[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr15:40,123,349-44,788,705

Best TWAS P=5.1e-14 · Best GWAS P=1.46e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NUSAP1	0.20	0.24	bslmm	311	0.24	4.6e-29	5.1	5.3	1.0e-07	0.08	0.48	0.52	FALSE
2	GTEx	Adipose Subcutaneous	ZSCAN29	0.27	0.11	enet	14	0.14	2.6e-11	7.1	-5.8	5.6e-09	-0.91	0.01	0.99	FALSE
3	GTEx	Artery Coronary	MIR1282	0.19	0.05	enet	9	0.07	2.8e-03	7.0	-6.6	3.3e-11	-0.97	0.02	0.84	FALSE
4	GTEx	Artery Tibial	TUBGCP4	0.09	0.07	lasso	5	0.06	1.5e-05	7.1	-7.0	2.1e-12	-0.91	0.01	0.98	FALSE
5	GTEx	Brain Caudate basal ganglia	NUSAP1	0.31	0.38	lasso	9	0.40	1.1e-12	5.3	5.6	2.5e-08	0.09	0.19	0.81	FALSE
6	GTEx	Brain Caudate basal ganglia	ZSCAN29	0.26	0.15	enet	19	0.14	5.8e-05	6.7	6.4	2.0e-10	0.85	0.02	0.96	FALSE
7	GTEx	Brain Cerebellar Hemisphere	EHD4	0.25	0.17	lasso	3	0.13	2.9e-04	-5.6	-6.0	1.6e-09	0.00	0.12	0.53	TRUE
8	GTEx	Brain Cerebellar Hemisphere	NUSAP1	0.24	0.31	lasso	6	0.22	2.0e-06	5.1	5.2	1.9e-07	0.10	0.21	0.76	FALSE
9	GTEx	Brain Cerebellar Hemisphere	NDUFAF1	0.20	0.23	lasso	6	0.22	2.2e-06	5.7	-5.5	3.6e-08	-0.08	0.16	0.80	FALSE
10	GTEx	Brain Cerebellum	EHD4	0.36	0.31	lasso	2	0.29	4.3e-09	-5.7	-5.1	3.1e-07	-0.02	0.08	0.92	FALSE
11	GTEx	Brain Cerebellum	OIP5	0.16	0.09	lasso	4	0.16	1.8e-05	5.1	5.6	1.8e-08	0.10	0.11	0.62	FALSE
12	GTEx	Brain Cerebellum	NUSAP1	0.22	0.23	enet	18	0.22	3.7e-07	5.3	5.3	8.7e-08	0.09	0.23	0.75	FALSE
13	GTEx	Brain Cerebellum	NDUFAF1	0.24	0.26	lasso	8	0.20	1.1e-06	5.7	-5.9	3.5e-09	-0.08	0.14	0.85	FALSE
14	GTEx	Brain Cerebellum	SPTBN5	0.29	0.30	lasso	3	0.31	7.9e-10	-5.7	-5.3	1.2e-07	-0.04	0.09	0.91	FALSE
15	GTEx	Brain Cerebellum	RP11-23P13.6	0.16	0.14	enet	9	0.11	3.6e-04	-5.7	-5.4	5.5e-08	-0.02	0.10	0.80	FALSE
16	GTEx	Brain Cortex	NUSAP1	0.43	0.25	enet	27	0.26	8.7e-08	5.3	5.1	2.8e-07	0.09	0.20	0.80	FALSE
17	GTEx	Brain Cortex	NDUFAF1	0.40	0.37	enet	22	0.36	7.0e-11	5.3	-5.7	1.2e-08	-0.04	0.30	0.70	FALSE
18	GTEx	Brain Frontal Cortex BA9	NUSAP1	0.39	0.42	enet	22	0.42	2.0e-12	5.3	5.6	2.6e-08	0.09	0.21	0.79	FALSE
19	GTEx	Brain Frontal Cortex BA9	NDUFAF1	0.55	0.37	lasso	8	0.40	1.6e-11	4.9	-5.2	2.0e-07	-0.07	0.24	0.76	FALSE
20	GTEx	Brain Hippocampus	NUSAP1	0.30	0.25	enet	14	0.26	1.0e-06	5.1	6.1	1.3e-09	0.10	0.11	0.78	FALSE
21	GTEx	Brain Hypothalamus	NUSAP1	0.26	0.36	lasso	4	0.27	5.6e-07	4.8	5.2	2.5e-07	0.07	0.18	0.79	FALSE
22	GTEx	Brain Hypothalamus	NDUFAF1	0.24	0.12	lasso	5	0.13	5.9e-04	4.7	-5.1	2.8e-07	-0.09	0.07	0.72	FALSE
