Hub : Genes

FAM43A

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Brain Cerebellar Hemisphere 0.5230 0.1480 1.3e-03 0.051 NA 0.038 NA 0.032 1.9e-02 NA 3.9e-02 NA 5.2e-02
2 GTEx Cells Transformed fibroblasts 0.1120 0.0460 7.3e-03 0.000 NA -0.003 NA -0.001 3.3e-01 NA 5.9e-01 NA 4.3e-01
3 GTEx Colon Sigmoid 0.4680 0.1190 1.9e-03 -0.008 NA -0.008 NA -0.005 8.9e-01 NA 9.8e-01 NA 5.3e-01
4 GTEx Esophagus Muscularis 0.2090 0.0740 8.8e-03 -0.005 NA -0.001 NA -0.004 9.7e-01 NA 4.0e-01 NA 7.1e-01
5 GTEx Whole Blood 0.1220 0.0400 3.3e-04 0.035 NA 0.023 NA 0.028 3.3e-04 NA 3.3e-03 NA 1.2e-03
6 NTR Blood 0.0641 0.0160 2.7e-07 0.044 0.024 0.039 0.040 0.044 5.5e-14 1.8e-08 1.7e-12 6.0e-13 4.3e-14
7 YFS Blood 0.2986 0.0309 0.0e+00 0.153 0.180 0.203 0.164 0.178 9.7e-48 2.1e-56 2.4e-64 2.6e-51 4.8e-56
8 TCGA Cervical Squamous Cell Carcinoma 0.1470 0.0690 1.6e-03 0.015 0.016 0.025 NA 0.013 5.7e-02 5.0e-02 2.2e-02 NA 7.2e-02
9 TCGA Stomach Adenocarcinoma 0.0910 0.0490 1.9e-03 -0.004 0.030 0.033 NA 0.001 8.1e-01 2.7e-03 1.8e-03 NA 2.5e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.5 0.7 1.7 0.7 -0.9 1.3 0.0 -0.2 -0.5 -1.3 0.0 1.3
Bipolar Disorder or Schizophrenia 0.3 0.8 3.1 -0.2 -0.7 1.8 0.0 -0.7 -0.7 -1.3 -0.1 -1.1
Depressed Affect (Nagel 2018) 0.5 1.1 2.8 -1.7 -0.5 1.3 0.0 -1.0 -0.9 -0.5 -0.9 -1.4
Depression (Nagel 2018) 0.3 0.5 2.3 1.5 0.3 -0.8 0.0 0.3 0.1 0.3 -0.7 -0.5
Intelligence (Savage-Jansen 2018) 0.2 0.6 2.3 1.2 -1.3 -0.2 0.0 0.4 -0.3 -0.3 -1.5 -0.2
Neuroticism (Nagel 2018) 0.4 1.0 3.2 -1.5 -0.5 -0.2 0.0 -1.4 -1.8 -0.7 -0.3 -0.6
Schizophrenia (2018) 0.5 1.1 6.0 -1.0 -0.2 1.4 0.0 -0.8 -0.5 -0.5 0.1 -2.5
Schizophrenia vs Biploar Disorder 0.6 0.8 2.6 -1.6 0.7 1.6 0.0 -0.3 -0.0 0.8 0.0 -1.0
Worry (Nagel 2018) 0.3 0.7 2.7 -0.4 -1.6 -1.0 0.0 -0.7 -1.1 -0.1 -0.2 0.8
Alzheimer’s Disease (in mother) 0.8 0.9 4.0 2.0 -0.8 -0.7 0.0 0.2 -0.1 0.4 -1.2 1.2
Alzheimer’s Disease (in father) 0.8 0.9 3.6 -1.9 -0.5 -0.0 0.0 -0.1 -0.1 1.0 1.4 -1.0
Alzheimer’s Disease (including proxy) 0.2 0.3 0.7 -0.1 -0.8 -0.5 0.0 -0.2 -0.3 0.8 -0.2 -0.8
Crohns Disease (2017) 0.2 0.4 1.2 -0.6 -0.3 0.8 0.0 0.9 0.9 1.1 -0.1 -0.2
Irritable Bowel Disease (IBD) 0.1 0.3 1.3 -1.1 0.6 0.7 0.0 -0.3 -0.3 0.1 -0.5 0.1
Ulcerative Colitis (UC) 0.7 1.4 3.5 -1.9 1.1 0.6 0.0 -1.6 -1.4 -1.2 -1.3 -0.2
Major Depression (MDD) 0.2 0.2 0.6 -0.1 -0.5 0.7 0.0 0.1 0.1 0.6 0.7 0.1
Reaction Time 0.2 0.4 2.6 0.6 -0.1 1.6 0.0 0.5 -0.0 0.4 0.7 0.3
Verbal and Numeric Reasoning (VNR) 0.4 1.0 2.9 1.2 -0.4 -0.0 0.0 1.7 1.2 1.1 -1.3 -0.4
Breast Cancer 0.3 0.7 2.9 0.1 0.3 -0.3 0.0 -0.9 -0.8 -1.3 -0.5 1.7
Ovarian Cancer 0.4 0.6 3.0 1.7 -0.6 -1.1 0.0 0.2 0.2 0.1 -0.3 0.7
Prostate Cancer 0.9 1.3 5.5 -1.2 -1.7 0.7 0.0 -0.5 0.6 1.0 -0.3 -2.3
Age at First Birth 0.8 1.2 3.4 1.8 -0.4 -1.8 0.0 1.4 1.2 0.0 -0.5 -0.3
Bipolar Disorder (2011) 0.1 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1
Body Mass Index (BMI) (2010) 0.9 1.2 5.3 1.7 2.3 -0.4 0.0 0.9 0.7 0.4 0.3 0.8
Coronary Artery Disease (CAD) 0.3 0.4 1.8 0.4 -1.4 -0.9 0.0 -0.3 -0.2 -0.2 0.3 -0.5
Crohns Disease (2012) 0.5 0.8 3.9 -0.4 -0.5 2.0 0.0 -0.6 -0.9 -1.2 0.0 0.6
Mean Putamen Volume 0.2 0.3 0.9 -0.4 0.9 -0.7 0.0 0.1 0.1 -0.1 -0.4 -0.9
Fasting Glucose 0.7 0.8 2.7 0.2 1.6 1.2 0.0 -0.6 0.1 -0.5 -0.8 1.4
HbA1C 0.5 0.5 2.1 1.2 -0.7 -0.1 0.0 0.6 0.6 0.2 -1.5 0.4
HDL Cholesterol 1.5 2.6 6.5 -2.5 -1.4 2.3 0.0 -2.0 -1.7 -1.3 -0.2 -0.9
LDL Cholesterol 0.5 0.7 2.9 -0.1 1.7 -0.4 0.0 0.8 1.0 0.9 -0.7 -0.7
Lupus 0.1 0.2 0.8 0.4 -0.7 -0.4 0.0 0.2 -0.5 0.0 -0.3 0.9
Neuroticism (2016) 0.6 0.8 2.2 -1.5 -0.9 -0.0 0.0 -1.3 -1.1 -1.1 0.6 0.2
