Best TWAS P=2.33e-17 · Best GWAS P=5.79e-17 conditioned to 0.0198
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | DOK6 | 0.18 | 0.18 | lasso | 5 | 0.18 | 3.2e-56 | 8.3 | 8.4 | 4.3e-17 | 0.98 | 0.00 | 1.00 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CD226 | 0.04 | 0.04 | enet | 7 | 0.05 | 5.3e-10 | 8.2 | -7.8 | 4.9e-15 | -0.92 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CD226 | 0.09 | 0.03 | blup | 76 | 0.06 | 1.7e-07 | 8.2 | -8.5 | 2.3e-17 | -0.84 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CD226 | 0.03 | 0.01 | enet | 7 | 0.02 | 4.3e-03 | 2.4 | -6.6 | 5.6e-11 | -0.53 | 0.02 | 0.62 | FALSE |
| 5 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | CD226 | 0.40 | 0.05 | enet | 23 | 0.08 | 2.6e-03 | 7.1 | -5.5 | 4.3e-08 | -0.41 | 0.02 | 0.20 | FALSE |