Best TWAS P=2.03e-10 · Best GWAS P=1.01e-11 conditioned to 2.57e-11
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Transverse | WWOX | 0.49 | 0.00 | lasso | 15 | 0.02 | 6.0e-02 | 4.9 | 6.4 | 2.0e-10 | -0.02 | 0.24 | 0.06 | TRUE |
2 | GTEx | Esophagus Gastroesophageal Junction | WWOX | 0.58 | 0.00 | lasso | 19 | -0.01 | 6.1e-01 | -4.4 | 5.4 | 5.9e-08 | 0.07 | 0.22 | 0.04 | FALSE |
3 | GTEx | Skin Not Sun Exposed Suprapubic | WWOX | 0.42 | 0.16 | lasso | 7 | 0.14 | 6.2e-08 | -4.4 | 5.4 | 7.2e-08 | 0.08 | 0.96 | 0.00 | FALSE |
4 | GTEx | Thyroid | WWOX | 0.41 | 0.04 | enet | 43 | 0.12 | 1.1e-09 | -4.3 | 5.4 | 7.1e-08 | 0.05 | 0.98 | 0.00 | FALSE |