TWAS hub - CSTA

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1720	0.0580	4.3e-03	0.016	NA	0.038	NA	0.031	4.9e-02	NA	4.5e-03	NA	9.3e-03
2	GTEx	Esophagus Mucosa	0.1590	0.0540	6.8e-04	0.171	NA	0.146	NA	0.155	1.5e-11	NA	5.6e-10	NA	1.5e-10
3	GTEx	Heart Atrial Appendage	0.1880	0.0690	5.8e-03	0.009	NA	0.007	NA	0.010	1.2e-01	NA	1.5e-01	NA	1.1e-01
4	NTR	Blood	0.0156	0.0091	3.9e-02	0.005	-0.001	0.004	0.002	0.006	8.3e-03	7.2e-01	1.4e-02	4.3e-02	2.6e-03
5	YFS	Blood	0.3997	0.0440	0.0e+00	0.196	0.391	0.398	0.394	0.389	6.2e-62	2.9e-138	2.9e-141	2.6e-139	4.1e-137
6	TCGA	Breast Invasive Carcinoma	0.0280	0.0132	4.8e-04	0.009	0.023	0.016	NA	0.015	4.0e-03	1.3e-05	2.7e-04	NA	3.5e-04
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.0700	0.0483	5.7e-03	-0.002	0.014	0.006	NA	-0.002	9.2e-01	9.8e-03	5.9e-02	NA	9.7e-01
8	TCGA	Lung Squamous Cell Carcinoma	0.0428	0.0258	6.4e-03	0.004	0.019	0.022	NA	0.013	1.0e-01	2.8e-03	1.2e-03	NA	1.2e-02
9	TCGA	Prostate Adenocarcinoma	0.0841	0.0307	9.9e-07	0.051	0.062	0.042	NA	0.049	4.2e-06	4.7e-07	2.9e-05	NA	6.5e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Pulse rate, automated reading	5.9	19.0	46.4	0.7	5.7	-2.6	3.2	6.8	3.0	2.6	4.7	6.0
Diastolic blood pressure, automated reading	5.4	16.7	30.4	2.7	4.6	-1.6	3.2	5.1	3.7	4.1	4.7	5.5
Basal cell carcinoma (self-reported)	5.2	6.2	15.5	2.7	2.6	-0.7	1.6	2.4	2.2	2.5	3.9	2.5
Ever unenthusiastic/disinterested for a whole week	5.0	6.1	11.2	-2.4	-2.4	-0.9	-3.1	-2.3	-2.7	-2.3	-2.1	-3.4
Bilateral oophorectomy (both ovaries removed)	4.0	4.6	12.8	-2.8	-1.2	-3.6	-2.5	1.2	-1.4	-2.8	1.2	-0.9
Neuroticism (2016)	3.6	5.1	21.4	-0.5	-1.6	-4.6	-2.2	1.4	-2.5	-2.1	0.5	-2.0
Heart disease (siblings)	3.5	4.3	7.8	-2.3	-2.0	-1.5	-2.3	-1.3	-2.2	-2.8	-0.7	-2.6
Pulse rate	3.3	5.5	10.4	-1.5	3.2	-0.1	2.4	3.2	2.2	1.8	1.8	3.2
Supplements: Calcium	3.2	3.5	13.2	0.7	-0.3	3.2	1.8	-1.0	1.1	1.1	-3.6	1.0
Mouth/teeth dental problems: Dentures	3.1	5.2	10.5	-2.1	-2.4	-0.9	-2.5	-1.0	-2.8	-3.2	-2.0	-2.6
Frequency of tenseness / restlessness in last 2 weeks	3.0	4.7	9.9	-1.2	-2.0	-2.9	-1.6	0.2	-3.2	-2.9	-1.6	-2.2
LDL Cholesterol	2.6	4.1	16.7	-0.4	-2.1	-4.1	-1.6	-0.7	-1.8	-2.3	1.0	-1.7
Commuting to job workplace: Car/motor vehicle	2.6	2.9	6.6	-0.1	-1.6	0.3	-1.6	-2.2	-1.7	-2.0	-2.6	-1.6
HbA1C	2.5	2.8	13.7	1.0	0.3	0.0	3.7	1.0	1.5	2.2	1.1	0.8
Systolic Blood Pressure	2.5	12.7	24.1	3.7	4.3	-1.5	0.8	4.3	2.9	2.5	4.7	4.9
Ever had hysterectomy (womb removed)	2.3	2.5	6.4	-2.5	-0.9	-1.2	-2.5	0.1	-1.3	-2.3	-0.3	-1.0
Allergy or Eczema	2.2	5.9	16.2	0.5	-2.9	1.9	-0.2	-4.0	-1.9	-1.2	-3.2	-3.0
Qualifications: None of the above	2.2	4.8	18.1	-2.1	-1.4	-4.2	-1.9	-0.0	-1.8	-2.6	0.6	-2.1
Qualifications: A levels/AS levels or equivalent	2.2	4.8	8.8	1.2	2.3	1.1	2.9	2.2	2.5	2.1	1.7	3.0
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.6	4.4	1.3	1.7	0.6	0.9	2.0	1.9	2.0	1.4	2.1
Mean time to correctly identify matches	2.2	4.1	10.6	-0.2	-2.1	-0.9	-1.8	-0.1	-3.3	-3.2	-1.6	-2.3
Heart disease (mother)	2.2	2.7	5.8	0.4	2.2	1.8	1.0	0.9	1.7	2.4	-0.1	2.2
Ulcerative Colitis (UC)	2.1	3.9	7.6	-0.9	-2.8	1.4	-1.6	-1.7	-2.2	-1.6	-2.5	-2.4
Ulcerative Colitis	2.1	3.1	5.1	-1.3	-2.3	0.5	-1.2	-1.6	-2.1	-1.7	-2.1	-2.2
Bipolar Disorder (2018)	2.0	3.1	6.7	-1.9	-2.0	-1.9	-1.6	-1.3	-1.4	-2.6	-1.3	-1.5
Systolic blood pressure, automated reading	2.0	5.8	12.2	2.3	2.9	-0.8	0.5	3.5	1.8	1.7	2.8	3.4
Mouth/teeth dental problems	2.0	3.0	7.8	0.9	2.8	0.5	1.3	2.0	1.5	1.5	1.9	2.0
Angina (self-reported)	2.0	2.7	7.7	-1.8	-0.7	-1.9	-2.8	-0.3	-1.5	-1.8	0.3	-1.9
Wears glasses or contact lenses	2.0	2.3	5.1	-1.8	0.2	-0.3	-1.8	0.2	-2.2	-2.1	-1.8	-1.3
Illnesses of father: Heart disease	1.9	2.6	4.5	-1.7	-1.1	0.1	-1.8	-1.5	-1.5	-1.7	-2.1	-2.0