Primary Biliary Cirrhosis 0.4 0.5 1.4 -1.2 -0.8 1.0 0.0 -1.0 -0.7 -0.1 -0.5 0.4
Rheumatoid Arthritis 1.2 1.7 3.7 1.3 -0.5 1.4 0.0 1.7 1.5 0.3 -1.9 1.4
Schizophrenia (2014) 0.9 2.0 4.9 -1.6 -0.6 1.0 0.0 -1.7 -1.4 -1.8 -0.8 -2.2
Triglycerides 0.3 0.4 1.3 1.0 0.9 -0.1 0.0 0.4 -0.1 -0.2 -1.1 -0.7
Type 2 Diabetes (T2D) (2012) 0.3 0.3 1.3 -0.2 0.5 -1.2 0.0 0.1 -0.4 0.9 0.0 0.7
Ulcerative Colitis 1.3 1.8 4.9 -1.0 0.0 1.1 0.0 -2.2 -2.2 -2.1 -0.1 0.4
Blood Eosinophil Count 1.9 14.8 41.3 3.2 -1.1 2.2 0.0 5.6 6.1 6.4 2.6 0.3
Blood Platelet Count 0.3 3.7 20.4 0.9 1.0 -4.5 0.0 2.0 1.8 0.6 -1.6 1.1
Blood Red Count 0.3 2.8 16.9 -0.5 0.8 -4.1 0.0 -0.7 -0.1 1.7 0.1 -2.0
Blood White Count 0.9 6.8 18.3 -3.0 -0.7 1.4 0.0 -3.8 -3.5 -4.3 -0.7 -2.0
Heel T-Score 0.1 0.4 1.1 1.0 -0.1 0.4 0.0 0.8 0.8 -0.3 0.2 1.1
BMI 0.9 5.4 13.3 0.6 3.6 -0.7 0.0 2.4 3.3 3.0 3.0 0.3
Height 0.1 1.2 6.4 0.2 1.0 1.0 0.0 1.0 0.9 2.5 0.6 -0.1
Waist Hip Ratio (WHR) 0.2 0.9 3.5 0.2 -1.9 1.0 0.0 1.1 0.8 0.8 -0.6 -0.9
Systolic Blood Pressure 0.4 2.0 8.1 -1.4 -2.9 -0.7 0.0 -1.3 -0.8 -1.2 0.4 -1.9
Smoking Status 0.4 1.1 3.1 1.2 -1.4 1.0 0.0 0.8 0.5 0.2 1.8 1.0
Allergy or Eczema 0.6 1.5 4.8 0.7 1.0 1.6 0.0 0.6 0.2 0.8 1.9 2.2
Cardiovascular Disease 0.8 2.8 6.5 -2.1 -1.7 -2.6 0.0 -1.8 -1.1 -0.2 1.2 -2.2
Hypothyroidism (self reported) 0.1 0.3 0.7 0.9 -0.5 0.7 0.0 0.5 0.5 0.1 -0.2 0.7
Respiratory disease 0.2 0.5 1.4 -0.0 -0.7 -1.1 0.0 0.2 -0.1 1.2 0.9 -0.5
Type 2 Diabetes (T2D) (2018) 0.3 0.5 1.5 -1.2 -0.7 -0.4 0.0 -0.4 0.0 0.0 -1.0 -0.9
Lung FEV1/FVC ratio 0.3 1.4 10.0 -0.3 1.0 -0.4 0.0 -0.7 -0.9 -0.4 -0.6 3.2
Lung FVC 0.6 3.1 9.7 -0.4 -1.1 1.4 0.0 -2.4 -2.2 -3.1 -1.7 -1.2
Neuroticism 0.2 0.4 1.3 -1.1 -0.7 -0.6 0.0 -0.5 -0.9 0.1 -0.1 0.5
Chronotype (morning person) 0.2 0.5 1.3 -1.1 -1.1 1.0 0.0 -0.4 -0.4 -0.6 -0.7 0.1
Hair Pigment 0.0 0.9 3.3 -0.4 0.1 1.8 0.0 1.2 1.5 0.5 0.4 -0.3
Tanning 0.0 0.3 1.5 0.7 1.2 0.4 0.0 -0.2 -0.4 -0.1 -0.6 0.6
Hand grip strength (left) 0.1 0.3 1.2 0.5 1.1 -0.2 0.0 0.6 0.5 1.0 -0.1 -0.1
Number of treatments/medications taken 1.0 1.8 4.0 -1.4 -0.8 0.9 0.0 -2.0 -1.9 -1.6 0.4 -1.6
Average weekly spirits intake 0.6 0.8 2.3 -1.5 -1.5 -1.0 0.0 -1.0 -0.5 0.3 0.6 -0.3
Sensitivity / hurt feelings 0.3 0.5 1.6 -0.1 1.0 -1.3 0.0 -0.5 -0.4 -0.8 -0.1 0.7
Frequency of depressed mood in last 2 weeks 0.3 0.5 1.1 0.2 1.0 -1.0 0.0 -0.8 -1.0 -0.4 -0.5 -0.3
Hearing difficulty/problems: Yes 1.0 1.5 7.2 2.7 -0.5 0.3 0.0 1.3 0.8 0.3 0.1 1.9
Relative age of first facial hair 0.8 1.7 4.8 -0.8 -0.5 1.4 0.0 -1.5 -1.2 -1.9 -2.2 -0.7
Other serious medical condition/disability diagnosed by doctor 1.1 1.4 4.8 -0.3 -2.2 1.0 0.0 0.8 0.7 0.3 -1.1 -2.0
Ever used hormone-replacement therapy (HRT) 0.6 0.7 2.1 -1.4 0.2 -0.9 0.0 -0.5 -0.2 0.3 1.4 -1.0
Ever had hysterectomy (womb removed) 0.6 0.7 2.5 -1.3 -1.6 0.4 0.0 -0.3 -0.3 -0.6 0.5 0.9
Systolic blood pressure, automated reading 0.2 0.4 2.6 -0.9 0.4 0.1 0.0 -0.4 0.1 -0.3 0.1 -1.6
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 1.2 -0.5 0.7 -0.0 0.0 -0.1 -0.2 0.1 1.1 0.2
Angina 0.3 0.4 1.6 -0.1 -0.3 0.6 0.0 0.6 1.0 1.3 0.4 0.4
Medication for hormone replacement therapy 0.9 1.1 5.1 -0.4 0.6 -0.5 0.0 -0.1 0.4 0.8 1.7 -2.3
Vitamin and mineral supplements 0.6 0.8 2.4 -1.3 -1.6 -0.9 0.0 0.1 0.5 0.7 -0.9 -0.5
Supplements: Zinc 1.9 2.1 7.7 2.8 1.0 0.6 0.0 1.4 1.0 -0.5 -0.4 2.4
Medication: Co-codamol 0.7 0.8 2.6 0.9 -1.3 1.6 0.0 0.6 0.6 0.7 0.1 0.9
Medication: Metformin 0.2 0.3 1.8 0.2 -1.1 0.4 0.0 -0.2 0.0 0.0 -1.3 0.1
Diabetes (father) 0.6 0.7 2.2 -0.3 -0.9 0.5 0.0 -0.3 -0.7 0.4 -1.5 -1.4
Diabetes (mother) 1.3 1.6 6.8 -2.6 1.7 0.7 0.0 -1.5 -0.9 -0.4 0.5 -1.1
Severe depression (siblings) 0.7 0.8 3.5 1.2 0.6 1.4 0.0 0.1 0.1 -0.3 0.1 1.9
