Best TWAS P=4.1e-14 · Best GWAS P=3.14e-13 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ABCF3 | 0.05 | 0.00 | blup | 494 | 0.01 | 1.6e-02 | -1.2 | 5.4 | 6.4e-08 | 0.52 | 0.12 | 0.13 | FALSE |
| 2 | GTEx | Brain Cerebellum | ABCC5 | 0.18 | 0.18 | lasso | 5 | 0.13 | 1.4e-04 | 4.7 | 5.3 | 1.1e-07 | 0.65 | 0.21 | 0.42 | FALSE |
| 3 | GTEx | Esophagus Mucosa | ABCC5 | 0.13 | 0.10 | lasso | 5 | 0.09 | 1.8e-06 | -5.8 | -5.8 | 6.0e-09 | -0.82 | 0.42 | 0.58 | FALSE |
| 4 | GTEx | Whole Blood | ABCC5 | 0.10 | 0.08 | lasso | 4 | 0.08 | 9.9e-08 | 7.3 | -7.3 | 2.6e-13 | -0.97 | 0.00 | 1.00 | FALSE |
| 5 | NTR | Blood | ABCC5 | 0.08 | 0.11 | enet | 26 | 0.11 | 6.8e-33 | 7.3 | -7.6 | 4.1e-14 | -0.95 | 0.00 | 1.00 | TRUE |
| 6 | YFS | Blood | ABCC5 | 0.25 | 0.37 | enet | 48 | 0.42 | 8.9e-154 | 7.3 | -7.2 | 7.6e-13 | -0.93 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ABCC5 | 0.04 | 0.03 | enet | 9 | 0.03 | 5.5e-04 | 5.6 | -6.3 | 2.7e-10 | -0.69 | 0.42 | 0.33 | FALSE |