Best TWAS P=2.38e-61 · Best GWAS P=3.88e-94 conditioned to 5.9e-40
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | ACER3 | 0.13 | 0.00 | lasso | 3 | 0.00 | 2.4e-01 | 2.3 | 5.3 | 1.1e-07 | 0.06 | 0.07 | 0.08 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | LRRC32 | 0.21 | 0.00 | enet | 15 | 0.01 | 1.5e-01 | 16.7 | 16.5 | 2.4e-61 | 0.62 | 0.00 | 0.96 | TRUE |
| 3 | GTEx | Whole Blood | AP001189.4 | 0.21 | 0.08 | enet | 9 | 0.10 | 8.2e-10 | 7.2 | 5.5 | 2.9e-08 | 0.05 | 1.00 | 0.00 | FALSE |
| 4 | YFS | Blood | LRRC32 | 0.02 | 0.00 | bslmm | 481 | 0.00 | 9.1e-02 | 4.6 | -8.5 | 2.5e-17 | -0.55 | 0.17 | 0.41 | FALSE |