.4
Diabetes (mother)	4.1	5.2	8.7	2.8	2.2	2.8	2.5	2.9	1.8	3.0	2.0	0.2	2.2	2.4	1.1
Average weekly fortified wine intake	4.1	4.8	7.6	2.5	2.4	2.4	1.7	2.5	1.3	2.5	2.8	-1.4	2.5	2.2	1.8
HbA1C	3.6	4.0	9.9	-2.0	-1.4	-1.9	-2.3	-2.1	-1.8	-2.2	-2.1	1.2	-3.1	-1.6	-1.6
Rheumatoid Arthritis	3.6	4.9	8.4	2.6	2.4	2.5	2.9	2.5	2.1	2.6	1.4	-1.6	2.0	2.4	0.3
Frequency of depressed mood in last 2 weeks	3.6	5.0	6.9	-2.6	-2.4	-2.5	-2.0	-2.4	-2.2	-2.6	-2.0	2.0	-2.6	-2.2	-0.4
Eye problems/disorders: Cataract	3.3	3.8	7.0	1.8	1.9	1.9	1.8	1.7	2.6	2.0	0.9	-1.4	1.8	2.3	2.6
Mouth/teeth dental problems: Bleeding gums	3.0	3.8	5.8	2.3	2.4	2.4	1.7	2.2	1.6	2.2	1.7	-1.8	1.5	2.1	1.0
Asthma (self-reported)	3.0	6.0	9.5	2.9	2.4	2.9	2.6	3.1	2.8	2.8	1.5	0.0	3.0	2.5	0.6
Pulse rate	2.8	4.8	12.6	-2.2	-2.1	-2.1	-2.7	-2.0	-2.4	-2.2	-0.6	1.3	-3.5	-2.2	-1.4
Breast Cancer	2.7	6.4	11.8	-2.5	-3.0	-2.6	-1.9	-2.3	-2.4	-2.4	-1.5	3.4	-1.8	-2.7	-3.1
Asthma	2.7	5.4	8.4	2.7	2.3	2.8	2.4	2.9	2.8	2.6	1.6	-0.2	2.6	2.4	0.6
Pulse wave reflection index	2.7	3.3	6.3	1.8	1.8	1.9	1.1	1.8	2.4	1.7	2.0	-0.4	2.5	2.0	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	2.6	3.3	7.2	-1.8	-2.0	-1.9	-1.5	-1.7	-1.7	-1.9	-2.7	1.8	-1.5	-2.2	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	2.5	3.3	7.4	-1.8	-1.8	-1.9	-2.0	-1.7	-2.0	-1.9	-0.8	1.2	-2.7	-2.1	-1.0
Neuroticism (2016)	2.4	3.4	9.3	-1.8	-1.5	-1.7	-2.3	-2.0	-1.3	-2.1	-3.0	0.2	-1.5	-1.4	-1.9
Bipolar Disorder (2011)	2.2	2.1	4.3	1.3	1.6	1.4	1.4	1.1	1.5	1.6	2.1	-1.7	0.9	1.8	0.1
Depression (Nagel 2018)	2.1	3.1	5.2	-2.0	-1.9	-2.0	-1.7	-2.0	-1.2	-1.9	-1.0	2.1	-2.3	-1.4	-1.0
Worry too long after embarrassment	2.1	3.5	5.0	2.1	2.2	2.1	1.1	1.9	1.9	1.9	1.3	-2.0	2.2	2.1	1.1
Ever had stillbirth, spontaneous miscarriage or termination	2.1	2.2	3.3	-1.6	-1.8	-1.7	-1.4	-1.6	-1.5	-1.8	-1.1	0.9	-0.6	-1.8	-1.6
Fractured/broken bones in last 5 years	2.1	2.7	3.9	1.9	1.8	2.0	1.8	2.0	1.8	1.7	0.6	-0.8	1.8	1.8	0.8
Lupus	2.0	3.0	6.9	1.9	1.6	1.8	2.3	1.9	1.0	1.9	2.6	-0.5	1.8	1.6	1.0
Ever had hysterectomy (womb removed)	2.0	2.3	3.6	-1.6	-1.8	-1.6	-0.8	-1.4	-1.9	-1.5	-0.4	1.8	-1.6	-1.8	-1.0
Medication: Allopurinol	2.0	2.6	5.4	1.9	1.7	1.9	1.2	1.8	2.0	1.7	0.7	-0.3	2.3	1.8	0.3
Bilateral oophorectomy (both ovaries removed)	1.9	2.2	4.5	-1.4	-1.8	-1.4	-0.2	-1.1	-2.1	-1.4	-0.5	2.1	-1.4	-1.6	-1.7
Diverticular disease/diverticulitis (self-reported)	1.9	2.3	3.7	-1.5	-1.2	-1.6	-1.6	-1.7	-1.9	-1.6	-1.2	-0.8	-1.8	-1.7	-0.9
Ulcerative Colitis (UC)	1.8	3.4	5.9	1.9	1.5	1.9	1.4	2.1	2.3	2.0	0.7	0.6	2.4	1.9	2.4
Prostate Cancer	1.8	2.5	4.6	-1.4	-1.4	-1.4	-1.4	-1.4	-2.1	-1.6	-0.2	0.8	-1.9	-2.1	-2.0
Severe depression (siblings)	1.8	2.1	3.3	1.5	1.7	1.5	1.5	1.5	1.7	1.2	0.9	-1.8	0.9	1.3	1.3
Breastfed as a baby	1.7	2.1	3.7	-1.6	-1.6	-1.6	-1.3	-1.4	-1.3	-1.6	-0.9	1.2	-1.9	-1.5	-1.4
Number of children fathered	1.7	1.9	7.0	1.0	1.2	1.1	0.7	0.9	2.1	1.2	1.6	-0.5	0.1	1.4	2.6
Supplements: Calcium	1.7	1.8	3.8	1.5	1.3	1.5	1.5	1.5	1.7	1.5	0.2	-0.1	1.9	1.3	0.9
Medication: Co-codamol	1.6	1.9	3.6	-1.3	-1.3	-1.3	-1.0	-1.3	-1.1	-1.5	-1.6	0.8	-1.8	-1.3	-1.9
Noisy workplace	1.6	2.0	3.6	1.5	1.6	1.6	1.4	1.6	0.9	1.4	1.9	-1.2	1.3	1.5	0.5
Illnesses of father: Heart disease	1.6	2.2	4.8	1.5	1.4	1.5	1.5	1.6	1.3	1.6	1.3	-0.5	2.2	1.5	0.9
Medication for pain relief, constipation, heartburn	1.5	2.6	4.7	-1.8	-1.4	-1.9	-1.8	-1.8	-1.9	-2.2	-0.3	-0.7	-1.0	-1.8	-1.9
Schizophrenia (2018)	1.4	2.9	6.3	1.8	1.7	1.7	1.8	1.9	1.7	1.9	-0.0	-0.6	1.3	2.1	2.5
Fasting Glucose	1.4	1.7	3.0	1.6	1.5	1.4	1.7	1.5	0.9	1.4	1.0	-0.9	1.4	1.1	0.4
Respiratory disease	1.4	3.2	5.4	2.3	2.1	2.2	1.5	2.3	1.9	1.9	0.9	-1.4	1.7	1.7	0.1
Chronic bronchitis/emphysema (mother)	1.4	1.6	3.4	-1.2	-1.0	-1.2	-1.9	-1.4	-0.9	-1.4	-1.9	-0.2	-0.6	-1.0	-1.6
Smoking status: Current	1.4	2.2	3.0	-1.5	-1.5	-1.6	-1.4	-1.3	-1.6	-1.7	1.2	0.3	-1.6	-1.7	-1.7
Mouth/teeth dental problems	1.3	2.0	4.5	-1.5	-1.2	-1.6	-2.1	-1.6	-1.6	-1.8	-1.2	-0.7	-0.6	-1.7	-0.5
Commuting to job workplace: Walk	1.3	1.4	3.2	-1.1	-0.8	-1.0	-1.6	-1.2	-1.7	-1.1	-0.9	-0.1	-1.8	-1.0	-1.2
Mineral and other dietary supplements	1.3	1.7	3.2	-1.4	-1.6	-1.3	-0.5	-1.3	-0.7	-1.3	-1.4	1.8	-1.5	-1.1	-1.3
