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chr14:64,518,321-66,266,677

Best TWAS P=2.4e-13 · Best GWAS P=1.54e-13 conditioned to 0.114

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	MAX	0.15	0.16	lasso	2	0.16	1.2e-18	7.3	-7.3	2.4e-13	-0.93	0.01	0.99	TRUE
2	CommonMind	Brain Pre-frontal Cortex	SPTB	0.06	0.05	bslmm	528	0.05	9.5e-07	3.1	-5.2	2.4e-07	-0.34	0.87	0.04	FALSE
3	GTEx	Esophagus Gastroesophageal Junction	RAB15	0.20	0.13	lasso	13	0.16	2.4e-06	4.1	5.7	1.1e-08	0.44	0.20	0.76	FALSE
4	GTEx	Esophagus Muscularis	RAB15	0.35	0.06	enet	23	0.17	1.2e-10	3.6	5.9	3.4e-09	0.52	0.24	0.76	FALSE
5	GTEx	Muscle Skeletal	FNTB	0.05	0.02	lasso	6	0.01	5.8e-02	6.8	-7.1	1.7e-12	-0.92	0.03	0.94	FALSE
6	GTEx	Nerve Tibial	RAB15	0.35	0.15	enet	68	0.18	4.7e-13	7.1	5.4	8.7e-08	0.53	0.03	0.97	FALSE
7	GTEx	Pituitary	RAB15	0.32	0.03	enet	16	0.10	1.9e-03	7.1	6.8	9.6e-12	0.81	0.03	0.89	FALSE
8	METSIM	Adipose	RAB15	0.10	0.04	enet	22	0.08	3.8e-12	5.1	6.4	1.5e-10	0.58	0.14	0.86	FALSE
9	YFS	Blood	MAX	0.04	0.02	lasso	4	0.02	2.8e-06	6.6	-6.9	6.1e-12	-0.78	0.06	0.94	FALSE
10	YFS	Blood	RAB15	0.29	0.11	bslmm	485	0.22	8.5e-70	4.4	5.4	5.7e-08	0.42	1.00	0.00	FALSE
11	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FNTB	0.10	0.03	blup	107	0.07	7.9e-07	4.2	-6.4	1.5e-10	-0.59	0.68	0.22	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	FNTB	0.02	0.03	enet	8	0.03	2.0e-07	4.4	-5.8	6.8e-09	-0.54	0.87	0.12	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	RAB15	0.02	0.01	blup	49	0.02	6.7e-05	4.3	6.1	7.9e-10	0.59	0.08	0.85	FALSE
14	The Cancer Genome Atlas	Esophageal Carcinoma	FNTB	0.09	0.05	lasso	3	0.04	2.6e-02	4.9	-5.3	1.1e-07	-0.47	0.04	0.50	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FNTB	0.06	0.02	blup	106	0.04	3.7e-05	4.2	-6.0	1.7e-09	-0.54	0.19	0.26	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RAB15	0.03	0.00	blup	49	0.01	1.8e-02	7.1	6.6	4.9e-11	0.57	0.01	0.92	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FNTB	0.04	0.02	lasso	3	0.04	2.3e-05	4.2	-6.1	1.4e-09	-0.48	0.75	0.18	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RAB15	0.14	0.07	enet	15	0.09	5.5e-10	7.1	6.8	8.6e-12	0.67	0.00	1.00	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	RAB15	0.04	0.05	blup	49	0.06	2.5e-07	4.3	5.9	3.0e-09	0.53	0.33	0.65	FALSE
20	The Cancer Genome Atlas	Lung Adenocarcinoma	RAB15	0.04	0.01	enet	5	0.03	1.9e-04	6.0	5.8	8.2e-09	0.52	0.04	0.78	FALSE
21	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RAB15	0.11	0.01	enet	12	0.06	1.1e-04	4.4	6.0	2.0e-09	0.52	0.02	0.89	FALSE
22	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	FNTB	0.18	0.12	blup	107	0.18	6.5e-08	3.4	-5.4	8.6e-08	-0.50	0.88	0.10	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	FNTB	0.05	0.05	blup	107	0.06	3.6e-07	4.3	-5.5	3.8e-08	-0.43	0.99	0.00	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	RAB15	0.04	0.00	blup	49	0.01	6.9e-02	7.1	6.7	2.0e-11	0.70	0.00	0.97	FALSE
25	The Cancer Genome Atlas	Soft Tissue Sarcoma	FNTB	0.05	0.04	blup	107	0.03	6.5e-03	4.2	-5.6	1.8e-08	-0.45	0.24	0.08	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	FNTB	0.14	0.06	enet	18	0.14	1.4e-13	4.2	-6.9	6.6e-12	-0.62	0.32	0.68	FALSE
27	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	CHURC1	0.35	0.22	enet	14	0.24	2.9e-07	4.2	5.2	2.1e-07	0.36	0.02	0.80	FALSE