[Hub]/) : Traits : Blood Eosinophil Count :

chr5:34,920,257-36,938,041

Best TWAS P=1.02e-53 · Best GWAS P=1.68e-51 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NADKD1 0.08 0.06 bslmm 563 0.05 1.3e-06 -2.3 -7.0 1.7e-12 0.30 0.97 0.00 FALSE
2 GTEx Brain Frontal Cortex BA9 SPEF2 0.39 0.23 enet 27 0.22 1.8e-06 -5.4 -6.3 3.4e-10 0.49 0.81 0.02 FALSE
3 GTEx Brain Nucleus accumbens basal ganglia SPEF2 0.31 0.24 lasso 6 0.19 9.2e-06 -5.4 -5.3 9.8e-08 0.39 0.40 0.17 FALSE
4 GTEx Cells Transformed fibroblasts SPEF2 0.26 0.01 enet 56 0.04 2.6e-04 -1.3 -6.0 1.9e-09 0.34 0.17 0.58 FALSE
5 METSIM Adipose SPEF2 0.06 0.01 blup 522 0.03 4.0e-05 3.1 -6.7 1.5e-11 0.37 0.74 0.02 FALSE
6 YFS Blood IL7R 0.03 0.01 bslmm 467 0.01 8.1e-05 5.9 7.1 1.4e-12 -0.39 0.82 0.05 FALSE
7 YFS Blood SKP2 0.03 0.02 enet 16 0.03 4.9e-10 5.8 6.2 6.6e-10 -0.19 0.97 0.00 TRUE
8 The Cancer Genome Atlas Glioblastoma Multiforme SPEF2 0.16 0.00 blup 136 0.08 1.9e-03 -6.3 -6.5 7.6e-11 0.47 0.09 0.36 FALSE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SPEF2 0.09 0.00 blup 135 0.01 8.1e-02 1.3 5.3 1.2e-07 -0.37 0.11 0.05 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma SPEF2 0.03 0.04 lasso 5 0.02 8.4e-04 -5.4 -5.4 7.5e-08 0.39 0.38 0.09 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IL7R 0.04 0.03 lasso 3 0.02 9.8e-04 -15.0 -15.4 1.0e-53 0.96 0.00 0.99 TRUE