[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr14:72,695,406-74,410,663

Best TWAS P=1.39e-15 · Best GWAS P=1.17e-10 conditioned to 0.831

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PSEN1	0.07	0.03	enet	7	0.02	5.1e-03	5.0	-6.1	1.1e-09	-0.48	0.10	0.53	FALSE
2	GTEx	Artery Aorta	RBM25	0.11	-0.01	enet	10	0.00	1.9e-01	3.6	6.1	1.0e-09	0.55	0.07	0.38	FALSE
3	GTEx	Artery Tibial	PSEN1	0.08	0.07	lasso	6	0.05	4.1e-05	5.0	-5.3	1.4e-07	-0.51	0.13	0.83	FALSE
4	GTEx	Brain Cerebellar Hemisphere	DCAF4	0.41	0.34	enet	19	0.36	4.0e-10	4.8	6.4	1.6e-10	0.69	0.02	0.97	FALSE
5	GTEx	Brain Cerebellum	DCAF4	0.38	0.17	lasso	6	0.34	7.5e-11	4.8	6.2	5.4e-10	0.70	0.05	0.95	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	RP11-109N23.6	0.22	0.12	lasso	8	0.16	5.1e-06	-3.2	-5.1	2.7e-07	-0.31	0.13	0.76	FALSE
7	GTEx	Nerve Tibial	PSEN1	0.10	0.04	lasso	5	0.04	9.3e-04	4.7	-5.3	1.5e-07	-0.41	0.34	0.20	FALSE
8	GTEx	Whole Blood	PSEN1	0.15	0.08	enet	15	0.14	1.2e-12	5.3	-7.0	2.4e-12	-0.25	0.19	0.80	FALSE
9	GTEx	Whole Blood	RP4-647C14.2	0.07	0.05	lasso	3	0.06	7.0e-06	4.8	-6.1	1.1e-09	-0.39	0.24	0.18	FALSE
10	METSIM	Adipose	PSEN1	0.05	0.03	lasso	3	0.03	9.9e-06	6.4	-6.9	3.7e-12	-0.91	0.00	1.00	FALSE
11	NTR	Blood	PSEN1	0.03	0.01	bslmm	423	0.01	3.6e-05	5.3	-8.0	1.4e-15	-0.45	0.45	0.49	TRUE
12	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DCAF4	0.04	0.00	blup	83	0.01	5.8e-02	-2.1	5.8	6.0e-09	0.46	0.03	0.16	TRUE
13	The Cancer Genome Atlas	Esophageal Carcinoma	DCAF4	0.12	0.03	enet	14	0.05	9.5e-03	4.8	5.8	6.6e-09	0.50	0.04	0.45	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DCAF4	0.04	0.02	blup	83	0.03	1.2e-04	6.0	5.5	4.7e-08	0.81	0.02	0.96	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSEN1	0.07	0.03	blup	58	0.05	5.2e-06	5.3	-7.1	1.2e-12	-0.28	0.01	0.97	FALSE
16	The Cancer Genome Atlas	Stomach Adenocarcinoma	DCAF4	0.07	0.02	blup	84	0.04	8.9e-04	6.4	6.6	4.2e-11	0.79	0.01	0.93	FALSE