Ever depressed for a whole week	1.9	2.3	5.1	-1.1	-1.7	0.3	-0.9	-1.6	-1.8	-1.3	-2.3	-1.7
Rheumatoid Arthritis	1.8	2.5	9.6	1.1	-2.2	1.1	0.7	-3.1	-0.4	-0.1	-1.5	-1.6
Medication: Cholesterol lowering	1.8	2.8	15.8	0.8	-0.6	-4.0	-1.5	0.3	-1.2	-1.1	1.3	-1.1
Mouth/teeth dental problems: Bleeding gums	1.8	2.4	4.5	1.7	-0.4	2.0	1.4	-0.4	2.0	2.1	-0.6	1.7
Medication: Paracetamol	1.8	2.9	6.2	-0.1	1.9	-0.9	0.5	2.4	1.7	1.9	1.8	2.5
HDL Cholesterol	1.7	2.8	5.4	-1.2	-1.5	-1.3	-1.7	-1.5	-1.9	-1.8	-1.6	-2.3
Medication: Co-codamol	1.7	1.9	4.5	-0.7	-1.9	-1.7	-0.2	-0.5	-1.8	-1.4	-1.0	-2.1
Average weekly fortified wine intake	1.7	2.0	5.1	-0.2	2.3	-0.6	0.4	1.3	1.6	1.0	2.1	1.6
Hayfever, allergic rhinitis or eczema	1.7	3.7	9.8	0.9	-2.4	1.8	0.7	-3.1	-1.3	-0.5	-2.6	-2.1
Loneliness, isolation	1.7	2.3	4.9	0.8	1.8	0.3	1.1	2.2	1.5	1.1	1.6	2.1
Medication: Bendroflumethiazide	1.7	2.5	10.1	-0.8	1.6	-2.1	0.7	3.2	0.1	-0.3	1.8	1.1
Medication: Atorvastatin	1.7	2.1	6.1	-0.9	-0.6	-1.3	-2.5	-0.1	-2.1	-1.3	0.3	-2.0
Major Depression (MDD)	1.6	1.9	5.0	-0.5	-1.1	-1.8	-1.4	1.1	-2.0	-2.2	-0.3	-0.6
Average weekly spirits intake	1.6	2.0	7.8	-1.0	-1.5	1.2	0.1	-1.7	-0.6	-1.2	-2.8	-0.7
Sensitivity / hurt feelings	1.6	2.8	12.0	-0.6	-1.4	-3.5	-0.4	0.8	-1.9	-1.7	-0.1	-1.7
Loud music exposure frequency	1.6	1.8	4.8	1.4	0.5	2.2	1.8	-0.4	1.4	1.7	-0.4	0.8
Exposure to tobacco smoke outside home	1.6	2.1	6.5	1.3	1.4	-1.9	0.2	2.5	-0.1	-0.3	2.0	1.2
Mouth/teeth dental problems: Loose teeth	1.6	1.9	5.8	-0.2	-2.4	-0.9	-0.7	-1.9	-1.0	-0.8	-0.7	-2.0
Medication: Aspirin	1.6	2.1	7.8	-2.8	0.6	-2.6	-0.7	0.6	-0.1	-0.5	1.4	-0.9
Illnesses of siblings: Diabetes	1.6	1.9	4.8	-0.8	-1.9	-0.4	-1.0	-0.9	-1.8	-1.7	-0.6	-2.2
Miserableness	1.6	2.7	5.3	-1.2	-2.0	-1.8	-0.6	-1.6	-1.8	-1.4	-1.5	-2.3
Hearing aid user	1.6	1.8	5.3	-0.0	-0.7	1.9	2.3	-0.9	0.4	1.3	-1.9	-0.6
Financial situation satisfaction	1.6	1.9	5.3	1.2	0.8	2.3	1.6	-0.3	1.5	1.9	-0.1	1.3
Schizophrenia vs Biploar Disorder	1.5	2.0	6.2	1.6	2.3	2.5	0.5	1.0	-0.1	1.1	0.2	1.0
Reaction Time	1.5	2.8	7.2	0.0	-1.9	-0.3	-0.9	-0.5	-2.7	-2.6	-1.6	-2.0
Type 2 Diabetes (T2D) (2012)	1.5	1.7	4.2	-1.5	-1.1	-1.3	-1.7	-0.7	-1.1	-1.1	0.5	-2.0
Angina	1.5	2.0	6.2	-1.4	-0.4	-1.6	-2.5	-0.0	-1.3	-1.6	0.4	-1.6
Medication: Metformin	1.5	2.2	6.9	-1.5	-1.6	-2.6	-1.1	-0.5	-0.9	-0.5	1.0	-2.0
Medication: Ramipril	1.5	1.9	8.5	-0.5	-1.2	-2.9	-0.5	0.3	-1.2	-1.3	1.0	-1.4
Pulse wave Arterial Stiffness index	1.5	1.8	3.8	-0.2	1.7	1.3	1.4	0.9	1.4	1.5	-0.4	1.9
Qualifications: O levels/GCSEs or equivalent	1.5	2.3	6.2	0.0	1.1	1.6	2.5	1.6	1.6	1.3	0.4	2.1
Heart attack/myocardial infarction (self-reported)	1.5	1.9	4.6	0.3	-1.0	-1.5	-2.2	-0.5	-1.5	-1.6	0.6	-2.0
Bipolar Disorder (2011)	1.4	1.4	5.1	-2.2	-1.1	-1.3	0.4	-0.9	-0.7	-1.0	0.3	-1.3
Number of live births	1.4	1.9	6.8	-0.3	-0.7	-2.6	-1.7	0.8	-1.5	-1.9	0.1	-0.8
Prospective memory result	1.4	1.7	4.7	1.0	-0.3	2.2	-0.7	-2.0	0.9	0.9	-1.8	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.1	4.5	0.6	-1.4	-1.6	-1.3	-0.6	-2.1	-1.7	-1.7	-1.5
Commuting to job workplace: Walk	1.4	1.5	4.2	0.3	1.0	0.1	1.3	0.0	2.0	1.4	1.5	1.5
Back pain experienced in last month	1.4	2.0	6.6	-2.6	-1.1	-1.2	-0.5	-1.0	-1.0	-1.3	-1.1	-1.8
Medication: Aspirin	1.4	1.9	7.0	-2.5	0.0	-2.7	-0.8	0.2	-0.5	-0.6	0.9	-1.3
Number of self-reported non-cancer illnesses	1.4	2.4	7.4	-1.3	-0.3	-1.6	-1.3	1.0	-2.7	-2.4	-1.2	-0.7
Blood Eosinophil Count	1.3	10.0	29.7	-0.4	-5.1	1.3	0.4	-3.4	-2.3	-3.3	-5.4	-2.2
Vitamin and mineral supplements	1.3	1.7	5.8	1.6	-0.4	-0.9	0.4	-2.4	1.4	1.4	1.3	-0.4
Diabetes (mother)	1.3	1.7	5.3	-0.9	0.0	0.2	1.5	0.6	1.7	1.6	2.3	0.8
Mineral and other dietary supplements	1.3	1.7	7.5	2.7	0.6	0.1	-0.2	-0.5	1.6	1.6	1.1	1.1
