[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr19:10,283,932-13,954,633

Best TWAS P=1.09e-11 · Best GWAS P=5.38e-11 conditioned to 3.72e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts CARM1 0.11 0.01 lasso 4 0.00 6.9e-01 6.2 6.8 1.1e-11 0.94 0.02 0.93 TRUE
2 GTEx Esophagus Mucosa SMARCA4 0.18 0.03 enet 15 0.09 8.2e-07 5.4 -5.4 5.9e-08 -0.64 0.33 0.65 FALSE
3 GTEx Nerve Tibial STX10 0.12 0.05 enet 32 0.06 3.2e-05 3.8 -5.6 1.7e-08 -0.07 0.01 0.04 TRUE
4 GTEx Skin Sun Exposed Lower leg SMARCA4 0.15 0.10 enet 25 0.15 1.4e-12 5.6 -5.2 1.7e-07 -0.77 0.11 0.89 FALSE
5 GTEx Skin Sun Exposed Lower leg YIPF2 0.05 0.05 lasso 2 0.04 1.6e-04 5.7 -5.8 5.3e-09 -0.92 0.02 0.97 FALSE
6 GTEx Testis ZNF69 0.26 0.09 enet 12 0.17 4.1e-08 -5.0 5.6 2.5e-08 0.18 0.01 0.98 TRUE
7 ROSMAP Brain Pre-frontal Cortex ZNF439 0.21 0.13 lasso 9 0.15 3.8e-19 -5.0 5.2 1.9e-07 0.17 0.01 0.99 FALSE
8 YFS Blood SMARCA4 0.02 0.01 enet 3 0.00 9.2e-03 4.1 -5.3 1.1e-07 -0.72 0.08 0.52 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C19orf52 0.04 0.04 blup 27 0.03 1.7e-04 5.5 -5.5 3.8e-08 -0.87 0.06 0.92 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma C19orf52 0.05 0.06 lasso 4 0.06 2.5e-06 6.2 -6.2 4.2e-10 -0.95 0.02 0.98 FALSE