Alcohol drinker status: Never	1.3	1.6	5.4	-0.9	-0.6	-0.9	-1.3	-1.0	-1.4	-1.3	0.0	-1.4	-1.5	-1.2	-2.3
Age at First Birth	1.2	1.7	3.1	1.5	1.7	1.7	0.6	1.2	1.2	1.6	-0.4	-1.5	1.4	1.3	0.7
Medication: Metformin	1.2	1.7	2.8	-1.4	-1.5	-1.4	-1.3	-1.5	-0.7	-1.3	-1.7	1.3	-1.2	-1.1	-0.6
Current tobacco smoking	1.2	2.0	3.2	-1.5	-1.6	-1.6	-1.2	-1.3	-1.4	-1.7	0.9	0.7	-1.5	-1.6	-1.8
Gout (self-reported)	1.2	1.6	3.6	1.4	1.1	1.5	1.2	1.4	1.4	1.5	1.1	0.3	1.9	1.1	0.5
Number of full sisters	1.2	1.5	3.3	-1.3	-1.4	-1.3	-0.7	-1.1	-1.0	-1.5	0.6	1.2	-1.8	-1.4	-0.6
Primary Biliary Cirrhosis	1.1	1.6	4.0	1.3	1.1	1.3	1.6	1.5	1.2	1.5	2.0	0.2	0.8	1.2	0.5
Ulcerative Colitis	1.1	1.7	4.9	1.2	1.1	1.2	0.7	1.3	1.7	1.1	-0.4	-0.1	1.5	1.5	2.2
Fed-up feelings	1.1	2.0	4.5	-1.6	-1.6	-1.5	-2.1	-1.5	-1.3	-1.5	-0.0	1.7	-0.8	-1.1	-1.1
Taking other prescription medications	1.1	1.6	3.7	1.4	1.1	1.5	1.0	1.4	1.9	1.4	-0.7	0.9	1.0	1.5	0.6
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	2.9	-1.6	-1.6	-1.5	-1.1	-1.4	-1.4	-1.7	-0.1	1.4	-1.1	-1.4	-0.7
Qualifications: None of the above	1.1	2.4	4.9	-1.8	-1.6	-1.7	-1.7	-1.7	-1.4	-1.8	-0.0	0.7	-1.2	-1.7	-2.2
Supplements: Vitamin C	1.1	1.3	2.2	1.4	1.3	1.2	0.9	1.4	1.0	0.9	0.9	-1.3	0.9	1.0	1.5
Waist Hip Ratio (WHR)	1.0	4.4	8.2	-2.3	-2.2	-2.2	-2.9	-2.3	-2.6	-2.4	-1.5	1.2	-1.4	-2.0	-1.3
Townsend deprivation index at recruitment	1.0	1.4	3.1	-0.9	-1.0	-1.1	-0.9	-0.8	-1.8	-1.3	-1.1	-0.1	-1.4	-1.6	-1.2
Waist circumference	1.0	3.5	5.8	-1.9	-2.0	-2.0	-2.4	-1.9	-2.0	-2.0	-1.3	1.4	-1.9	-2.0	-1.4
Medication: Ramipril	1.0	1.2	5.5	-1.1	-1.2	-1.0	-0.8	-1.0	0.1	-0.9	-2.3	1.3	0.2	-0.9	-0.9
Depression (self-reported)	1.0	1.2	3.7	-1.0	-1.0	-1.1	-1.0	-0.9	-1.1	-1.4	-1.9	0.4	-0.5	-1.2	-0.7
Medication: Lansoprazole	1.0	1.1	2.0	1.0	1.2	1.2	0.2	1.2	1.3	1.2	0.7	-0.1	1.1	1.4	0.9
Number of full brothers	1.0	1.3	2.8	-1.0	-0.8	-1.1	-1.2	-1.1	-1.6	-1.2	-0.1	-0.9	-0.8	-1.7	-1.1
Shortness of breath walking on level ground	1.0	1.2	3.0	1.3	1.1	1.3	0.7	1.4	1.7	1.1	0.7	0.2	1.0	1.2	0.9
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.0	3.4	-1.5	-1.6	-1.6	-1.8	-1.5	-1.2	-1.6	-0.4	1.6	-1.3	-1.4	-0.3
Mood swings	1.0	1.8	2.9	-1.3	-1.5	-1.3	-1.5	-1.2	-1.3	-1.4	-0.9	1.5	-0.9	-1.3	-1.7
Osteoarthritis (self-reported)	1.0	1.2	1.9	1.3	1.4	1.3	0.4	1.1	1.0	1.3	0.9	-1.0	1.3	1.2	-0.3
Illnesses of father: None of the above (group 1)	1.0	1.2	2.1	-0.9	-1.1	-1.1	-1.0	-0.9	-1.1	-1.4	-1.3	0.5	-1.3	-1.4	-0.9
Crohns Disease (2017)	0.9	2.1	7.6	-1.6	-1.8	-1.6	-1.2	-1.5	-1.1	-1.1	-0.5	2.8	-0.2	-1.4	-0.7
Chronic bronchitis/emphysema (father)	0.9	1.0	2.6	-1.1	-0.7	-1.0	-1.5	-1.1	-0.9	-1.1	0.1	-0.4	-1.6	-0.7	-0.9
Comparative body size at age 10	0.9	2.5	4.5	1.6	1.8	1.6	1.1	1.4	1.6	1.5	1.7	-2.1	0.8	1.6	1.9
Mother’s age at death	0.9	1.1	2.7	-1.0	-0.8	-1.0	-0.9	-1.0	-1.6	-0.9	-1.4	-0.2	-1.2	-1.2	-1.0
Medication: Blood pressure	0.9	1.7	2.8	1.3	1.3	1.5	1.4	1.4	1.7	1.2	0.4	-0.6	1.6	1.4	1.1
Medication: Bendroflumethiazide	0.9	1.3	3.0	0.9	1.2	1.1	0.7	0.8	1.7	0.9	1.2	-1.4	1.4	1.5	0.3
Alzheimer’s Disease (in mother)	0.8	0.9	2.6	0.9	0.9	0.8	0.2	0.8	0.6	0.8	1.3	-1.4	1.6	0.5	0.8
Ovarian Cancer	0.8	1.0	5.2	-0.4	-0.3	-0.5	-0.9	-0.4	-1.8	-0.6	-0.2	-0.5	-0.8	-1.0	-2.3
LDL Cholesterol	0.8	1.3	2.6	-1.3	-1.1	-1.3	-1.0	-0.9	-1.4	-1.4	0.6	0.7	-1.0	-0.8	-1.6
Diabetes (father)	0.8	1.0	3.0	0.9	1.1	0.9	1.0	0.6	0.5	1.0	1.3	-1.7	0.7	0.7	1.2
Had menopause	0.8	1.1	4.2	-0.8	-1.1	-0.8	-0.5	-0.6	-0.5	-0.9	-1.1	2.0	0.8	-0.8	-1.3
Mouth/teeth dental problems: Dentures	0.8	1.4	4.4	0.9	0.6	0.9	2.1	1.1	1.5	1.2	1.2	1.4	0.6	1.4	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.3	0.8	0.5	0.9	0.8	0.8	1.0	1.2	0.4	0.8	1.5	0.9	1.4
Impedance of arm (left)	0.8	3.7	5.4	2.0	2.1	2.0	1.8	1.8	1.9	2.0	1.3	-1.6	1.9	2.3	1.9
Emphysema/chronic bronchitis	0.8	0.9	2.3	-0.7	-0.8	-0.8	-0.8	-0.8	-1.4	-0.9	-0.1	0.6	-1.5	-1.0	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	3.7	0.8	1.0	1.0	0.2	0.7	1.1	0.6	1.9	-0.7	0.4	1.3	0.7
Ever had prostate specific antigen (PSA) test	0.8	1.0	1.5	-1.1	-1.1	-1.0	-1.0	-1.1	-1.1	-0.7	-1.1	1.2	-1.1	-0.8	0.6