Pack years adult smoking proportion 0.6 1.0 4.2 -1.2 0.1 0.2 0.0 -0.7 -0.4 -2.0 -0.8 -1.4
Impedance of leg (right) 0.4 1.8 4.8 -0.1 -2.2 -1.0 0.0 -1.4 -2.1 -1.9 -0.4 -0.2
Leg fat-free mass (left) 0.7 3.8 9.4 0.6 3.1 0.9 0.0 2.3 2.7 3.0 1.5 -0.2
Trunk fat percentage 0.7 2.9 8.2 0.6 2.7 0.7 0.0 2.2 2.9 2.2 -0.0 -0.4
Hand grip strength (right) 0.2 0.5 3.9 0.4 2.0 -0.2 0.0 0.3 -0.1 0.4 0.6 0.2
Townsend deprivation index at recruitment 0.2 0.3 1.1 0.8 0.2 0.8 0.0 0.6 0.3 0.2 -0.4 -1.1
Current tobacco smoking 1.0 1.6 3.7 1.3 -1.3 1.9 0.0 1.7 1.8 1.2 0.1 -0.0
Average weekly fortified wine intake 0.3 0.3 1.5 -0.5 -0.7 0.1 0.0 -0.6 -0.2 -0.6 -1.2 0.1
Maternal smoking around birth 0.4 0.6 2.6 -1.1 1.6 1.1 0.0 -0.2 0.5 0.2 0.3 -0.6
Fed-up feelings 1.0 1.8 6.2 -2.5 -0.9 -0.5 0.0 -1.3 -1.1 -0.6 -1.5 -1.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 0.7 0.6 0.7 -0.1 0.0 0.0 -0.1 -0.1 -0.8 0.8
Relative age voice broke 0.3 0.4 1.4 0.0 -0.9 0.2 0.0 0.2 0.6 -0.3 -1.2 -0.9
Taking other prescription medications 0.8 1.3 3.4 -1.2 -0.8 0.5 0.0 -1.8 -1.6 -1.1 -0.0 -1.5
Age when periods started (menarche) 0.5 1.1 4.2 0.3 1.1 -0.8 0.0 1.4 0.8 1.1 -2.1 -0.1
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 2.8 -1.1 1.7 -0.1 0.0 -0.1 -0.2 -0.9 0.4 -0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 2.7 1.6 0.7 -0.2 0.0 0.3 -0.2 -0.3 1.2 1.5
Tinnitus: Yes, but not now, but have in the past 1.6 1.7 4.3 -2.1 -1.0 1.5 0.0 -1.8 -1.8 -0.0 -0.0 1.1
Qualifications: CSEs or equivalent 0.2 0.3 0.9 0.1 -0.6 0.9 0.0 -0.4 -0.5 0.6 0.9 -0.1
Serious illness, injury or assault to yourself 0.5 0.6 2.7 -0.5 -1.0 -0.0 0.0 0.7 0.6 0.8 -1.6 -0.4
High blood pressure 0.8 2.3 5.3 -2.3 -1.3 -1.9 0.0 -1.8 -1.0 -1.1 0.6 -2.0
Hayfever, allergic rhinitis or eczema 0.3 0.7 2.4 0.4 0.8 0.7 0.0 0.6 0.3 1.6 1.2 0.5
Multivitamins +/- minerals 0.7 0.9 5.4 1.1 2.3 -0.1 0.0 0.0 -0.4 -0.9 0.7 0.7
Stomach or abdominal pain in last month 1.0 1.3 6.2 -0.3 -0.9 2.5 0.0 -0.6 -0.5 -1.1 -0.5 -1.5
Supplements: Glucosamine 0.6 0.8 5.5 0.3 2.3 -0.8 0.0 -0.1 -0.2 0.4 0.6 0.5
Diverticular disease/diverticulitis (self-reported) 0.6 0.8 1.4 1.1 -1.0 -1.0 0.0 1.1 0.9 1.2 0.2 0.4
Medication: Atenolol 0.3 0.4 1.2 0.1 -0.3 0.6 0.0 0.2 0.6 0.9 1.1 0.6
Medication: Levothyroxine sodium 0.2 0.3 2.0 0.2 -0.5 0.0 0.0 -0.2 -0.1 -0.2 -0.3 -1.4
Sitting height 0.2 1.5 4.5 0.6 2.1 -0.2 0.0 1.7 1.3 2.0 -0.3 -0.7
Chronic bronchitis/emphysema (father) 0.9 1.0 4.8 -1.5 -1.0 2.2 0.0 -0.4 0.0 -0.2 -0.4 -0.7
High blood pressure (mother) 0.3 0.4 1.6 -0.8 0.8 -1.3 0.0 -0.2 -0.2 0.1 0.0 -0.8
Body mass index (BMI) 0.5 1.9 5.9 0.3 2.4 0.0 0.0 1.7 2.4 1.5 0.8 -0.1
Impedance of leg (left) 0.3 1.6 4.1 -0.0 -2.0 -0.7 0.0 -1.0 -1.8 -1.8 -1.4 0.1
Leg predicted mass (left) 0.7 3.8 9.9 0.6 3.1 1.0 0.0 2.2 2.7 3.0 1.5 -0.2
Trunk fat mass 0.8 3.5 9.2 0.5 3.0 0.5 0.0 2.4 3.0 2.6 0.3 -0.5
Waist circumference 0.5 1.7 4.1 0.2 1.8 0.1 0.0 1.7 2.0 1.9 0.8 -0.4
Number of incorrect matches in round 1.5 2.5 8.1 -1.9 -0.4 0.0 0.0 -2.9 -2.4 -1.4 0.7 -1.7
Past tobacco smoking 0.2 0.4 1.7 -0.3 1.3 -0.3 0.0 0.3 0.6 0.2 -1.2 -0.0
Alcohol usually taken with meals 1.2 2.0 5.6 1.5 0.4 0.3 0.0 2.1 2.0 2.4 -0.6 0.7
Nervous feelings 0.4 0.7 2.1 -0.8 -1.1 -1.5 0.0 0.4 0.4 1.4 0.5 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 1.7 0.2 0.8 -0.1 0.0 -0.4 -0.5 -0.1 -0.2 1.3
Hearing difficulty/problems with background noise 2.1 3.3 7.0 2.6 -1.9 -1.9 0.0 2.6 2.1 1.4 -1.2 1.2
Hair/balding pattern: Pattern 2 0.7 0.9 2.3 1.5 1.0 0.4 0.0 1.1 0.3 0.9 1.4 0.7
Had menopause 0.8 1.0 4.1 -0.3 0.5 -0.3 0.0 0.6 0.9 0.6 -2.0 -1.6
