[Hub]/) : Traits : Blood Eosinophil Count :

chr5:9,999,146-11,452,037

Best TWAS P=3.33e-14 · Best GWAS P=1.91e-23 conditioned to 8.13e-19

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial DAP 0.31 0.07 enet 28 0.20 2.8e-15 6.1 -5.8 8.0e-09 0.09 1.00 0.00 FALSE
2 GTEx Cells EBV-transformed lymphocytes DAP 0.34 0.14 lasso 8 0.26 6.5e-09 5.8 -6.2 6.4e-10 0.01 0.89 0.01 FALSE
3 GTEx Cells Transformed fibroblasts DAP 0.31 0.19 lasso 5 0.26 1.4e-19 5.4 -5.4 7.4e-08 0.08 1.00 0.00 FALSE
4 GTEx Colon Transverse DAP 0.35 0.16 lasso 6 0.18 4.5e-09 6.1 -5.8 6.5e-09 0.01 0.85 0.01 FALSE
5 GTEx Esophagus Muscularis DAP 0.27 0.15 lasso 8 0.24 5.6e-15 6.1 -5.4 5.9e-08 0.04 1.00 0.00 FALSE
6 GTEx Heart Atrial Appendage DAP 0.26 0.08 lasso 4 0.17 4.0e-08 -2.3 -5.3 8.9e-08 0.05 0.51 0.02 FALSE
7 GTEx Skin Sun Exposed Lower leg DAP 0.21 0.11 lasso 5 0.16 3.9e-13 6.1 -5.9 4.1e-09 0.05 1.00 0.00 FALSE
8 GTEx Thyroid DAP 0.24 0.11 lasso 7 0.13 3.3e-10 6.1 -6.0 2.3e-09 0.03 1.00 0.00 FALSE
9 NTR Blood DAP 0.03 0.01 enet 19 0.02 2.2e-06 5.8 -6.9 4.6e-12 -0.07 0.97 0.00 FALSE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma DAP 0.06 0.00 blup 105 0.02 1.3e-02 5.4 -7.6 3.3e-14 -0.16 0.04 0.11 TRUE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DAP 0.07 0.04 blup 105 0.04 3.4e-05 5.8 -5.5 2.8e-08 -0.05 0.54 0.02 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DAP 0.06 0.05 lasso 3 0.04 1.7e-05 6.1 -6.3 3.0e-10 -0.02 0.63 0.01 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma DAP 0.05 0.04 blup 105 0.03 7.9e-05 5.4 6.7 2.9e-11 0.08 0.70 0.01 FALSE
14 The Cancer Genome Atlas Pancreatic Adenocarcinoma DAP 0.07 0.10 lasso 1 0.07 8.0e-04 6.1 -6.1 1.2e-09 0.00 0.14 0.09 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma DAP 0.08 0.07 lasso 4 0.06 2.7e-07 5.4 -5.3 9.0e-08 0.06 0.98 0.00 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma DAP 0.07 0.07 lasso 1 0.06 1.9e-06 5.4 -5.4 8.0e-08 0.06 0.87 0.02 FALSE