[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr1:154,225,344-155,726,290

Best TWAS P=5.64e-11 · Best GWAS P=4.58e-09 conditioned to 0.375

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere DCST2 0.45 0.10 lasso 6 0.16 6.6e-05 5.2 -5.9 3.8e-09 -0.78 0.02 0.93 FALSE
2 GTEx Brain Cerebellum DCST2 0.48 0.27 lasso 9 0.31 6.0e-10 5.3 -6.5 5.6e-11 -0.82 0.01 0.99 TRUE
3 GTEx Brain Nucleus accumbens basal ganglia DCST2 0.28 0.04 lasso 5 0.13 2.0e-04 -5.2 -5.8 5.0e-09 -0.73 0.02 0.85 FALSE
4 GTEx Brain Putamen basal ganglia DCST2 0.56 0.05 enet 11 0.10 2.8e-03 5.2 -5.8 8.2e-09 -0.91 0.01 0.96 FALSE
5 GTEx Breast Mammary Tissue (Male) RP11-307C12.11 0.21 -0.01 lasso 3 0.00 2.5e-01 5.1 -5.3 8.6e-08 -0.55 0.03 0.17 FALSE
6 GTEx Nerve Tibial PBXIP1 0.08 0.02 enet 9 0.04 5.3e-04 3.3 -5.3 1.2e-07 -0.59 0.25 0.68 FALSE
7 GTEx Skin Sun Exposed Lower leg ADAM15 0.14 0.09 lasso 4 0.08 6.1e-07 -5.2 5.2 2.0e-07 0.45 0.16 0.84 FALSE
8 GTEx Thyroid DCST2 0.16 0.12 lasso 2 0.11 6.4e-09 5.2 -5.7 1.3e-08 -0.84 0.11 0.89 FALSE
9 GTEx Whole Blood ADAM15 0.10 0.00 lasso 13 0.00 1.5e-01 5.7 5.3 1.2e-07 0.85 0.02 0.93 FALSE
10 METSIM Adipose DCST2 0.04 0.04 enet 12 0.04 4.3e-07 5.4 -6.1 8.6e-10 -0.77 0.02 0.98 FALSE
11 NTR Blood ZBTB7B 0.02 0.02 lasso 1 0.01 5.4e-05 -5.4 -5.4 7.7e-08 -0.73 0.05 0.94 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma LENEP 0.01 0.00 blup 37 0.01 1.6e-03 4.9 -5.8 6.9e-09 -0.60 0.02 0.32 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ZBTB7B 0.05 0.06 lasso 2 0.05 1.8e-06 -5.2 5.2 1.7e-07 0.49 0.13 0.82 FALSE