Best TWAS P=2.27e-08 · Best GWAS P=1.04e-07 conditioned to 0.211
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CAPS | 0.06 | 0.09 | lasso | 1 | 0.07 | 2.0e-06 | -5.2 | 5.2 | 1.7e-07 | -0.98 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Heart Left Ventricle | VMAC | 0.17 | 0.00 | lasso | 9 | 0.00 | 4.7e-01 | -5.3 | -5.5 | 3.9e-08 | 0.82 | 0.01 | 0.69 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | AC104532.4 | 0.10 | 0.13 | lasso | 2 | 0.12 | 6.1e-10 | -5.2 | 5.2 | 1.7e-07 | -0.98 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Thyroid | CAPS | 0.10 | 0.10 | lasso | 1 | 0.07 | 7.2e-06 | -5.2 | 5.2 | 1.7e-07 | -0.98 | 0.00 | 0.99 | FALSE |
| 5 | GTEx | Thyroid | AC104532.4 | 0.07 | 0.09 | lasso | 3 | 0.08 | 9.3e-07 | -5.2 | 5.3 | 1.1e-07 | -0.98 | 0.00 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | VMAC | 0.04 | 0.01 | lasso | 3 | 0.02 | 2.4e-05 | -5.1 | -5.6 | 2.3e-08 | 0.83 | 0.01 | 0.98 | TRUE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FUT5 | 0.11 | 0.05 | lasso | 2 | 0.08 | 7.3e-09 | -5.1 | -5.2 | 1.9e-07 | 0.80 | 0.01 | 0.99 | FALSE |
| 8 | The Cancer Genome Atlas | Rectum Adenocarcinoma | VMAC | 0.15 | 0.04 | blup | 44 | 0.10 | 3.1e-03 | -4.5 | 5.2 | 2.5e-07 | -0.90 | 0.01 | 0.39 | FALSE |