Mother’s age at death	1.3	1.6	4.2	1.3	1.0	1.6	-0.0	-0.0	1.5	2.0	0.8	1.4
Medication: Blood pressure	1.3	2.4	8.1	-0.4	1.4	-2.0	0.1	2.8	0.4	0.4	2.4	1.3
Risk taking	1.3	1.9	12.4	-3.5	0.5	0.1	-0.2	-1.3	1.1	0.8	-0.0	-1.1
Worry (Nagel 2018)	1.2	2.6	5.3	2.0	1.1	-0.4	1.7	1.6	1.7	2.3	0.9	1.9
Crohns Disease (2017)	1.2	2.7	4.9	-1.4	2.2	0.7	0.1	2.1	2.2	1.3	1.4	2.0
Mean Putamen Volume	1.2	1.4	3.6	-1.1	-1.4	1.6	0.1	-1.9	0.0	-0.4	-1.5	-0.9
Number of treatments/medications taken	1.2	2.2	7.6	-1.4	0.2	-2.8	-1.4	1.0	-1.8	-1.8	-0.4	-0.7
Nervous feelings	1.2	2.2	4.1	1.6	1.0	-1.8	0.5	1.4	1.2	1.7	2.0	1.5
Heart attack	1.2	1.5	4.6	0.2	-0.8	-1.1	-2.2	-0.6	-1.2	-1.4	0.5	-1.8
Diabetes (self-reported)	1.2	1.8	4.3	-0.7	-1.4	-2.1	-1.4	-0.0	-1.7	-1.4	-0.3	-1.6
Medication: Simvastatin	1.2	1.7	11.0	-0.6	-0.0	-3.3	-0.9	0.7	-0.3	-0.8	1.4	-0.4
Pulse wave peak to peak time	1.2	1.4	3.2	0.1	-1.6	-0.9	-1.3	-1.0	-1.3	-1.4	0.2	-1.8
Illnesses of father: None of the above (group 1)	1.2	1.4	3.8	-0.5	1.0	-0.7	0.8	1.1	1.5	1.0	1.5	1.9
Pain experienced in last month	1.2	2.0	5.1	1.6	1.1	2.3	0.9	0.1	1.5	1.6	1.0	1.5
Coronary Artery Disease (CAD)	1.1	1.3	2.4	-1.6	-1.3	0.6	-0.8	-1.1	-1.3	-1.0	-0.8	-1.5
Hearing difficulty/problems: Yes	1.1	1.7	6.5	0.7	0.8	1.5	2.5	0.1	1.2	1.8	0.4	0.7
High blood pressure (mother)	1.1	1.5	2.8	0.6	1.4	0.2	1.6	1.0	1.4	1.4	1.0	1.7
Time employed in main current job	1.1	1.3	5.0	-0.9	0.4	2.2	1.2	0.1	1.0	1.1	-1.2	0.7
Falls in the last year	1.1	1.4	4.5	-2.1	-0.5	2.0	-0.3	-1.0	0.3	0.5	-1.4	-0.6
Ever highly irritable/argumentative for 2 days	1.1	1.4	2.7	-0.9	-1.3	0.4	-0.8	-1.2	-1.7	-1.0	-1.4	-1.4
Age at first live birth	1.1	2.0	8.6	0.8	1.4	2.9	0.9	-0.6	1.0	1.6	-1.0	1.0
Medication for cholesterol	1.1	1.7	5.4	1.0	-0.5	2.3	0.1	-2.1	-0.4	-0.4	-1.8	-0.4
Commuting to job workplace: Cycle	1.1	1.3	3.8	0.2	-0.0	2.0	1.8	-0.6	1.4	1.4	-0.5	0.7
Crohns Disease (2012)	1.0	1.5	4.2	-0.9	2.0	-0.2	-1.0	1.7	1.0	0.3	1.4	1.3
Hypothyroidism (self reported)	1.0	2.2	7.9	-0.5	-2.2	0.5	1.7	-1.3	-1.0	-0.9	-2.8	-0.6
Hand grip strength (left)	1.0	2.7	14.0	2.0	0.7	3.7	-0.0	-0.4	0.7	1.8	-1.1	0.7
Medication for hormone replacement therapy	1.0	1.2	2.5	-0.4	0.2	-1.2	0.2	1.4	1.4	1.0	1.6	1.1
Pack years adult smoking proportion	1.0	1.5	3.8	-0.3	1.8	-0.0	-0.8	0.3	1.9	1.4	1.2	1.4
Hand grip strength (right)	1.0	2.8	16.9	1.3	0.3	4.1	0.7	-0.4	1.0	1.5	-1.3	1.0
Relative age voice broke	1.0	1.6	4.1	1.8	0.6	1.0	1.2	0.0	1.3	2.0	1.3	1.0
Hair/balding pattern: Pattern 3	1.0	1.5	3.9	1.9	0.5	-1.5	1.0	2.0	-0.1	0.3	1.3	1.0
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	2.7	-1.1	1.6	-0.0	1.0	1.5	1.0	0.5	1.0	1.1
Depression (self-reported)	1.0	1.2	2.6	-0.2	-0.6	-1.6	-1.5	-0.3	-1.6	-1.2	-0.8	-1.1
Medication: Ibuprofen	1.0	1.2	3.4	-1.8	-0.8	-1.5	-0.8	-0.9	-0.5	-1.0	-0.4	-1.4
Hypertension (Self-reported)	1.0	2.9	9.7	0.5	1.2	-3.1	-0.1	2.6	0.3	-0.3	2.3	1.6
Smoking status: Previous	1.0	1.5	4.7	-1.0	-1.4	0.4	-1.2	-0.1	-1.5	-2.2	-1.3	-0.5
Handedness (chirality/laterality): Left-handed	1.0	1.2	4.7	0.2	0.7	-2.2	-0.7	1.2	-0.6	-0.7	1.6	-0.1
Smoking status: Current	1.0	1.6	7.7	-0.1	0.3	2.8	0.0	-1.6	0.8	1.0	-1.4	-0.1
Medication: Paracetamol	1.0	1.5	3.1	-1.2	1.7	-0.4	-0.4	1.8	0.9	0.8	1.0	1.7
Primary Biliary Cirrhosis	0.9	1.3	2.3	-0.1	1.5	1.3	1.5	1.0	0.9	1.2	0.9	1.4
Cardiovascular Disease	0.9	3.1	9.2	0.6	1.3	-3.0	1.0	2.3	0.9	0.6	2.3	2.1
Lung FVC	0.9	4.7	12.0	-0.6	-3.1	2.0	-2.4	-3.5	-1.0	-0.9	-2.2	-2.1
Current tobacco smoking	0.9	1.5	6.5	-0.5	0.1	2.5	-0.4	-1.8	0.5	0.6	-1.5	-0.5
Fed-up feelings	0.9	1.6	3.1	-1.5	-0.4	-1.7	-1.5	-0.5	-1.2	-1.4	-1.8	-0.6
Qualifications: CSEs or equivalent	0.9	1.2	3.1	1.7	0.1	-1.4	0.5	1.5	-0.1	0.4	1.8	0.7
Supplements: Glucosamine	0.9	1.2	4.3	-2.1	-1.0	-1.3	0.9	0.3	-0.8	-1.1	0.3	-0.7
