Best TWAS P=8.66e-10 · Best GWAS P=2.1e-12 conditioned to 0.000274
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | LIN7C | 0.08 | 0.06 | lasso | 1 | 0.04 | 0.00041 | 5.3 | 5.3 | 9.6e-08 | 0.69 | 0.37 | 0.57 | FALSE |
2 | NTR | Blood | LIN7C | 0.01 | 0.00 | lasso | 3 | 0.01 | 0.00218 | 6.5 | -6.1 | 8.7e-10 | -0.76 | 0.04 | 0.92 | TRUE |