[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr10:28,113,533-29,671,014

Best TWAS P=3.36e-50 · Best GWAS P=5.29e-50 conditioned to 0.00189

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	WAC-AS1	0.39	0.46	lasso	5	0.45	1.1e-40	-14.5	-14.5	7.0e-48	0.94	0.14	0.86	FALSE
2	GTEx	Adipose Visceral Omentum	WAC-AS1	0.21	0.17	enet	16	0.18	2.0e-09	-14.5	-14.3	1.7e-46	0.91	0.06	0.94	FALSE
3	GTEx	Adrenal Gland	WAC-AS1	0.28	0.19	lasso	4	0.14	7.2e-06	-14.5	-14.4	6.3e-47	0.93	0.14	0.83	FALSE
4	GTEx	Artery Aorta	WAC-AS1	0.39	0.38	lasso	6	0.38	3.1e-22	-14.5	-14.5	1.1e-47	0.93	0.14	0.86	FALSE
5	GTEx	Artery Coronary	WAC-AS1	0.41	0.21	lasso	6	0.19	4.0e-07	-14.5	-14.9	3.4e-50	0.91	0.14	0.85	TRUE
6	GTEx	Artery Tibial	WAC	0.10	0.00	enet	32	0.00	5.6e-01	5.5	5.2	2.0e-07	-0.41	0.07	0.18	FALSE
7	GTEx	Artery Tibial	WAC-AS1	0.44	0.43	lasso	4	0.44	4.0e-37	-14.6	-14.4	3.8e-47	0.95	0.09	0.91	FALSE
8	GTEx	Brain Hippocampus	WAC-AS1	0.29	0.01	enet	10	-0.01	8.5e-01	-11.8	-12.5	5.5e-36	0.77	0.06	0.32	FALSE
9	GTEx	Brain Nucleus accumbens basal ganglia	WAC-AS1	0.38	0.07	enet	11	0.08	4.3e-03	-14.6	-12.6	1.6e-36	0.81	0.01	0.91	FALSE
10	GTEx	Breast Mammary Tissue	WAC-AS1	0.29	0.32	lasso	2	0.31	2.1e-16	-14.5	-14.5	9.4e-48	0.95	0.12	0.88	FALSE
11	GTEx	Breast Mammary Tissue (Female)	WAC-AS1	0.30	0.30	enet	13	0.33	1.7e-10	-14.5	-14.4	2.8e-47	0.94	0.12	0.88	FALSE
12	GTEx	Cells EBV-transformed lymphocytes	WAC-AS1	0.45	0.36	enet	12	0.41	1.1e-14	-14.5	-13.7	1.9e-42	0.85	0.14	0.86	FALSE
13	GTEx	Cells Transformed fibroblasts	WAC-AS1	0.58	0.62	lasso	12	0.64	9.7e-62	-14.5	-14.6	4.3e-48	0.94	0.15	0.85	FALSE
14	GTEx	Colon Sigmoid	WAC-AS1	0.36	0.23	lasso	9	0.22	2.6e-08	-14.6	-14.3	2.0e-46	0.92	0.10	0.90	FALSE
15	GTEx	Colon Transverse	WAC-AS1	0.36	0.17	enet	16	0.31	3.6e-15	-8.1	-12.7	4.8e-37	0.76	0.22	0.78	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	WAC-AS1	0.37	0.16	lasso	6	0.20	9.1e-08	-14.0	-14.4	1.0e-46	0.88	0.25	0.74	FALSE
17	GTEx	Esophagus Mucosa	WAC-AS1	0.52	0.44	lasso	16	0.51	1.2e-38	-14.5	-14.0	9.8e-45	0.87	0.14	0.86	FALSE
18	GTEx	Esophagus Muscularis	WAC-AS1	0.37	0.29	enet	32	0.38	5.5e-24	-14.5	-11.7	1.6e-31	0.78	0.15	0.85	FALSE
19	GTEx	Heart Atrial Appendage	WAC-AS1	0.18	0.12	enet	6	0.15	2.5e-07	-14.6	-14.1	2.3e-45	0.89	0.08	0.92	FALSE
