[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr10:110,937,872-112,588,355

Best TWAS P=1.55e-15 · Best GWAS P=1.09e-14 conditioned to 0.12

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	ADD3	0.06	0.03	enet	7	0.04	4.1e-03	-6.9	-7.0	2.0e-12	0.83	0.04	0.92	FALSE
2	GTEx	Artery Aorta	ADD3	0.12	0.10	lasso	3	0.11	9.4e-07	-7.7	-7.1	9.2e-13	0.98	0.01	0.99	FALSE
3	GTEx	Brain Cerebellar Hemisphere	ADD3	0.40	0.34	lasso	6	0.45	4.2e-13	-7.4	-8.0	1.5e-15	0.88	0.04	0.96	TRUE
4	GTEx	Brain Cerebellum	ADD3	0.36	0.31	lasso	11	0.33	1.4e-10	-7.4	-7.8	5.4e-15	0.84	0.05	0.95	FALSE
5	GTEx	Breast Mammary Tissue	ADD3	0.08	0.05	lasso	3	0.04	3.4e-03	-7.7	-7.7	1.1e-14	1.00	0.02	0.87	FALSE
6	GTEx	Breast Mammary Tissue (Female)	ADD3	0.07	0.02	lasso	1	0.09	1.3e-03	-7.4	-7.4	9.9e-14	0.77	0.04	0.47	FALSE
7	GTEx	Colon Sigmoid	ADD3	0.10	0.04	lasso	7	0.03	3.3e-02	-7.5	-7.5	8.8e-14	0.92	0.04	0.86	FALSE
8	GTEx	Heart Left Ventricle	ADD3	0.10	0.02	enet	17	0.03	1.2e-02	-6.9	-7.1	1.4e-12	0.76	0.03	0.97	FALSE
9	GTEx	Lung	ADD3	0.07	0.05	lasso	4	0.04	2.2e-04	-7.6	-7.1	1.2e-12	0.77	0.02	0.97	FALSE
10	GTEx	Nerve Tibial	ADD3	0.08	0.07	lasso	3	0.04	4.3e-04	-7.7	-7.7	1.5e-14	0.98	0.01	0.99	FALSE
11	GTEx	Pituitary	ADD3	0.27	0.05	enet	9	0.08	4.0e-03	-6.6	-7.5	5.4e-14	0.93	0.04	0.90	FALSE
12	GTEx	Spleen	XPNPEP1	0.25	0.04	lasso	5	0.05	2.4e-02	-6.6	-6.0	1.5e-09	0.72	0.05	0.35	FALSE
13	GTEx	Spleen	ADD3	0.36	0.27	lasso	5	0.28	7.2e-08	-7.7	-7.7	1.0e-14	0.91	0.02	0.98	FALSE
14	GTEx	Thyroid	ADD3	0.06	0.00	enet	4	0.01	1.2e-01	-7.7	-7.9	3.6e-15	0.96	0.01	0.92	FALSE
15	METSIM	Adipose	XPNPEP1	0.05	0.01	blup	321	0.03	3.4e-05	-7.6	-5.5	4.0e-08	0.65	0.03	0.94	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	ADD3	0.04	0.03	lasso	4	0.02	2.1e-03	-6.8	-6.4	1.2e-10	0.79	0.08	0.90	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADD3	0.04	0.03	lasso	2	0.02	8.5e-04	-4.2	-5.3	1.0e-07	0.53	0.08	0.17	FALSE