[Hub]/) : Traits : Blood Eosinophil Count :

chr13:113,970,662-115,106,996

Best TWAS P=4.73e-12 · Best GWAS P=6.27e-15 conditioned to 0.143

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CDC16 0.05 0.03 bslmm 208 0.04 2.4e-05 -3.6 -6.0 2.0e-09 0.45 0.87 0.05 FALSE
2 CommonMind Brain Pre-frontal Cortex RASA3 0.05 0.01 lasso 5 0.04 1.1e-05 -4.1 6.3 3.1e-10 -0.74 0.02 0.97 TRUE
3 GTEx Breast Mammary Tissue UPF3A 0.33 0.06 enet 18 0.18 9.7e-10 -3.7 -5.6 1.8e-08 0.45 0.27 0.72 FALSE
4 GTEx Breast Mammary Tissue (Female) UPF3A 0.32 0.16 lasso 13 0.17 1.2e-05 -3.7 -5.6 2.8e-08 0.36 0.75 0.18 TRUE
5 GTEx Small Intestine Terminal Ileum CDC16 0.16 0.04 lasso 9 0.03 6.1e-02 -3.6 -6.0 1.5e-09 0.45 0.09 0.10 FALSE
6 GTEx Testis UPF3A 0.24 0.12 enet 10 0.12 5.1e-06 -7.7 -6.9 4.7e-12 0.58 0.01 0.97 TRUE
7 GTEx Thyroid RASA3 0.26 0.28 enet 25 0.30 6.5e-23 6.0 6.2 7.2e-10 -0.55 0.98 0.02 FALSE
8 METSIM Adipose LINC00565 0.12 0.02 lasso 11 0.04 6.1e-07 -3.3 -6.4 2.0e-10 0.48 0.26 0.68 FALSE
9 YFS Blood UPF3A 0.21 0.17 enet 38 0.25 2.4e-82 -4.7 -5.2 2.5e-07 0.34 1.00 0.00 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RASA3 0.03 0.00 blup 89 0.00 2.1e-01 6.4 -6.1 1.2e-09 0.55 0.12 0.17 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma RASA3 0.08 0.06 lasso 2 0.06 7.1e-07 6.4 5.8 6.2e-09 -0.51 0.98 0.02 FALSE