Had other major operations 0.7 0.9 5.0 -0.5 0.4 2.2 0.0 0.9 0.7 0.8 0.5 -0.5
Forced vital capacity (FVC) 0.1 0.5 2.3 0.1 0.3 1.5 0.0 -0.8 -1.0 -0.6 -0.5 -0.3
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.8 3.2 1.8 0.8 0.1 0.0 0.9 0.4 0.2 0.2 1.5
Ever unenthusiastic/disinterested for a whole week 1.2 1.4 4.2 -1.0 0.7 1.7 0.0 1.3 1.1 2.1 1.0 -0.6
Qualifications: None of the above 0.2 0.5 1.4 1.2 -0.0 -1.2 0.0 0.7 0.5 0.2 0.9 0.6
Financial difficulties in last 2 years 1.7 2.3 6.6 0.5 -1.2 -0.6 0.0 2.5 2.6 2.0 -0.7 -0.9
Mouth/teeth dental problems 0.2 0.3 1.0 -0.1 0.3 0.1 0.0 0.6 0.2 1.0 0.9 -0.4
Heart attack 0.3 0.4 2.6 0.2 0.1 -1.6 0.0 -0.2 0.2 -1.0 -0.3 -0.2
Allergy 0.3 0.7 2.4 -1.2 0.3 0.9 0.0 -1.1 -0.5 -1.6 -0.6 -0.0
Pain all over the body in last month 1.8 2.0 5.5 0.2 -0.6 0.4 0.0 1.9 1.7 2.3 2.0 1.1
Diabetes (self-reported) 0.6 0.9 3.1 -0.9 -1.8 0.8 0.0 -0.3 0.2 0.3 -1.4 -1.0
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 2.4 -0.2 1.5 0.5 0.0 0.1 -0.5 0.8 0.6 -0.3
Medication: Ramipril 1.0 1.3 4.6 1.2 -0.1 0.7 0.0 2.1 2.1 1.0 -0.2 -0.2
Medication: Simvastatin 0.7 1.0 4.0 -1.1 -0.7 -0.3 0.0 -0.5 0.0 0.5 2.0 -1.7
Fluid intelligence score 0.4 0.9 2.5 0.9 0.2 0.2 0.0 1.0 1.0 0.6 -1.6 -1.5
Illnesses of siblings 0.9 1.2 3.9 0.6 0.4 0.3 0.0 -1.4 -2.0 -1.9 -0.5 0.7
Neuroticism score 0.3 0.7 3.3 -1.8 -0.6 -0.8 0.0 -0.9 -1.0 -0.0 0.2 0.1
Weight 0.7 3.5 11.2 0.4 3.3 0.2 0.0 2.2 2.7 2.6 1.1 -0.3
Impedance of arm (right) 0.1 0.4 3.5 -0.1 -0.6 1.9 0.0 -0.2 -0.0 0.1 -0.2 -0.0
Arm fat percentage (right) 0.7 3.0 10.2 0.5 2.1 0.7 0.0 2.3 3.2 2.5 0.1 -0.1
Trunk fat-free mass 0.3 1.9 6.1 0.2 2.5 -0.6 0.0 1.5 1.6 2.1 1.3 -0.3
Hip circumference 0.6 2.4 9.7 0.6 3.1 0.3 0.0 1.7 1.9 1.8 1.3 0.5
Time employed in main current job 0.6 0.7 2.3 0.5 -0.2 0.4 0.0 1.2 1.5 1.5 -0.2 0.4
Alcohol intake versus 10 years previously 0.3 0.4 2.0 1.4 -0.2 -0.2 0.0 0.9 0.7 -0.0 -0.5 0.4
Father’s age at death 0.6 0.8 2.0 -0.9 -0.3 1.1 0.0 -0.7 -1.2 -0.6 -1.4 0.9
Worrier / anxious feelings 1.7 3.3 8.4 -2.5 -1.9 -0.1 0.0 -2.7 -2.9 -1.6 -0.0 1.2
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.4 2.4 -0.3 -0.7 -0.2 0.0 -0.5 -0.1 -0.4 -1.5 0.4
Falls in the last year 0.4 0.6 2.9 0.5 -1.7 -0.9 0.0 0.4 0.5 0.8 0.1 0.7
Hair/balding pattern: Pattern 3 0.2 0.3 1.1 -0.5 -0.4 0.3 0.0 -0.2 0.2 -1.0 -0.4 0.6
Number of live births 0.1 0.1 0.5 0.1 0.3 -0.0 0.0 0.2 0.1 0.7 0.3 0.2
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 1.5 -0.4 0.6 1.1 0.0 -1.1 -1.2 -0.8 -0.8 0.5
Pulse rate 0.7 1.2 4.3 0.3 -1.7 0.2 0.0 0.8 1.1 0.8 -0.9 -2.1
Happiness 0.5 0.6 2.3 0.6 0.9 0.9 0.0 -0.7 -1.5 -0.9 -0.0 0.5
Noisy workplace 0.7 0.8 1.8 0.2 0.8 -1.1 0.0 -0.6 -1.3 -1.4 0.8 0.9
Qualifications: A levels/AS levels or equivalent 0.3 0.7 2.4 1.5 -0.7 -0.2 0.0 0.3 -0.7 -1.1 -1.3 -0.1
Serious illness, injury or assault of a close relative in last 2 years 1.1 1.3 7.2 0.2 -2.7 -1.0 0.0 -0.4 -0.7 -0.3 0.4 1.6
Mouth/teeth dental problems: Dentures 0.1 0.2 0.8 0.2 -0.7 0.2 0.0 0.3 0.4 -0.3 -0.4 0.9
Asthma 0.2 0.4 1.8 0.3 -0.5 -1.0 0.0 0.8 0.3 1.3 0.4 -0.1
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 2.5 -0.4 0.6 -0.5 0.0 -0.7 -0.8 0.5 -0.5 -1.6
Medication: Cholesterol lowering 0.5 0.8 2.8 -0.1 -0.3 1.3 0.0 0.3 0.9 1.0 1.7 -0.6
Depression (self-reported) 0.5 0.7 1.3 -1.1 0.0 0.5 0.0 -1.1 -1.0 -0.9 -0.5 -1.0
Medication: Lansoprazole 0.7 0.8 4.1 -0.9 2.0 0.8 0.0 0.4 0.3 0.5 0.7 -0.7
Prospective memory result 0.6 0.7 1.7 1.2 1.3 1.2 0.0 0.8 0.4 0.2 1.0 -0.4
Lung cancer (father) 0.5 0.5 3.4 1.8 -0.1 0.9 0.0 0.6 0.4 -0.0 0.2 0.1
Illnesses of mother 0.5 0.6 2.1 0.6 -0.9 1.5 0.0 -0.3 -0.3 -0.3 -1.1 1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.7 1.4 -0.1 1.0 1.2 0.0 -0.8 -0.8 -0.9 -0.5 1.1
