[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr3:193,664,025-195,106,167

Best TWAS P=1.29e-10 · Best GWAS P=4.79e-10 conditioned to 0.0624

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	LSG1	0.49	0.41	lasso	6	0.41	4.0e-36	5.4	5.6	1.7e-08	-0.38	0.28	0.72	FALSE
2	GTEx	Adrenal Gland	LSG1	0.21	0.13	lasso	4	0.04	1.8e-02	5.4	5.2	2.3e-07	-0.33	0.17	0.48	FALSE
3	GTEx	Artery Aorta	LSG1	0.52	0.35	lasso	6	0.34	2.3e-19	5.4	5.2	2.6e-07	-0.31	0.28	0.72	FALSE
4	GTEx	Artery Coronary	LSG1	0.40	0.29	lasso	5	0.30	6.9e-11	5.4	5.6	1.7e-08	-0.48	0.28	0.71	FALSE
5	GTEx	Artery Tibial	LSG1	0.47	0.40	lasso	4	0.40	4.1e-33	5.4	5.4	8.5e-08	-0.34	0.28	0.72	FALSE
6	GTEx	Brain Cerebellar Hemisphere	LSG1	0.69	0.55	lasso	5	0.55	1.1e-16	5.4	5.7	1.4e-08	-0.44	0.28	0.72	FALSE
7	GTEx	Brain Cerebellum	LSG1	0.80	0.56	lasso	12	0.56	6.8e-20	5.4	5.5	3.0e-08	-0.42	0.28	0.72	FALSE
8	GTEx	Breast Mammary Tissue	LSG1	0.50	0.41	lasso	4	0.42	2.9e-23	5.4	5.8	8.4e-09	-0.38	0.28	0.72	FALSE
9	GTEx	Breast Mammary Tissue (Male)	LSG1	0.16	0.03	lasso	2	0.04	5.0e-02	5.4	5.4	6.7e-08	-0.35	0.08	0.24	FALSE
10	GTEx	Breast Mammary Tissue (Female)	LSG1	0.46	0.30	lasso	5	0.28	5.4e-09	5.4	5.5	3.9e-08	-0.33	0.21	0.76	FALSE
11	GTEx	Colon Transverse	LSG1	0.43	0.30	lasso	5	0.29	3.0e-14	5.4	6.0	1.8e-09	-0.44	0.27	0.73	FALSE
12	GTEx	Esophagus Mucosa	LSG1	0.46	0.33	lasso	9	0.33	1.8e-22	5.4	5.4	5.4e-08	-0.37	0.28	0.72	FALSE
13	GTEx	Esophagus Muscularis	LSG1	0.60	0.44	lasso	5	0.45	1.1e-29	5.4	5.8	6.1e-09	-0.44	0.28	0.72	FALSE
14	GTEx	Heart Atrial Appendage	LSG1	0.28	0.28	enet	6	0.29	1.7e-13	5.4	5.6	2.0e-08	-0.39	0.27	0.73	FALSE
15	GTEx	Lung	LSG1	0.49	0.40	lasso	2	0.40	2.9e-32	5.4	5.4	6.7e-08	-0.35	0.28	0.72	FALSE
16	GTEx	Nerve Tibial	LSG1	0.66	0.56	lasso	7	0.55	1.6e-46	5.4	5.4	8.3e-08	-0.36	0.28	0.72	FALSE
17	GTEx	Pituitary	LSG1	0.63	0.42	lasso	8	0.39	6.1e-11	5.4	6.3	2.7e-10	-0.58	0.24	0.75	FALSE
18	GTEx	Prostate	LSG1	0.78	0.47	lasso	18	0.44	2.6e-12	5.4	5.6	1.9e-08	-0.38	0.28	0.72	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	LSG1	0.36	0.27	lasso	4	0.25	5.2e-14	5.4	5.3	1.2e-07	-0.34	0.28	0.72	FALSE
20	GTEx	Skin Sun Exposed Lower leg	LSG1	0.20	0.12	lasso	2	0.10	1.4e-08	5.4	5.4	6.7e-08	-0.35	0.28	0.72	FALSE
21	GTEx	Stomach	LSG1	0.47	0.27	lasso	5	0.28	6.7e-14	5.4	5.3	9.5e-08	-0.36	0.28	0.72	FALSE
22	GTEx	Testis	LSG1	0.64	0.43	lasso	7	0.44	1.3e-21	5.4	5.1	3.1e-07	-0.41	0.28	0.72	FALSE
23	GTEx	Thyroid	LSG1	0.73	0.54	enet	39	0.55	4.8e-50	5.4	5.5	3.1e-08	-0.45	0.28	0.72	FALSE
24	GTEx	Uterus	LSG1	0.69	0.42	lasso	6	0.35	5.9e-08	5.4	5.4	6.3e-08	-0.35	0.24	0.66	FALSE
25	GTEx	Whole Blood	FAM43A	0.12	0.03	lasso	6	0.03	1.2e-03	-6.2	5.6	2.0e-08	-0.86	0.01	0.99	FALSE
26	METSIM	Adipose	LSG1	0.30	0.27	lasso	2	0.27	7.6e-40	5.4	5.4	6.6e-08	-0.35	0.28	0.72	FALSE
27	NTR	Blood	FAM43A	0.06	0.04	lasso	3	0.04	4.3e-14	-6.1	6.1	1.4e-09	-0.89	0.00	1.00	FALSE
28	NTR	Blood	LSG1	0.15	0.11	lasso	2	0.11	7.9e-34	5.4	5.4	6.6e-08	-0.35	0.28	0.72	FALSE
29	YFS	Blood	FAM43A	0.30	0.15	enet	77	0.20	2.4e-64	-6.1	6.4	1.3e-10	-0.79	0.00	1.00	TRUE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	LSG1	0.15	0.08	lasso	4	0.08	1.6e-09	4.3	5.2	1.8e-07	-0.69	0.89	0.11	FALSE
31	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LSG1	0.05	0.05	lasso	3	0.04	1.0e-05	5.4	5.4	7.6e-08	-0.35	0.24	0.62	FALSE