TWAS hub - ACAT1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0530	0.0220	1.4e-03	0.032	0.028	0.030	0.029	0.029	8.2e-05	2.0e-04	1.4e-04	1.5e-04	1.5e-04
2	GTEx	Artery Aorta	0.0790	0.0350	3.6e-03	0.074	NA	0.095	NA	0.104	6.9e-05	NA	6.5e-06	NA	2.5e-06
3	GTEx	Artery Tibial	0.1222	0.0352	6.6e-08	0.085	NA	0.109	NA	0.113	3.7e-07	NA	7.4e-09	NA	3.9e-09
4	GTEx	Cells Transformed fibroblasts	0.1850	0.0470	7.3e-13	0.151	NA	0.206	NA	0.207	2.1e-11	NA	2.2e-15	NA	1.7e-15
5	GTEx	Esophagus Mucosa	0.1040	0.0310	6.3e-08	0.122	NA	0.094	NA	0.131	1.7e-08	NA	7.2e-07	NA	4.9e-09
6	GTEx	Muscle Skeletal	0.2765	0.0537	5.5e-13	0.155	NA	0.166	NA	0.173	5.5e-15	NA	4.8e-16	NA	1.1e-16
7	GTEx	Nerve Tibial	0.0513	0.0240	2.3e-03	0.022	NA	-0.004	NA	-0.004	9.6e-03	NA	9.2e-01	NA	9.0e-01
8	GTEx	Pituitary	0.1640	0.0650	1.2e-03	0.086	NA	0.066	NA	0.078	3.6e-03	NA	9.6e-03	NA	5.3e-03
9	GTEx	Skin Not Sun Exposed Suprapubic	0.1120	0.0440	2.6e-04	0.115	NA	0.059	NA	0.083	7.7e-07	NA	3.7e-04	NA	2.6e-05
10	GTEx	Skin Sun Exposed Lower leg	0.1340	0.0390	1.5e-08	0.149	NA	0.132	NA	0.141	2.5e-12	NA	5.0e-11	NA	1.0e-11
11	GTEx	Testis	0.1670	0.0620	3.2e-04	0.043	NA	0.068	NA	0.076	5.3e-03	NA	5.9e-04	NA	3.0e-04
12	GTEx	Thyroid	0.3180	0.0500	0.0e+00	0.336	NA	0.364	NA	0.357	1.6e-26	NA	5.0e-29	NA	2.2e-28
13	NTR	Blood	0.0334	0.0115	1.9e-06	0.017	0.023	0.020	0.023	0.018	2.9e-06	6.0e-08	2.5e-07	5.5e-08	9.9e-07
14	YFS	Blood	0.2022	0.0354	0.0e+00	0.212	0.319	0.336	0.327	0.332	1.6e-67	1.2e-107	1.3e-114	1.3e-110	5.1e-113
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0240	0.0136	1.6e-03	0.014	0.014	0.012	NA	0.012	1.0e-02	9.2e-03	1.3e-02	NA	1.4e-02
16	TCGA	Thyroid Carcinoma	0.1450	0.0470	0.0e+00	0.163	0.203	0.224	NA	0.217	1.3e-15	1.6e-19	1.5e-21	NA	7.2e-21

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Blood Eosinophil Count	5.4	41.3	148.8	-2.7	-1.1	-4.9	-9.0	-8.5	-8.1	-12.2	5.5	-5.4	-4.6	2.2	-4.5	7.5	-8.8	-2.0	-4.3
Blood Platelet Count	4.0	46.1	125.4	-4.2	-2.3	-7.9	-9.1	-9.6	-5.8	-11.2	7.8	-7.8	-7.0	5.1	-1.1	3.4	-9.4	-4.5	-1.0
Medication: Amlodipine	4.0	5.6	10.7	-1.8	-3.3	-3.1	-2.3	-2.5	-0.9	-2.1	3.1	-2.6	-2.8	2.1	1.6	-1.5	-2.7	-2.6	1.6
Blood Red Count	3.9	37.9	81.0	-4.3	-2.2	-8.4	-7.4	-7.8	-2.5	-8.9	9.0	-7.3	-6.6	5.8	2.2	-1.5	-7.5	-5.8	2.1
Ulcerative Colitis	3.6	5.3	9.2	1.9	2.6	2.9	2.4	1.8	-1.0	1.7	-3.0	2.1	1.8	-3.0	-2.2	2.3	2.4	2.6	-2.0
Falls in the last year	3.5	4.8	10.6	2.8	1.9	2.1	2.8	2.9	0.9	2.5	-2.2	2.4	2.3	-2.4	-0.4	-1.1	3.2	1.8	-0.5
Blood White Count	3.3	24.3	49.6	-3.0	-3.0	-6.5	-5.4	-6.4	-2.5	-6.7	7.0	-6.1	-5.4	4.8	1.6	-1.1	-6.2	-4.6	2.0
Number of incorrect matches in round	3.3	5.5	9.2	2.5	2.7	2.9	1.5	1.8	-2.0	1.3	-3.0	2.1	2.1	-2.5	-2.9	1.7	2.0	3.0	-2.4
Eye problems/disorders: Cataract	3.3	3.8	7.6	-1.9	-2.8	-1.8	-0.9	-1.1	2.1	-0.0	1.8	-1.7	-1.6	2.2	2.7	-1.9	-1.6	-2.5	2.5
Medication: Blood pressure	3.2	6.0	12.3	-1.4	-3.0	-3.5	-1.5	-1.9	1.5	-1.3	3.5	-2.4	-2.2	2.5	2.7	-3.0	-1.9	-2.9	2.5
Commuting to job workplace: Cycle	3.2	3.9	10.1	-2.2	-3.2	-2.3	-2.0	-1.8	0.6	-1.6	2.2	-1.7	-1.6	1.9	1.7	-0.5	-2.6	-2.4	1.5
Lung cancer (father)	3.0	3.5	7.6	-1.9	-2.4	-1.9	-0.8	-1.0	1.8	0.2	1.8	-1.6	-1.7	2.1	2.8	-2.3	-1.3	-2.4	2.3
Alzheimer’s Disease (in mother)	2.9	3.4	6.2	1.7	1.5	2.3	1.9	2.4	0.0	1.9	-2.0	2.3	2.4	-1.9	-1.3	-0.1	2.5	2.0	-1.1
Medication: Bendroflumethiazide	2.9	4.4	8.9	-1.1	-2.2	-3.0	-1.1	-2.0	0.2	-1.1	2.8	-2.6	-2.6	2.1	2.0	-2.5	-1.7	-2.4	1.9
Diverticular disease/diverticulitis (self-reported)	2.8	3.4	7.9	1.3	0.3	1.3	2.2	2.6	2.5	2.8	-1.2	1.9	1.7	-1.5	1.0	-2.4	2.7	0.7	0.9
Pulse wave reflection index	2.7	3.3	6.1	1.5	2.1	2.0	2.5	2.2	1.7	2.5	-1.8	1.9	2.0	-1.6	0.0	-0.5	2.4	1.5	-0.2
Medication for cholesterol	2.7	4.1	8.6	0.4	2.4	2.9	0.9	2.3	-0.1	1.6	-2.9	2.5	2.4	-2.2	-1.6	1.7	1.8	2.2	-1.7
Myopia	2.7	4.0	10.1	2.7	0.5	2.1	3.2	2.6	1.4	2.9	-2.1	2.0	1.7	-1.3	0.1	-1.1	2.9	1.1	0.2
Tinnitus: Yes, now most or all of the time	2.6	3.0	11.2	1.3	-0.6	-0.0	3.4	0.5	0.3	2.5	0.6	-0.8	-1.2	1.2	2.0	-3.3	1.4	-0.8	2.6
Rheumatoid Arthritis	2.5	3.5	20.4	0.6	-1.8	-1.1	1.2	0.6	2.5	1.6	1.3	-0.5	-0.2	1.4	2.4	-4.5	0.9	-1.4	2.6
Medication for hormone replacement therapy	2.3	2.5	5.4	-1.8	-0.9	-1.9	-1.9	-2.0	0.1	-1.6	1.2	-2.0	-2.1	2.1	0.7	0.7	-2.3	-1.3	0.5
High blood pressure (mother)	2.3	3.2	5.5	-2.0	-2.3	-2.3	-2.1	-1.7	-0.6	-1.9	2.3	-1.8	-1.6	1.4	1.0	-1.1	-2.3	-1.9	1.0
Supplements: Calcium	2.3	2.6	5.6	-1.6	-1.0	-1.9	-1.8	-1.9	-0.3	-2.2	1.7	-1.7	-1.7	1.9	0.8	0.5	-2.4	-1.7	0.8
Hearing aid user	2.2	2.5	5.4	-0.6	-1.0	-2.1	-0.3	-1.6	0.2	-0.7	2.3	-2.0	-2.1	1.5	1.8	-1.8	-0.9	-1.9	1.8
HDL Cholesterol	2.1	3.5	7.1	1.8	1.2	2.3	2.7	2.3	0.6	2.1	-2.2	2.2	2.0	-2.1	-0.6	0.5	2.6	1.6	-0.6
Bilateral oophorectomy (both ovaries removed)	2.1	2.4	9.7	-0.5	-2.1	-1.9	-0.3	0.1	2.0	0.4	1.6	-0.6	-0.6	0.8	2.4	-3.1	-0.2	-1.6	2.1
Medication: Cholesterol lowering	2.1	3.3	6.5	-1.9	-1.9	-1.7	-0.7	-1.5	0.9	0.1	1.6	-2.0	-2.4	2.0	2.5	-1.3	-1.6	-2.5	2.5
Medication: Atenolol	2.0	2.5	11.3	-0.9	-1.7	-1.2	-0.4	-0.1	3.4	0.6	1.0	-0.5	-0.8	1.5	2.5	-2.1	-0.6	-1.7	2.2
Pain all over the body in last month	2.0	2.2	4.2	-0.5	-0.8	-1.7	-1.3	-2.0	-0.8	-1.9	2.1	-1.8	-1.8	1.7	0.6	-0.1	-1.9	-1.4	0.9
