Best TWAS P=2.71e-07 · Best GWAS P=5.77e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | ZNF414 | 0.18 | 0.09 | lasso | 3 | 0.07 | 3.2e-05 | -5.0 | -5.1 | 2.7e-07 | 0.96 | 0.00 | 0.99 | TRUE |
| 2 | GTEx | Nerve Tibial | ZNF414 | 0.18 | 0.08 | lasso | 6 | 0.09 | 5.3e-07 | -4.9 | -5.1 | 3.1e-07 | 0.95 | 0.01 | 0.99 | FALSE |