Best TWAS P=8.27e-20 · Best GWAS P=1.53e-17 conditioned to 0.000147
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | RUVBL2 | 0.34 | 0.21 | lasso | 6 | 0.10 | 2.8e-03 | -7.9 | 7.4 | 1.0e-13 | -0.57 | 0.06 | 0.74 | FALSE |
| 2 | YFS | Blood | BAX | 0.04 | 0.02 | lasso | 4 | 0.02 | 1.3e-08 | -8.1 | -9.1 | 8.3e-20 | 0.60 | 0.10 | 0.90 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | NUCB1 | 0.07 | 0.00 | blup | 65 | 0.04 | 2.6e-05 | -1.8 | 5.9 | 3.4e-09 | -0.59 | 0.01 | 0.86 | FALSE |