Best TWAS P=1.28e-09 · Best GWAS P=4.05e-12 conditioned to 6.08e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | CSTA | 0.16 | 0.17 | lasso | 3 | 0.16 | 1.5e-10 | 5.4 | -5.1 | 2.8e-07 | -0.57 | 0.98 | 0.02 | FALSE |
| 2 | GTEx | Liver | RP11-299J3.8 | 0.24 | -0.01 | enet | 15 | 0.00 | 3.4e-01 | 6.3 | -6.1 | 1.3e-09 | -0.02 | 0.08 | 0.07 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CSTA | 0.04 | 0.00 | enet | 9 | 0.02 | 1.2e-03 | 3.0 | -5.4 | 5.1e-08 | -0.56 | 0.03 | 0.33 | TRUE |