[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr11:110,472,030-112,295,421

Best TWAS P=7.29e-12 · Best GWAS P=2.16e-12 conditioned to 0.0358

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta COLCA2 0.09 0.10 lasso 2 0.07 1.3e-04 5.4 5.4 8.2e-08 0.75 0.15 0.46 FALSE
2 GTEx Brain Putamen basal ganglia LAYN 0.24 0.12 lasso 7 0.13 6.2e-04 4.9 -5.8 7.4e-09 0.01 0.20 0.05 FALSE
3 GTEx Cells EBV-transformed lymphocytes COLCA2 0.23 0.11 enet 19 0.26 6.2e-09 -3.0 -5.4 7.6e-08 -0.63 0.10 0.84 FALSE
4 GTEx Esophagus Mucosa SIK2 0.13 0.03 lasso 4 0.02 2.2e-02 5.7 5.5 3.1e-08 -0.06 0.27 0.14 FALSE
5 GTEx Muscle Skeletal COLCA2 0.06 0.02 lasso 2 0.01 2.9e-02 6.8 6.8 7.3e-12 0.85 0.02 0.95 TRUE
6 NTR Blood SIK2 0.01 0.00 enet 9 0.01 1.3e-04 6.0 6.4 1.4e-10 0.33 0.15 0.12 FALSE
7 ROSMAP Brain Pre-frontal Cortex LAYN 0.19 0.23 enet 26 0.25 2.9e-32 4.7 -5.3 1.4e-07 0.02 1.00 0.00 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma LAYN 0.02 0.03 blup 33 0.03 3.7e-06 4.7 5.2 1.5e-07 -0.06 0.23 0.77 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma SIK2 0.04 0.01 blup 35 0.01 6.7e-03 6.1 6.3 3.7e-10 0.02 0.01 0.93 TRUE
10 The Cancer Genome Atlas Prostate Adenocarcinoma SIK2 0.05 0.06 lasso 1 0.05 2.6e-06 6.0 6.0 1.6e-09 -0.03 0.01 0.99 FALSE