Medication: Omeprazole	2.0	2.4	5.1	0.6	1.9	1.7	1.1	1.1	-2.3	0.7	-1.7	1.1	1.0	-2.0	-2.1	0.9	1.2	2.0	-2.0
Medication: Atorvastatin	2.0	2.5	5.5	-2.2	-1.1	-1.7	-1.9	-2.0	-0.3	-1.6	1.3	-1.8	-1.9	1.5	0.8	0.3	-2.3	-1.7	0.4
Vitamin and mineral supplements	1.9	2.6	6.8	-0.9	1.5	1.8	0.0	2.0	2.1	1.1	-1.9	2.5	2.6	-2.1	-0.5	0.5	1.1	1.5	-1.2
Multivitamins +/- minerals	1.8	2.3	5.8	0.7	-1.6	-1.8	-0.2	-2.0	-1.6	-1.0	1.8	-2.3	-2.4	1.7	0.8	-0.5	-1.2	-1.5	1.3
Medication: Simvastatin	1.8	2.6	7.5	-0.6	-2.3	-1.6	0.2	-0.6	0.9	0.5	1.8	-1.3	-1.4	1.4	2.4	-2.3	-0.5	-2.1	2.7
Alzheimer’s Disease (including proxy)	1.7	2.4	5.3	-0.3	1.1	2.1	0.7	2.0	0.4	1.4	-1.8	2.3	2.3	-1.9	-1.2	0.3	1.7	1.6	-1.4
Mean Putamen Volume	1.7	1.9	5.4	-0.9	-0.8	-1.4	-1.7	-2.0	-1.1	-2.3	1.2	-1.5	-1.2	0.9	-0.2	1.6	-2.0	-1.0	-0.2
Medication: Metformin	1.7	2.4	5.8	-0.8	-2.0	-1.2	0.2	-0.5	1.7	0.8	1.1	-1.3	-1.1	2.0	2.4	-2.1	-0.6	-2.0	2.4
Fed-up feelings	1.7	3.2	8.2	-0.0	-1.4	-1.9	-0.3	-2.2	-1.1	-0.9	2.1	-2.6	-2.6	2.9	1.2	-1.3	-1.6	-2.0	1.4
Mouth/teeth dental problems	1.7	2.6	7.7	-0.9	-0.9	-0.8	-2.3	-2.0	-2.3	-2.2	0.3	-1.4	-1.6	0.5	-1.0	2.8	-2.3	-0.5	-0.9
Medication: Aspirin	1.7	2.2	4.7	-1.4	-1.2	-1.7	-0.2	-0.8	1.3	-0.2	1.8	-1.4	-1.6	1.6	2.1	-1.6	-0.9	-2.0	2.2
Commuting to job workplace: Walk	1.7	1.8	5.9	-0.9	0.4	-0.6	-1.4	-1.8	-2.4	-2.0	0.7	-1.3	-1.4	0.6	-1.2	1.6	-1.7	-0.0	-1.2
Medication: Aspirin	1.7	2.2	3.7	-1.5	-1.2	-1.9	-0.6	-1.1	1.1	-0.6	1.8	-1.4	-1.6	1.5	1.9	-1.4	-1.3	-1.9	1.9
Had menopause	1.6	1.9	4.2	0.2	1.0	1.9	0.5	1.1	-0.3	0.4	-1.9	1.7	1.6	-1.9	-1.5	2.0	0.9	1.5	-1.6
Qualifications: None of the above	1.6	3.3	8.5	1.7	-1.3	-0.1	2.2	1.0	2.6	2.7	-0.2	0.1	0.0	1.2	2.7	-2.9	1.4	-1.0	2.9
Loud music exposure frequency	1.6	1.8	3.8	0.7	1.0	1.6	0.4	1.4	-0.7	0.6	-1.5	1.6	1.6	-1.9	-1.7	0.1	1.2	1.7	-1.7
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	5.1	1.8	1.7	1.6	1.0	1.3	-0.6	0.0	-1.6	1.8	2.3	-1.7	-2.1	1.2	1.6	2.1	-2.0
Pulse wave peak to peak time	1.6	1.9	6.5	-1.5	-1.4	-1.2	-2.5	-1.5	-0.6	-2.4	1.0	-0.7	-0.6	0.9	-0.4	1.7	-2.0	-0.9	-0.5
High cholesterol (Self-reported)	1.6	2.8	5.2	-1.8	-2.3	-1.9	-1.1	-1.5	0.5	-0.6	1.7	-1.7	-1.9	1.6	2.0	-1.0	-1.6	-2.2	1.9
Medication: Lisinopril	1.6	2.0	3.7	-0.2	-1.8	-1.1	0.1	-1.0	0.5	0.3	1.7	-1.7	-1.9	1.8	1.9	-1.6	-0.6	-1.9	1.9
Average weekly beer plus cider intake	1.6	2.3	4.9	-1.3	0.0	-1.4	-1.7	-2.2	-1.6	-1.9	1.1	-2.1	-2.1	1.7	-0.1	1.1	-1.9	-1.0	-0.1
Ever had prostate specific antigen (PSA) test	1.6	1.9	5.7	0.6	-0.5	-1.6	-0.4	-1.8	-1.4	-0.7	1.7	-2.2	-2.4	1.5	0.8	-0.7	-1.0	-1.1	1.3
Alcohol intake versus 10 years previously	1.5	2.3	4.6	-0.6	-1.2	-2.1	-0.5	-0.9	1.0	-0.2	1.8	-1.4	-1.5	1.9	2.1	-2.0	-0.7	-2.0	2.0
Noisy workplace	1.5	1.8	3.9	1.9	1.6	1.1	1.4	0.9	-2.0	0.0	-0.4	1.0	0.9	-1.7	-1.9	-0.1	1.4	1.7	-1.4
Glaucoma (self-reported)	1.5	1.7	4.4	0.6	-0.2	1.2	1.0	1.9	2.1	1.7	-0.9	1.9	2.1	-1.0	0.4	-1.0	1.5	0.7	0.2
Fractured/broken bones in last 5 years	1.5	1.9	4.8	-0.1	1.0	1.3	0.2	2.0	1.1	1.0	-1.7	2.1	2.2	-1.9	-0.9	-0.4	1.2	1.5	-1.2
Bipolar Disorder (2018)	1.4	2.3	7.4	0.7	1.2	1.0	-0.2	-0.4	-2.7	-0.9	-1.2	0.3	0.4	-1.2	-2.7	2.4	-0.2	1.7	-2.4
Bipolar Disorder (2011)	1.4	1.4	3.2	1.2	0.7	1.3	0.6	0.3	-1.8	0.3	-1.5	0.6	0.7	-1.1	-1.8	1.7	0.5	1.5	-1.5
Triglycerides	1.4	2.4	7.6	0.1	1.9	0.9	-1.1	0.1	-1.5	-1.5	-0.7	1.1	1.3	-1.3	-2.5	2.5	-0.3	1.7	-2.8
Pulse wave Arterial Stiffness index	1.4	1.7	5.7	1.3	1.3	1.1	2.4	1.4	0.7	2.3	-0.9	0.7	0.5	-0.8	0.4	-1.6	1.9	0.7	0.5
Age at last live birth	1.4	2.0	5.2	-0.6	0.0	-1.7	-1.5	-2.0	-1.2	-2.3	2.0	-1.9	-1.6	1.1	-0.2	0.4	-1.7	-0.9	-0.3
Average weekly champagne plus white wine intake	1.4	2.0	7.0	-1.8	0.2	-1.0	-2.2	-1.6	-1.2	-2.6	1.3	-0.9	-0.7	0.2	-1.1	1.5	-1.9	-0.3	-1.1
Ever taken oral contraceptive pill	1.4	1.6	4.7	0.7	2.2	1.0	0.0	-0.2	-1.4	-0.6	-0.9	0.3	0.7	-0.6	-2.0	2.0	0.0	1.7	-2.1
Systolic Blood Pressure	1.3	6.7	10.2	-3.0	-3.1	-3.1	-2.0	-2.0	1.2	-1.1	3.1	-2.6	-2.6	2.8	2.8	-2.5	-2.5	-3.2	2.6
Average weekly fortified wine intake	1.3	1.6	4.0	0.3	2.0	1.1	0.1	0.7	-1.1	-0.0	-1.1	0.9	1.2	-1.5	-1.9	0.8	0.8	1.9	-1.9
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.0	10.9	-0.4	-0.8	-1.3	0.6	-0.4	0.5	0.7	1.6	-1.2	-1.1	1.8	1.9	-3.3	-0.0	-1.4	2.0
Medication: Ventolin 100micrograms inhaler	1.3	1.7	4.3	0.7	-1.2	-1.5	0.3	-1.2	-0.6	-0.3	1.6	-1.7	-1.6	2.1	1.1	-1.7	-0.7	-1.2	1.6
Suffer from ‘nerves’	1.3	2.1	4.0	1.2	1.0	2.0	1.6	1.0	-1.6	1.1	-1.9	1.0	0.9	-1.6	-1.7	1.0	1.5	1.7	-1.5
Overall health rating	1.3	2.8	6.0	1.3	-2.1	-1.7	1.0	-1.2	-0.2	0.3	2.0	-2.0	-1.8	2.2	1.9	-2.5	-0.4	-1.7	2.3
Commuting to job workplace: Public transport	1.3	1.5	4.4	0.1	1.2	1.0	-0.3	0.5	-0.4	-0.9	-0.8	1.1	1.3	-1.8	-1.8	2.1	0.0	1.5	-1.9
Pain type(s) experienced in last month: Hip pain	1.3	1.6	4.4	-0.9	-1.1	-1.5	-2.1	-1.5	-0.9	-1.5	1.3	-1.5	-1.3	1.2	0.1	0.5	-1.8	-1.0	0.2
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.6	4.9	1.1	1.4	2.2	0.6	1.5	0.4	0.7	-2.0	2.0	2.1	-2.2	-1.7	1.4	1.2	2.1	-1.8
Medication for pain relief, constipation, heartburn	1.2	2.0	4.2	0.9	1.2	1.9	0.4	1.4	0.2	0.6	-2.1	1.9	1.9	-1.7	-1.3	1.4	1.2	1.6	-1.3
Medication: Blood pressure	1.2	2.1	4.1	-2.0	-1.5	-1.6	-1.5	-1.2	0.7	-0.5	1.6	-1.4	-1.8	1.4	1.6	-0.9	-1.6	-1.8	1.3