23	GTEx	Brain Nucleus accumbens basal ganglia	NUSAP1	0.36	0.32	lasso	6	0.26	1.5e-07	4.9	5.7	1.5e-08	0.08	0.21	0.78	FALSE
24	GTEx	Brain Nucleus accumbens basal ganglia	NDUFAF1	0.12	0.11	lasso	6	0.10	9.7e-04	5.7	-5.8	5.3e-09	-0.05	0.15	0.60	FALSE
25	GTEx	Brain Nucleus accumbens basal ganglia	ZSCAN29	0.15	0.04	enet	19	0.07	6.1e-03	6.7	5.6	2.0e-08	0.80	0.04	0.53	FALSE
26	GTEx	Breast Mammary Tissue	ZSCAN29	0.11	0.16	lasso	5	0.12	9.4e-07	7.0	-6.7	2.3e-11	-0.98	0.01	0.99	FALSE
27	GTEx	Breast Mammary Tissue	OIP5-AS1	0.20	0.24	lasso	7	0.22	1.8e-11	5.0	5.5	3.0e-08	0.05	0.72	0.27	FALSE
28	GTEx	Breast Mammary Tissue (Male)	ZSCAN29	0.09	0.04	lasso	2	0.01	1.7e-01	7.0	-7.1	1.7e-12	-0.98	0.02	0.50	FALSE
29	GTEx	Breast Mammary Tissue (Male)	OIP5-AS1	0.26	0.10	enet	20	0.22	7.3e-06	5.5	6.6	3.7e-11	0.07	0.13	0.68	TRUE
30	GTEx	Breast Mammary Tissue (Female)	OIP5-AS1	0.28	0.31	lasso	3	0.29	3.0e-09	5.0	5.5	3.9e-08	0.05	0.15	0.85	FALSE
31	GTEx	Cells EBV-transformed lymphocytes	NDUFAF1	0.35	0.46	enet	14	0.51	3.1e-19	5.5	-5.7	1.1e-08	-0.08	0.12	0.88	FALSE
32	GTEx	Cells Transformed fibroblasts	NDUFAF1	0.26	0.15	lasso	8	0.20	2.8e-15	4.5	-5.5	4.1e-08	-0.07	0.17	0.83	FALSE
33	GTEx	Cells Transformed fibroblasts	ZSCAN29	0.11	0.07	lasso	6	0.06	3.2e-05	5.6	-5.7	1.6e-08	-0.84	0.04	0.95	FALSE
34	GTEx	Colon Sigmoid	NDUFAF1	0.15	0.06	lasso	4	0.06	5.2e-03	4.6	-5.2	2.5e-07	-0.07	0.10	0.74	FALSE
35	GTEx	Colon Transverse	ZSCAN29	0.06	0.04	lasso	4	0.04	6.1e-03	7.1	-6.1	1.0e-09	-0.92	0.04	0.88	FALSE
36	GTEx	Colon Transverse	OIP5-AS1	0.13	0.14	lasso	5	0.15	1.8e-07	4.9	5.2	2.5e-07	0.08	0.39	0.61	FALSE
37	GTEx	Esophagus Gastroesophageal Junction	NDUFAF1	0.19	0.13	lasso	5	0.16	1.8e-06	5.0	-6.3	2.4e-10	-0.06	0.10	0.89	FALSE
38	GTEx	Esophagus Gastroesophageal Junction	CATSPER2	0.28	0.05	lasso	9	0.12	3.7e-05	5.5	6.2	7.3e-10	0.76	0.16	0.20	FALSE
39	GTEx	Esophagus Mucosa	ADAL	0.26	0.10	lasso	7	0.14	6.8e-10	-2.5	5.6	2.2e-08	0.66	0.20	0.80	FALSE
40	GTEx	Esophagus Mucosa	LCMT2	0.24	0.18	lasso	2	0.16	6.3e-11	7.0	7.0	1.9e-12	0.99	0.01	0.99	FALSE
41	GTEx	Esophagus Mucosa	OIP5-AS1	0.20	0.22	lasso	6	0.20	1.7e-13	5.3	5.3	1.4e-07	0.06	0.30	0.70	FALSE
42	GTEx	Esophagus Muscularis	NDUFAF1	0.24	0.23	lasso	5	0.28	2.8e-17	5.0	-5.3	1.4e-07	-0.08	0.41	0.59	FALSE
43	GTEx	Esophagus Muscularis	TUBGCP4	0.12	0.09	enet	16	0.09	2.6e-06	7.0	-7.1	1.1e-12	-0.93	0.01	0.99	FALSE
44	GTEx	Esophagus Muscularis	ZSCAN29	0.14	0.11	enet	13	0.13	1.6e-08	7.1	-6.3	3.7e-10	-0.95	0.01	0.99	FALSE
45	GTEx	Heart Atrial Appendage	NDUFAF1	0.36	0.28	enet	24	0.34	9.5e-16	5.6	-5.6	1.7e-08	-0.06	0.10	0.90	FALSE