Pulse wave Arterial Stiffness index 0.1 0.1 0.5 -0.2 -0.1 -0.0 0.0 -0.1 -0.1 -0.7 0.1 0.1
Impedance of arm (left) 0.1 0.6 3.7 -0.6 -0.7 1.9 0.0 -0.3 -0.1 -0.0 -0.7 0.0
Arm fat mass (right) 0.7 2.8 7.7 0.5 2.6 0.2 0.0 2.1 2.8 2.5 0.4 -0.2
Trunk predicted mass 0.3 2.0 6.1 0.2 2.5 -0.6 0.0 1.5 1.6 2.1 1.4 -0.3
Standing height 0.2 1.6 6.4 0.1 2.5 0.2 0.0 1.2 0.8 2.2 0.7 -0.6
Length of working week for main job 0.9 1.0 3.8 -0.2 0.3 -0.5 0.0 1.6 1.9 1.4 0.3 -0.5
Exposure to tobacco smoke at home 0.5 0.6 1.7 0.9 -0.0 -0.2 0.0 1.3 1.0 0.6 -1.1 -0.5
Breastfed as a baby 0.9 1.1 2.6 -1.5 0.0 0.4 0.0 -1.4 -1.4 -0.7 -0.2 -1.6
Tense / ‘highly strung’ 0.9 1.5 5.4 -0.2 -1.0 -0.0 0.0 -1.6 -2.0 -2.3 -0.8 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.7 2.0 -0.9 -1.4 1.0 0.0 -0.7 -0.6 -1.2 -0.4 -0.2
Hair/balding pattern: Pattern 4 0.3 0.7 2.7 -1.0 -0.7 -0.1 0.0 -0.5 -0.5 1.3 -0.2 -1.7
Birth weight of first child 0.8 1.4 5.6 -0.3 0.1 2.1 0.0 -0.8 -0.7 0.7 2.4 -0.9
Peak expiratory flow (PEF) 0.7 1.6 4.0 -1.7 -0.3 -0.2 0.0 -2.0 -1.9 -1.5 -1.2 0.5
Pulse wave reflection index 0.1 0.2 1.0 -0.1 1.0 -0.3 0.0 -0.1 -0.3 -0.2 0.1 0.6
Ever highly irritable/argumentative for 2 days 0.9 1.0 3.2 -1.8 -0.7 0.4 0.0 -1.0 -0.9 -1.4 -0.7 -1.2
Loud music exposure frequency 0.3 0.3 0.9 -0.9 0.4 1.0 0.0 -0.5 -0.5 -0.4 0.2 -0.0
Qualifications: O levels/GCSEs or equivalent 0.2 0.4 1.4 0.1 -0.1 0.1 0.0 -0.8 -1.2 -1.0 0.4 0.3
Mouth/teeth dental problems: Bleeding gums 0.9 1.1 3.3 -1.0 -0.7 -1.5 0.0 -1.8 -1.5 -0.8 -0.5 -0.1
Blood clot in the leg (DVT) 0.7 0.9 2.6 1.6 0.2 0.4 0.0 1.5 0.8 1.4 0.2 0.6
Medication: Paracetamol 0.2 0.2 0.5 -0.4 0.6 0.3 0.0 -0.7 -0.7 -0.4 0.3 -0.6
Headache pain in last month 0.6 1.1 4.8 -0.5 -0.3 0.7 0.0 -1.0 -1.0 -1.0 -2.2 -1.0
Medication for cholesterol, blood pressure or diabetes 0.5 0.9 2.5 1.2 0.9 -1.1 0.0 0.1 -0.5 -0.6 -1.2 1.6
Glaucoma (self-reported) 0.3 0.4 1.5 0.4 -0.1 -0.4 0.0 -0.3 -0.4 -1.1 -1.2 0.3
Gout (self-reported) 0.1 0.2 0.6 -0.7 -0.1 0.7 0.0 -0.0 0.2 0.5 0.6 -0.3
Hypothyroidism/myxoedema (self-reported) 0.1 0.1 0.4 0.3 -0.6 -0.1 0.0 -0.5 -0.4 -0.4 -0.4 -0.1
Medication: Amlodipine 0.3 0.5 1.3 -0.3 -0.9 0.7 0.0 -0.2 -0.1 -1.0 -0.7 -1.1
Medication: Ventolin 100micrograms inhaler 0.2 0.3 0.6 0.1 -0.5 0.5 0.0 -0.6 -0.8 -0.5 0.7 0.3
Birth weight 0.3 0.6 1.8 -0.7 1.1 0.5 0.0 -0.7 -0.2 -0.0 1.2 1.3
Chronic bronchitis/emphysema (mother) 0.8 0.9 2.4 1.4 0.5 -1.0 0.0 1.0 0.7 0.0 1.5 1.1
High blood pressure (siblings) 0.6 0.8 2.8 -1.0 -0.1 -0.0 0.0 0.9 1.5 1.7 -0.2 -0.6
Forced vital capacity (FVC), Best measure 0.2 0.5 2.4 0.3 0.6 1.6 0.0 -0.5 -0.7 -0.8 -0.8 0.1
Body fat percentage 0.7 2.6 7.8 0.5 2.6 0.5 0.0 2.2 2.8 1.9 -0.0 -0.1
Leg fat percentage (right) 0.4 1.4 4.4 0.6 1.8 -0.4 0.0 1.7 2.1 1.1 0.7 0.1
Arm fat-free mass (right) 0.5 2.5 7.2 0.4 2.7 -1.0 0.0 1.9 1.9 2.3 1.1 -0.5
Exposure to tobacco smoke outside home 0.7 0.9 5.4 0.3 0.4 0.0 0.0 -1.1 -1.2 -0.1 2.3 0.1
Comparative body size at age 10 0.1 0.4 1.2 -0.1 1.1 0.3 0.0 0.2 0.5 -0.0 1.0 0.8
Number of full brothers 1.1 1.3 5.1 0.5 -0.7 1.6 0.0 1.2 1.1 2.3 0.9 0.5
Worry too long after embarrassment 0.5 0.9 1.8 -1.2 -0.9 -1.0 0.0 -1.1 -1.3 -0.5 -1.3 -0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.7 1.4 -1.2 -0.0 -1.1 0.0 -0.9 -1.2 -0.8 -0.7 0.1
Wheeze or whistling in the chest in last year 0.6 1.1 3.5 0.2 -0.1 1.0 0.0 1.5 1.6 1.9 0.9 -0.4
Number of children fathered 0.6 0.7 2.8 -0.8 1.0 0.8 0.0 -0.9 0.0 -0.2 1.7 -0.0
Reason for reducing amount of alcohol drunk: Health precaution 0.1 0.1 0.4 0.0 -0.1 -0.2 0.0 0.1 0.1 0.2 -0.4 -0.6