Medication: Ibuprofen	1.2	1.4	3.0	-0.0	-1.1	-1.5	-1.1	-1.7	-0.5	-1.4	1.4	-1.6	-1.5	1.4	0.3	0.7	-1.6	-1.1	0.2
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	5.8	-2.4	0.1	-1.0	-1.9	-1.2	-1.2	-1.4	0.6	-1.1	-1.0	0.7	-0.8	-0.2	-1.7	-0.4	-0.9
Average weekly red wine intake	1.2	1.8	3.3	1.1	1.2	1.6	0.8	1.3	-0.4	0.5	-1.3	1.6	1.7	-1.8	-1.5	0.9	1.2	1.8	-1.6
Mineral and other dietary supplements	1.2	1.6	3.8	-1.1	0.8	1.5	0.2	1.7	1.8	1.3	-1.6	1.9	2.0	-1.2	-0.3	-0.2	1.0	1.1	-0.8
Miserableness	1.2	2.2	4.5	-0.0	-1.2	-1.7	-0.5	-1.9	-1.8	-1.4	2.1	-2.0	-2.1	1.8	0.5	-0.1	-1.3	-1.4	0.8
Irritability	1.2	2.0	6.3	0.9	-0.8	-1.1	1.7	-0.4	0.3	1.1	1.3	-1.3	-1.7	1.6	2.0	-2.5	0.5	-1.3	2.2
Depressed Affect (Nagel 2018)	1.1	2.3	4.7	0.5	-0.9	-1.6	0.4	-1.5	-0.4	-0.1	2.0	-2.2	-2.1	2.1	1.7	-1.6	-0.9	-1.8	1.8
Number of treatments/medications taken	1.1	2.1	4.7	-0.2	-1.9	-1.7	0.1	-1.5	-1.0	-0.7	1.7	-2.0	-2.2	1.6	1.1	-1.2	-1.2	-1.6	1.4
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	3.3	0.3	-0.6	-1.6	-1.0	-1.8	-0.7	-1.4	1.4	-1.6	-1.6	1.3	0.2	0.4	-1.4	-1.0	0.2
Medication: Paracetamol	1.1	1.7	3.7	-1.0	-1.4	-1.6	-0.1	-1.0	0.1	0.1	1.5	-1.7	-1.6	1.8	1.5	-1.9	-0.9	-1.3	1.4
Intelligence (Savage-Jansen 2018)	1.0	3.2	7.4	0.6	2.5	1.8	0.2	1.6	-0.1	-0.4	-1.2	2.3	2.5	-2.7	-2.1	1.3	1.4	2.1	-2.4
Ulcerative Colitis (UC)	1.0	1.9	3.7	1.5	1.5	1.6	1.9	1.4	0.7	1.6	-1.6	1.5	1.2	-1.6	-0.6	1.1	1.7	1.2	-0.5
Lupus	1.0	1.5	6.5	-0.9	0.3	-1.0	-1.7	-1.1	-1.6	-2.5	1.4	-0.4	-0.3	-0.3	-1.2	1.1	-1.4	-0.0	-1.2
Heel T-Score	1.0	7.6	15.4	2.7	2.0	3.9	2.9	3.2	-0.5	3.0	-3.4	3.2	3.0	-2.8	-1.9	1.4	3.5	3.0	-1.2
Leg fat-free mass (left)	1.0	5.2	13.9	-1.7	-1.4	-3.5	-2.1	-2.3	0.8	-2.5	3.7	-2.4	-2.1	2.0	1.9	-2.3	-2.2	-2.6	1.3
Leg predicted mass (left)	1.0	5.0	13.5	-1.6	-1.4	-3.5	-2.1	-2.2	0.8	-2.5	3.7	-2.3	-2.0	1.9	1.8	-2.3	-2.2	-2.5	1.2
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	5.2	0.9	1.3	2.3	0.8	1.4	0.2	1.1	-2.1	1.6	1.8	-2.0	-1.5	0.9	1.3	2.0	-1.4
Qualifications: O levels/GCSEs or equivalent	1.0	1.5	4.3	0.7	2.0	0.9	0.3	0.1	-1.5	-0.8	-0.6	0.5	0.7	-1.1	-2.1	1.8	0.5	1.5	-2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.9	1.4	0.8	1.2	1.4	1.3	-0.4	0.5	-0.7	1.4	1.2	-1.7	-1.1	-0.3	1.5	1.4	-1.0
Age at first live birth	1.0	1.8	4.2	-1.2	0.2	-1.1	-2.0	-1.9	-1.2	-2.0	0.8	-1.5	-1.4	0.7	-0.6	1.8	-2.0	-0.4	-0.8
Angina (self-reported)	1.0	1.3	7.6	0.4	-0.7	0.4	1.2	1.1	2.8	1.4	-0.4	0.8	0.7	0.1	1.5	-1.2	0.7	-0.4	1.4
Medication: Allopurinol	1.0	1.3	3.7	-0.8	1.0	-0.2	-1.8	-0.8	-1.3	-1.9	0.1	-0.0	0.0	-0.6	-1.4	1.9	-1.1	0.5	-1.8
Medication: Seretide 50 evohaler	1.0	1.1	3.0	1.2	-0.4	-0.9	0.7	-1.1	-1.4	-0.3	1.0	-1.7	-1.7	1.6	0.5	-0.7	-0.4	-0.7	0.9
Smoking status: Previous	1.0	1.5	3.4	-0.3	-0.4	-1.7	-0.3	-1.1	0.4	-0.6	1.7	-1.6	-1.6	1.9	1.4	-0.9	-0.8	-1.4	1.5
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	6.5	1.1	0.1	-0.3	2.0	0.8	1.6	1.1	1.0	0.2	0.4	0.8	1.5	-2.6	1.3	-0.4	1.7
Breast cancer (self-reported)	1.0	1.2	4.6	-0.6	-0.8	0.3	1.1	1.3	2.2	1.4	-0.1	0.9	1.0	0.2	1.2	-1.5	1.0	-0.3	1.3
Smoking status: Current	1.0	1.5	2.9	1.3	0.8	1.4	1.0	1.0	-1.0	1.1	-1.7	1.1	1.2	-1.4	-1.4	0.2	1.3	1.7	-1.1
Risk taking	1.0	1.4	3.0	0.4	1.7	1.4	1.1	1.5	-0.9	1.5	-1.2	1.3	0.8	-1.1	-0.9	-0.5	1.5	1.3	-0.8
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	3.8	0.2	1.3	1.2	0.8	0.8	-1.9	0.6	-1.1	0.7	0.4	-1.5	-1.4	0.8	0.8	1.3	-1.3
Heart disease (siblings)	1.0	1.2	3.6	1.9	1.0	1.2	1.1	0.7	-1.1	0.6	-1.2	0.6	0.5	-1.3	-1.0	1.4	1.0	1.2	-0.7
Schizophrenia vs Biploar Disorder	0.9	1.2	3.1	0.2	-1.0	-1.0	0.4	-0.4	1.4	0.6	1.1	-1.0	-0.9	1.0	1.8	-1.6	0.1	-1.2	1.7
LDL Cholesterol	0.9	1.5	3.1	-0.1	1.8	1.1	1.3	1.6	0.9	1.2	-1.2	1.5	1.5	-1.1	-0.4	-1.0	1.6	1.1	-0.7
Angina	0.9	1.2	7.4	0.4	-0.8	0.3	1.0	0.9	2.7	1.2	-0.2	0.7	0.6	0.2	1.5	-1.1	0.5	-0.5	1.5
Current tobacco smoking	0.9	1.4	2.9	1.2	0.9	1.5	1.1	1.1	-0.6	1.3	-1.7	1.1	1.2	-1.3	-1.1	0.0	1.3	1.6	-0.9
Impedance of leg (left)	0.9	4.2	13.5	0.2	2.0	3.2	1.0	1.5	-1.0	1.3	-3.1	2.1	1.8	-1.7	-2.1	3.7	1.2	2.2	-1.7
Waist circumference	0.9	3.4	8.0	-1.5	-1.3	-2.5	-1.3	-1.3	1.6	-1.2	2.7	-1.6	-1.5	1.7	2.2	-2.8	-1.3	-2.4	1.7
Qualifications: A levels/AS levels or equivalent	0.9	2.0	4.8	1.9	1.7	1.3	1.2	0.5	-1.7	-0.4	-0.8	0.7	1.0	-1.4	-2.2	1.7	1.0	1.9	-1.6
Hair/balding pattern: Pattern 4	0.9	2.2	6.1	0.1	2.5	1.9	0.5	1.4	-0.1	0.5	-1.4	1.9	1.7	-1.8	-1.4	1.5	1.3	1.6	-1.5
High blood pressure (siblings)	0.9	1.2	2.7	-0.8	-0.5	-1.6	-1.6	-1.1	-0.1	-1.2	1.7	-1.0	-1.2	0.6	0.8	-0.8	-1.4	-1.3	0.7
Arm predicted mass (right)	0.9	4.5	11.4	-1.7	-1.5	-3.3	-1.9	-2.1	0.5	-2.1	3.4	-2.3	-1.9	1.9	1.7	-2.3	-2.1	-2.2	1.2
Comparative height size at age 10	0.9	5.2	8.6	-2.4	-0.8	-2.8	-2.4	-2.9	-0.2	-2.4	2.6	-2.7	-2.9	2.4	1.7	0.8	-2.9	-2.6	1.4
Whole body fat-free mass	0.9	5.1	13.8	-1.5	-1.1	-3.6	-1.9	-2.2	0.9	-2.4	3.7	-2.4	-2.1	2.0	1.9	-2.4	-2.1	-2.4	1.3
Mood swings	0.9	1.6	3.5	1.6	-0.7	-1.0	1.3	-1.3	-1.2	-0.0	1.6	-1.9	-1.8	1.8	0.9	-0.9	-0.3	-0.9	1.3
Qualifications: nursing, teaching	0.9	1.4	3.8	0.8	1.1	1.3	1.1	0.3	-2.0	0.1	-0.7	0.5	0.2	-1.7	-1.8	1.3	0.7	1.5	-1.5
Number of operations (self-reported)	0.9	1.3	6.3	-0.3	1.0	-0.2	1.1	1.2	2.1	1.3	0.1	0.5	0.4	0.0	1.3	-2.5	1.1	-0.1	1.2