Past tobacco smoking	0.9	1.7	4.6	1.1	1.2	-1.6	1.1	0.4	1.1	1.7	2.1	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	5.7	-0.7	-1.1	-2.4	-1.6	0.9	-1.8	-1.3	0.3	-1.6
Allergy	0.9	2.0	6.0	-0.7	1.3	-1.3	-1.6	2.5	0.5	-0.0	1.8	1.6
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	7.6	-2.1	0.3	2.8	-0.3	-0.5	0.3	0.4	-1.0	-0.2
Qualifications: College or University degree	0.9	2.7	5.2	0.9	2.3	2.0	1.1	1.6	1.6	1.9	-0.1	2.0
Medication for pain relief, constipation, heartburn	0.9	1.6	5.7	1.6	-1.1	2.4	1.0	-1.4	0.3	0.0	-1.2	-0.4
Ever had bowel cancer screening	0.9	1.0	3.3	0.0	1.5	-0.2	0.9	1.8	0.3	0.3	1.1	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	3.0	0.8	1.7	-0.3	0.5	1.4	0.7	0.5	0.4	1.5
Ever taken oral contraceptive pill	0.9	1.0	5.0	0.5	-0.8	1.4	0.9	-0.6	-0.1	-0.2	-2.2	-0.1
Medication: Lisinopril	0.9	1.2	3.1	-0.3	-0.9	-1.8	-1.3	-0.8	-0.9	-1.6	-0.8	-0.4
Number of operations (self-reported)	0.9	1.3	4.6	0.1	-0.1	-0.2	-1.9	0.7	-1.6	-2.1	-0.7	-0.4
Vascular/heart problems diagnosed by doctor	0.9	2.4	9.7	-0.8	-0.8	3.1	0.6	-2.1	-0.0	0.4	-2.2	-1.2
Lupus	0.8	1.2	4.4	0.9	0.7	0.1	1.8	2.1	-0.2	0.6	1.1	0.8
High blood pressure	0.8	2.1	7.8	0.7	0.9	-2.8	-0.5	2.1	0.1	-0.5	1.9	1.4
Alcohol usually taken with meals	0.8	1.3	2.7	1.0	1.0	1.7	1.2	1.2	1.1	0.8	-0.5	1.4
Exposure to tobacco smoke at home	0.8	0.9	1.6	1.2	1.3	0.2	0.7	0.2	1.3	1.1	1.0	0.5
Number of children fathered	0.8	0.9	3.4	0.8	0.9	-0.2	1.8	-0.1	1.5	0.9	0.1	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	3.0	1.3	1.6	0.1	-0.3	0.8	-0.2	-0.3	1.7	0.7
Overall health rating	0.8	1.6	3.1	1.3	1.5	-0.6	1.7	1.7	0.7	0.9	0.2	1.8
Supplements: Vitamin C	0.8	0.9	2.1	-1.1	0.7	1.3	0.5	1.0	-0.1	-0.9	-1.5	0.7
Qualifications: nursing, teaching	0.8	1.3	3.6	-0.3	1.9	1.5	0.8	0.6	1.3	1.1	0.3	1.3
High cholesterol (Self-reported)	0.8	1.4	7.2	1.1	0.3	-2.7	-1.2	0.6	-0.6	-0.3	1.2	-0.2
Pack years of smoking	0.8	1.2	3.0	-0.3	1.5	0.0	-1.2	0.1	1.7	1.2	1.0	1.1
Alzheimer’s Disease (in mother)	0.7	0.8	2.6	0.3	-0.6	0.6	-0.9	-1.6	-0.7	-0.5	-1.1	-1.2
Blood Platelet Count	0.7	8.3	15.1	1.1	2.9	-1.8	1.3	3.2	3.9	3.4	2.9	3.8
Smoking Status	0.7	1.7	6.9	0.2	-1.4	2.6	-0.6	-1.6	-0.2	-0.5	-1.8	-0.6
Severe depression (siblings)	0.7	0.8	2.9	-1.0	-0.6	1.5	0.5	-0.6	-0.4	-0.1	-1.7	-0.5
Medication: Atenolol	0.7	0.9	2.9	-1.1	-0.3	-1.7	-0.7	0.7	-0.5	-1.3	0.6	-0.7
Hearing difficulty/problems with background noise	0.7	1.1	2.8	-0.8	-0.9	0.3	0.3	-1.5	-1.1	-0.9	-1.0	-1.7
Hair/balding pattern: Pattern 2	0.7	0.9	2.2	0.3	0.9	-1.5	-0.6	-0.4	1.4	0.3	1.1	1.0
Illnesses of siblings	0.7	1.0	3.5	-0.2	1.2	0.2	1.0	0.5	1.1	1.9	0.6	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	3.1	-1.5	-0.4	-1.8	-0.7	-0.0	-0.4	-0.7	0.1	-1.0
Illnesses of mother	0.7	0.9	1.8	-0.2	-1.1	-0.7	-1.1	-0.2	-1.2	-1.3	0.6	-1.4
Tense / ‘highly strung’	0.7	1.1	3.7	0.1	0.2	-1.9	0.2	1.9	0.3	0.5	1.4	0.8
Hair/balding pattern: Pattern 4	0.7	1.6	3.4	0.9	1.1	-0.0	1.3	1.2	1.4	1.2	1.8	1.5
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	6.3	-0.1	-1.1	1.2	1.2	-1.1	-0.7	-0.2	-2.5	-0.4
Medication: Amlodipine	0.7	0.9	4.1	0.5	0.3	-1.0	0.0	1.1	0.6	-0.0	2.0	1.2
Medication: Ventolin 100micrograms inhaler	0.7	0.9	4.2	-0.9	-0.5	1.3	0.6	-2.1	-0.0	0.1	-0.7	-0.6
Migraine (self-reported)	0.7	0.8	2.4	0.4	0.2	-1.2	-1.5	0.3	-1.2	-0.6	-1.0	-0.8
Medication: Seretide 50 evohaler	0.7	0.8	2.2	1.3	1.0	0.2	1.5	-0.2	0.7	0.5	-0.8	0.9
Leg pain on walking	0.7	0.9	2.7	-1.1	-0.6	-0.4	1.1	-1.6	1.2	0.9	-0.4	-0.6
Osteoporosis (self-reported)	0.7	0.8	4.1	0.7	-0.4	0.7	2.0	1.0	-1.1	0.2	-0.2	-0.1
Osteoarthritis (self-reported)	0.7	1.0	2.6	-0.5	1.3	-1.3	0.3	1.6	0.2	0.5	1.4	0.6
Tinnitus: Yes, now most or all of the time	0.7	0.9	2.6	-0.7	-0.7	-0.4	0.5	-1.6	-0.5	-0.6	-1.6	-0.8
