Best TWAS P=9.47e-09 · Best GWAS P=5.42e-09 conditioned to 0.183
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | RP11-309G3.3 | 0.12 | 0.03 | enet | 7 | 0.03 | 1.3e-03 | 5.3 | -5.7 | 9.5e-09 | -0.93 | 0.01 | 0.98 | TRUE |
| 2 | YFS | Blood | IER5 | 0.12 | 0.09 | enet | 19 | 0.11 | 2.6e-35 | 5.8 | 5.7 | 9.5e-09 | 0.97 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | IER5 | 0.09 | 0.05 | blup | 52 | 0.04 | 9.0e-03 | 5.3 | 5.5 | 5.2e-08 | 0.96 | 0.01 | 0.92 | FALSE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | MR1 | 0.07 | 0.02 | blup | 57 | 0.06 | 2.5e-04 | -3.8 | 5.4 | 5.2e-08 | 0.72 | 0.03 | 0.73 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | IER5 | 0.05 | 0.02 | blup | 52 | 0.02 | 2.2e-03 | 5.2 | -5.5 | 3.6e-08 | -0.96 | 0.01 | 0.89 | FALSE |