Vascular/heart problems diagnosed by doctor	0.9	2.3	5.2	1.5	1.7	2.0	1.1	0.7	-1.6	0.3	-2.0	1.1	1.2	-1.1	-1.9	2.3	1.0	1.9	-1.6
Impedance of whole body	0.9	4.6	19.7	0.2	2.0	3.3	0.6	1.3	-1.0	0.8	-3.1	2.2	1.8	-2.0	-2.2	4.4	1.0	2.0	-2.0
Alzheimer’s Disease (in father)	0.8	0.9	5.3	-2.3	-0.2	0.4	-1.3	1.0	1.6	0.5	-0.5	1.2	1.0	-0.6	0.4	0.1	-0.2	-0.1	-0.2
Cardiovascular Disease	0.8	2.8	7.8	-0.9	-2.0	-2.4	-1.7	-1.6	0.4	-1.5	2.8	-1.5	-1.5	1.2	1.2	-2.0	-1.6	-2.0	0.9
Ever had hysterectomy (womb removed)	0.8	0.9	1.8	-0.2	-0.6	-1.2	-0.1	-0.8	-1.0	-0.2	1.1	-1.3	-1.3	1.0	0.8	-1.3	-0.5	-0.8	1.1
Systolic blood pressure, automated reading	0.8	2.2	5.0	-1.8	-1.7	-1.6	-0.7	-0.4	1.6	0.3	1.4	-1.0	-1.2	1.3	2.2	-2.1	-0.8	-1.9	2.0
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.1	0.8	0.4	0.9	0.4	0.9	-0.9	-0.0	-0.6	1.1	1.3	-1.4	-1.4	0.4	0.8	1.1	-1.3
High blood pressure	0.8	2.2	4.6	-1.2	-1.6	-2.1	-1.3	-1.1	0.7	-0.6	2.1	-1.4	-1.5	1.2	1.5	-2.1	-1.2	-1.7	1.2
Hearing difficulty/problems with background noise	0.8	1.3	4.1	1.9	2.0	0.8	1.6	0.6	-1.2	0.3	0.0	0.4	0.5	-1.2	-1.1	-0.7	1.4	1.4	-0.9
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	6.8	0.7	0.7	0.4	0.3	-0.6	-2.6	-0.9	-0.2	-0.2	-0.3	-0.5	-1.5	1.7	-0.1	0.7	-1.3
Impedance of arm (right)	0.8	3.6	15.9	0.5	1.9	2.9	0.8	1.3	-0.2	0.7	-2.8	2.0	1.6	-1.8	-1.8	4.0	1.1	1.6	-1.7
Impedance of arm (left)	0.8	3.6	16.1	0.1	1.7	3.0	0.5	1.3	-0.5	0.8	-2.9	2.0	1.6	-1.8	-1.8	4.0	0.9	1.7	-1.7
Medication: Paracetamol	0.8	1.3	3.6	-0.7	-0.8	-1.5	-0.2	-0.9	0.2	-0.0	1.5	-1.5	-1.3	1.5	1.3	-1.9	-0.6	-1.2	1.1
Number of full brothers	0.8	1.0	3.1	0.7	1.8	0.5	-0.4	0.5	-1.0	-0.2	-0.3	0.8	1.2	-0.9	-1.5	0.7	0.6	1.6	-1.7
Wheeze or whistling in the chest in last year	0.8	1.4	7.6	0.8	-0.4	-0.6	-0.5	-1.6	-2.8	-1.8	1.0	-1.3	-1.2	-0.1	-0.9	1.1	-1.1	-0.2	-0.6
Had major operations	0.8	0.9	2.7	0.6	0.5	0.6	1.4	1.3	1.1	1.6	-0.6	0.8	0.6	-0.4	0.7	-1.6	1.3	0.4	0.6
Family relationship satisfaction	0.8	1.0	3.0	-1.2	-1.0	-1.1	-1.3	-1.2	-0.6	-1.3	1.1	-1.0	-0.9	1.0	0.0	0.2	-1.7	-0.7	0.1
Handedness (chirality/laterality): Left-handed	0.8	1.0	3.9	0.4	0.2	-1.0	0.4	-0.4	0.7	0.2	1.4	-1.0	-0.8	1.4	1.3	-2.0	-0.0	-0.9	1.6
Whole body water mass	0.8	4.7	13.2	-1.3	-1.1	-3.5	-1.8	-2.1	0.9	-2.3	3.6	-2.3	-2.0	2.0	1.8	-2.4	-2.0	-2.4	1.3
Financial situation satisfaction	0.8	0.9	2.0	-0.2	-0.4	-1.3	-1.3	-1.4	-1.0	-1.4	1.1	-1.2	-1.0	0.7	-0.3	-0.5	-1.3	-0.6	-0.4
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.4	1.3	-1.1	-0.9	0.0	-1.3	-1.6	-0.8	1.0	-1.3	-1.4	1.1	0.2	0.2	-0.7	-0.7	0.7
Basal metabolic rate	0.8	4.4	12.1	-1.4	-1.1	-3.3	-1.9	-2.0	1.0	-2.3	3.5	-2.2	-1.8	1.8	1.8	-2.2	-2.0	-2.3	1.1
Arm fat-free mass (left)	0.8	4.1	11.5	-1.1	-1.3	-3.3	-1.5	-1.9	0.9	-2.0	3.4	-2.2	-1.8	1.8	1.8	-2.4	-1.8	-2.2	1.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.9	1.1	1.7	1.0	0.2	0.7	-1.3	0.3	-0.7	0.7	0.4	-0.9	-1.3	1.1	0.9	1.3	-1.2
Arm predicted mass (left)	0.8	3.9	11.1	-0.9	-1.1	-3.3	-1.4	-1.9	0.8	-2.1	3.3	-2.2	-1.7	1.7	1.7	-2.3	-1.7	-2.1	1.2
Type 2 Diabetes (T2D) (2018)	0.7	1.3	6.5	-1.4	-1.3	-0.6	-0.7	0.3	2.5	0.3	0.9	0.2	0.3	0.6	1.5	-1.5	-0.5	-1.3	1.1
Hearing difficulty/problems: Yes	0.7	1.1	4.3	1.4	2.1	0.6	0.7	0.4	-1.3	-0.1	-0.1	0.4	0.4	-1.3	-1.3	-0.3	1.1	1.3	-1.3
Stomach or abdominal pain in last month	0.7	0.9	3.4	0.3	1.8	0.2	-0.5	-0.2	-1.5	-1.0	0.1	0.2	0.1	-1.2	-1.4	1.1	0.0	1.1	-1.4
Trunk fat-free mass	0.7	4.2	11.9	-1.0	-0.7	-3.4	-1.5	-2.0	0.9	-2.0	3.5	-2.3	-1.9	1.9	1.8	-2.3	-1.7	-2.1	1.3
Medication: Lansoprazole	0.7	0.8	3.2	-0.2	-0.2	-1.0	-0.5	-0.3	1.8	-0.4	1.1	-0.4	-0.4	0.8	1.4	-0.8	-0.4	-1.0	1.1
Trunk predicted mass	0.7	4.0	11.5	-1.0	-0.7	-3.4	-1.4	-2.0	0.9	-2.0	3.4	-2.3	-1.9	1.9	1.8	-2.3	-1.7	-2.1	1.3
Blood clot in the leg (DVT)	0.7	0.9	2.5	0.9	1.6	0.9	0.1	0.6	-1.3	0.3	-0.6	0.7	0.3	-0.9	-1.3	1.0	0.8	1.2	-1.2
Arm fat-free mass (right)	0.7	3.7	10.1	-1.4	-1.3	-3.0	-1.7	-2.0	0.4	-2.0	3.2	-2.1	-1.8	1.7	1.5	-2.1	-1.9	-2.0	1.1
Mouth/teeth dental problems: Loose teeth	0.7	0.8	2.6	-0.2	1.0	0.3	0.5	1.2	1.6	0.8	-0.4	1.1	1.2	-0.9	0.1	-1.2	1.0	0.6	-0.5
Alcohol intake frequency.	0.7	1.6	5.1	0.2	-1.7	-0.8	0.8	-0.2	1.5	0.8	0.6	-0.7	-0.7	1.8	2.0	-1.7	-0.1	-1.5	2.3
Number of full sisters	0.7	0.9	2.0	0.5	0.5	-1.4	-0.3	-1.3	0.1	-1.1	1.4	-1.3	-1.1	1.1	0.9	-0.4	-0.5	-1.1	0.7
Hypertension (Self-reported)	0.7	2.1	4.4	-1.3	-1.7	-2.0	-1.7	-1.3	0.3	-1.1	2.1	-1.5	-1.5	1.1	1.1	-1.5	-1.5	-1.6	0.8
Leg fat-free mass (right)	0.7	3.8	11.0	-1.4	-1.1	-3.1	-1.9	-2.0	0.3	-2.4	3.3	-2.1	-1.8	1.4	1.3	-2.0	-2.0	-2.1	0.7
Ever had bowel cancer screening	0.7	0.8	2.2	-1.2	-0.1	-0.7	-0.4	-0.5	0.9	0.1	0.6	-0.8	-1.0	1.0	1.5	-0.3	-0.7	-1.2	1.4
Osteoporosis (self-reported)	0.7	0.9	3.0	0.5	0.4	0.6	1.6	1.3	0.5	1.4	-0.3	0.7	0.4	-0.4	0.6	-1.7	1.3	0.2	0.6
Medication: Gliclazide	0.7	0.8	3.4	0.3	-1.9	-0.4	0.6	0.1	1.2	0.4	0.6	-0.1	-0.1	0.8	1.4	-0.8	0.1	-1.1	1.5
Leg predicted mass (right)	0.7	3.9	11.1	-1.4	-1.1	-3.1	-2.0	-2.0	0.3	-2.4	3.3	-2.1	-1.9	1.4	1.3	-2.0	-2.0	-2.1	0.7
Wears glasses or contact lenses	0.7	0.7	4.2	-2.0	-0.5	-0.6	-1.5	-0.2	1.4	-0.2	-0.1	-0.2	-0.4	0.7	0.8	-0.2	-1.0	-0.7	0.3
Depression (Nagel 2018)	0.6	1.0	4.1	1.1	-0.5	0.0	0.9	0.8	1.6	1.4	-0.3	0.3	0.3	0.5	1.3	-2.0	0.7	-0.3	1.2