Ever smoked	0.7	1.3	4.0	-0.8	-0.8	1.9	-0.9	-0.4	-0.6	-1.1	-2.0	-0.2
Cholesterol lowering medication	0.7	1.1	2.9	-1.1	-0.8	-1.7	-1.3	0.3	-1.1	-0.8	0.0	-1.2
Prostate Cancer	0.6	0.8	2.0	0.6	1.1	-1.2	0.3	1.0	0.8	0.2	1.4	0.9
Heel T-Score	0.6	4.5	7.8	-1.6	-1.3	-2.7	-1.9	2.8	-2.5	-2.5	1.6	-1.4
Frequency of depressed mood in last 2 weeks	0.6	0.8	5.7	-0.2	-0.0	-2.4	-0.1	1.1	-0.2	-0.4	-0.3	0.1
Taking other prescription medications	0.6	0.9	3.1	-0.1	0.3	-1.8	0.2	1.2	-1.3	-1.1	-0.7	-0.0
Financial difficulties in last 2 years	0.6	0.8	1.6	1.3	1.1	0.5	-0.7	0.6	0.8	0.7	1.1	1.1
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.0	1.2	-1.0	0.7	1.4	-0.9	-0.3	0.4	-0.8	-0.5
Hip circumference	0.6	2.8	6.2	-2.5	-0.5	0.2	-2.0	-1.1	-1.4	-2.3	-2.3	-0.4
Medication: Blood pressure	0.6	1.1	4.8	0.9	0.4	-2.2	0.3	1.3	0.2	-0.8	0.9	0.9
Diabetes diagnosed by doctor	0.6	1.1	4.2	-0.5	-1.0	-2.0	-1.2	0.1	-1.0	-0.8	0.3	-1.0
Medication: Gliclazide	0.6	0.6	1.8	-1.1	-0.8	-0.5	-0.8	-0.8	0.1	-0.2	-0.4	-1.4
Guilty feelings	0.6	1.0	4.3	-1.3	0.3	-0.6	1.1	2.1	0.3	0.6	0.3	0.7
Eye problems/disorders: Glaucoma	0.6	0.7	2.0	0.5	0.6	-0.7	0.7	0.5	0.7	1.0	1.4	0.9
Supplements: Fish oil (including cod liver oil)	0.6	0.7	3.0	-1.7	-0.2	0.4	-0.3	0.3	-1.0	-1.1	-0.7	-0.8
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.8	-1.3	0.7	0.8	-0.4	1.2	-0.7	-0.9	-0.8	-0.1
Age started oral contraceptive pill	0.6	0.7	1.7	0.2	0.1	1.1	-0.0	-1.0	1.3	0.2	-1.1	0.9
Unable to work because of sickness or disability	0.6	0.8	2.3	0.5	0.5	-0.9	1.4	1.5	0.3	0.3	0.8	0.8
Depression (Nagel 2018)	0.5	0.7	1.2	0.3	1.1	-1.1	-1.0	0.8	-0.4	-0.6	-0.9	0.8
Alzheimer’s Disease (in father)	0.5	0.5	1.3	-0.9	-1.1	-0.4	0.1	-0.2	-0.5	-1.1	-1.0	-0.2
Ovarian Cancer	0.5	0.7	2.5	0.0	1.0	0.6	0.2	0.3	1.6	1.2	0.4	1.0
Waist Hip Ratio (WHR)	0.5	2.1	6.1	0.8	-1.8	0.2	-1.0	-2.5	-1.4	-0.6	-1.4	-2.0
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.2	-0.7	-0.1	-1.5	-0.3	1.0	1.0	0.3	0.9	0.8
Supplements: Zinc	0.5	0.5	1.9	-0.1	0.2	1.3	0.4	-0.5	-0.1	0.0	-1.4	0.5
Diabetes (father)	0.5	0.6	1.8	0.4	1.2	0.2	-0.1	-0.2	1.2	1.3	0.2	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	5.0	-0.0	-0.7	-2.2	0.2	0.9	-0.3	0.2	1.3	-1.1
Multivitamins +/- minerals	0.5	0.7	2.2	-1.0	0.5	1.5	-0.4	1.1	-0.5	-0.3	-0.7	0.5
Waist circumference	0.5	1.9	4.1	-1.6	-0.7	0.2	-1.6	-1.5	-1.0	-1.7	-2.0	-0.6
Number of incorrect matches in round	0.5	0.9	3.0	1.7	0.7	-0.1	0.2	1.4	-0.1	0.2	1.3	0.7
Pain all over the body in last month	0.5	0.5	1.9	-0.3	0.3	0.8	1.4	-0.6	0.2	-0.0	-1.2	0.2
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	5.5	-1.4	-1.6	2.4	0.7	-1.7	-0.1	-0.0	-0.9	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	6.9	-1.7	-0.9	2.6	1.0	-1.6	0.3	0.4	-0.8	-0.4
Length of working week for main job	0.5	0.6	2.3	-0.8	0.3	-0.3	1.2	1.5	-0.7	-0.2	0.1	-0.1
Birth weight of first child	0.5	0.9	2.3	-1.3	0.1	1.0	-1.4	-1.1	-0.5	-0.3	-1.5	-0.1
Birth weight	0.5	1.2	2.9	1.7	0.7	1.2	1.3	-0.0	1.0	1.2	1.0	0.9
Forced vital capacity (FVC), Best measure	0.5	1.8	7.3	-1.6	-0.9	2.7	-0.1	-1.9	-0.2	0.2	-1.3	-0.6
Leg fat percentage (right)	0.5	1.6	5.8	-1.7	0.2	-0.2	-2.4	-0.5	-0.6	-1.9	-1.3	0.3
Worry too long after embarrassment	0.5	0.8	2.1	0.0	-1.1	0.3	-0.7	0.1	-1.3	-0.8	-1.5	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	1.9	0.1	-1.4	-0.5	-0.5	0.5	-1.2	-0.8	0.1	-1.1
Eye problems/disorders: None of the above	0.5	0.6	1.9	-0.5	0.7	-0.2	0.8	1.2	0.3	-0.2	1.4	0.4
Medication: Omeprazole	0.5	0.6	2.4	-0.1	0.4	-1.5	-0.4	1.1	-0.9	-0.8	-0.1	0.3
Family relationship satisfaction	0.5	0.7	3.1	-0.5	-0.6	-1.2	-0.1	0.8	-0.1	-0.4	1.8	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.5	0.6	-0.5	0.4	-0.2	1.2	-1.1	-0.8	-1.0	0.6