Pain experienced in last month	0.8	1.3	8.1	0.8	1.3	0.8	0.6	0.6	0.4	0.9	0.4	-2.9	0.4	0.8	1.3
Depressed Affect (Nagel 2018)	0.7	1.5	3.4	-1.4	-1.4	-1.3	-1.8	-1.4	-0.7	-1.3	-0.0	1.3	-0.3	-0.9	-1.3
Type 2 Diabetes (T2D) (2012)	0.7	0.9	2.4	0.9	1.1	1.3	0.6	1.1	0.7	0.9	1.6	-0.6	-0.1	1.0	0.1
Hearing difficulty/problems: Yes	0.7	1.0	2.2	-1.0	-1.2	-1.1	-0.7	-1.0	-1.5	-1.1	-0.4	0.7	-0.2	-1.2	-1.3
Ever used hormone-replacement therapy (HRT)	0.7	0.9	4.3	0.7	0.5	0.8	1.2	0.6	0.4	1.1	1.0	0.5	2.1	0.4	-0.4
Vitamin and mineral supplements	0.7	1.0	2.2	-1.3	-1.4	-1.2	-0.3	-1.1	-0.9	-0.8	-0.5	1.5	-0.5	-0.8	-0.5
Serious illness, injury or assault to yourself	0.7	0.8	1.2	1.1	1.0	1.1	0.9	1.1	1.0	0.9	-0.8	-0.3	0.7	1.0	-0.6
Supplements: Glucosamine	0.7	0.9	1.8	1.2	1.1	1.1	0.2	1.1	0.7	1.0	1.0	-0.6	1.3	1.0	0.6
Hair/balding pattern: Pattern 2	0.7	0.9	2.0	1.1	0.9	1.1	0.9	1.3	-0.0	0.9	1.0	0.0	1.4	0.7	1.2
Medication: Paracetamol	0.7	1.1	2.1	1.1	0.7	1.2	1.5	1.2	0.9	1.2	1.1	1.2	0.2	1.2	-0.1
Heart disease (mother)	0.7	0.9	2.2	0.7	1.0	0.9	0.2	0.6	1.2	0.8	1.2	-0.9	1.5	1.2	0.3
Hypertension (Self-reported)	0.7	1.9	3.5	1.3	1.3	1.5	0.8	1.2	1.8	1.3	-0.5	-0.4	1.9	1.8	1.9
Medication for cholesterol	0.7	1.0	3.0	-0.8	-0.8	-1.0	-1.1	-0.9	-1.4	-0.9	-0.6	0.2	-1.7	-1.0	-0.6
Medication: Aspirin	0.7	0.9	4.5	0.8	0.6	0.8	1.0	0.9	1.2	1.0	-0.1	0.1	0.4	0.5	2.1
Hearing aid user	0.7	0.8	1.9	-0.8	-1.0	-1.0	-0.8	-0.8	-1.4	-1.1	-0.3	0.5	-0.4	-0.9	-0.8
Tinnitus: Yes, now most or all of the time	0.7	0.8	7.0	0.2	0.6	0.1	0.3	0.1	-0.2	0.1	1.0	-2.6	-0.5	0.0	0.6
Irritable Bowel Disease (IBD)	0.6	1.4	3.8	0.9	0.6	0.9	0.8	1.1	1.4	1.2	0.3	1.6	2.0	1.0	1.6
BMI	0.6	3.6	5.1	-1.8	-2.1	-1.8	-1.8	-1.8	-1.9	-1.7	-1.9	2.2	-1.8	-2.0	-1.8
Smoking Status	0.6	1.5	2.0	-1.3	-1.4	-1.3	-1.1	-1.2	-1.4	-1.2	0.9	1.2	-0.9	-1.4	-1.2
Number of treatments/medications taken	0.6	1.0	2.2	0.9	0.6	1.1	0.5	0.8	1.2	1.0	-1.1	1.1	1.5	1.1	0.9
Financial difficulties in last 2 years	0.6	0.8	1.9	-0.7	-0.4	-0.7	-1.2	-0.7	-0.4	-1.2	0.3	-1.1	-1.0	-0.8	-1.4
Pain all over the body in last month	0.6	0.6	1.7	-0.5	-0.7	-0.5	-0.4	-0.4	-1.0	-0.4	0.2	1.3	-1.3	-0.6	-1.2
Impedance of arm (right)	0.6	2.8	3.9	1.8	1.9	1.8	1.8	1.6	1.6	1.7	1.4	-1.5	1.2	2.0	1.5
Time employed in main current job	0.6	0.7	1.3	-1.1	-1.0	-1.0	-0.9	-1.2	-0.3	-0.9	-0.4	1.1	-0.2	-0.6	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	7.4	0.3	-0.2	0.4	1.2	0.7	0.5	0.5	0.8	2.7	0.4	0.5	0.7
Number of live births	0.6	0.9	2.4	-0.9	-1.0	-0.9	-0.4	-0.9	-1.5	-0.7	-0.4	0.1	-0.9	-1.4	-1.3
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.6	-0.6	-0.5	-0.7	-1.1	-0.6	-0.9	-1.0	-0.4	-0.2	-1.2	-0.8	-1.3
Arm fat-free mass (right)	0.6	3.0	5.3	-1.8	-2.1	-1.9	-1.7	-1.6	-1.6	-1.9	-1.1	2.3	-1.5	-2.0	-0.8
Medication: Ibuprofen	0.6	0.7	2.6	0.7	0.6	0.8	0.3	0.7	1.1	1.0	0.2	0.3	0.9	0.9	1.6
Arm predicted mass (right)	0.6	3.3	4.6	-1.9	-2.1	-2.0	-1.9	-1.8	-1.7	-2.0	-1.6	2.1	-1.5	-2.1	-0.9
Alcohol intake frequency.	0.6	1.4	2.9	-1.0	-0.8	-1.0	-1.2	-1.1	-1.6	-1.2	0.3	-0.3	-1.4	-1.4	-1.7
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.0	0.7	0.5	0.7	1.1	0.6	1.2	0.9	0.2	0.2	1.4	0.9	0.3
Average weekly red wine intake	0.6	0.8	1.3	0.9	0.7	1.0	1.1	1.0	0.9	1.0	0.7	0.1	0.9	1.1	1.1
Qualifications: nursing, teaching	0.6	1.0	3.7	0.7	0.2	0.8	0.8	0.9	0.5	1.0	0.5	1.8	1.9	0.8	-0.0
Average weekly champagne plus white wine intake	0.6	0.9	2.0	1.0	1.0	1.0	0.6	1.0	0.9	1.0	0.4	-0.3	1.4	1.0	1.0
Unable to work because of sickness or disability	0.6	0.8	1.9	-1.1	-1.0	-1.1	-1.4	-1.0	-0.4	-1.3	-0.3	0.2	-0.6	-0.8	-0.5
Commuting to job workplace: Cycle	0.6	0.8	4.4	-0.3	0.1	-0.4	-1.3	-0.5	-0.8	-0.4	-0.3	-2.1	-0.6	-0.8	-0.7
Leg fat mass (left)	0.6	2.5	4.1	-1.4	-1.8	-1.6	-1.7	-1.4	-1.7	-1.5	-1.4	2.0	-1.3	-1.8	-1.1
Alzheimer’s Disease (in father)	0.5	0.6	1.6	-0.6	-0.4	-0.6	-0.7	-0.6	-1.3	-0.4	-1.3	-0.5	-0.6	-1.1	-0.1
Body Mass Index (BMI) (2010)	0.5	0.7	2.8	-0.9	-0.7	-0.8	-1.1	-1.0	-0.5	-0.7	-0.6	0.4	-0.1	-0.4	-1.7
HDL Cholesterol	0.5	0.9	3.4	0.8	0.4	0.9	1.9	1.1	0.6	0.8	0.9	0.8	0.6	0.4	1.2
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	2.1	0.6	0.2	0.5	1.3	0.7	0.3	0.7	0.5	1.4	0.5	0.6	-0.3
