[Hub]/) : Traits : Blood Eosinophil Count :

chr3:195,734,915-197,161,849

Best TWAS P=1.46e-15 · Best GWAS P=4.06e-21 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CEP19 0.18 0.10 lasso 6 0.12 1.3e-14 -5.6 6.5 1.0e-10 -0.05 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum PIGX 0.25 0.08 lasso 4 0.08 7.5e-05 -5.2 5.8 8.9e-09 -0.09 0.84 0.01 TRUE
3 GTEx Adipose Visceral Omentum CEP19 0.27 0.15 lasso 4 0.15 5.3e-08 -5.6 5.7 1.1e-08 -0.08 1.00 0.00 FALSE
4 GTEx Adrenal Gland PIGX 0.24 0.01 lasso 6 0.04 1.1e-02 -5.0 6.0 2.3e-09 -0.07 0.44 0.09 TRUE
5 GTEx Adrenal Gland CEP19 0.24 0.17 lasso 3 0.15 4.8e-06 -5.6 5.7 1.5e-08 -0.08 0.69 0.07 FALSE
6 GTEx Artery Coronary CEP19 0.33 0.15 lasso 3 0.14 2.0e-05 -5.2 5.3 1.3e-07 -0.08 0.53 0.02 FALSE
7 GTEx Artery Tibial CEP19 0.11 0.07 lasso 3 0.07 5.3e-06 -5.6 5.6 1.7e-08 -0.08 0.89 0.00 FALSE
8 GTEx Brain Caudate basal ganglia CEP19 0.31 0.18 lasso 5 0.18 8.0e-06 -5.5 5.9 4.9e-09 -0.08 0.58 0.05 FALSE
9 GTEx Cells EBV-transformed lymphocytes CEP19 0.30 0.12 lasso 4 0.13 4.2e-05 -5.0 5.1 3.1e-07 -0.09 0.58 0.02 FALSE
10 GTEx Esophagus Muscularis PIGX 0.12 0.01 lasso 5 0.02 3.7e-02 -5.1 5.3 1.4e-07 -0.11 0.31 0.03 TRUE
11 GTEx Esophagus Muscularis CEP19 0.16 0.11 lasso 4 0.07 3.4e-05 -5.5 5.5 3.8e-08 -0.07 0.97 0.00 FALSE
12 GTEx Heart Atrial Appendage CEP19 0.19 0.08 lasso 6 0.07 5.9e-04 -5.9 5.6 2.0e-08 -0.11 0.68 0.05 FALSE
13 GTEx Lung PIGX 0.21 0.08 enet 7 0.08 1.8e-06 -5.5 5.6 2.3e-08 -0.09 0.98 0.00 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic PIGX 0.17 0.11 lasso 3 0.13 1.7e-07 -5.1 5.5 3.0e-08 -0.11 0.99 0.00 FALSE
15 GTEx Skin Sun Exposed Lower leg NRROS 0.07 0.02 enet 14 0.03 9.6e-04 -5.5 -8.0 1.5e-15 0.53 0.02 0.86 TRUE
16 GTEx Spleen CEP19 0.51 0.20 lasso 6 0.17 3.2e-05 -5.2 5.1 2.8e-07 -0.11 0.59 0.07 FALSE
17 GTEx Stomach PIGX 0.22 0.18 lasso 2 0.16 3.7e-08 -5.2 5.2 1.8e-07 -0.07 0.98 0.00 FALSE
18 GTEx Testis CEP19 0.58 0.50 lasso 2 0.50 5.6e-25 -5.9 5.8 6.5e-09 -0.08 1.00 0.00 TRUE
19 GTEx Thyroid PIGX 0.12 0.05 lasso 3 0.04 2.3e-04 -5.5 5.2 1.6e-07 -0.09 0.85 0.01 FALSE
20 GTEx Thyroid CEP19 0.24 0.15 enet 24 0.19 1.4e-14 -5.5 5.5 3.3e-08 -0.07 1.00 0.00 TRUE
21 GTEx Whole Blood CEP19 0.10 0.09 lasso 3 0.09 8.0e-09 -5.9 5.3 1.0e-07 -0.09 1.00 0.00 FALSE
22 YFS Blood PIGX 0.07 0.04 bslmm 441 0.04 4.0e-14 -5.0 6.3 3.3e-10 -0.09 1.00 0.00 TRUE
23 The Cancer Genome Atlas Breast Invasive Carcinoma C3orf34 0.03 0.00 blup 60 0.02 6.8e-06 -5.6 6.8 1.0e-11 -0.07 0.02 0.95 TRUE
24 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C3orf34 0.08 0.14 lasso 5 0.15 2.3e-16 -5.2 5.3 1.2e-07 -0.08 0.05 0.95 FALSE
25 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf34 0.05 0.07 lasso 1 0.06 1.1e-07 -5.9 5.9 3.7e-09 -0.09 0.00 1.00 FALSE
26 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C3orf34 0.06 0.05 lasso 2 0.02 2.8e-02 -5.6 5.6 2.3e-08 -0.08 0.02 0.88 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma C3orf34 0.07 0.09 lasso 2 0.09 1.2e-10 -5.1 5.4 7.0e-08 -0.11 0.05 0.95 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma C3orf34 0.05 0.06 enet 10 0.05 2.8e-06 -5.9 6.7 2.5e-11 -0.05 0.00 0.99 FALSE
29 The Cancer Genome Atlas Prostate Adenocarcinoma PAK2 0.03 0.00 blup 83 0.01 1.4e-02 6.8 -5.4 6.1e-08 0.09 0.05 0.36 TRUE
30 The Cancer Genome Atlas Testicular Germ Cell Tumors C3orf34 0.20 0.21 lasso 5 0.23 1.5e-08 -5.5 5.8 7.2e-09 -0.08 0.02 0.97 FALSE
31 The Cancer Genome Atlas Testicular Germ Cell Tumors PIGX 0.09 0.06 lasso 4 0.05 5.7e-03 4.7 5.7 9.6e-09 -0.09 0.06 0.05 TRUE
32 The Cancer Genome Atlas Thyroid Carcinoma C3orf34 0.11 0.11 blup 59 0.12 1.4e-11 -5.0 5.5 3.4e-08 -0.05 0.05 0.95 FALSE
33 The Cancer Genome Atlas Thyroid Carcinoma LRRC33 0.09 0.03 enet 12 0.06 6.4e-07 4.2 -6.0 2.0e-09 0.10 0.73 0.02 FALSE