Best TWAS P=4.4e-12 · Best GWAS P=6.29e-11 conditioned to 0.00182
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | ST3GAL6 | 0.07 | 0.01 | enet | 22 | 0.01 | 0.02260 | 4.7 | -6.9 | 4.4e-12 | -0.58 | 0.14 | 0.61 | TRUE |
2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | ST3GAL6 | 0.14 | 0.05 | blup | 68 | 0.09 | 0.00019 | -3.1 | -5.3 | 1.3e-07 | -0.35 | 0.04 | 0.08 | FALSE |