Best TWAS P=1.65e-09 · Best GWAS P=6.73e-12 conditioned to 0.000927
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | RASGRP1 | 0.37 | 0.44 | lasso | 5 | 0.42 | 3.6e-25 | 5.2 | 5.2 | 1.7e-07 | 0.77 | 0.97 | 0.03 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | RASGRP1 | 0.37 | 0.33 | lasso | 6 | 0.38 | 1.2e-32 | 5.2 | 5.1 | 2.7e-07 | 0.76 | 0.97 | 0.03 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RASGRP1 | 0.05 | 0.03 | lasso | 2 | 0.02 | 1.9e-03 | 6.5 | 6.0 | 1.7e-09 | 0.91 | 0.01 | 0.96 | TRUE |