Best TWAS P=1.09e-24 · Best GWAS P=9.63e-30 conditioned to 1.12e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SERPINB11 | 0.14 | 0.19 | lasso | 6 | 0.19 | 7.0e-21 | -10.3 | -10.3 | 1.2e-24 | 0.77 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SERPINB11 | 0.08 | 0.06 | lasso | 3 | 0.08 | 1.3e-09 | -4.1 | -7.7 | 1.0e-14 | 0.58 | 0.04 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SERPINB11 | 0.16 | 0.24 | lasso | 5 | 0.22 | 3.6e-23 | -10.3 | -10.3 | 1.1e-24 | 0.77 | 0.01 | 0.99 | FALSE |