46	GTEx	Heart Left Ventricle	NDUFAF1	0.49	0.62	lasso	8	0.62	2.0e-41	5.7	-5.9	4.1e-09	-0.07	0.08	0.92	FALSE
47	GTEx	Heart Left Ventricle	ZSCAN29	0.11	0.06	lasso	3	0.05	1.5e-03	7.0	-7.5	5.1e-14	-0.98	0.02	0.86	TRUE
48	GTEx	Lung	NDUFAF1	0.34	0.18	enet	48	0.20	7.1e-15	5.3	5.6	1.9e-08	0.09	0.26	0.74	FALSE
49	GTEx	Lung	ZSCAN29	0.06	0.05	lasso	5	0.04	5.3e-04	7.1	-6.5	1.1e-10	-0.97	0.02	0.96	FALSE
50	GTEx	Muscle Skeletal	NDUFAF1	0.44	0.56	enet	31	0.60	3.0e-73	5.5	-5.6	2.5e-08	-0.08	0.15	0.85	FALSE
51	GTEx	Nerve Tibial	NDUFAF1	0.36	0.43	lasso	6	0.43	8.0e-33	5.3	5.5	4.1e-08	0.07	0.12	0.88	FALSE
52	GTEx	Nerve Tibial	TUBGCP4	0.07	0.08	lasso	1	0.06	3.4e-05	7.0	-7.0	2.6e-12	-0.99	0.02	0.97	FALSE
53	GTEx	Nerve Tibial	ZSCAN29	0.32	0.18	lasso	8	0.17	3.5e-12	7.1	-6.7	1.9e-11	-0.99	0.01	0.99	FALSE
54	GTEx	Pancreas	NDUFAF1	0.41	0.39	enet	20	0.42	2.7e-19	5.5	5.4	5.3e-08	0.08	0.12	0.88	FALSE
55	GTEx	Pancreas	ZSCAN29	0.11	0.04	lasso	3	0.03	1.9e-02	7.0	-6.9	4.6e-12	-0.99	0.02	0.90	FALSE
56	GTEx	Pituitary	NUSAP1	0.16	0.12	lasso	2	0.16	7.4e-05	5.3	5.7	1.2e-08	0.07	0.10	0.82	FALSE
57	GTEx	Prostate	NDUFAF1	0.30	0.12	lasso	2	0.14	2.7e-04	5.5	5.3	1.1e-07	0.11	0.15	0.48	FALSE
58	GTEx	Prostate	ZSCAN29	0.16	0.16	lasso	4	0.12	4.9e-04	7.0	-7.0	2.4e-12	-0.98	0.02	0.92	FALSE
59	GTEx	Skin Sun Exposed Lower leg	OIP5-AS1	0.13	0.17	lasso	3	0.23	5.0e-19	4.7	5.1	2.7e-07	0.08	0.79	0.21	FALSE
60	GTEx	Thyroid	C15orf57	0.19	0.26	lasso	5	0.27	1.7e-20	4.7	5.2	2.1e-07	0.03	0.02	0.97	FALSE
61	GTEx	Thyroid	NDUFAF1	0.25	0.21	lasso	6	0.22	9.3e-17	5.6	5.7	9.3e-09	0.08	0.12	0.88	FALSE
62	GTEx	Thyroid	RTF1	0.28	0.27	lasso	3	0.26	8.4e-20	-6.1	-6.2	5.6e-10	-0.04	0.00	1.00	FALSE
63	GTEx	Thyroid	ZSCAN29	0.17	0.16	enet	15	0.20	5.2e-15	4.1	-5.4	6.2e-08	-0.89	0.09	0.91	FALSE
64	GTEx	Whole Blood	NDUFAF1	0.25	0.07	lasso	6	0.12	6.4e-11	4.3	5.2	2.0e-07	0.09	0.30	0.69	FALSE
65	GTEx	Whole Blood	SERF2	0.05	0.03	lasso	3	0.02	3.8e-03	5.6	-5.7	1.5e-08	-0.87	0.04	0.84	FALSE
66	GTEx	Whole Blood	MIR1282	0.05	0.02	lasso	5	0.03	1.7e-03	5.6	-5.6	1.7e-08	-0.91	0.06	0.75	FALSE
67	METSIM	Adipose	ELL3	0.03	0.00	lasso	8	0.00	2.0e-01	-2.6	-5.3	1.4e-07	-0.64	0.04	0.59	FALSE
68	METSIM	Adipose	TUBGCP4	0.04	0.02	bslmm	277	0.02	6.4e-04	6.7	-5.8	9.2e-09	-0.75	0.02	0.95	FALSE
69	NTR	Blood	NUSAP1	0.03	0.03	lasso	3	0.04	4.9e-12	5.1	5.3	1.5e-07	0.10	0.49	0.51	FALSE
70	NTR	Blood	ZSCAN29	0.03	0.03	lasso	10	0.03	2.5e-09	7.1	-7.0	1.8e-12	-1.00	0.01	0.99	FALSE
71	YFS	Blood	MGA	0.01	0.00	blup	454	0.00	7.1e-02	2.4	5.1	3.1e-07	0.07	0.10	0.25	FALSE