Body mass index (BMI)	0.5	2.0	3.3	-1.2	-1.6	-1.3	-1.4	-1.2	-1.4	-1.3	-1.0	1.8	-1.5	-1.6	-1.3
Number of incorrect matches in round	0.5	0.8	2.1	0.7	0.8	0.8	1.2	0.8	0.5	0.7	1.5	-0.2	1.3	0.9	0.6
Nervous feelings	0.5	0.9	1.7	0.8	1.1	0.9	0.3	0.7	1.2	0.7	0.1	-1.3	1.3	1.1	1.1
Glaucoma (self-reported)	0.5	0.5	2.3	-0.7	-0.5	-0.6	-1.5	-0.9	-0.4	-0.7	-1.0	0.1	0.2	-0.5	-0.5
High blood pressure (siblings)	0.5	0.7	4.4	-0.5	-0.6	-0.6	0.6	-0.2	-0.7	-0.3	-1.1	0.4	-2.1	-0.8	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	4.5	-0.6	-0.9	-0.5	-0.3	-0.4	-0.4	-0.4	-0.3	2.1	0.3	-0.4	-1.0
Age at last live birth	0.5	0.7	4.7	-0.5	-0.5	-0.5	-0.7	-0.6	-1.0	-0.3	-2.2	0.2	-0.5	-0.7	0.5
Medication: Aspirin	0.5	0.7	3.2	0.7	0.4	0.6	0.9	0.7	1.2	0.8	-0.1	0.6	0.3	0.4	1.8
Illnesses of siblings: Diabetes	0.5	0.7	2.2	0.8	1.0	0.8	0.3	0.8	0.8	0.4	-0.8	-1.5	-0.1	1.0	0.7
Smoking status: Previous	0.5	0.7	1.9	0.7	0.6	0.7	1.1	0.6	1.4	1.1	-0.2	0.4	1.3	1.0	0.2
Leg fat-free mass (right)	0.5	2.5	6.4	-1.5	-1.9	-1.6	-1.6	-1.2	-1.3	-1.8	-0.7	2.5	-1.5	-1.8	-0.9
Handedness (chirality/laterality): Left-handed	0.5	0.6	3.1	-0.8	-0.5	-0.7	-0.5	-1.0	-0.6	-0.7	-0.1	-0.6	-1.8	-0.5	-0.6
Medication: Gliclazide	0.5	0.5	1.2	0.5	0.3	0.5	0.9	0.4	0.8	0.9	1.1	0.8	1.0	0.9	0.1
Leg predicted mass (right)	0.5	2.6	5.9	-1.5	-1.9	-1.7	-1.7	-1.3	-1.4	-1.8	-0.6	2.4	-1.6	-1.8	-0.9
Miserableness	0.5	0.9	2.3	-1.0	-1.1	-1.0	-0.9	-1.0	-1.0	-0.8	-0.1	1.0	-0.1	-0.8	-1.5
Pain type(s) experienced in last month: Hip pain	0.5	0.7	3.9	0.5	1.0	0.7	-0.3	0.3	0.7	0.4	0.7	-2.0	-0.5	0.9	-0.2
Ever smoked	0.5	0.8	3.1	-0.9	-1.2	-0.9	-0.2	-0.8	-0.8	-0.7	0.3	1.8	-0.5	-0.8	-1.0
Vascular/heart problems diagnosed by doctor	0.5	1.4	2.7	-1.1	-1.3	-1.3	-0.5	-1.0	-1.6	-1.1	0.7	0.7	-1.3	-1.6	-1.5
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	3.2	-0.6	-0.1	-0.3	-1.0	-0.7	-0.3	-0.4	-0.1	-0.6	-1.8	-0.3	-0.9
Impedance of whole body	0.5	2.5	3.6	1.5	1.7	1.6	1.7	1.3	1.3	1.7	1.0	-1.6	1.8	1.9	1.6
Arm predicted mass (left)	0.5	2.8	4.3	-1.6	-1.9	-1.7	-1.6	-1.4	-1.7	-1.8	-1.1	2.1	-1.6	-2.0	-1.0
Bipolar Disorder or Schizophrenia	0.4	0.9	1.9	0.9	1.0	0.9	1.4	0.8	0.9	1.1	-0.2	-0.6	0.1	1.4	1.3
Leg fat-free mass (left)	0.4	2.2	4.9	-1.3	-1.7	-1.5	-1.5	-1.2	-1.2	-1.7	-0.8	2.2	-1.5	-1.7	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	5.4	0.6	0.7	0.4	0.6	0.5	-0.7	0.5	2.3	-1.5	-0.7	0.4	-0.7
High blood pressure	0.4	1.2	2.6	0.8	1.0	1.0	0.2	0.7	1.5	0.8	-1.0	-0.3	1.5	1.4	1.6
Leg predicted mass (left)	0.4	2.1	4.3	-1.3	-1.7	-1.5	-1.5	-1.2	-1.2	-1.6	-0.7	2.1	-1.4	-1.7	-0.8
Allergy	0.4	0.9	1.7	-1.2	-1.1	-1.1	-1.2	-1.3	-0.0	-0.9	-0.9	1.3	-0.7	-0.4	-0.3
Weight	0.4	2.1	3.5	-1.4	-1.6	-1.5	-1.6	-1.3	-1.4	-1.5	-1.2	1.9	-1.5	-1.6	-0.8
Hair/balding pattern: Pattern 3	0.4	0.5	2.8	-0.4	-0.1	-0.5	-0.6	-0.7	-0.3	-0.4	-0.7	-1.7	-1.1	-0.5	-0.6
Illnesses of mother	0.4	0.4	2.5	0.6	0.6	0.5	0.9	0.6	0.4	0.5	0.0	-0.5	0.3	0.2	1.6
Pulse wave Arterial Stiffness index	0.4	0.4	2.2	-0.7	-0.5	-0.6	-1.5	-0.8	-0.3	-0.7	-0.5	-0.4	-0.2	-0.4	-0.5
Arm fat mass (right)	0.4	1.8	3.5	-1.1	-1.5	-1.2	-1.5	-1.1	-1.4	-1.3	-1.0	1.9	-1.6	-1.5	-1.1
Birth weight of first child	0.4	0.7	1.7	-1.0	-0.7	-1.0	-0.6	-1.2	-0.3	-0.7	-1.3	0.1	-0.7	-0.5	-0.9
Loud music exposure frequency	0.4	0.4	0.9	0.8	0.7	0.7	0.8	0.8	0.2	0.6	0.9	0.0	-0.6	0.7	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.8	0.6	0.8	0.7	-0.1	0.4	0.7	0.8	1.4	-0.3	0.2	1.1	0.1
Pulse wave peak to peak time	0.4	0.5	2.2	0.8	0.6	0.6	1.5	0.8	0.2	0.7	0.4	0.1	0.1	0.4	0.7
Mouth/teeth dental problems: Loose teeth	0.4	0.5	3.3	0.5	0.3	0.4	0.5	0.5	0.3	0.3	1.8	0.4	0.3	0.2	-1.0
Mean time to correctly identify matches	0.4	0.8	6.6	-0.3	-0.5	-0.2	-0.3	-0.3	0.3	0.0	-2.6	1.6	0.5	-0.0	0.2
Leg fat mass (right)	0.4	1.7	2.7	-1.2	-1.5	-1.3	-1.4	-1.1	-1.4	-1.2	-1.3	1.6	-1.2	-1.5	-0.9
Knee pain experienced in last month	0.4	0.7	4.5	-0.6	-0.9	-0.6	-0.4	-0.5	-0.2	-0.5	1.0	2.1	0.5	-0.2	-0.5
Whole body fat-free mass	0.4	2.4	3.3	-1.5	-1.8	-1.6	-1.8	-1.4	-1.4	-1.8	-1.1	1.8	-1.7	-1.8	-0.7
Whole body water mass	0.4	2.5	3.5	-1.5	-1.8	-1.7	-1.8	-1.4	-1.4	-1.8	-1.1	1.9	-1.7	-1.9	-0.7
