Best TWAS P=1.45e-14 · Best GWAS P=1.81e-14 conditioned to 0.0435
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PLD1 | 0.27 | 0.21 | lasso | 8 | 0.18 | 3.6e-10 | 6.3 | -6.4 | 1.5e-10 | -0.69 | 0.97 | 0.03 | FALSE |
| 2 | GTEx | Spleen | PLD1 | 0.70 | 0.42 | enet | 30 | 0.60 | 3.3e-19 | 7.4 | -7.7 | 1.5e-14 | -0.86 | 0.02 | 0.98 | TRUE |
| 3 | GTEx | Stomach | PLD1 | 0.17 | 0.03 | enet | 14 | 0.02 | 4.0e-02 | 7.2 | -5.5 | 3.1e-08 | -0.73 | 0.06 | 0.59 | FALSE |
| 4 | GTEx | Thyroid | PLD1 | 0.09 | 0.08 | enet | 10 | 0.07 | 3.4e-06 | -4.7 | -7.0 | 1.9e-12 | -0.81 | 0.09 | 0.91 | FALSE |