Average weekly red wine intake	0.5	0.7	2.8	0.2	-0.8	-0.2	-0.4	-0.2	-0.7	-1.7	-0.7	-1.2
Eye problems/disorders: Cataract	0.5	0.5	2.0	0.4	-0.5	0.4	-0.2	-1.4	0.5	0.5	-1.2	-0.4
Average weekly champagne plus white wine intake	0.5	0.7	2.4	0.3	-0.1	0.4	1.5	0.1	1.0	1.5	0.3	0.3
Commuting to job workplace: Public transport	0.5	0.6	1.8	-0.5	1.4	0.6	0.5	0.6	1.0	0.7	-0.1	1.0
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.1	-1.0	1.0	0.6	0.9	-0.1	0.6	0.3	-0.8	0.8
Illnesses of father: High blood pressure	0.5	0.6	1.3	1.1	1.1	0.6	0.1	1.2	0.4	0.4	1.1	0.3
Arm fat-free mass (left)	0.5	2.7	7.2	-1.4	-1.4	2.2	-1.4	-1.6	-1.3	-1.5	-2.7	-0.4
Fractured/broken bones in last 5 years	0.5	0.6	1.6	0.2	-1.3	0.1	1.1	-0.7	1.0	0.3	-1.0	0.0
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.3	-0.3	0.9	-1.1	0.1	1.5	-0.4	-0.3	0.6	0.8
Alcohol drinker status: Previous	0.5	0.6	2.4	0.3	-1.3	0.5	0.6	-0.1	-0.6	-0.1	-1.6	-0.1
Arm predicted mass (left)	0.5	2.6	8.2	-1.3	-1.1	2.2	-1.3	-1.5	-1.2	-1.4	-2.9	-0.1
Bipolar Disorder or Schizophrenia	0.4	1.1	2.7	-1.7	-0.9	-0.2	0.3	-1.2	-0.7	-1.5	-1.3	-0.4
Respiratory disease	0.4	1.0	3.2	-0.8	-0.6	0.1	1.1	-1.4	-0.7	-0.6	-0.7	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.8	-0.3	0.8	-1.3	-0.5	0.7	0.0	-0.4	-0.1	0.9
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.2	0.2	1.1	0.5	0.3	0.6	0.3	0.2	0.7	0.9
Serious illness, injury or assault to yourself	0.4	0.5	2.0	-1.4	0.3	-1.1	-0.3	0.3	0.5	0.0	0.7	-0.3
Chronic bronchitis/emphysema (father)	0.4	0.4	2.0	0.2	-0.2	0.9	-1.4	0.4	-0.9	-0.0	-0.1	-0.2
Forced vital capacity (FVC)	0.4	1.5	6.9	-0.7	-1.1	2.6	0.1	-1.9	0.0	0.3	-0.8	-0.5
Neuroticism score	0.4	0.9	5.2	-0.2	-0.3	-2.3	0.3	1.4	-0.4	0.2	0.3	-0.1
Trunk fat-free mass	0.4	2.5	8.0	-0.7	-1.4	2.3	-1.1	-1.6	-1.1	-1.2	-2.8	-0.3
Alcohol intake versus 10 years previously	0.4	0.5	3.5	0.9	-0.2	1.9	0.1	0.2	-0.1	-0.0	-0.2	0.7
Trunk predicted mass	0.4	2.4	7.8	-0.8	-1.3	2.3	-1.1	-1.6	-1.1	-1.2	-2.8	-0.3
Peak expiratory flow (PEF)	0.4	0.9	4.3	-0.7	-0.0	1.8	2.1	-0.1	0.4	0.3	-0.3	0.2
Pulse wave reflection index	0.4	0.5	1.0	-1.0	-0.2	0.8	1.0	-0.7	0.5	0.5	-0.5	-0.7
Glaucoma (self-reported)	0.4	0.4	2.0	0.3	0.4	-0.2	0.3	0.1	0.6	0.9	1.4	0.6
Arm fat-free mass (right)	0.4	2.1	6.8	-1.0	-1.0	2.4	-0.9	-1.4	-0.8	-1.0	-2.6	0.3
Shortness of breath walking on level ground	0.4	0.5	2.3	-0.4	0.5	0.6	1.5	-0.8	0.5	0.8	-0.2	0.1
Leg fat mass (right)	0.4	1.6	4.1	-1.7	0.1	0.2	-2.0	-0.6	-0.9	-1.9	-1.6	0.4
Arm predicted mass (right)	0.4	2.2	6.7	-0.9	-1.1	2.3	-1.2	-1.4	-1.0	-1.1	-2.6	0.1
Comparative height size at age 10	0.4	2.2	5.2	-2.3	-1.2	2.0	-0.1	-0.2	-1.4	-1.2	-2.1	-1.1
Had major operations	0.4	0.5	3.2	1.8	0.2	0.0	0.4	0.7	0.1	-0.0	-0.6	0.3
Whole body fat-free mass	0.4	2.3	7.2	-1.2	-1.2	2.0	-0.9	-1.5	-1.2	-1.4	-2.7	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.0	-1.0	0.8	0.6	-0.0	0.9	0.4	0.5	0.3	0.6
Whole body water mass	0.4	2.3	7.4	-1.1	-1.2	2.0	-1.0	-1.5	-1.2	-1.4	-2.7	-0.2
Alcohol drinker status: Never	0.4	0.5	2.0	0.6	0.0	0.0	0.5	0.1	0.8	1.1	1.4	-0.2
Basal metabolic rate	0.4	1.9	5.6	-1.4	-0.9	1.8	-1.1	-1.3	-1.1	-1.4	-2.4	-0.0
Leg fat percentage (left)	0.4	1.4	5.7	-1.2	0.5	-0.2	-2.4	-0.3	-0.7	-1.8	-1.0	0.3
Myopia	0.4	0.6	2.4	-0.6	0.3	-0.5	0.4	1.6	-0.1	0.1	1.5	0.0
Leg fat mass (left)	0.4	1.5	4.0	-1.5	0.2	0.3	-2.0	-0.4	-1.0	-1.9	-1.5	0.3
Intelligence (Savage-Jansen 2018)	0.3	0.9	3.0	-0.7	0.4	1.7	1.4	-0.2	0.5	1.0	-1.1	-0.2
Schizophrenia (2018)	0.3	0.7	2.8	-0.6	0.5	1.3	1.7	-0.4	0.2	0.1	-0.6	0.7
Breast Cancer	0.3	0.8	1.8	0.6	-0.2	1.2	0.8	-0.6	1.4	1.3	0.1	0.6
Fasting Glucose	0.3	0.4	1.3	-0.5	-0.5	0.3	0.8	-0.1	0.4	0.8	1.1	-0.3
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.0	-1.4	-0.7	-1.4	-0.4	0.6	-0.4	-0.1	0.6	-0.6
