Best TWAS P=1.47e-11 · Best GWAS P=2.08e-13 conditioned to 1.07e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | MALT1 | 0.12 | 0.08 | lasso | 4 | 0.05 | 4.1e-05 | -6.7 | 6.8 | 1.5e-11 | 0.14 | 0.12 | 0.86 | TRUE |
| 2 | GTEx | Muscle Skeletal | MALT1 | 0.11 | 0.04 | lasso | 4 | 0.04 | 7.4e-05 | -6.7 | 6.5 | 7.5e-11 | 0.12 | 0.12 | 0.86 | FALSE |
| 3 | GTEx | Nerve Tibial | MALT1 | 0.15 | 0.09 | lasso | 2 | 0.07 | 6.9e-06 | -6.0 | 6.3 | 2.1e-10 | 0.13 | 0.18 | 0.78 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MALT1 | 0.04 | 0.05 | lasso | 1 | 0.05 | 4.6e-06 | -6.4 | 6.4 | 1.6e-10 | 0.13 | 0.00 | 0.99 | FALSE |