Best TWAS P=2.05e-10 · Best GWAS P=1.51e-10 conditioned to 0.000527
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | TMEM180 | 0.25 | 0.23 | enet | 37 | 0.25 | 7.4e-14 | -3.8 | -5.3 | 1.0e-07 | -0.58 | 0.96 | 0.04 | FALSE |
| 2 | GTEx | Brain Cerebellum | TRIM8 | 0.34 | -0.01 | enet | 25 | 0.07 | 4.7e-03 | 5.5 | 6.4 | 2.0e-10 | 0.55 | 0.07 | 0.38 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | TRIM8 | 0.09 | 0.03 | enet | 25 | 0.06 | 3.7e-08 | 5.7 | 6.2 | 7.2e-10 | 0.84 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | ARL3 | 0.09 | 0.02 | blup | 57 | 0.05 | 1.8e-03 | -4.1 | 5.4 | 5.8e-08 | 0.36 | 0.03 | 0.08 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ACTR1A | 0.04 | 0.01 | blup | 51 | 0.02 | 7.1e-04 | -4.6 | -5.5 | 4.7e-08 | -0.55 | 0.01 | 0.76 | FALSE |