Arm fat mass (left)	0.4	1.5	3.5	-0.9	-1.3	-1.0	-1.4	-0.9	-1.2	-1.1	-0.8	1.9	-1.2	-1.3	-1.0
Number of self-reported non-cancer illnesses	0.4	0.7	2.0	0.7	0.6	0.9	0.4	0.7	1.1	0.9	0.2	0.6	1.4	1.0	0.6
Wears glasses or contact lenses	0.4	0.4	1.8	0.5	0.8	0.5	0.4	0.4	0.4	0.4	-0.8	-1.4	-0.6	0.5	0.6
Basal metabolic rate	0.4	2.3	3.7	-1.4	-1.8	-1.6	-1.7	-1.3	-1.4	-1.7	-1.0	1.9	-1.6	-1.8	-0.8
Arm fat-free mass (left)	0.4	2.2	3.2	-1.4	-1.7	-1.6	-1.6	-1.3	-1.4	-1.6	-1.1	1.8	-1.6	-1.7	-0.7
Average weekly beer plus cider intake	0.4	0.6	2.7	-0.5	-0.6	-0.6	-0.5	-0.6	-0.8	-0.8	0.7	-0.2	-1.1	-0.8	-1.6
Myopia	0.4	0.6	1.3	0.9	0.4	0.9	-0.1	1.1	0.1	1.1	0.4	1.1	0.8	0.5	0.5
Alcohol drinker status: Previous	0.4	0.4	1.4	-0.4	-0.3	-0.4	-0.7	-0.6	-1.0	-0.6	-0.6	-0.2	-0.7	-0.5	-1.2
Bipolar Disorder (2018)	0.3	0.5	2.5	-0.8	-0.5	-0.7	-0.1	-1.0	-0.7	-0.6	-0.3	-0.2	-1.6	-0.4	-0.7
Alzheimer’s Disease (including proxy)	0.3	0.4	1.7	0.2	0.4	0.2	0.1	0.3	-0.0	0.4	0.5	-1.3	1.2	-0.1	1.2
Reaction Time	0.3	0.6	4.7	0.2	0.2	0.2	0.1	-0.0	0.9	0.3	-2.2	0.2	0.8	0.4	0.5
Verbal and Numeric Reasoning (VNR)	0.3	0.8	2.8	1.1	0.8	1.0	0.4	1.1	0.4	0.9	0.5	-0.2	1.7	0.9	0.9
Crohns Disease (2012)	0.3	0.4	1.8	-0.8	-0.8	-0.7	-0.4	-0.8	-0.1	-0.4	-0.2	1.3	-0.3	-0.5	0.2
Mean Putamen Volume	0.3	0.4	1.2	0.5	0.4	0.4	0.4	0.5	-0.9	0.6	0.8	-0.4	0.2	-0.1	1.1
Systolic Blood Pressure	0.3	1.7	3.6	1.3	1.3	1.5	0.6	1.3	1.3	1.6	-1.0	-0.3	1.2	1.5	1.9
Hypothyroidism (self reported)	0.3	0.7	1.3	-0.8	-0.8	-0.8	-1.0	-0.9	-1.2	-0.7	-0.9	0.6	0.6	-0.8	-0.7
Pack years adult smoking proportion	0.3	0.4	2.5	-0.1	0.2	-0.2	-0.5	-0.3	-0.3	-0.3	0.9	-1.6	0.1	0.0	-0.9
Impedance of leg (right)	0.3	1.4	5.7	0.9	1.3	1.0	1.0	0.6	0.6	1.1	0.1	-2.4	1.3	1.2	1.4
Relative age voice broke	0.3	0.4	0.7	-0.8	-0.6	-0.8	-0.8	-0.7	-0.3	-0.8	-0.2	0.5	-0.5	-0.7	-0.4
Qualifications: CSEs or equivalent	0.3	0.4	1.8	0.3	0.4	0.4	0.4	0.3	0.9	0.4	1.4	-0.0	-0.1	0.7	0.8
Stomach or abdominal pain in last month	0.3	0.4	0.6	-0.7	-0.7	-0.7	-0.6	-0.7	-0.4	-0.7	-0.1	0.3	-0.7	-0.8	-0.7
High blood pressure (mother)	0.3	0.4	0.8	0.8	0.5	0.8	0.8	0.9	0.6	0.9	0.6	0.1	0.3	0.5	-0.4
Trunk fat mass	0.3	1.1	2.9	-0.9	-1.1	-0.9	-1.3	-0.8	-1.0	-0.9	-0.9	1.7	-0.9	-1.1	-0.3
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	1.9	-0.3	-0.1	-0.2	-0.7	-0.3	0.2	-0.2	-0.4	-0.7	-0.8	-0.0	1.4
Trunk fat-free mass	0.3	1.8	2.6	-1.3	-1.5	-1.4	-1.6	-1.2	-1.2	-1.6	-1.2	1.2	-1.5	-1.6	-0.5
Alcohol intake versus 10 years previously	0.3	0.4	1.9	0.5	0.7	0.6	0.5	0.5	0.6	0.4	1.1	-1.4	0.0	0.3	0.0
Father’s age at death	0.3	0.4	1.6	0.1	0.4	0.2	-0.3	0.0	0.6	0.4	0.8	-0.4	0.9	0.7	1.3
Falls in the last year	0.3	0.4	0.9	0.6	0.7	0.7	-0.3	0.7	0.9	0.5	0.1	-0.3	0.8	0.9	-0.6
Happiness	0.3	0.3	0.8	-0.6	-0.3	-0.5	-0.8	-0.7	-0.7	-0.7	-0.1	-0.6	-0.9	-0.3	0.2
Trunk predicted mass	0.3	1.7	2.5	-1.2	-1.5	-1.4	-1.6	-1.1	-1.2	-1.5	-1.2	1.2	-1.5	-1.6	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	3.7	0.4	0.3	0.3	-0.4	0.4	0.4	0.1	-1.2	0.1	0.5	0.3	1.9
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.3	-0.8	-0.9	-0.8	-0.3	-0.7	-0.8	-0.7	0.4	1.1	-0.1	-0.8	-0.6
Qualifications: College or University degree	0.3	0.9	2.7	0.7	0.5	0.6	0.9	0.7	0.8	0.7	-1.7	0.3	1.1	0.7	1.5
Neck or shoulder pain in last month	0.3	0.4	2.9	-0.0	-0.4	-0.1	0.5	0.2	0.2	-0.1	-0.3	1.7	0.6	-0.1	-0.6
Medication: Blood pressure	0.3	0.5	4.3	-0.1	0.1	0.0	-0.6	-0.2	0.2	0.2	-2.1	0.1	0.6	0.5	0.7
Whole body fat mass	0.3	1.4	3.7	-1.0	-1.3	-1.1	-1.3	-0.9	-1.3	-1.0	-0.9	1.9	-0.9	-1.2	-0.8
Suffer from ‘nerves’	0.3	0.4	1.0	0.5	0.4	0.6	0.3	0.7	0.7	0.4	-0.0	0.8	0.8	0.8	1.0
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.1	-0.8	-0.7	-0.8	-0.3	-1.1	-0.7	-0.3	-0.4	0.1	-0.1	-0.5	0.2
Long-standing illness, disability or infirmity	0.3	0.4	0.7	0.6	0.6	0.7	0.6	0.7	0.9	0.5	0.6	0.2	0.9	0.7	0.2
Friendships satisfaction	0.3	0.3	0.7	0.4	0.4	0.5	0.9	0.4	0.7	0.5	0.5	0.2	0.4	0.8	0.6
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.9	-0.4	-0.5	-0.4	0.1	-0.4	-0.4	-0.2	-1.4	1.0	-1.2	-0.4	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.3	0.6	0.7	0.7	0.2	0.8	0.9	0.7	0.2	0.4	0.2	1.1	0.0
Back pain experienced in last month	0.3	0.5	2.4	-0.4	-0.7	-0.5	-0.0	-0.3	-0.5	-0.6	0.2	1.2	0.2	-0.7	-1.6