Neuroticism (2016)	0.6	0.9	2.1	0.7	-0.2	-1.3	-0.3	-1.2	-0.3	-0.9	1.5	-1.4	-1.1	1.0	0.6	-1.2	-0.7	-0.8	0.5
Waist Hip Ratio (WHR)	0.6	2.8	5.8	-2.2	-0.8	-2.1	-1.7	-1.6	0.6	-1.6	2.4	-1.6	-1.7	1.6	1.4	-1.3	-1.7	-2.1	1.3
Impedance of leg (right)	0.6	2.8	10.1	0.2	1.7	2.7	0.9	1.3	-0.1	1.3	-2.7	1.8	1.6	-1.1	-1.2	3.2	1.1	1.6	-1.0
Taking other prescription medications	0.6	1.0	2.9	0.5	-1.7	-1.0	0.9	-0.6	-0.1	-0.1	0.8	-1.0	-1.2	1.0	1.0	-1.3	-0.4	-1.2	1.3
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.5	-0.6	1.1	0.1	-1.2	-0.2	-1.1	-0.7	-0.3	0.1	0.2	-1.0	-1.2	0.8	-0.3	0.6	-1.2
Father’s age at death	0.6	0.8	2.0	1.0	-0.0	0.7	0.2	1.2	-0.2	0.4	-1.0	1.3	1.4	-1.2	-0.9	-0.4	0.9	0.9	-0.8
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	3.6	-0.9	-1.3	-1.6	-1.2	-1.9	-0.6	-1.7	1.8	-1.7	-1.6	1.5	0.7	1.1	-1.7	-1.6	0.7
Mouth/teeth dental problems: Dentures	0.6	1.0	2.1	0.4	0.4	1.1	0.7	1.4	1.0	1.3	-1.4	1.4	1.4	-0.9	-0.1	-0.4	1.2	0.8	-0.3
Asthma	0.6	1.1	6.3	1.9	-0.4	-0.6	0.4	-1.1	-2.5	-1.1	1.3	-1.2	-1.0	0.8	-0.7	-0.0	-0.2	-0.0	-0.0
Peak expiratory flow (PEF)	0.6	1.5	3.1	-0.9	-1.3	-1.6	-0.9	-1.4	0.2	-1.4	1.8	-1.3	-1.1	1.3	0.8	0.1	-1.5	-1.6	0.8
Chronic bronchitis/emphysema (mother)	0.6	0.6	2.2	0.8	-0.3	0.4	1.4	0.1	0.6	1.5	-0.1	-0.5	-0.6	0.9	1.0	-0.4	0.6	-0.4	1.3
Forced vital capacity (FVC), Best measure	0.6	2.1	4.4	-0.1	-1.1	-1.6	-0.5	-2.1	-0.9	-1.5	1.7	-2.0	-2.1	1.6	0.9	1.3	-1.5	-1.6	0.9
Shortness of breath walking on level ground	0.6	0.7	2.7	0.2	-1.6	-0.0	1.1	0.3	0.3	1.3	-0.2	-0.1	-0.2	0.6	0.8	-1.6	0.3	-0.4	1.2
Friendships satisfaction	0.6	0.8	2.1	-1.1	-0.7	-1.1	-1.4	-1.0	-0.0	-0.9	0.8	-0.9	-1.0	0.5	0.4	-0.5	-1.2	-0.9	0.3
Back pain experienced in last month	0.6	0.9	3.4	-0.6	-0.8	-0.2	0.9	0.6	1.1	1.2	0.4	0.1	-0.3	1.1	1.3	-1.9	0.5	-0.9	1.4
Alcohol drinker status: Previous	0.6	0.7	2.0	-0.3	-1.2	-0.2	0.4	-0.5	0.2	0.5	0.4	-0.9	-0.9	1.2	0.8	-1.4	-0.3	-0.9	1.2
Pack years of smoking	0.6	0.8	1.9	0.1	-0.3	-1.4	-0.6	-1.3	-0.1	-1.0	1.4	-1.4	-1.2	1.0	0.5	-0.8	-0.8	-0.8	0.3
Irritable Bowel Disease (IBD)	0.5	1.1	4.0	1.5	1.2	1.2	2.0	0.8	-0.0	1.6	-1.0	0.6	0.4	-1.0	-0.4	0.2	1.4	0.9	-0.2
Hand grip strength (left)	0.5	1.3	3.0	0.9	1.7	1.3	0.9	0.9	-0.1	0.4	-1.2	1.1	1.3	-1.4	-1.3	0.9	1.2	1.6	-1.3
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.4	1.1	-0.7	-0.8	0.1	-0.7	-0.1	-0.2	1.0	-0.9	-0.7	1.6	0.6	-1.2	-0.4	-0.7	0.9
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.6	0.9	0.1	0.9	1.3	1.1	0.2	1.1	-1.0	0.9	0.6	-0.5	-0.1	-0.4	1.2	0.4	0.0
Pack years adult smoking proportion	0.5	0.8	1.9	0.5	0.0	-1.4	-0.6	-1.3	-0.3	-1.2	1.4	-1.3	-1.0	0.9	0.2	-0.5	-0.8	-0.5	-0.0
Townsend deprivation index at recruitment	0.5	0.6	2.6	1.1	0.1	0.7	1.6	1.0	0.4	0.9	-0.5	0.9	0.7	-0.5	0.2	-0.8	1.2	0.2	0.1
Qualifications: CSEs or equivalent	0.5	0.6	2.2	-1.3	-1.5	-0.6	-1.0	-0.5	0.4	-0.4	0.7	-0.3	-0.2	0.7	0.4	-0.6	-1.0	-1.0	0.3
Past tobacco smoking	0.5	1.0	2.4	-0.4	0.4	1.5	0.2	1.0	0.1	0.7	-1.5	1.3	1.2	-1.4	-0.8	0.9	0.5	0.9	-1.1
Forced vital capacity (FVC)	0.5	1.9	3.5	-0.8	-1.1	-1.4	-0.9	-1.9	-0.8	-1.5	1.5	-1.8	-1.8	1.4	0.6	1.5	-1.6	-1.5	0.6
Allergy	0.5	1.1	4.0	-1.7	-0.6	-1.0	-0.8	-0.4	2.0	0.3	0.2	-0.7	-0.6	0.7	1.7	-0.7	-0.7	-1.1	1.2
Breastfed as a baby	0.5	0.6	1.6	0.1	0.8	1.1	0.1	0.4	-1.1	0.5	-1.3	0.6	0.6	-0.5	-1.1	0.7	0.3	0.9	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	5.1	1.5	-0.8	-0.5	0.2	-0.8	-2.2	-0.9	0.5	-0.8	-0.7	0.0	-0.9	0.0	-0.4	0.4	-0.5
Gout (self-reported)	0.5	0.8	3.3	-1.0	0.1	-0.3	-1.8	-0.6	-0.4	-1.4	0.1	-0.0	0.1	-0.0	-0.7	1.5	-1.1	0.1	-1.0
Exposure to tobacco smoke outside home	0.5	0.7	2.9	1.3	1.0	0.2	1.4	0.6	-0.5	1.0	0.0	0.0	-0.1	0.0	0.1	-1.7	1.4	0.4	0.2
Health satisfaction	0.5	0.6	4.3	0.4	-0.5	-0.7	0.4	-0.7	-2.1	-0.5	0.9	-1.0	-0.8	0.3	-0.5	-0.7	-0.3	-0.0	-0.1
Eye problems/disorders: None of the above	0.5	0.6	2.8	0.1	1.7	-0.3	-0.8	-0.6	-0.9	-1.1	-0.0	-0.3	-0.2	-0.2	-0.9	0.9	-0.2	0.4	-1.1
Migraine (self-reported)	0.5	0.6	1.3	0.5	0.7	0.9	0.7	0.9	-0.2	0.3	-0.5	1.0	1.0	-0.9	-1.0	-0.1	0.9	1.1	-0.9
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.5	-1.2	-1.0	-0.7	-1.0	-0.7	0.6	-0.9	0.7	-0.5	-0.6	0.0	0.5	0.5	-1.2	-0.7	0.2
Long-standing illness, disability or infirmity	0.5	0.7	1.3	0.5	-1.1	-1.1	0.0	-0.8	-0.2	-0.8	1.1	-1.0	-1.1	0.8	0.7	-0.9	-0.7	-1.1	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	1.8	-0.5	0.8	-0.0	-1.4	-0.2	-0.6	-1.2	0.0	0.3	0.5	-0.3	-1.0	0.7	-0.6	0.4	-1.4
Asthma (self-reported)	0.5	1.1	6.7	2.0	-0.4	-0.5	0.6	-0.9	-2.6	-0.9	1.1	-1.0	-0.8	0.6	-0.8	-0.2	-0.0	0.2	-0.2
Eye problems/disorders: Glaucoma	0.5	0.6	2.9	0.4	-0.2	0.7	0.6	1.0	1.7	1.0	-0.2	1.0	1.2	-0.3	0.5	-0.6	0.7	0.3	0.4
Age started oral contraceptive pill	0.5	0.6	1.4	0.9	0.7	0.7	0.4	0.6	0.2	-0.0	-0.7	0.8	1.1	-1.2	-0.7	1.1	0.8	0.7	-0.6
Bipolar Disorder or Schizophrenia	0.4	1.0	6.0	0.0	-0.1	-0.1	-0.7	-1.1	-2.5	-1.2	0.2	-0.7	-0.8	-0.5	-1.4	1.3	-1.0	0.3	-1.2
Neuroticism (Nagel 2018)	0.4	1.0	2.4	1.0	-0.3	-0.4	1.3	-0.6	0.4	0.8	0.9	-1.1	-1.1	1.4	1.5	-1.3	-0.0	-1.0	1.6
Schizophrenia (2018)	0.4	0.8	1.8	-0.6	-1.1	-1.0	-0.7	-1.1	-1.0	-0.7	1.2	-1.2	-1.3	0.4	0.3	-0.3	-1.1	-1.0	0.4
Reaction Time	0.4	0.7	2.5	0.7	0.4	0.6	-0.4	-0.2	-1.6	-0.8	-0.1	0.2	0.3	-0.9	-1.5	1.1	-0.0	0.8	-1.5