72	YFS	Blood	SERF2	0.06	0.06	lasso	6	0.06	2.7e-20	5.6	-5.8	7.2e-09	-0.87	0.99	0.01	FALSE
73	YFS	Blood	TUBGCP4	0.07	0.05	blup	274	0.05	3.5e-17	7.0	-5.6	2.1e-08	-0.77	0.01	0.99	FALSE
74	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC729082	0.02	0.01	blup	44	0.02	2.9e-04	4.6	-5.2	1.6e-07	-0.09	0.02	0.95	FALSE
75	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PPIP5K1	0.05	0.03	blup	38	0.02	8.6e-04	5.6	5.9	4.1e-09	0.85	0.01	0.90	FALSE
76	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EHD4	0.05	0.02	blup	102	0.04	4.2e-05	5.5	-5.2	2.7e-07	0.07	0.00	0.99	FALSE
77	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NUSAP1	0.03	0.01	blup	40	0.02	3.4e-03	5.0	-5.2	1.5e-07	-0.06	0.06	0.73	FALSE
78	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZSCAN29	0.06	0.05	lasso	3	0.05	2.6e-06	7.1	-7.0	3.1e-12	-1.00	0.01	0.99	FALSE
79	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ZSCAN29	0.06	0.02	blup	40	0.03	1.3e-02	4.1	-6.5	7.2e-11	-0.96	0.01	0.69	FALSE
80	The Cancer Genome Atlas	Brain Lower Grade Glioma	NDUFAF1	0.03	0.04	lasso	3	0.04	3.2e-05	5.3	-5.3	9.4e-08	-0.09	0.02	0.98	FALSE
81	The Cancer Genome Atlas	Brain Lower Grade Glioma	TUBGCP4	0.05	0.02	blup	50	0.05	6.6e-06	-2.9	-5.7	1.1e-08	-0.65	0.07	0.78	FALSE
82	The Cancer Genome Atlas	Lung Adenocarcinoma	NDUFAF1	0.14	0.17	lasso	5	0.18	9.6e-21	5.5	5.3	1.0e-07	0.08	0.01	0.99	FALSE
83	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LCMT2	0.04	0.00	blup	39	0.01	1.5e-02	-2.8	5.6	2.5e-08	0.63	0.01	0.33	FALSE
84	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NDUFAF1	0.23	0.15	lasso	3	0.13	3.7e-06	5.2	5.4	6.5e-08	0.11	0.03	0.97	FALSE
85	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	NDUFAF1	0.18	0.21	blup	28	0.22	5.4e-09	5.5	5.3	1.4e-07	0.09	0.01	0.99	FALSE
86	The Cancer Genome Atlas	Prostate Adenocarcinoma	NDUFAF1	0.13	0.16	enet	8	0.17	2.2e-17	5.5	5.4	5.7e-08	0.08	0.01	0.99	FALSE
87	The Cancer Genome Atlas	Skin Cutaneous Melanoma	TP53BP1	0.54	0.00	blup	73	0.03	6.4e-02	-2.8	6.8	1.4e-11	0.79	0.02	0.21	FALSE
88	The Cancer Genome Atlas	Stomach Adenocarcinoma	CATSPER2	0.08	0.01	enet	5	0.06	5.4e-05	5.6	5.4	7.7e-08	0.70	0.00	0.93	FALSE
89	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ZSCAN29	0.10	0.08	lasso	4	0.07	2.2e-03	7.1	-7.1	1.7e-12	-1.00	0.01	0.81	FALSE
90	The Cancer Genome Atlas	Thyroid Carcinoma	NDUFAF1	0.32	0.38	enet	11	0.39	1.2e-39	5.5	5.4	6.3e-08	0.09	0.01	0.99	FALSE
91	The Cancer Genome Atlas	Thyroid Carcinoma	RTF1	0.04	0.02	lasso	3	0.02	4.0e-03	-6.1	-6.6	4.1e-11	-0.06	0.00	0.98	FALSE