Osteoporosis (self-reported)	0.3	0.4	1.0	-0.4	-0.3	-0.4	-0.0	-0.1	-0.8	-0.5	-0.9	-0.3	-1.0	-0.6	-1.0
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.7	0.4	0.6	0.4	-0.0	0.3	-0.5	0.3	0.9	-1.3	0.6	0.1	0.9
High cholesterol (Self-reported)	0.3	0.6	1.6	-0.8	-0.7	-0.7	-0.8	-0.9	-0.7	-0.8	-1.3	0.3	-0.8	-0.9	-0.3
Medication: Paracetamol	0.3	0.5	1.0	0.7	0.4	0.8	0.8	0.8	0.7	0.8	0.4	1.0	-0.0	0.9	-0.2
Medication: Lisinopril	0.3	0.4	1.1	0.7	0.6	0.8	0.4	0.7	0.2	0.8	-0.4	0.0	0.1	0.6	1.0
Illnesses of father: High blood pressure	0.3	0.3	2.2	-0.6	-0.6	-0.4	-0.1	-0.5	0.5	-0.2	-0.0	1.5	0.4	0.2	-0.7
Leg fat percentage (left)	0.3	1.0	2.3	-0.8	-1.1	-0.9	-1.2	-0.8	-1.2	-0.7	-1.0	1.5	-0.6	-1.1	-0.7
Risk taking	0.3	0.5	3.8	0.3	-0.0	0.3	0.0	0.3	0.4	0.4	0.0	1.1	2.0	0.2	-0.5
Basal cell carcinoma (self-reported)	0.3	0.4	3.1	-0.3	-0.1	-0.3	-0.1	-0.1	-0.7	-0.3	0.0	-0.5	-1.8	-0.6	-0.5
Heart disease (siblings)	0.3	0.3	1.6	0.2	0.1	0.2	0.5	0.4	0.7	0.3	-0.2	0.7	0.8	0.3	1.3
Neuroticism (Nagel 2018)	0.2	0.4	1.5	-0.7	-0.6	-0.6	-1.2	-0.8	0.1	-0.6	0.0	0.6	0.2	-0.1	-0.6
Schizophrenia vs Biploar Disorder	0.2	0.2	0.8	-0.3	-0.3	-0.4	-0.1	-0.3	-0.4	-0.1	-0.7	0.5	-0.9	-0.4	-0.7
Worry (Nagel 2018)	0.2	0.5	1.4	0.3	0.5	0.5	-0.2	0.3	1.2	0.4	0.3	0.4	1.0	1.0	0.9
Major Depression (MDD)	0.2	0.2	1.0	0.1	0.3	0.2	-0.5	0.0	1.0	0.0	-0.3	0.2	0.2	0.9	0.6
Coronary Artery Disease (CAD)	0.2	0.3	1.7	-0.4	0.1	-0.1	-0.3	-0.3	0.2	0.1	-1.3	-0.1	-0.9	-0.2	-0.7
Triglycerides	0.2	0.3	1.4	-0.5	-0.5	-0.6	-0.5	-0.4	-0.8	-0.7	0.0	0.1	-0.3	-0.4	-1.2
Height	0.2	3.4	6.7	-1.9	-1.9	-2.0	-1.7	-1.9	-1.8	-2.0	-2.0	1.7	-2.6	-1.6	-0.4
Allergy or Eczema	0.2	0.6	1.1	0.9	0.9	0.9	1.0	0.9	0.4	0.9	0.7	-1.0	-0.1	0.8	0.6
Lung FVC	0.2	0.8	2.9	0.8	1.0	0.8	0.2	0.7	0.2	0.9	0.9	-1.7	-0.2	0.6	1.3
Neuroticism	0.2	0.4	2.0	0.3	0.4	0.5	-0.5	0.2	1.0	0.4	0.6	0.1	1.4	0.7	0.0
Sensitivity / hurt feelings	0.2	0.3	1.6	0.5	0.4	0.6	0.4	0.3	0.5	0.6	0.5	-0.2	1.3	0.3	0.2
Relative age of first facial hair	0.2	0.4	1.1	-0.8	-0.6	-0.8	-0.7	-0.8	-0.2	-0.8	-0.3	0.0	-0.1	-0.8	-1.0
Angina	0.2	0.2	0.7	-0.4	-0.7	-0.4	-0.4	-0.4	-0.5	-0.1	0.4	0.8	-0.0	-0.6	-0.1
Medication for hormone replacement therapy	0.2	0.3	2.0	0.2	0.1	0.2	0.2	0.2	-0.0	0.3	0.6	0.2	1.4	0.2	0.6
Supplements: Zinc	0.2	0.2	0.8	0.2	0.3	0.2	-0.8	0.0	0.7	0.1	-0.9	-0.3	0.7	0.4	0.1
Maternal smoking around birth	0.2	0.2	1.1	-0.4	-0.2	-0.3	-1.0	-0.5	-0.4	-0.6	-0.7	-0.2	0.2	-0.0	-0.2
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.7	-0.0	0.0	-0.0	0.5	0.0	0.8	0.4	0.5	0.4	0.4	0.2	-0.8
Multivitamins +/- minerals	0.2	0.3	0.9	0.7	0.8	0.7	-0.3	0.5	0.3	0.3	0.5	-0.9	0.3	0.3	-0.1
Medication: Atenolol	0.2	0.3	1.1	-0.5	-0.4	-0.3	-1.0	-0.5	-0.1	-0.4	-1.1	-0.1	0.1	0.1	0.6
Sitting height	0.2	1.7	3.9	1.4	1.3	1.3	1.4	1.5	1.3	1.4	0.0	-0.7	1.1	1.4	2.0
Past tobacco smoking	0.2	0.3	2.0	0.4	0.5	0.3	-0.3	0.3	-0.1	-0.0	-0.2	-1.4	-0.4	0.1	0.6
Hearing difficulty/problems with background noise	0.2	0.3	0.8	-0.3	-0.5	-0.4	-0.4	-0.2	-0.7	-0.4	0.8	0.5	0.3	-0.4	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	2.4	0.4	0.5	0.1	0.3	0.3	-0.7	0.3	1.5	-1.3	-0.6	0.2	-1.0
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.7	0.5	0.3	0.4	0.5	0.6	0.3	0.5	-0.6	0.4	0.8	0.4	-0.4
Fluid intelligence score	0.2	0.5	3.6	0.6	0.4	0.5	0.0	0.6	0.3	0.6	-0.6	-0.1	0.2	0.5	1.9
Illnesses of siblings	0.2	0.2	1.0	-0.1	-0.1	0.0	-0.7	-0.2	-0.4	-0.1	0.8	0.3	1.0	-0.2	-0.3
Worrier / anxious feelings	0.2	0.3	1.0	-0.5	-0.5	-0.4	-1.0	-0.5	-0.1	-0.5	-0.2	0.6	-0.2	-0.2	0.9
Medication: Cholesterol lowering	0.2	0.3	2.4	0.1	0.0	0.1	-0.2	-0.0	-0.4	0.2	-1.5	0.1	0.2	-0.1	0.9
Length of working week for main job	0.2	0.2	0.8	0.1	-0.2	0.0	0.6	0.3	0.2	-0.2	0.6	0.7	0.8	0.1	-0.9
Exposure to tobacco smoke at home	0.2	0.3	1.7	-0.1	-0.3	-0.2	0.2	0.2	-0.1	-0.3	-0.6	1.3	-0.7	-0.1	0.3
Hair/balding pattern: Pattern 4	0.2	0.4	1.8	-0.5	-0.6	-0.4	-0.3	-0.3	0.2	-0.6	-1.4	0.9	-1.0	-0.2	0.5
Peak expiratory flow (PEF)	0.2	0.4	1.0	0.8	0.7	0.7	1.0	0.9	0.4	0.6	0.4	-0.5	0.5	0.5	0.6
Blood clot in the leg (DVT)	0.2	0.2	1.5	0.4	0.5	0.3	0.6	0.4	-0.1	0.2	-0.3	-1.2	-0.5	-0.1	-0.1
