[Hub]/) : Traits : Blood Eosinophil Count :

chr13:99,047,988-100,903,542

Best TWAS P=8.19e-38 · Best GWAS P=1e-34 conditioned to 3.33e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex UBAC2 0.09 0.06 lasso 3 0.04 1.5e-05 -11.52 11.7 1.9e-31 -0.59 0.69 0.31 TRUE
2 GTEx Brain Cortex DOCK9-AS2 0.25 0.08 lasso 6 0.05 2.2e-02 1.23 -5.2 1.8e-07 0.06 0.14 0.05 FALSE
3 GTEx Breast Mammary Tissue (Male) DOCK9-AS2 0.21 0.00 lasso 5 -0.01 5.2e-01 -10.94 -9.7 3.3e-22 0.51 0.06 0.06 FALSE
4 GTEx Pituitary TM9SF2 0.30 0.01 enet 34 0.10 1.9e-03 -3.28 -5.5 5.0e-08 0.27 0.08 0.09 FALSE
5 GTEx Testis UBAC2 0.21 0.07 lasso 4 0.07 6.6e-04 -8.73 -9.4 5.9e-21 0.28 0.20 0.35 FALSE
6 NTR Blood TM9SF2 0.03 0.02 enet 20 0.02 2.0e-06 -6.72 5.5 3.7e-08 0.07 0.80 0.01 TRUE
7 YFS Blood UBAC2 0.06 0.03 bslmm 612 0.05 2.1e-15 3.07 -7.1 1.3e-12 0.56 0.92 0.08 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma TM9SF2 0.02 0.00 blup 93 0.01 4.6e-04 -5.35 -6.7 1.7e-11 0.20 0.03 0.29 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma UBAC2 0.05 0.00 blup 118 0.02 2.8e-04 -0.79 -12.9 8.2e-38 0.49 0.13 0.27 TRUE
10 The Cancer Genome Atlas Colon Adenocarcinoma TM9SF2 0.23 0.01 blup 93 0.08 3.7e-05 -6.17 -5.2 2.0e-07 0.13 0.03 0.05 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma TM9SF2 0.04 0.03 blup 93 0.02 1.9e-03 -5.35 -5.2 1.6e-07 0.00 0.42 0.10 FALSE