[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr11:107,181,776-109,054,930

Best TWAS P=3.36e-35 · Best GWAS P=6.48e-35 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ATM	0.05	0.10	lasso	4	0.10	6.6e-12	-12.25	-12.3	9.7e-35	0.99	0.04	0.96	FALSE
2	CommonMind	Brain Pre-frontal Cortex	C11orf65	0.07	0.01	blup	371	0.03	1.9e-04	3.62	7.2	8.2e-13	-0.52	0.33	0.14	FALSE
3	GTEx	Adipose Visceral Omentum	KDELC2	0.14	0.11	lasso	3	0.08	4.5e-05	2.64	-5.5	4.2e-08	0.45	0.25	0.67	FALSE
4	GTEx	Artery Tibial	NPAT	0.06	0.06	lasso	4	0.05	5.6e-05	-11.91	11.9	1.1e-32	-0.98	0.10	0.88	FALSE
5	GTEx	Cells Transformed fibroblasts	ACAT1	0.18	0.15	lasso	8	0.21	1.7e-15	-7.79	-9.0	2.5e-19	0.85	0.08	0.92	FALSE
6	GTEx	Cells Transformed fibroblasts	ATM	0.07	0.06	lasso	2	0.05	2.2e-04	-12.25	-12.3	8.9e-35	0.99	0.03	0.96	FALSE
7	GTEx	Esophagus Mucosa	ACAT1	0.10	0.12	lasso	5	0.13	4.9e-09	4.72	-8.5	1.6e-17	0.80	0.09	0.91	FALSE
8	GTEx	Esophagus Muscularis	ATM	0.07	0.07	lasso	4	0.04	1.6e-03	-11.79	-11.8	5.9e-32	0.97	0.07	0.88	FALSE
9	GTEx	Esophagus Muscularis	RP11-144G7.2	0.06	0.04	lasso	2	0.03	3.5e-03	4.72	-7.2	4.9e-13	0.67	0.10	0.62	FALSE
10	GTEx	Heart Left Ventricle	KDELC2	0.07	0.05	lasso	4	0.06	3.8e-04	2.53	-6.2	5.0e-10	0.43	0.14	0.41	FALSE
11	GTEx	Muscle Skeletal	ACAT1	0.28	0.16	lasso	4	0.17	1.1e-16	-8.95	-8.1	6.2e-16	0.51	1.00	0.00	FALSE
12	GTEx	Muscle Skeletal	ATM	0.10	0.00	enet	24	0.01	1.4e-02	-8.95	-6.7	1.6e-11	0.53	0.10	0.13	FALSE
13	GTEx	Muscle Skeletal	CUL5	0.08	0.01	lasso	5	0.03	8.8e-04	-8.95	-7.8	4.4e-15	0.45	0.26	0.20	FALSE
14	GTEx	Muscle Skeletal	RP11-144G7.2	0.22	0.19	lasso	5	0.17	1.2e-16	-8.95	-8.6	1.2e-17	0.60	1.00	0.00	FALSE
15	GTEx	Nerve Tibial	ACAT1	0.05	0.02	lasso	5	0.00	9.0e-01	-12.25	-12.2	5.2e-34	0.99	0.04	0.93	FALSE
16	GTEx	Pituitary	ACAT1	0.16	0.09	lasso	10	0.08	5.3e-03	6.03	5.5	4.4e-08	-0.58	0.13	0.50	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	ACAT1	0.11	0.12	lasso	5	0.08	2.6e-05	4.72	-5.4	7.9e-08	0.58	0.75	0.10	FALSE
18	GTEx	Thyroid	NPAT	0.08	0.01	enet	32	0.04	8.1e-04	0.97	6.1	8.9e-10	-0.67	0.06	0.83	FALSE
19	NTR	Blood	ACAT1	0.03	0.02	bslmm	369	0.02	5.5e-08	4.69	7.5	5.2e-14	-0.49	0.96	0.03	FALSE
20	NTR	Blood	NPAT	0.02	0.01	blup	380	0.01	8.8e-05	-12.23	10.3	5.6e-25	-0.81	0.05	0.95	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	ATM	0.05	0.05	blup	370	0.05	5.8e-07	-12.25	-10.9	6.8e-28	0.92	0.04	0.96	FALSE
22	YFS	Blood	ACAT1	0.20	0.21	enet	32	0.34	1.3e-114	-11.79	-8.8	1.7e-18	0.82	0.34	0.66	FALSE
23	YFS	Blood	NPAT	0.06	0.08	lasso	8	0.09	3.2e-28	-12.23	12.0	2.1e-33	-0.93	0.06	0.94	FALSE
24	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C11orf65	0.02	0.01	blup	75	0.02	7.4e-03	-11.93	11.7	1.8e-31	-0.94	0.03	0.56	FALSE
25	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C11orf65	0.03	0.01	blup	75	0.02	4.3e-03	-12.28	12.3	1.2e-34	-0.95	0.03	0.76	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	ATM	0.05	0.03	blup	72	0.03	2.9e-04	-12.24	-12.4	3.4e-35	0.98	0.04	0.96	TRUE
27	The Cancer Genome Atlas	Stomach Adenocarcinoma	ATM	0.04	0.03	lasso	2	0.03	5.7e-03	-12.26	-12.3	1.5e-34	0.99	0.03	0.71	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	ATM	0.08	0.05	lasso	4	0.05	6.5e-06	-12.24	-12.1	1.2e-33	0.95	0.05	0.94	FALSE