Headache pain in last month	0.2	0.4	1.4	-0.6	-0.6	-0.6	-0.0	-0.6	-0.5	-0.5	-0.9	0.8	-1.2	-0.4	-0.4
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	2.9	-0.1	-0.2	-0.1	0.3	0.0	-0.0	-0.3	1.7	0.1	-0.3	-0.3	-0.7
Medication: Amlodipine	0.2	0.2	2.0	-0.2	0.1	-0.1	-0.5	-0.2	0.4	-0.2	-0.1	-0.5	0.1	0.2	1.4
Birth weight	0.2	0.3	2.0	0.2	-0.0	0.2	-0.6	0.3	0.5	0.2	0.7	1.4	0.3	0.2	0.8
Exposure to tobacco smoke outside home	0.2	0.3	1.8	0.3	0.4	0.3	0.5	0.2	0.3	0.5	0.6	-0.2	-0.1	0.6	-1.3
Age at first live birth	0.2	0.4	2.1	0.3	0.3	0.4	-0.1	0.2	0.4	0.6	-1.2	0.2	0.8	0.6	1.5
Migraine (self-reported)	0.2	0.3	2.0	0.2	0.1	0.3	0.0	0.1	-0.4	0.4	-0.2	0.4	-0.7	0.1	-1.4
Medication: Omeprazole	0.2	0.3	1.7	0.1	0.4	0.2	-0.3	-0.1	0.1	0.1	-0.4	-0.8	-1.3	0.2	-0.5
Medication: Seretide 50 evohaler	0.2	0.3	1.8	-0.1	-0.2	0.0	-0.2	0.2	0.6	0.1	-0.1	1.3	0.6	0.5	-0.1
Family relationship satisfaction	0.2	0.2	0.9	0.3	0.3	0.3	1.0	0.5	0.3	0.3	1.0	-0.2	0.4	0.2	0.2
Leg pain on walking	0.2	0.2	0.6	0.1	0.4	0.2	-0.8	0.1	0.8	0.0	0.6	-0.6	0.6	0.1	-0.4
Loneliness, isolation	0.2	0.3	0.8	-0.7	-0.7	-0.7	-0.9	-0.6	-0.4	-0.6	-0.2	0.7	-0.2	-0.5	0.3
Ever had bowel cancer screening	0.2	0.3	0.5	0.4	0.4	0.4	0.3	0.4	0.7	0.7	0.5	0.4	0.6	0.5	0.7
Breast cancer (self-reported)	0.2	0.2	0.5	-0.4	-0.4	-0.4	-0.7	-0.6	0.4	-0.6	-0.4	-0.2	0.3	-0.3	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.7	-0.3	-0.2	-0.3	-0.7	-0.4	-1.2	-0.4	-0.4	-0.2	-1.3	-0.5	0.6
Ever taken oral contraceptive pill	0.2	0.2	0.9	-0.3	-0.3	-0.3	-0.6	-0.5	-0.4	-0.3	0.9	-0.1	0.4	-0.4	-0.5
Financial situation satisfaction	0.2	0.3	1.1	-0.3	-0.2	-0.3	-0.7	-0.3	-0.9	-0.4	0.2	-0.3	-1.1	-0.3	-0.2
Medication: Atorvastatin	0.2	0.2	0.5	0.4	0.3	0.5	0.3	0.3	0.7	0.7	-0.2	0.2	0.4	0.5	0.3
Number of operations (self-reported)	0.2	0.2	0.6	-0.5	-0.5	-0.4	-0.3	-0.4	-0.8	-0.7	0.3	0.2	-0.3	-0.7	-0.3
Irritability	0.2	0.3	1.3	-0.3	-0.3	-0.2	-0.9	-0.3	-0.2	-0.4	-0.8	1.2	0.1	0.1	-0.2
Pack years of smoking	0.2	0.2	1.8	-0.2	0.1	-0.2	-0.4	-0.3	-0.3	-0.3	0.6	-1.3	-0.0	0.0	-0.6
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.6	0.5	0.3	0.3	0.5	0.5	0.0	0.3	-0.6	-0.1	0.8	0.2	0.8
Schizophrenia (2014)	0.1	0.3	0.6	0.4	0.6	0.3	0.4	0.5	0.7	0.2	-0.5	-0.8	-0.3	0.7	0.8
Blood Platelet Count	0.1	1.4	5.2	0.7	0.2	0.8	0.8	0.9	0.9	1.1	0.9	2.2	2.3	1.0	0.7
Blood Red Count	0.1	1.1	2.3	-1.1	-1.1	-1.1	-1.0	-1.3	-1.5	-0.9	-1.1	0.6	-0.5	-1.3	-0.5
Heel T-Score	0.1	1.1	8.1	-0.6	-0.5	-0.7	-0.7	-0.8	-0.8	-0.5	2.8	-0.3	-0.7	-0.5	-1.2
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.4	-0.3	-0.3	-0.2	0.3	-0.3	0.6	-0.1	-0.2	0.2	0.4	0.4	-0.1
Chronotype (morning person)	0.1	0.2	1.1	0.2	0.5	0.2	0.1	0.2	-0.3	0.1	0.6	-0.8	-0.2	0.1	1.0
Tanning	0.1	0.9	5.7	-0.6	-0.8	-0.5	-1.1	-0.4	-0.2	-0.5	-1.1	2.4	-0.9	-0.4	-0.8
Average weekly spirits intake	0.1	0.2	1.2	0.3	0.4	0.2	0.2	0.1	0.2	0.5	-0.1	-1.1	0.1	0.5	-0.1
Systolic blood pressure, automated reading	0.1	0.4	4.7	0.2	0.1	0.3	-0.4	0.1	0.1	0.2	-2.2	0.2	-0.0	0.1	-0.0
Trunk fat percentage	0.1	0.6	1.9	-0.6	-0.8	-0.6	-0.9	-0.6	-0.8	-0.6	-0.7	1.4	-0.6	-0.7	-0.2
Hand grip strength (right)	0.1	0.3	2.3	-0.0	-0.1	0.0	0.3	-0.1	-0.2	0.2	-0.5	0.2	0.7	0.1	1.5
Age when periods started (menarche)	0.1	0.1	0.4	-0.4	-0.3	-0.4	-0.2	-0.3	-0.1	-0.2	-0.6	0.5	-0.6	0.2	-0.3
Medication: Levothyroxine sodium	0.1	0.2	1.6	0.2	0.3	0.2	0.2	0.2	0.2	0.3	-0.0	-0.2	1.2	0.3	0.2
Impedance of leg (left)	0.1	0.6	2.5	0.4	0.7	0.5	0.7	0.2	-0.1	0.7	0.1	-1.6	1.1	0.7	0.9
Alcohol usually taken with meals	0.1	0.2	0.6	-0.0	0.1	-0.0	0.3	-0.1	0.4	0.2	-0.8	-0.3	-0.6	0.2	0.8
Had other major operations	0.1	0.1	0.6	-0.1	0.0	-0.0	-0.0	0.1	-0.4	-0.3	0.8	-0.4	-0.1	-0.1	-0.1
Forced vital capacity (FVC)	0.1	0.3	1.9	-0.0	0.1	-0.1	-0.2	-0.1	-0.7	-0.2	0.1	-1.4	-0.4	-0.1	1.0
Heart attack	0.1	0.2	0.9	-0.1	-0.0	-0.0	0.4	-0.2	0.3	0.2	-0.9	0.0	-0.6	0.1	0.4
Diabetes (self-reported)	0.1	0.1	0.4	-0.5	-0.4	-0.4	-0.2	-0.6	0.3	-0.3	0.1	0.5	0.2	0.1	-0.2
Medication: Simvastatin	0.1	0.1	0.7	0.1	-0.1	0.0	-0.1	0.2	-0.4	-0.0	-0.5	0.2	-0.6	-0.3	0.9
Neuroticism score	0.1	0.2	1.7	0.3	0.3	0.4	-0.4	0.3	0.4	0.3	0.5	-0.0	1.3	0.4	0.0