Age at first live birth 0.5 0.9 4.8 1.1 -0.2 -2.2 0.0 0.7 0.7 0.5 0.0 0.7
Pulse wave peak to peak time 0.1 0.1 0.7 0.1 0.4 -0.0 0.0 0.3 0.2 0.8 -0.1 -0.1
Health satisfaction 0.7 0.9 4.3 -0.8 -2.1 0.4 0.0 -0.6 -0.7 -1.1 -0.7 -0.8
Shortness of breath walking on level ground 0.3 0.4 1.6 -1.3 0.2 -1.1 0.0 -0.3 -0.1 0.2 0.2 -0.4
Qualifications: College or University degree 0.1 0.4 1.1 -0.1 -0.8 1.0 0.0 -0.1 -0.1 -0.3 -0.8 -1.1
Eye problems/disorders: None of the above 0.6 0.6 1.9 -0.8 -1.4 -1.0 0.0 -0.8 -0.4 0.5 1.0 0.1
Mouth/teeth dental problems: Loose teeth 1.1 1.4 7.4 -0.7 1.3 0.1 0.0 -0.6 -0.8 -0.4 -2.7 -1.2
Emphysema/chronic bronchitis 0.1 0.2 0.8 -0.2 -0.1 -0.9 0.0 0.1 -0.2 0.5 0.2 -0.5
Medication for pain relief, constipation, heartburn 0.3 0.4 1.5 0.5 -0.5 -0.8 0.0 0.0 -0.0 -0.6 -1.0 1.2
Neck or shoulder pain in last month 0.5 0.7 3.8 0.4 0.4 1.1 0.0 0.1 -0.1 -0.8 -1.9 0.6
Medication: Blood pressure 0.4 0.7 2.4 -1.2 -0.8 0.1 0.0 0.0 0.7 0.1 1.2 -1.6
Angina (self-reported) 0.4 0.6 1.8 0.1 -0.0 0.8 0.0 0.9 1.4 1.3 0.3 0.2
Migraine (self-reported) 0.3 0.4 2.3 1.1 -0.4 1.5 0.0 0.2 -0.1 -0.0 -0.0 0.3
Medication: Ibuprofen 0.3 0.4 1.1 -0.2 0.7 -0.3 0.0 -0.2 -0.1 0.7 -1.0 -1.0
Medication: Allopurinol 0.2 0.2 0.7 -0.7 -0.8 0.1 0.0 -0.2 -0.0 0.1 0.8 0.2
Medication: Omeprazole 1.0 1.2 3.6 0.1 0.2 1.9 0.0 -1.1 -1.3 -1.3 1.5 -0.2
Medication: Seretide 50 evohaler 0.8 1.0 2.5 1.6 -0.8 1.0 0.0 1.3 1.0 1.2 -0.4 -0.3
Mean time to correctly identify matches 0.3 0.5 2.0 0.6 -0.5 0.9 0.0 0.6 0.1 0.1 1.4 0.9
Heart disease (mother) 1.5 1.9 9.7 -3.1 0.0 -0.0 0.0 -1.6 -1.2 -0.8 -0.1 -1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 0.4 0.4 -0.6 -0.6 0.0 -0.0 0.1 -0.4 0.4 0.2
Whole body fat mass 0.7 2.9 8.1 0.7 2.7 0.4 0.0 2.3 2.9 2.2 0.4 -0.4
Leg fat mass (right) 0.7 2.7 7.6 1.0 2.2 -0.2 0.0 2.3 2.8 2.1 1.0 -0.1
Arm predicted mass (right) 0.4 2.2 6.8 0.5 2.6 -0.9 0.0 1.8 1.7 2.1 1.1 -0.5
Pulse rate, automated reading 0.1 0.5 1.7 -0.1 -0.4 0.1 0.0 -1.0 -0.5 -1.3 -0.9 -0.5
Alcohol intake frequency. 0.1 0.3 1.3 1.0 -0.1 0.6 0.0 0.1 0.3 -1.1 -0.2 0.1
Comparative height size at age 10 0.1 0.7 1.7 0.2 1.0 1.3 0.0 0.7 0.9 1.1 1.2 -0.1
Number of full sisters 0.2 0.3 1.8 0.3 -1.3 -0.3 0.0 0.3 0.3 0.3 -0.3 -0.6
Suffer from ‘nerves’ 0.1 0.2 0.6 0.6 0.0 -0.6 0.0 0.2 -0.5 0.4 -0.3 0.8
Overall health rating 0.5 1.0 2.5 0.9 -1.6 1.0 0.0 1.1 1.1 0.8 -1.1 -0.6
Chest pain or discomfort 0.3 0.4 1.9 0.2 0.1 1.1 0.0 0.6 0.5 1.4 0.0 -0.5
Had major operations 2.6 3.1 11.2 -3.3 0.4 -2.0 0.0 -2.0 -1.5 -1.6 0.1 -1.8
Age at last live birth 1.0 1.4 7.1 1.4 -0.6 -2.7 0.0 0.5 0.5 0.8 0.3 1.5
Family relationship satisfaction 0.4 0.5 2.1 -0.6 1.2 1.4 0.0 0.1 -0.3 0.0 0.8 0.2
Leg pain on walking 1.1 1.4 3.8 -1.6 -0.9 -1.9 0.0 -1.3 -1.1 -1.1 -0.9 -0.4
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.0 0.6 -0.0 -0.2 0.0 0.9 0.8 1.0 0.6 -0.4
Commuting to job workplace: Car/motor vehicle 0.9 1.0 2.5 0.1 1.0 0.5 0.0 -1.5 -1.6 -1.3 1.0 -0.7
Illness, injury, bereavement, stress in last 2 years 1.4 1.8 3.9 -1.8 0.5 1.1 0.0 -2.0 -1.5 -1.6 0.7 -1.3
Medication: Aspirin 0.2 0.2 0.9 -0.3 0.1 0.1 0.0 0.2 0.6 0.3 0.9 -0.9
Supplements: Vitamin C 0.6 0.8 3.6 1.9 0.8 0.9 0.0 0.5 0.6 0.2 0.6 0.9
Knee pain experienced in last month 0.1 0.2 0.5 0.6 -0.2 0.5 0.0 -0.2 -0.2 -0.7 -0.3 -0.1
Hypertension (Self-reported) 0.8 2.3 5.7 -2.4 -1.4 -2.0 0.0 -1.7 -0.9 -0.7 1.0 -2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 3.7 1.9 0.3 1.0 0.0 0.6 -0.2 -1.0 0.4 1.3
Illnesses of father: Heart disease 0.6 0.8 2.1 -0.2 1.1 -0.3 0.0 0.9 1.1 1.5 1.3 0.1
Illnesses of siblings: Diabetes 0.4 0.6 1.5 -1.2 1.1 -1.0 0.0 0.0 0.2 0.3 -0.2 -1.0