Chronotype (morning person)	0.3	0.7	2.5	-0.3	-0.0	-1.6	0.1	1.4	0.2	0.0	1.1	0.3
Relative age of first facial hair	0.3	0.7	2.4	1.0	-0.5	0.4	0.6	-0.0	0.3	1.5	1.3	-0.1
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	1.5	-0.5	-0.7	-1.2	-0.1	-0.0	0.3	0.0	0.7	-0.6
Leg fat-free mass (left)	0.3	1.5	3.8	-1.8	-0.8	1.1	-0.7	-0.9	-1.1	-1.6	-1.9	-0.1
Townsend deprivation index at recruitment	0.3	0.5	2.2	0.2	-0.3	-0.7	-0.4	0.6	0.5	0.5	1.5	0.5
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.6	-0.7	-0.8	-0.2	0.8	0.2	-0.4	0.0	-0.8	-0.4
Medication: Levothyroxine sodium	0.3	0.6	2.5	-0.3	-0.4	1.0	0.8	-0.7	-0.3	0.1	-1.6	-0.1
Leg predicted mass (left)	0.3	1.6	4.0	-1.8	-0.8	1.1	-0.7	-0.9	-1.2	-1.6	-2.0	-0.1
Trunk fat mass	0.3	1.1	4.0	-1.4	0.3	0.4	-2.0	-0.7	-0.4	-1.3	-1.0	0.5
Weight	0.3	1.4	2.9	-1.7	-0.2	1.2	-1.5	-0.7	-0.7	-1.5	-1.7	0.4
Arm fat percentage (right)	0.3	1.2	4.9	-1.5	0.8	-0.5	-2.2	-0.1	-0.3	-1.6	-0.6	0.5
Father’s age at death	0.3	0.4	0.8	0.5	-0.6	0.9	-0.1	-0.6	-0.5	-0.9	-0.6	-0.1
Noisy workplace	0.3	0.3	0.7	-0.7	0.6	-0.7	0.2	-0.0	-0.8	-0.7	0.3	-0.5
Impedance of arm (left)	0.3	1.5	5.2	-0.4	1.5	-1.3	0.8	1.1	1.0	1.0	2.3	0.3
Arm fat mass (right)	0.3	1.3	4.0	-1.6	0.5	0.4	-2.0	-0.6	-0.4	-1.4	-1.2	0.6
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.2	-0.3	0.4	-0.1	-0.2	0.6	-1.1	-0.0	-1.1	-0.0
Comparative body size at age 10	0.3	0.8	1.7	-0.9	1.3	-0.3	0.3	0.9	1.2	0.4	1.2	1.0
Medication: Allopurinol	0.3	0.4	1.0	-0.3	-1.0	-0.9	0.7	0.2	-0.4	-0.6	-0.6	-0.3
Whole body fat mass	0.3	1.2	3.6	-1.6	0.6	0.6	-1.9	-0.6	-0.4	-1.3	-1.2	0.7
Number of full sisters	0.3	0.4	1.3	-0.4	-0.0	-1.1	-0.4	0.9	-0.7	-0.6	-0.2	0.4
Age at last live birth	0.3	0.4	0.8	-0.4	0.8	0.6	0.7	0.3	0.5	0.8	0.9	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	3.0	-0.7	0.4	1.3	1.7	0.1	0.0	0.7	-0.2	0.2
Arm fat percentage (left)	0.3	1.1	3.5	-1.6	1.0	-0.4	-1.9	-0.1	0.0	-1.3	-0.4	0.7
Mood swings	0.3	0.5	2.1	-1.0	-0.2	-1.5	-0.1	0.3	-0.6	-0.6	-0.1	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.3	0.6	2.2	1.2	-0.8	0.3	0.3	-1.5	0.4	0.4	0.2	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.9	-1.3	-0.2	0.7	-0.6	-1.4	0.8	0.7	0.3	-0.3
Arm fat mass (left)	0.3	1.1	3.1	-1.7	0.8	0.6	-1.8	-0.4	-0.0	-1.1	-0.9	0.8
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.2	0.6	0.7	0.2	0.9	0.1	0.7	1.1	0.4	0.6
Depressed Affect (Nagel 2018)	0.2	0.4	1.6	-0.8	-0.3	-0.5	-0.5	-0.1	-0.6	-0.4	-1.3	-0.4
Neuroticism (Nagel 2018)	0.2	0.4	1.1	-0.2	-0.6	-1.1	0.1	0.8	-0.6	-0.3	-0.8	-0.1
Alzheimer’s Disease (including proxy)	0.2	0.2	0.7	0.3	-0.4	0.5	0.1	-0.8	-0.1	-0.3	-0.8	-0.2
Irritable Bowel Disease (IBD)	0.2	0.6	2.0	-1.4	-0.5	1.3	-0.8	0.0	-0.0	0.0	-0.6	-0.5
Schizophrenia (2014)	0.2	0.4	0.8	-0.8	-0.2	0.9	0.8	-0.7	-0.7	-0.7	-0.5	-0.2
Triglycerides	0.2	0.4	1.1	0.2	-0.7	-0.7	-0.7	-0.5	-0.6	-0.4	0.3	-1.1
Blood Red Count	0.2	2.3	8.7	1.3	0.0	1.1	-3.0	-1.6	-2.1	-1.2	-0.2	-0.8
BMI	0.2	1.2	4.0	-2.0	0.3	0.6	-1.1	-0.9	-0.1	-1.1	-1.7	0.5
Height	0.2	3.8	18.3	-1.6	-1.0	4.3	0.4	-1.9	-1.1	-0.5	-2.8	-0.1
Lung FEV1/FVC ratio	0.2	0.9	2.5	-1.6	-0.4	1.6	0.2	-0.4	-0.4	-0.6	-1.3	-0.5
Neuroticism	0.2	0.6	2.2	0.6	-0.2	-1.5	0.3	1.5	-0.5	0.2	-0.3	0.1
Trunk fat percentage	0.2	0.9	4.0	-1.4	0.6	-0.1	-2.0	-0.5	-0.1	-1.1	-0.4	0.5
Maternal smoking around birth	0.2	0.3	1.0	-0.4	-0.4	-0.1	-0.9	-0.1	-1.0	-0.5	-0.6	-0.5
Age when periods started (menarche)	0.2	0.6	3.8	1.9	-0.5	0.0	-0.1	-0.3	-0.4	-0.7	-0.5	-0.1
Sitting height	0.2	1.5	5.7	-0.8	-1.1	1.8	-0.8	-0.7	-1.1	-0.8	-2.4	-0.1
Body mass index (BMI)	0.2	0.8	2.0	-1.2	0.1	0.3	-1.4	-0.5	-0.3	-1.3	-1.1	0.4
Had menopause	0.2	0.3	1.1	0.7	-1.1	0.6	0.1	-0.4	-0.2	-0.0	-0.4	-0.2
Had other major operations	0.2	0.2	0.9	0.9	0.1	0.3	0.0	0.3	0.1	0.1	0.3	0.7