Fasting Glucose	0.4	0.5	1.9	1.4	0.3	0.6	0.7	0.8	0.1	1.2	-0.8	0.4	0.3	-0.4	0.1	-0.7	0.9	0.3	0.2
HbA1C	0.4	0.4	1.4	-0.0	1.2	0.3	-0.4	0.7	0.3	-0.1	-0.7	1.0	1.1	-0.5	-0.6	0.1	0.3	0.6	-0.7
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.4	0.8	-0.2	1.1	1.1	0.3	-1.2	0.5	-0.6	0.3	0.5	-0.4	-0.8	0.4	0.7	0.7	-0.5
Chronotype (morning person)	0.4	0.9	2.1	-0.4	-0.7	-1.2	-0.9	-1.3	-0.4	-1.5	1.3	-1.1	-0.9	0.7	0.3	0.3	-1.3	-1.1	0.2
Average weekly spirits intake	0.4	0.5	1.3	0.6	-0.6	0.5	1.0	1.1	0.8	1.2	-0.5	0.8	0.7	-0.6	0.5	-0.7	0.9	0.2	0.5
Medication: Co-codamol	0.4	0.4	1.7	0.1	-1.3	-0.1	1.0	-0.0	0.1	0.8	-0.1	-0.3	-0.3	0.2	0.8	-1.2	0.2	-0.7	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	4.0	1.1	-0.1	-0.1	0.6	0.4	0.6	0.7	0.2	0.1	0.3	0.2	0.5	-2.0	0.7	-0.0	0.5
Medication: Levothyroxine sodium	0.4	0.7	2.4	0.0	0.8	0.8	0.7	-0.0	-1.6	-0.1	-1.1	0.1	0.2	-0.5	-1.5	1.3	0.1	0.9	-1.2
Body mass index (BMI)	0.4	1.6	6.1	-0.8	-0.9	-1.8	-0.9	-0.6	1.3	-1.0	1.9	-0.9	-0.5	0.8	1.4	-2.5	-0.8	-1.3	0.8
Hair/balding pattern: Pattern 2	0.4	0.6	1.8	0.6	-0.7	-0.5	0.6	-0.3	1.1	0.4	0.3	-0.7	-0.6	0.8	1.3	-0.8	-0.2	-0.9	1.1
Had other major operations	0.4	0.4	3.2	-0.8	-0.3	-0.6	0.4	0.2	0.5	0.4	0.2	-0.3	-0.4	0.4	0.7	-1.8	0.0	-0.6	0.9
Financial difficulties in last 2 years	0.4	0.5	1.0	0.9	1.0	0.7	0.5	0.5	0.1	0.8	-0.9	0.5	0.7	-0.1	-0.5	-0.8	0.9	0.7	-0.6
Heart attack	0.4	0.6	2.9	-0.4	-0.1	0.0	0.7	0.2	1.7	0.7	-0.2	0.1	-0.0	0.5	1.4	-1.0	0.1	-0.8	1.1
Diabetes (self-reported)	0.4	0.6	1.5	-1.2	-1.1	-0.6	-1.2	-0.3	1.1	-0.6	0.7	-0.1	-0.0	0.7	0.7	0.1	-0.9	-1.0	0.5
Fluid intelligence score	0.4	0.8	2.2	-1.1	1.0	-0.1	-1.5	-0.2	0.9	-1.3	0.1	0.5	0.7	-0.8	-0.5	1.5	-0.7	0.2	-1.0
Weight	0.4	2.0	5.2	-1.4	-0.6	-2.1	-1.4	-1.1	1.4	-1.5	2.3	-1.1	-0.9	1.0	1.4	-1.7	-1.3	-1.6	0.7
Hip circumference	0.4	1.9	5.2	-1.2	-0.8	-2.0	-1.5	-1.3	0.9	-1.6	2.3	-1.2	-1.0	0.9	1.3	-1.3	-1.4	-1.6	0.7
Illnesses of mother	0.4	0.5	2.1	-0.6	0.7	0.7	0.3	0.7	0.3	0.7	-1.4	0.7	0.5	-0.6	-0.5	0.5	0.5	0.8	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	3.3	-0.2	-0.7	-1.2	-0.9	-1.8	-0.9	-1.7	1.4	-1.5	-1.3	1.1	0.2	1.4	-1.4	-1.1	0.3
Exposure to tobacco smoke at home	0.4	0.4	1.3	0.0	-1.0	-0.7	0.5	0.1	0.3	0.1	0.9	-0.3	-0.3	0.4	0.9	-1.1	0.2	-0.7	1.1
Tense / ‘highly strung’	0.4	0.6	3.3	1.3	0.1	0.4	1.8	-0.5	-1.2	0.7	0.1	-0.9	-1.0	0.3	0.2	0.0	0.5	-0.0	0.6
Birth weight of first child	0.4	0.7	2.1	-0.1	-0.1	-0.5	-1.0	-1.1	-1.3	-1.5	0.2	-0.7	-0.6	0.1	-0.8	0.9	-1.1	0.0	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.7	0.7	0.2	0.9	1.2	0.3	-1.3	0.0	-0.3	0.4	0.3	-0.5	-0.8	1.2	0.6	0.5	-0.4
Mean time to correctly identify matches	0.4	0.8	1.9	0.5	0.9	1.0	-0.0	0.3	-1.3	0.1	-1.0	0.6	0.4	-1.3	-1.3	1.2	0.5	1.1	-1.4
Knee pain experienced in last month	0.4	0.6	2.0	0.1	-0.4	0.8	0.9	1.1	0.5	1.4	-1.0	1.0	0.9	-0.3	-0.0	-1.0	0.8	0.5	-0.0
Illnesses of siblings: Diabetes	0.4	0.5	1.4	1.0	0.1	0.4	0.5	0.7	0.7	1.1	-0.1	0.5	0.7	0.1	0.4	-1.2	1.0	0.4	0.5
Mother’s age at death	0.4	0.5	1.7	0.0	-0.5	-0.3	-0.7	-0.5	-1.3	-1.2	0.5	-0.1	0.1	-0.4	-0.9	1.1	-0.4	0.1	-0.8
Unable to work because of sickness or disability	0.4	0.5	1.5	0.1	-0.5	-0.8	-0.0	-0.7	0.2	-0.1	0.8	-0.9	-0.9	1.2	0.7	-0.8	-0.4	-0.7	0.9
Ovarian Cancer	0.3	0.4	1.6	-1.1	-0.9	-0.6	-0.5	-0.2	0.4	0.1	0.4	-0.6	-0.7	0.3	0.5	-1.3	-0.5	-0.5	0.6
Coronary Artery Disease (CAD)	0.3	0.4	0.9	-0.3	0.7	0.6	0.6	0.9	0.8	0.7	-0.6	0.9	0.9	-0.1	-0.1	-0.5	0.6	0.4	-0.0
Crohns Disease (2012)	0.3	0.4	1.3	0.8	0.6	0.9	1.0	0.0	-1.2	0.6	-0.6	0.0	-0.2	-0.6	-0.7	0.1	0.7	0.6	-0.5
Allergy or Eczema	0.3	0.7	2.2	1.5	0.5	1.0	1.0	0.5	-0.9	0.1	-0.8	0.7	0.6	-0.6	-1.0	0.7	0.5	0.7	-1.0
Supplements: Zinc	0.3	0.3	1.3	1.2	0.1	0.4	0.1	-0.5	-0.9	-0.2	-0.6	-0.4	-0.5	0.6	-0.7	0.6	-0.2	0.4	-0.5
Diabetes (mother)	0.3	0.4	1.1	1.0	-0.1	0.3	0.6	0.9	1.0	0.7	-0.1	0.8	0.9	-0.2	0.4	-0.7	0.8	0.1	0.2
Serious illness, injury or assault to yourself	0.3	0.4	2.5	0.7	0.1	-0.2	-0.1	-0.7	-1.6	-0.8	0.1	-0.5	-0.6	0.2	-0.7	0.8	-0.4	0.2	-0.3
Hayfever, allergic rhinitis or eczema	0.3	0.7	2.3	0.8	0.7	0.7	0.3	-0.0	-1.5	-0.8	-0.1	0.4	0.4	-0.7	-1.4	1.1	0.0	0.7	-1.4
Sitting height	0.3	1.8	4.5	-1.0	0.1	-1.7	-1.6	-1.9	-0.9	-2.1	1.8	-1.6	-1.7	0.8	0.1	0.7	-1.6	-1.1	-0.1
Chronic bronchitis/emphysema (father)	0.3	0.4	1.0	-0.5	0.0	-0.6	-0.6	-0.9	-0.8	-0.7	0.6	-1.0	-0.9	0.7	0.1	0.1	-0.7	-0.4	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	2.0	1.4	0.5	-0.1	1.2	-0.1	-0.7	0.4	0.4	-0.4	-0.3	0.3	0.2	-1.2	0.7	0.1	0.5
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.9	0.5	0.2	-0.6	-0.4	-1.0	-0.1	-0.6	0.4	-0.7	-0.8	0.6	0.3	0.8	-0.8	-0.5	0.4
Medication: Ramipril	0.3	0.4	1.1	0.0	-0.4	-0.7	-0.3	-0.9	-0.3	-0.6	0.7	-0.9	-1.0	0.6	0.4	-0.1	-0.7	-0.6	0.3
Pulse rate	0.3	0.5	1.6	0.9	-0.3	0.5	1.3	0.8	0.0	1.2	-0.4	0.4	0.3	-0.2	0.3	-1.2	0.8	0.2	0.6
Arm fat mass (right)	0.3	1.0	2.4	-0.9	-0.2	-1.5	-1.2	-0.6	1.4	-1.2	1.6	-0.6	-0.3	0.5	1.0	-1.3	-0.9	-1.1	0.3
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.9	0.2	-0.3	-0.4	0.5	-0.2	-0.4	0.4	0.9	-0.6	-0.6	0.6	0.6	-0.9	0.4	-0.4	0.9
Headache pain in last month	0.3	0.6	1.8	-0.3	0.4	-0.0	-1.0	-0.1	-1.0	-1.0	0.2	0.3	0.4	-0.8	-1.2	0.8	-0.4	0.6	-1.4
