Best TWAS P=3.59e-10 · Best GWAS P=2.27e-11 conditioned to 0.00912
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | AC005786.7 | 0.16 | 0.00 | lasso | 4 | 0.00 | 0.23300 | -6.6 | -6.3 | 3.6e-10 | 0.86 | 0.01 | 0.74 | TRUE |
| 2 | GTEx | Colon Sigmoid | MAP2K2 | 0.20 | 0.11 | lasso | 3 | 0.13 | 0.00003 | 5.2 | 5.3 | 1.5e-07 | 0.01 | 0.04 | 0.74 | TRUE |
| 3 | GTEx | Esophagus Muscularis | SGTA | 0.16 | 0.00 | lasso | 4 | 0.02 | 0.01140 | -3.1 | 6.0 | 1.6e-09 | -0.62 | 0.04 | 0.18 | FALSE |