Impedance of arm (right)	0.2	0.9	2.7	-0.3	1.2	-1.3	0.6	0.9	0.6	0.6	1.6	0.1
Worrier / anxious feelings	0.2	0.4	1.9	0.2	-0.2	-1.1	0.6	1.4	-0.2	-0.1	0.0	0.6
Asthma	0.2	0.4	2.0	0.4	0.2	0.3	1.4	-0.9	0.2	0.2	-0.4	-0.4
Breastfed as a baby	0.2	0.2	0.7	-0.1	-0.4	-0.8	-0.2	0.7	-0.4	-0.5	-0.3	0.1
Blood clot in the leg (DVT)	0.2	0.2	0.5	0.4	0.5	0.2	0.7	0.2	0.4	0.7	0.3	0.3
Headache pain in last month	0.2	0.3	0.9	-0.7	-0.3	-0.1	-0.9	0.4	-0.9	-0.4	-0.6	-0.1
High blood pressure (siblings)	0.2	0.3	1.6	0.3	-0.1	0.2	-0.6	0.1	-0.6	-1.2	-0.5	0.1
Body fat percentage	0.2	1.0	3.6	-1.5	0.7	-0.0	-1.9	-0.4	-0.1	-1.3	-0.7	0.6
Emphysema/chronic bronchitis	0.2	0.2	0.6	-0.6	0.8	0.5	-0.1	-0.5	0.2	0.3	0.2	-0.0
Suffer from ‘nerves’	0.2	0.3	1.3	0.2	-0.1	-0.1	-0.0	-0.5	-0.1	1.1	0.6	-0.6
Chest pain or discomfort	0.2	0.2	0.6	-0.2	-0.3	-0.5	0.0	-0.3	-0.8	0.4	0.7	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.5	1.2	-0.1	0.4	-0.6	0.4	-0.4	-0.1	-0.0	0.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.8	-0.1	-0.7	-0.3	0.1	-0.4	-0.9	-0.3	-0.1	-0.6
Knee pain experienced in last month	0.2	0.3	1.2	0.6	0.3	-1.1	0.8	0.7	0.1	-0.0	0.2	0.3
Leg fat-free mass (right)	0.2	1.3	3.2	-1.4	-0.6	1.1	-0.6	-0.6	-1.2	-1.5	-1.8	-0.0
Friendships satisfaction	0.2	0.2	0.5	0.4	-0.4	-0.4	0.7	0.1	0.5	0.2	0.7	0.4
Breast cancer (self-reported)	0.2	0.2	0.6	-0.1	0.4	0.6	0.4	0.7	0.2	0.3	0.8	0.4
Asthma (self-reported)	0.2	0.4	1.4	0.2	-0.2	0.3	1.2	-1.2	-0.1	-0.0	-0.8	-0.7
Leg predicted mass (right)	0.2	1.2	3.0	-1.4	-0.6	1.1	-0.5	-0.7	-1.1	-1.4	-1.7	-0.0
Average weekly beer plus cider intake	0.2	0.3	1.1	-0.1	-0.5	-0.4	0.3	-0.9	-0.1	-0.1	0.8	-1.0
Irritability	0.2	0.4	1.1	-0.7	-0.4	-1.0	0.6	0.9	-0.3	-0.1	0.7	-0.4
Impedance of whole body	0.2	0.9	3.1	0.6	1.0	-0.5	0.7	0.5	1.0	1.4	1.8	0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.4	1.1	-0.2	-0.2	0.5	-0.1	-0.9	0.0	-0.1	-1.0	-1.0
Age at First Birth	0.1	0.2	0.9	-0.2	0.2	-1.0	-0.3	-0.3	0.0	-0.7	0.3	-0.0
Body Mass Index (BMI) (2010)	0.1	0.1	0.4	-0.2	-0.3	0.4	-0.0	0.3	-0.0	-0.3	-0.7	0.2
Blood White Count	0.1	1.0	2.5	0.7	-0.7	-0.0	-1.3	-1.6	-0.6	-1.2	-1.2	-0.6
Hair Pigment	0.1	3.6	11.6	-1.0	1.8	-3.4	-1.1	0.9	1.1	0.6	3.1	1.8
Tanning	0.1	1.5	7.3	-0.0	-1.0	1.4	1.0	-1.2	-0.5	-0.4	-2.7	-0.8
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.6	0.3	-0.8	0.7	0.1	-0.5	-0.0	0.3	-0.3	0.1
Impedance of leg (right)	0.1	0.4	2.2	0.4	0.3	0.4	0.3	-0.3	0.9	1.5	0.5	0.2
Stomach or abdominal pain in last month	0.1	0.1	0.3	0.5	0.5	-0.2	0.1	0.1	0.1	0.3	0.6	0.1
Impedance of leg (left)	0.1	0.6	2.0	1.2	0.6	0.4	0.3	-0.1	0.8	1.4	0.9	0.1
Fluid intelligence score	0.1	0.2	0.5	0.1	0.7	0.6	0.6	0.2	0.5	0.4	-0.4	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.9	-0.8	0.5	-0.5	0.2	0.1	-0.1	-0.2	-1.0	0.1
Happiness	0.1	0.2	1.0	0.1	0.2	0.3	-0.0	1.0	0.0	0.2	0.4	0.3
Medication: Lansoprazole	0.1	0.1	0.6	-0.3	0.0	-0.8	-0.2	-0.2	0.4	-0.2	0.3	0.5
Lung cancer (father)	0.1	0.1	0.6	-0.1	0.3	0.8	0.0	-0.5	0.2	0.2	-0.2	0.3
Standing height	0.1	1.3	5.8	-1.2	-0.8	2.4	-0.2	-0.8	-0.9	-0.3	-1.7	-0.0
Gout (self-reported)	0.1	0.1	0.3	-0.1	-0.3	0.3	0.5	0.1	0.2	-0.3	-0.0	0.3
Number of full brothers	0.1	0.1	0.3	0.0	0.4	0.5	0.6	0.2	0.3	0.4	-0.2	0.3
Wheeze or whistling in the chest in last year	0.1	0.1	0.5	0.2	0.2	0.2	-0.1	0.7	-0.1	0.3	0.0	0.6
Health satisfaction	0.1	0.1	0.4	-0.2	0.4	-0.1	0.3	0.1	0.6	0.4	0.1	0.2
Neck or shoulder pain in last month	0.1	0.2	0.8	-0.9	-0.0	-0.2	0.2	-0.2	-0.5	0.1	-0.2	-0.7
Alcohol intake frequency.	0.1	0.2	0.8	0.3	-0.9	0.2	-0.2	-0.3	-0.6	-0.0	0.2	-0.6
Long-standing illness, disability or infirmity	0.1	0.2	0.6	-0.3	-0.2	-0.0	0.4	0.2	-0.7	-0.4	-0.6	-0.0

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