[Hub]/) : Traits : Blood Eosinophil Count :

chr11:46,723,603-48,559,571

Best TWAS P=2.79e-16 · Best GWAS P=4.61e-17 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere RP11-750H9.5 0.17 0.25 lasso 6 0.21 3.5e-06 5.50 -5.5 3.7e-08 0.50 0.39 0.15 FALSE
2 GTEx Breast Mammary Tissue (Female) PSMC3 0.02 0.01 lasso 1 0.04 2.5e-02 -8.18 8.2 2.8e-16 -0.98 0.02 0.38 TRUE
3 GTEx Lung PSMC3 0.07 0.02 lasso 2 0.03 3.6e-03 -5.94 5.5 3.6e-08 -0.63 0.16 0.20 FALSE
4 GTEx Muscle Skeletal SLC39A13 0.05 0.01 lasso 3 0.01 8.5e-02 -5.94 7.6 3.8e-14 -0.83 0.02 0.79 FALSE
5 GTEx Skin Sun Exposed Lower leg PSMC3 0.20 0.05 lasso 7 0.10 1.2e-08 -8.18 6.4 1.9e-10 -0.79 0.03 0.97 FALSE
6 METSIM Adipose PSMC3 0.06 0.03 enet 28 0.04 2.3e-06 4.53 5.9 4.3e-09 -0.68 0.04 0.96 FALSE
7 ROSMAP Brain Pre-frontal Cortex CELF1 0.03 0.01 bslmm 289 0.01 2.9e-02 -5.73 -7.5 7.9e-14 0.92 0.01 0.95 FALSE
8 ROSMAP Brain Pre-frontal Cortex PSMC3 0.15 0.08 bslmm 285 0.10 5.1e-13 -6.00 5.9 4.6e-09 -0.74 0.03 0.97 FALSE
9 YFS Blood NUP160 0.02 0.01 blup 290 0.01 1.7e-04 3.56 5.4 8.4e-08 -0.58 0.17 0.73 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma KBTBD4 0.14 0.01 blup 13 0.02 1.6e-02 0.18 5.3 8.6e-08 -0.74 0.00 0.00 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma PSMC3 0.10 0.05 blup 39 0.08 3.7e-09 2.08 5.6 2.2e-08 -0.77 0.01 0.99 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SLC39A13 0.06 0.01 blup 58 0.04 9.3e-04 -5.22 5.4 6.5e-08 -0.54 0.03 0.30 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma PSMC3 0.02 0.02 blup 39 0.02 5.7e-03 2.08 5.3 1.2e-07 -0.75 0.02 0.41 FALSE