Smoking status: Previous 0.5 0.7 3.6 -0.0 -0.7 -0.4 0.0 -0.9 -1.0 -0.4 1.9 -0.0
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 1.7 -0.6 0.3 -0.7 0.0 -1.2 -1.3 -0.3 -1.0 -0.4
Whole body fat-free mass 0.5 2.7 7.8 0.3 2.8 0.1 0.0 1.9 2.1 2.5 1.4 -0.3
Leg fat-free mass (right) 0.7 3.8 9.7 0.5 2.9 1.3 0.0 2.3 2.7 3.1 1.1 -0.1
Arm fat percentage (left) 0.8 3.3 11.4 0.5 2.1 0.7 0.0 2.5 3.4 2.6 0.1 -0.2
Average weekly red wine intake 0.4 0.5 2.3 0.5 0.5 -0.3 0.0 0.9 0.8 0.5 -1.5 -0.2
Handedness (chirality/laterality): Left-handed 1.1 1.3 7.1 1.2 0.2 0.5 0.0 1.2 1.1 0.4 -2.7 0.5
Mood swings 0.6 1.1 3.2 -1.5 0.5 1.8 0.0 -1.1 -1.1 -0.6 -1.2 -0.2
Loneliness, isolation 0.5 0.6 2.2 -0.3 -0.8 1.2 0.0 -0.1 -0.5 0.4 0.9 -1.5
Long-standing illness, disability or infirmity 1.1 1.6 5.8 0.7 -2.4 0.8 0.0 0.9 1.2 1.0 -0.9 -1.9
Ever had bowel cancer screening 1.5 1.8 5.9 -1.2 -0.5 0.6 0.0 -1.8 -1.5 -2.4 -1.3 0.8
Diabetes diagnosed by doctor 0.3 0.5 1.1 -0.7 -0.9 1.1 0.0 -0.5 0.0 -0.0 -1.1 -0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 2.8 0.6 -1.7 -0.3 0.0 0.2 0.1 0.3 0.8 -0.6
Friendships satisfaction 1.0 1.2 3.3 -1.2 -0.8 0.9 0.0 -1.6 -1.8 -1.4 -0.1 -0.6
Qualifications: nursing, teaching 0.9 1.4 3.8 -0.2 0.8 0.5 0.0 -1.3 -1.7 -1.8 -1.9 -0.8
Commuting to job workplace: Walk 1.8 2.0 4.4 -1.8 1.0 0.5 0.0 -1.7 -2.1 -2.1 -1.2 -0.6
Eye problems/disorders: Cataract 0.3 0.4 1.0 1.0 0.3 0.2 0.0 1.0 0.6 -0.3 -0.9 0.4
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 3.7 0.7 1.9 1.1 0.0 0.0 0.3 -0.5 -0.3 1.1
Medication for cholesterol 0.7 1.0 2.9 0.6 -0.1 1.4 0.0 1.7 1.4 1.4 -0.4 0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.2 1.4 4.9 -0.5 2.2 1.4 0.0 0.3 0.3 0.5 -0.3 2.1
Back pain experienced in last month 0.3 0.5 1.7 -0.5 0.2 -0.1 0.0 -1.0 -1.0 -0.1 -1.3 -0.5
Mineral and other dietary supplements 1.5 2.0 9.2 0.6 -3.0 0.4 0.0 1.6 1.6 1.8 0.1 0.5
Breast cancer (self-reported) 0.8 0.9 4.8 -0.1 1.0 2.2 0.0 1.1 0.7 0.9 0.2 -0.0
Asthma (self-reported) 0.2 0.4 1.5 0.5 -0.4 -0.8 0.0 0.9 0.3 1.2 -0.0 -0.2
Osteoporosis (self-reported) 1.1 1.3 5.7 -0.0 -2.4 0.4 0.0 -0.5 -0.1 -0.3 0.0 -2.3
Osteoarthritis (self-reported) 0.3 0.4 3.2 0.2 1.8 0.2 0.0 0.1 0.3 0.5 0.6 -0.2
Medication: Aspirin 0.3 0.4 0.9 0.1 0.3 -0.1 0.0 0.7 1.0 0.7 0.8 -0.9
Medication: Gliclazide 0.5 0.6 1.5 0.9 -0.9 0.8 0.0 0.7 0.3 0.1 -1.1 1.2
Illnesses of father: None of the above (group 1) 0.5 0.7 2.3 1.5 1.2 -0.1 0.0 0.3 0.2 -0.4 -1.4 0.4
Smoking status: Current 1.0 1.6 4.3 1.1 -1.1 2.1 0.0 1.8 1.8 1.1 -0.4 0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 1.0 -0.4 1.0 0.2 0.0 -0.8 -0.3 -0.4 -0.8 1.0
Whole body water mass 0.5 2.7 7.7 0.3 2.8 0.1 0.0 1.9 2.1 2.6 1.4 -0.3
Leg predicted mass (right) 0.8 4.0 10.0 0.5 2.9 1.4 0.0 2.4 2.9 3.2 1.2 -0.1
Arm fat mass (left) 0.7 3.1 8.6 0.4 2.5 0.4 0.0 2.3 2.9 2.6 0.5 -0.2
Number of self-reported non-cancer illnesses 0.2 0.3 0.7 -0.1 -0.7 -0.0 0.0 -0.8 -0.6 -0.3 -0.4 -0.7
Average weekly champagne plus white wine intake 0.3 0.4 1.3 -0.6 0.6 -0.8 0.0 -0.8 -0.5 -1.1 -0.8 0.0
Miserableness 0.6 1.0 4.7 -1.4 -0.4 0.8 0.0 -0.7 -0.4 -0.3 -2.2 -0.9
Guilty feelings 0.6 0.9 4.2 0.3 -0.1 -1.2 0.0 0.6 0.4 1.1 2.1 0.6
Wears glasses or contact lenses 0.1 0.1 0.8 -0.4 0.1 -0.0 0.0 -0.5 -0.2 -0.1 -0.9 -0.1
Ever taken oral contraceptive pill 0.2 0.3 0.9 -0.5 -0.1 -1.0 0.0 0.1 -0.1 0.8 -0.3 -0.7
Hearing aid user 1.4 1.6 5.6 2.0 0.0 0.5 0.0 2.4 2.0 0.5 -0.1 0.5
Mother’s age at death 1.2 1.5 6.0 1.1 2.4 0.7 0.0 0.8 -0.1 -0.4 -0.3 2.3
Financial situation satisfaction 0.3 0.4 1.2 0.6 -0.5 0.2 0.0 1.1 0.6 1.0 0.1 -0.8