Emphysema/chronic bronchitis	0.3	0.3	0.8	0.4	-0.0	0.2	0.8	0.5	0.7	0.9	-0.0	0.1	0.1	0.6	0.6	-0.9	0.4	-0.1	0.9
Neck or shoulder pain in last month	0.3	0.4	1.7	-0.1	-0.0	0.6	0.0	1.1	0.1	0.1	-0.4	1.1	1.3	-0.8	-0.5	-0.3	0.5	0.5	-0.4
Heart disease (mother)	0.3	0.4	1.7	1.3	0.4	-0.0	0.2	-0.7	-1.0	-0.8	0.6	-0.5	-0.4	0.2	-0.4	0.8	-0.1	0.0	-0.3
Leg fat mass (right)	0.3	1.3	3.3	-1.2	-0.6	-1.4	-1.0	-0.6	1.4	-0.7	1.7	-0.8	-0.5	0.9	1.4	-1.8	-0.8	-1.2	0.8
Supplements: Vitamin C	0.3	0.4	1.2	0.1	0.5	0.1	-0.8	-0.1	-0.5	-1.0	-0.3	0.3	0.3	-0.1	-1.1	1.0	-0.5	0.4	-1.1
Illnesses of father: Heart disease	0.3	0.4	1.1	0.3	0.3	0.6	0.4	0.9	0.1	0.5	-1.0	1.0	1.0	-0.9	-0.4	0.2	0.7	0.6	-0.6
Loneliness, isolation	0.3	0.4	2.1	1.4	0.5	0.1	1.0	0.0	-0.1	0.8	0.2	-0.3	-0.1	0.2	0.4	-1.4	0.7	0.1	0.5
Diabetes diagnosed by doctor	0.3	0.6	1.8	-1.3	-1.4	-0.6	-1.1	-0.5	0.5	-0.7	0.7	-0.3	-0.2	0.6	0.4	0.1	-1.1	-0.9	0.2
Illnesses of father: None of the above (group 1)	0.3	0.3	1.3	0.3	0.5	-0.2	-0.3	-0.9	-0.2	-0.9	0.4	-0.7	-0.4	0.5	-0.3	1.1	-0.7	0.1	-0.2
Arm fat mass (left)	0.3	1.3	2.7	-1.1	-0.5	-1.6	-1.3	-0.6	1.6	-1.1	1.6	-0.7	-0.4	0.6	1.3	-1.5	-0.9	-1.3	0.6
Pain experienced in last month	0.3	0.5	2.0	0.7	-0.2	0.4	1.3	0.4	0.6	1.4	-0.5	-0.1	-0.1	0.1	0.7	-0.7	0.8	0.0	0.8
Basal cell carcinoma (self-reported)	0.3	0.4	2.2	-0.7	-0.4	-0.9	-0.9	-0.1	1.5	-0.7	0.7	0.1	0.2	0.0	0.6	-0.4	-0.6	-0.5	0.3
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.2	-0.2	-0.1	0.0	0.7	0.2	1.5	0.5	-0.1	0.1	0.0	0.4	1.1	-0.9	0.2	-0.7	0.9
Leg fat mass (left)	0.3	1.0	2.9	-1.3	-0.5	-1.3	-1.0	-0.6	1.0	-0.8	1.6	-0.7	-0.5	0.6	1.1	-1.7	-0.8	-1.1	0.6
Worry (Nagel 2018)	0.2	0.3	1.8	1.0	-0.3	0.5	1.3	-0.6	-0.1	0.6	-0.1	-0.6	-0.5	0.5	0.4	0.2	-0.0	-0.3	0.7
Major Depression (MDD)	0.2	0.2	0.6	0.0	0.1	-0.7	-0.6	-0.4	0.4	-0.6	0.7	-0.4	-0.6	-0.1	0.4	-0.1	-0.6	-0.4	0.1
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.9	-0.1	1.4	-0.0	-0.8	0.1	1.1	-0.8	0.1	0.6	0.8	-0.7	-0.2	0.7	0.0	0.4	-0.7
Prostate Cancer	0.2	0.3	1.4	-0.7	-0.4	-0.2	-0.4	-0.3	-1.2	-0.5	0.1	-0.2	-0.4	-0.1	-0.7	0.2	-0.4	0.2	-0.9
Age at First Birth	0.2	0.3	0.8	0.1	0.5	-0.8	-0.2	-0.7	-0.8	-0.6	0.7	-0.8	-0.9	-0.1	-0.1	-0.1	-0.4	-0.4	-0.1
BMI	0.2	1.4	10.7	0.5	-0.4	-1.1	0.4	0.3	1.4	0.0	1.7	-0.2	0.1	0.3	1.5	-3.3	0.5	-0.9	1.1
Height	0.2	3.2	9.2	-1.4	0.3	-2.5	-2.0	-2.4	-0.5	-3.0	3.0	-2.0	-1.7	1.3	0.5	0.4	-2.2	-1.5	0.1
Respiratory disease	0.2	0.5	2.9	1.5	-0.4	-0.2	0.4	-0.2	-1.7	-0.2	0.5	-0.5	-0.4	0.4	-0.7	-0.6	0.2	0.4	-0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.0	-1.0	-0.4	-0.6	-0.3	0.0	0.6	-0.3	0.6	-0.2	-0.1	0.4	0.5	-0.4	-0.4	-0.3	0.4
Diabetes (father)	0.2	0.3	0.8	-0.3	0.5	0.8	0.1	0.8	-0.0	0.4	-0.7	0.9	0.7	-0.4	-0.4	0.0	0.6	0.6	-0.5
Severe depression (siblings)	0.2	0.2	1.3	0.8	0.1	-0.1	-0.3	-0.4	-1.1	-0.6	0.1	-0.3	-0.4	-0.2	-0.6	0.0	-0.3	0.3	-0.6
Hand grip strength (right)	0.2	0.5	1.2	0.7	0.6	0.9	1.1	0.6	0.2	0.7	-0.8	0.7	0.6	-0.8	-0.5	0.2	0.9	0.8	-0.4
Relative age voice broke	0.2	0.3	0.8	0.1	-0.2	-0.6	0.0	-0.7	-0.9	-0.5	0.7	-0.9	-0.8	0.5	-0.2	-0.4	-0.4	-0.3	0.0
Age when periods started (menarche)	0.2	0.4	0.9	0.7	1.0	0.6	0.8	0.4	-0.7	0.4	-0.6	0.2	0.3	-0.2	-0.8	0.2	0.7	0.8	-0.5
Supplements: Glucosamine	0.2	0.3	0.9	0.4	0.3	-0.7	0.5	-0.7	-0.5	-0.6	0.8	-1.0	-0.8	0.7	0.0	0.3	-0.1	-0.3	0.3
Trunk fat mass	0.2	1.0	3.0	-1.7	-0.2	-1.1	-1.4	-0.5	1.5	-1.1	1.2	-0.4	-0.3	0.4	1.1	-0.7	-1.0	-1.1	0.3
Nervous feelings	0.2	0.3	1.7	1.0	-0.2	0.9	1.3	-0.0	-0.3	0.8	-0.6	-0.2	-0.2	-0.2	-0.2	-0.1	0.5	0.2	0.1
Illnesses of siblings	0.2	0.2	0.6	-0.7	-0.4	0.5	0.7	0.4	0.6	0.8	-0.6	0.2	0.2	0.4	0.4	-0.3	0.4	0.0	0.2
Time employed in main current job	0.2	0.2	0.7	0.4	0.2	-0.2	0.9	-0.2	0.7	0.3	-0.1	-0.4	-0.4	0.6	0.6	-0.3	0.0	-0.5	0.7
Hair/balding pattern: Pattern 3	0.2	0.3	3.3	1.8	-0.3	0.1	0.8	0.1	-0.4	0.3	-0.3	-0.1	-0.0	-0.3	0.0	-0.3	0.3	0.2	0.2
Happiness	0.2	0.3	1.3	0.8	0.6	-0.5	-0.1	-0.2	-1.1	-0.5	0.6	-0.2	-0.0	-0.2	-0.7	-0.7	-0.0	0.5	-0.5
Prospective memory result	0.2	0.2	1.6	0.2	-0.3	-0.3	-0.8	-0.3	-1.3	-0.3	-0.0	-0.3	-0.5	-0.3	-0.6	-0.3	-0.3	0.0	-0.4
Standing height	0.2	1.6	4.0	-1.7	0.7	-1.3	-1.7	-1.6	0.1	-2.0	1.6	-1.0	-1.1	0.6	0.2	1.6	-1.6	-1.1	-0.3
Length of working week for main job	0.2	0.2	1.2	-0.4	-0.5	-0.2	-0.0	0.3	1.1	0.1	0.2	0.2	0.1	0.4	0.5	-0.7	-0.1	-0.4	0.6
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.0	-0.7	0.7	-0.5	-0.0	-0.0	0.1	-0.2	1.0	-0.2	-0.2	0.4	0.2	-0.9	0.2	-0.3	0.2
Birth weight	0.2	0.4	1.4	0.2	0.2	0.6	-0.4	0.2	-0.2	-0.3	-0.5	0.6	0.7	-0.7	-0.9	1.0	0.1	0.7	-1.2
Leg fat percentage (right)	0.2	0.6	2.0	-0.9	-0.5	-0.5	-0.3	-0.0	1.3	0.1	0.7	-0.2	-0.1	0.6	1.3	-1.4	-0.2	-0.8	0.8
Comparative body size at age 10	0.2	0.4	2.1	-0.8	0.2	-0.2	-1.4	-0.2	-0.2	-0.8	-0.1	0.4	0.4	-0.3	-0.5	1.2	-0.6	0.4	-1.0
Number of children fathered	0.2	0.2	0.8	0.1	0.6	-0.3	0.2	-0.1	0.9	0.5	0.2	-0.4	-0.4	0.5	0.8	-0.4	0.2	-0.1	0.6
Qualifications: College or University degree	0.2	0.7	1.7	1.0	0.5	1.0	1.3	0.5	-1.3	0.0	-0.3	0.5	0.4	-0.9	-1.0	0.9	0.9	0.9	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	1.6	0.4	-0.7	0.2	0.9	0.5	-0.1	0.6	0.1	-0.0	0.1	0.1	-0.0	-1.3	0.3	0.1	0.4
Whole body fat mass	0.2	0.8	1.9	-1.4	-0.2	-1.0	-1.2	-0.3	1.4	-0.8	1.2	-0.3	-0.2	0.3	1.0	-1.1	-0.7	-0.9	0.3