Arm fat percentage (right)	0.1	0.5	1.5	-0.4	-0.6	-0.4	-0.9	-0.4	-0.6	-0.5	-0.4	1.2	-1.1	-0.6	-0.7
Hip circumference	0.1	0.3	0.7	-0.3	-0.5	-0.4	-0.6	-0.3	-0.3	-0.4	-0.7	0.8	-0.8	-0.6	-0.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.9	-0.1	-0.1	-0.2	-0.1	-0.2	-0.6	-0.3	-0.4	-0.9	-0.6	-0.3	0.9
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.4	0.2	0.1	0.3	0.1	0.2	0.4	0.2	0.5	0.5	0.6	0.3	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.3	0.2	0.1	0.1	0.2	0.4	0.2	0.2	0.3	0.5	-0.5	0.1	0.3
Prospective memory result	0.1	0.1	0.8	0.3	0.2	0.3	0.0	0.3	0.5	0.3	0.0	0.2	0.5	0.2	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	0.9	-0.4	-0.4	-0.4	-0.5	-0.5	-0.9	-0.5	-0.7	0.0	-0.7	-0.4	1.0
Tense / ‘highly strung’	0.1	0.2	0.9	-0.1	-0.0	-0.0	-0.5	-0.0	0.4	-0.2	0.3	0.4	0.7	0.3	-1.0
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.3	-0.2	-0.1	-0.1	-0.4	-0.2	-0.2	0.0	-0.5	0.3	1.1	0.0	-0.4
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.4	0.5	0.5	0.5	0.4	0.5	0.3	0.4	-0.6	-0.1	-0.1	0.4	0.3
Forced vital capacity (FVC), Best measure	0.1	0.5	0.9	-0.4	-0.4	-0.5	-0.8	-0.5	-0.9	-0.6	-0.9	-0.6	-0.7	-0.4	1.0
Body fat percentage	0.1	0.4	1.9	-0.4	-0.7	-0.5	-0.9	-0.5	-0.6	-0.4	-0.7	1.4	-0.4	-0.5	-0.1
Leg fat percentage (right)	0.1	0.4	0.9	-0.4	-0.6	-0.5	-0.8	-0.5	-0.7	-0.3	-0.9	0.8	-0.4	-0.7	-0.3
Wheeze or whistling in the chest in last year	0.1	0.1	0.8	-0.0	-0.1	-0.0	-0.1	0.1	-0.2	0.1	0.4	0.5	-0.4	0.0	-0.9
Health satisfaction	0.1	0.1	0.5	0.2	0.3	0.3	-0.2	0.1	0.7	0.1	0.2	-0.6	-0.2	0.3	-0.3
Angina (self-reported)	0.1	0.2	0.7	-0.1	-0.5	-0.2	-0.1	-0.2	-0.5	0.2	0.6	0.8	0.3	-0.5	0.1
Pulse rate, automated reading	0.1	0.5	1.7	-0.6	-0.8	-0.6	-0.4	-0.6	-0.2	-0.5	0.4	0.7	-0.6	-0.7	-1.3
Overall health rating	0.1	0.1	0.7	0.2	-0.1	0.2	0.2	0.3	0.1	-0.0	0.7	0.9	0.4	-0.0	-0.3
Had major operations	0.1	0.1	0.3	-0.4	-0.2	-0.3	-0.2	-0.4	-0.4	-0.3	0.3	-0.3	-0.5	-0.2	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	0.4	0.4	0.4	0.1	0.3	0.2	0.5	0.1	-0.3	-0.4	0.3	-0.3
Arm fat percentage (left)	0.1	0.5	2.1	-0.4	-0.7	-0.5	-1.0	-0.4	-0.6	-0.5	-0.6	1.5	-0.8	-0.6	-0.5
Diabetes diagnosed by doctor	0.1	0.2	0.8	0.0	0.2	0.1	0.0	-0.1	0.9	0.2	0.4	-0.2	0.5	0.6	0.3
Guilty feelings	0.1	0.2	1.4	0.2	0.3	0.1	-0.2	0.1	-0.2	0.1	0.5	-1.2	0.2	-0.1	0.3
Commuting to job workplace: Public transport	0.1	0.2	0.8	0.1	0.2	0.1	-0.0	0.1	0.6	-0.1	-0.0	-0.3	-0.8	0.1	0.9
Eye problems/disorders: Glaucoma	0.1	0.2	0.8	0.0	0.3	0.1	-0.5	-0.2	0.3	0.0	-0.6	-0.9	0.0	0.4	-0.1
Age started oral contraceptive pill	0.1	0.1	0.5	-0.4	-0.2	-0.4	-0.1	-0.6	0.1	-0.1	-0.7	-0.3	-0.4	0.0	-0.4
Diastolic blood pressure, automated reading	0.1	0.5	1.9	0.6	0.6	0.7	-0.2	0.5	0.1	0.6	-1.4	-0.3	-0.5	0.4	1.2
Ever depressed for a whole week	0.1	0.2	0.3	0.5	0.4	0.5	0.5	0.5	-0.4	0.4	0.1	-0.2	0.6	0.0	-0.3
Cholesterol lowering medication	0.1	0.1	0.7	-0.1	-0.2	0.0	0.4	0.0	0.2	-0.1	0.4	0.6	-0.8	-0.1	-0.1
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.4	-0.1	-0.1	0.0	0.5	-0.2	0.3	0.3	-0.7	0.3	-0.6	0.0	0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.8	0.3	0.4	0.2	0.5	0.4	-0.3	0.0	-0.2	-0.9	-0.6	-0.3	-0.2
Cardiovascular Disease	0.0	0.1	0.5	0.1	0.2	0.1	-0.3	0.0	0.4	-0.1	-0.7	0.1	0.0	0.3	0.1
Lung FEV1/FVC ratio	0.0	0.1	0.8	-0.1	0.2	-0.1	0.4	-0.0	-0.0	0.0	0.0	-0.5	-0.9	-0.1	0.7
Hair Pigment	0.0	1.2	2.3	1.3	1.3	1.2	1.5	1.2	1.0	1.0	-0.3	-1.1	1.1	1.0	0.8
Hand grip strength (left)	0.0	0.1	0.8	-0.1	-0.0	-0.1	0.2	-0.2	-0.0	0.1	-0.4	-0.1	-0.1	0.1	0.9
Other serious medical condition/disability diagnosed by doctor	0.0	0.1	0.2	0.1	0.3	0.2	0.0	0.1	0.3	0.1	0.2	-0.4	0.3	0.2	0.3
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.3	0.1	0.0	0.1	0.4	0.1	-0.4	0.2	0.3	-0.3	-0.5	-0.0	0.1
Lung cancer (father)	0.0	0.0	0.3	0.1	0.1	0.1	0.3	0.1	0.2	-0.0	0.2	-0.5	-0.1	-0.1	0.0
Standing height	0.0	0.2	1.1	-0.3	-0.3	-0.4	-0.3	-0.3	-0.2	-0.5	-0.6	0.3	-0.4	-0.1	1.1
Comparative height size at age 10	0.0	0.2	1.1	-0.1	0.3	0.0	-0.6	-0.2	-0.4	-0.1	-0.3	-1.1	-0.7	0.2	0.6
Chest pain or discomfort	0.0	0.1	0.3	0.1	0.1	0.0	0.0	0.0	-0.4	0.1	-0.0	-0.4	-0.0	-0.1	-0.6

Hub : Genes

APBB1IP

Models

Trait associations