Tinnitus: Yes, now most or all of the time 0.3 0.3 0.8 -0.6 -0.0 -0.6 0.0 -0.7 -0.6 -0.9 0.3 0.8
Commuting to job workplace: Public transport 0.2 0.3 1.0 -0.1 -0.2 1.0 0.0 0.3 0.6 0.8 0.4 0.2
Eye problems/disorders: Glaucoma 0.7 0.8 1.9 -0.9 0.5 -0.8 0.0 -1.4 -1.4 -1.4 -0.5 -0.3
Medication: Blood pressure 0.3 0.7 2.1 -0.5 -1.0 -1.5 0.0 -0.8 -0.6 -1.2 -0.4 -0.3
Pain type(s) experienced in last month: Hip pain 0.7 0.9 2.2 -1.3 -0.7 -0.0 0.0 -1.5 -0.9 -1.3 -0.2 -0.9
Supplements: Fish oil (including cod liver oil) 0.7 0.9 3.4 -0.5 1.9 -0.6 0.0 -1.1 -1.1 -1.3 0.2 -0.2
High cholesterol (Self-reported) 0.8 1.3 5.5 -2.1 -0.1 0.1 0.0 -1.0 -0.2 0.0 1.0 -2.3
Medication: Bendroflumethiazide 0.9 1.3 3.8 -1.5 1.2 0.2 0.0 -1.5 -0.8 -1.3 0.1 -1.9
Medication: Paracetamol 0.3 0.5 1.1 -0.9 0.3 0.5 0.0 -1.1 -0.9 -0.8 -0.2 -0.5
Medication: Lisinopril 1.1 1.4 2.9 -0.8 -1.5 1.5 0.0 -0.3 -0.3 -1.1 -1.7 -1.6
Medication: Atorvastatin 0.6 0.8 5.4 0.0 1.1 2.3 0.0 -0.1 0.2 -0.5 -0.5 -0.0
Illnesses of father: High blood pressure 0.5 0.6 2.1 -1.4 -0.8 -0.4 0.0 0.3 0.4 0.9 1.2 -0.4
Alcohol drinker status: Never 0.1 0.1 0.4 0.5 0.7 -0.1 0.0 -0.2 -0.3 -0.2 -0.2 0.2
Ever smoked 0.2 0.4 1.6 0.1 -1.3 -0.1 0.0 -0.0 -0.3 0.1 1.2 -0.1
Basal metabolic rate 0.6 3.1 8.5 0.4 2.9 0.2 0.0 2.1 2.4 2.8 1.3 -0.2
Leg fat percentage (left) 0.4 1.5 4.8 0.5 2.0 -0.2 0.0 1.8 2.2 1.0 0.0 0.3
Arm fat-free mass (left) 0.5 2.6 8.2 0.5 2.9 -0.7 0.0 2.0 1.9 2.4 1.1 -0.2
Number of operations (self-reported) 1.1 1.6 7.0 -2.6 2.2 -1.2 0.0 -0.7 -0.0 1.0 -0.1 -0.3
Average weekly beer plus cider intake 0.1 0.2 0.7 0.8 -0.2 0.1 0.0 0.6 0.3 0.4 0.5 0.3
Irritability 0.7 1.1 3.3 -1.4 0.1 -0.3 0.0 -1.5 -1.8 -1.3 -0.8 -0.5
Risk taking 0.6 0.9 3.0 1.3 1.7 0.3 0.0 0.5 0.3 -0.2 0.3 1.6
Ever had prostate specific antigen (PSA) test 0.3 0.3 1.0 -0.2 -0.4 -0.5 0.0 -0.6 -0.8 -1.0 0.2 0.5
Fractured/broken bones in last 5 years 2.0 2.6 4.9 2.1 -1.4 -2.0 0.0 1.7 1.4 2.2 1.2 1.4
Age started oral contraceptive pill 0.3 0.4 1.5 -0.1 1.2 -1.2 0.0 0.1 0.1 0.5 -0.0 -0.2
Diastolic blood pressure, automated reading 0.3 1.0 3.3 -1.8 -0.5 -0.7 0.0 -1.5 -0.8 -0.9 -0.9 -0.6
Ever depressed for a whole week 0.5 0.7 2.1 -1.4 -0.4 1.0 0.0 -0.7 -1.2 -0.7 -0.1 -0.6
Unable to work because of sickness or disability 0.8 1.1 2.4 1.5 0.5 0.5 0.0 1.5 1.5 0.9 -0.2 -1.2
Commuting to job workplace: Cycle 0.2 0.2 1.4 0.2 0.5 -1.2 0.0 -0.3 -0.4 -0.2 0.1 0.5
Myopia 0.5 0.7 6.3 0.1 -2.5 -0.4 0.0 -0.2 0.0 0.2 0.0 -0.2
Vascular/heart problems diagnosed by doctor 0.7 1.8 5.0 2.2 1.0 2.2 0.0 1.4 0.6 0.8 -0.4 1.6
Cholesterol lowering medication 0.6 0.8 1.9 -1.1 -0.8 -0.3 0.0 -1.2 -1.2 -1.4 0.9 -0.3
Medication: Omeprazole (e.g. Zanprol) 1.9 2.3 5.5 -0.6 -0.2 1.5 0.0 -2.1 -2.4 -2.1 1.7 -0.6
Pain experienced in last month 1.4 2.3 5.2 2.1 0.1 -2.3 0.0 1.9 1.7 1.7 0.9 1.0
Supplements: Calcium 0.6 0.6 1.6 1.1 1.3 1.0 0.0 0.1 -0.1 -0.5 1.2 0.2
Basal cell carcinoma (self-reported) 0.4 0.5 1.8 -0.4 0.8 1.1 0.0 -0.5 -0.5 -0.3 1.3 0.6
Heart attack/myocardial infarction (self-reported) 0.3 0.4 2.8 0.2 -0.0 -1.7 0.0 -0.1 0.3 -0.7 -0.2 -0.1
Deep venous thrombosis (DVT) (self-reported) 0.8 1.1 3.2 1.8 -0.0 0.6 0.0 1.6 1.0 1.4 -0.3 0.6
Heart disease (siblings) 1.5 1.9 8.7 -1.4 -0.1 -0.8 0.0 -0.0 0.7 1.7 2.9 -1.4
Alcohol drinker status: Previous 0.6 0.7 1.8 -0.1 -0.8 0.5 0.0 -0.7 -1.0 -1.3 -0.5 -1.3
Pack years of smoking 0.8 1.1 5.7 -1.2 -0.0 0.0 0.0 -0.7 -0.5 -2.4 -0.7 -1.3
Impedance of whole body 0.1 0.8 1.7 -0.4 -1.3 0.5 0.0 -0.9 -1.2 -1.1 -1.1 -0.1
Leg fat mass (left) 0.7 2.7 7.9 0.9 2.4 0.1 0.0 2.4 2.8 2.0 0.7 -0.1
Arm predicted mass (left) 0.4 2.2 8.8 0.4 3.0 -0.6 0.0 1.7 1.7 2.1 0.9 -0.2