20	GTEx	Heart Left Ventricle	WAC-AS1	0.39	0.08	lasso	8	0.20	1.3e-10	-8.1	-10.7	8.6e-27	0.63	0.69	0.30	FALSE
21	GTEx	Liver	WAC-AS1	0.37	0.34	lasso	3	0.34	3.1e-10	-14.5	-14.6	3.5e-48	0.97	0.11	0.89	FALSE
22	GTEx	Lung	WAC-AS1	0.32	0.13	enet	26	0.24	4.7e-18	-14.5	-13.5	1.3e-41	0.83	0.19	0.81	FALSE
23	GTEx	Muscle Skeletal	WAC-AS1	0.29	0.15	enet	26	0.22	8.7e-21	-8.1	-11.4	3.4e-30	0.71	0.58	0.42	FALSE
24	GTEx	Nerve Tibial	WAC-AS1	0.45	0.55	lasso	5	0.56	1.4e-46	-14.5	-14.6	4.3e-48	0.95	0.13	0.87	FALSE
25	GTEx	Pancreas	WAC-AS1	0.45	0.33	lasso	8	0.34	6.4e-15	-14.5	-14.6	1.4e-48	0.94	0.14	0.86	FALSE
26	GTEx	Skin Not Sun Exposed Suprapubic	WAC-AS1	0.48	0.48	enet	37	0.56	6.1e-37	-14.6	-14.0	2.3e-44	0.87	0.10	0.90	FALSE
27	GTEx	Skin Sun Exposed Lower leg	WAC-AS1	0.34	0.39	enet	21	0.45	7.7e-41	-14.6	-14.0	9.1e-45	0.90	0.09	0.91	FALSE
28	GTEx	Spleen	WAC-AS1	0.38	0.22	lasso	5	0.15	1.3e-04	4.5	-6.4	1.6e-10	0.33	0.42	0.15	FALSE
29	GTEx	Stomach	WAC-AS1	0.39	0.31	lasso	8	0.33	1.1e-16	-14.5	-14.4	8.9e-47	0.91	0.16	0.84	FALSE
30	GTEx	Testis	WAC-AS1	0.45	0.47	lasso	3	0.48	4.3e-24	-14.5	-14.6	4.7e-48	0.96	0.12	0.88	FALSE
31	GTEx	Thyroid	WAC-AS1	0.21	0.13	enet	12	0.20	1.6e-15	-14.5	-13.1	2.9e-39	0.79	0.16	0.84	FALSE
32	GTEx	Vagina	WAC-AS1	0.55	0.25	lasso	5	0.22	1.0e-05	-14.6	-14.1	2.9e-45	0.92	0.04	0.94	FALSE
33	GTEx	Whole Blood	WAC-AS1	0.19	0.07	lasso	7	0.05	1.2e-05	4.5	-5.2	2.1e-07	0.25	0.73	0.14	FALSE
34	ROSMAP	Brain Pre-frontal Cortex	BAMBI	0.07	0.05	lasso	3	0.04	2.8e-06	-9.9	-9.5	2.3e-21	0.51	0.94	0.03	FALSE
35	ROSMAP	Brain Pre-frontal Cortex	WAC	0.21	0.29	lasso	5	0.29	5.9e-37	-13.9	-13.9	5.5e-44	0.87	1.00	0.00	FALSE
36	ROSMAP	Brain Pre-frontal Cortex	WAC-AS1	0.39	0.35	bslmm	570	0.49	1.8e-72	-8.1	-11.1	9.7e-29	0.67	1.00	0.00	FALSE
37	YFS	Blood	WAC	0.06	0.08	bslmm	649	0.08	2.2e-24	-13.2	14.2	7.3e-46	-0.86	0.98	0.02	FALSE
38	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	WAC	0.11	0.04	blup	83	0.07	1.3e-03	-14.0	-12.2	2.7e-34	0.78	0.08	0.34	FALSE
39	The Cancer Genome Atlas	Prostate Adenocarcinoma	WAC	0.07	0.02	blup	83	0.06	8.7e-07	-6.6	-9.4	7.2e-21	0.66	0.56	0.24	FALSE
40	The Cancer Genome Atlas	Thyroid Carcinoma	WAC	0.06	0.04	lasso	3	0.03	4.2e-04	-13.9	-13.3	1.5e-40	0.88	0.10	0.58	FALSE