Pulse rate, automated reading	0.2	0.5	2.4	-0.1	-0.4	0.6	0.7	1.0	0.4	1.5	-0.6	0.5	0.3	-0.1	0.7	-1.2	0.8	-0.0	0.9
Chest pain or discomfort	0.2	0.2	0.9	0.4	1.0	0.3	0.6	0.4	-0.0	0.9	-0.0	0.1	0.1	-0.3	0.2	-0.6	0.8	0.3	0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.6	-0.8	0.4	0.7	-0.4	0.5	-0.4	0.1	-0.5	0.6	0.6	-0.3	-0.7	0.6	0.3	0.5	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.3	-0.3	0.8	0.4	-0.2	0.1	0.1	-0.6	-0.3	0.6	0.7	-0.6	-0.9	1.2	-0.3	0.7	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.5	0.1	-0.6	-0.4	0.4	-0.5	-0.3	0.1	0.5	-0.7	-0.5	0.5	0.6	-0.2	-0.1	-0.5	0.7
Osteoarthritis (self-reported)	0.2	0.3	0.8	0.0	0.2	0.5	0.6	0.8	0.5	0.9	-0.9	0.7	0.6	-0.3	0.0	-0.5	0.7	0.3	0.2
Guilty feelings	0.2	0.4	1.6	1.3	0.9	0.4	1.0	0.1	-0.5	0.7	-0.1	-0.2	-0.2	-0.1	0.2	-0.4	0.8	0.3	0.4
Ever smoked	0.2	0.4	1.6	0.8	0.4	-0.9	-0.4	-0.8	-0.9	-1.2	1.1	-0.6	-0.4	0.3	-0.4	0.0	-0.3	-0.0	-0.1
Diastolic blood pressure, automated reading	0.2	0.6	4.0	-1.1	0.9	-0.9	-0.7	0.2	0.9	0.0	0.9	-0.1	-0.1	-0.0	0.7	-2.0	0.1	-0.4	0.3
Cholesterol lowering medication	0.2	0.3	1.9	1.4	-0.8	-0.3	1.0	0.0	-0.3	-0.2	0.6	-0.1	0.2	-0.1	0.1	-1.0	0.5	-0.1	0.5
Crohns Disease (2017)	0.1	0.3	1.3	0.8	-0.1	0.1	1.1	-0.2	-0.4	0.8	0.0	-0.5	-0.5	0.1	0.1	-1.0	0.5	0.0	0.3
Breast Cancer	0.1	0.3	1.6	-1.3	-0.7	-0.2	-0.8	0.1	0.4	-0.3	-0.1	0.3	0.1	0.3	0.3	0.2	-0.8	-0.2	0.1
Body Mass Index (BMI) (2010)	0.1	0.2	0.6	0.7	0.3	-0.1	0.6	-0.2	-0.5	0.4	0.0	-0.6	-0.6	-0.1	0.1	-0.7	0.4	0.1	0.2
Primary Biliary Cirrhosis	0.1	0.1	0.3	0.4	0.6	0.2	0.2	-0.1	-0.0	-0.2	-0.1	0.0	0.0	-0.0	-0.3	0.4	0.1	0.4	-0.4
Schizophrenia (2014)	0.1	0.2	1.0	0.6	-0.5	0.1	0.7	0.3	-0.6	0.7	0.2	0.0	-0.0	-0.7	0.1	-1.0	0.5	0.1	0.3
Smoking Status	0.1	0.1	0.4	0.7	0.4	-0.2	0.2	-0.3	-0.6	-0.0	-0.0	-0.4	-0.2	0.1	-0.5	-0.5	0.2	0.4	-0.3
Hypothyroidism (self reported)	0.1	0.2	0.7	0.0	-0.2	0.4	0.4	0.2	-0.2	-0.0	-0.6	0.3	0.4	-0.5	-0.7	0.3	0.0	0.4	-0.8
Lung FEV1/FVC ratio	0.1	0.6	2.2	-0.6	0.0	-0.3	-1.5	-0.8	-0.6	-1.1	-0.3	-0.1	0.3	0.0	-1.0	1.0	-1.1	0.2	-1.0
Lung FVC	0.1	0.6	1.8	1.3	-0.2	0.3	1.3	-0.0	-0.2	1.2	-0.4	-0.5	-0.7	0.5	0.9	1.0	0.7	-0.2	1.0
Neuroticism	0.1	0.3	0.6	0.4	-0.1	-0.2	0.6	-0.4	0.5	0.3	0.7	-0.6	-0.5	0.8	0.7	-0.8	-0.1	-0.6	0.5
Hair Pigment	0.1	2.2	7.1	-0.2	-0.2	0.4	2.2	1.4	1.9	2.6	-0.1	0.3	0.2	0.0	1.9	-2.7	1.8	-0.4	2.0
Tanning	0.1	1.1	3.8	0.2	0.7	0.3	-0.6	-0.5	-2.0	-1.3	-0.2	0.1	-0.0	-0.9	-1.8	1.6	-0.5	0.9	-1.6
Sensitivity / hurt feelings	0.1	0.1	1.0	-0.4	0.8	-0.0	0.3	0.1	0.2	-0.2	0.5	0.2	0.3	0.1	-0.1	-1.0	0.2	0.0	-0.0
Relative age of first facial hair	0.1	0.3	1.1	-0.2	0.8	0.3	-0.2	-0.1	-0.3	-0.3	-0.2	0.0	0.2	-0.6	-1.1	0.1	-0.1	0.7	-0.9
Trunk fat percentage	0.1	0.5	2.8	-1.7	-0.0	-0.3	-1.2	-0.1	1.4	-0.7	0.5	0.2	0.2	-0.1	0.7	-0.0	-0.7	-0.7	-0.0
Maternal smoking around birth	0.1	0.2	0.5	-0.5	-0.2	-0.4	-0.3	-0.2	0.7	0.2	0.5	-0.4	-0.5	0.5	0.7	-0.5	-0.4	-0.6	0.4
Alcohol usually taken with meals	0.1	0.1	0.4	0.4	-0.3	-0.1	0.6	-0.2	-0.3	0.4	0.3	-0.4	-0.3	0.4	0.2	-0.5	0.2	-0.1	0.5
Neuroticism score	0.1	0.2	0.9	0.6	0.6	0.3	0.6	-0.3	-1.0	-0.0	0.2	-0.3	-0.2	0.2	-0.5	-0.2	0.2	0.2	-0.3
Arm fat percentage (right)	0.1	0.4	2.2	-0.7	0.1	-0.7	-0.7	-0.0	1.5	-0.6	0.7	-0.1	0.1	0.1	0.9	-1.1	-0.3	-0.7	0.2
Worrier / anxious feelings	0.1	0.2	1.1	1.0	0.0	0.3	0.9	-0.5	-0.1	0.1	0.3	-0.5	-0.3	0.6	0.2	-0.0	-0.0	-0.3	0.6
Number of live births	0.1	0.1	0.3	0.1	0.5	0.1	0.1	0.4	-0.3	0.3	0.2	0.2	0.3	-0.1	0.1	-0.3	0.5	0.2	0.1
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.8	-0.0	0.9	-0.4	-0.1	-0.1	-0.7	-0.0	-0.0	-0.5	-0.5	0.5	-0.1	-0.2	-0.1	0.1	0.0
Depression (self-reported)	0.1	0.2	0.5	0.5	-0.7	-0.7	-0.5	-0.1	-0.2	-0.7	0.7	0.1	0.2	0.1	-0.2	-0.4	-0.1	-0.0	0.0
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.7	-0.0	-0.1	0.6	0.8	0.1	-0.5	0.2	-0.8	0.1	0.1	-0.3	-0.6	0.5	0.1	0.3	-0.6
Body fat percentage	0.1	0.4	1.9	-1.4	-0.1	-0.3	-0.9	0.1	1.4	-0.4	0.4	0.2	0.2	-0.0	0.8	-0.5	-0.4	-0.6	0.1
Worry too long after embarrassment	0.1	0.2	0.8	-0.5	0.8	-0.2	-0.4	-0.5	0.0	-0.9	0.4	-0.2	-0.1	0.1	-0.2	0.1	-0.4	-0.2	-0.4
Leg pain on walking	0.1	0.2	1.1	-0.2	-1.1	0.1	0.2	-0.1	-0.4	0.4	0.2	-0.3	-0.3	0.4	0.1	-0.5	-0.2	-0.4	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.7	-0.8	0.6	0.1	-0.2	0.1	0.5	0.3	-0.2	0.2	-0.2	-0.3	0.3	0.2	-0.2	-0.1	-0.0
Arm fat percentage (left)	0.1	0.5	2.1	-1.1	-0.2	-0.7	-1.0	-0.1	1.5	-0.6	0.7	-0.0	0.1	0.1	0.9	-1.0	-0.5	-0.7	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.6	0.8	-0.2	0.2	0.3	0.2	-0.6	-0.3	-0.0	0.3	0.4	-0.3	-0.3	1.3	0.2	0.2	-0.2
Number of self-reported non-cancer illnesses	0.1	0.2	0.9	0.6	-0.2	-0.1	0.9	0.1	-0.6	0.2	0.3	-0.2	-0.4	-0.2	-0.1	-0.9	0.3	-0.0	0.1
Illnesses of father: High blood pressure	0.1	0.2	0.6	0.4	-0.8	-0.2	-0.0	-0.3	-0.3	0.1	0.3	-0.4	-0.5	0.2	0.3	-0.6	-0.2	-0.6	0.5
Alcohol drinker status: Never	0.1	0.1	0.3	0.5	-0.3	0.4	0.5	0.4	-0.1	0.3	-0.3	0.4	0.1	-0.2	0.0	0.0	0.4	0.1	0.1
Leg fat percentage (left)	0.1	0.3	1.3	-0.9	-0.5	-0.4	-0.5	-0.1	0.6	-0.1	0.6	-0.2	-0.1	0.3	0.8	-1.1	-0.4	-0.6	0.4
Ever depressed for a whole week	0.1	0.1	0.4	0.6	0.7	0.0	0.0	-0.1	0.2	-0.4	0.1	0.1	0.0	-0.4	-0.0	0.3	0.1	0.1	-0.1

Hub : Genes

ACAT1

Models

Trait associations