Hub : Genes

DAP

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0660 0.0250 3.1e-03 0.017 0.022 0.010 0.022 0.014 3.2e-03 1.0e-03 1.9e-02 9.8e-04 7.0e-03
2 GTEx Adipose Subcutaneous 0.2490 0.0510 6.1e-07 0.090 NA 0.238 NA 0.235 8.5e-08 NA 2.2e-19 NA 4.0e-19
3 GTEx Adipose Visceral Omentum 0.2060 0.0620 1.2e-03 0.072 NA 0.094 NA 0.093 1.3e-04 NA 1.4e-05 NA 1.6e-05
4 GTEx Artery Aorta 0.2790 0.0600 6.1e-06 0.134 NA 0.191 NA 0.184 8.2e-08 NA 9.6e-11 NA 2.2e-10
5 GTEx Artery Tibial 0.3140 0.0511 5.6e-10 0.068 NA 0.196 NA 0.173 4.9e-06 NA 2.8e-15 NA 1.7e-13
6 GTEx Breast Mammary Tissue (Female) 0.3049 0.1199 2.6e-02 0.022 NA 0.005 NA -0.002 7.1e-02 NA 2.2e-01 NA 3.7e-01
7 GTEx Cells EBV-transformed lymphocytes 0.3390 0.0890 1.1e-03 0.138 NA 0.254 NA 0.256 3.0e-05 NA 7.4e-09 NA 6.5e-09
8 GTEx Cells Transformed fibroblasts 0.3070 0.0610 2.0e-07 0.187 NA 0.249 NA 0.260 5.4e-14 NA 1.1e-18 NA 1.4e-19
9 GTEx Colon Transverse 0.3460 0.0750 2.7e-05 0.164 NA 0.131 NA 0.183 3.2e-08 NA 8.8e-07 NA 4.5e-09
10 GTEx Esophagus Mucosa 0.1610 0.0520 1.1e-03 0.052 NA 0.180 NA 0.175 2.2e-04 NA 3.8e-12 NA 8.1e-12
11 GTEx Esophagus Muscularis 0.2710 0.0620 1.0e-05 0.147 NA 0.243 NA 0.244 3.2e-09 NA 6.7e-15 NA 5.6e-15
12 GTEx Heart Atrial Appendage 0.2640 0.0820 2.2e-03 0.077 NA 0.106 NA 0.171 2.5e-04 NA 1.8e-05 NA 4.0e-08
13 GTEx Lung 0.3190 0.0688 9.8e-07 0.212 NA 0.203 NA 0.256 3.4e-16 NA 1.9e-15 NA 1.2e-19
14 GTEx Nerve Tibial 0.4047 0.0614 5.7e-10 0.108 NA 0.345 NA 0.304 4.6e-08 NA 3.2e-25 NA 6.9e-22
15 GTEx Pancreas 0.3370 0.0780 1.7e-04 0.162 NA 0.236 NA 0.211 2.4e-07 NA 2.4e-10 NA 2.5e-09
16 GTEx Skin Sun Exposed Lower leg 0.2060 0.0540 6.4e-05 0.108 NA 0.137 NA 0.159 3.1e-09 NA 1.8e-11 NA 3.9e-13
17 GTEx Testis 0.2810 0.0700 3.8e-05 -0.001 NA 0.134 NA 0.088 3.4e-01 NA 1.6e-06 NA 1.0e-04
18 GTEx Thyroid 0.2440 0.0530 2.4e-06 0.112 NA 0.119 NA 0.131 7.0e-09 NA 2.1e-09 NA 3.3e-10
19 GTEx Whole Blood 0.2470 0.0470 1.8e-07 0.074 NA 0.142 NA 0.126 2.5e-07 NA 5.0e-13 NA 1.2e-11
20 METSIM Adipose 0.1264 0.0310 1.6e-07 0.031 0.050 0.059 0.061 0.061 1.6e-05 4.4e-08 3.3e-09 1.7e-09 1.7e-09
21 NTR Blood 0.0330 0.0105 9.2e-05 0.008 0.013 0.017 0.009 0.012 7.2e-04 3.8e-05 2.2e-06 4.0e-04 7.2e-05
22 ROSMAP Brain Pre-frontal Cortex 0.1379 0.0316 6.8e-09 0.042 0.086 0.110 0.111 0.102 3.3e-06 3.7e-11 5.5e-14 3.8e-14 4.8e-13
23 YFS Blood 0.3512 0.0366 0.0e+00 0.189 0.204 0.269 0.268 0.270 1.1e-59 7.0e-65 3.7e-88 8.1e-88 1.3e-88
24 TCGA Bladder Urothelial Carcinoma 0.0610 0.0350 9.8e-03 0.000 0.017 0.017 NA -0.001 3.5e-01 1.2e-02 1.3e-02 NA 3.6e-01
25 TCGA Breast Invasive Carcinoma 0.0618 0.0237 1.6e-09 0.041 0.051 0.051 NA 0.051 7.2e-09 1.2e-10 1.2e-10 NA 1.2e-10
26 TCGA Colon Adenocarcinoma 0.0890 0.0450 9.1e-03 0.013 0.046 0.014 NA 0.009 5.7e-02 1.2e-03 5.0e-02 NA 9.5e-02
27 TCGA Esophageal Carcinoma 0.3220 0.1450 3.2e-03 0.120 -0.003 0.014 NA 0.045 1.3e-04 4.3e-01 1.1e-01 NA 1.5e-02
28 TCGA Head and Neck Squamous Cell Carcinoma 0.0721 0.0328 5.7e-05 0.040 0.038 0.031 NA 0.032 2.7e-05 3.4e-05 1.8e-04 NA 1.6e-04
29 TCGA Kidney Renal Clear Cell Carcinoma 0.0598 0.0285 5.4e-04 0.054 0.016 0.015 NA 0.041 1.1e-06 5.7e-03 7.8e-03 NA 1.7e-05
30 TCGA Brain Lower Grade Glioma 0.0509 0.0227 6.4e-05 0.036 0.034 0.022 NA 0.025 5.3e-05 7.9e-05 1.3e-03 NA 6.5e-04
31 TCGA Lung Adenocarcinoma 0.0322 0.0161 2.6e-03 0.015 0.005 0.010 NA 0.015 5.5e-03 8.0e-02 1.9e-02 NA 5.9e-03
32 TCGA Lung Squamous Cell Carcinoma 0.0425 0.0196 2.3e-04 0.020 0.037 0.023 NA 0.021 2.0e-03 4.0e-05 1.1e-03 NA 1.7e-03
33 TCGA Pancreatic Adenocarcinoma 0.0700 0.0360 5.5e-03 0.101 0.044 0.046 NA 0.069 5.0e-05 6.2e-03 5.0e-03 NA 8.0e-04
34 TCGA Prostate Adenocarcinoma 0.0840 0.0342 2.5e-05 0.069 0.053 0.062 NA 0.064 9.6e-08 3.2e-06 4.4e-07 NA 2.7e-07
35 TCGA Thyroid Carcinoma 0.0650 0.0290 1.1e-04 0.067 0.047 0.051 NA 0.059 4.3e-07 2.2e-05 9.9e-06 NA 2.0e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35
Bipolar Disorder (2018) 0.1 0.2 0.7 -0.0 0.5 0.6 0.8 0.8 0.9 0.4 0.4 0.1 0.6 0.5 0.4 0.4 0.2 -0.1 0.4 0.5 0.2 0.2 -0.4 0.4 0.8 0.3 0.4 0.4 0.6 0.7 -0.5 0.2 0.1 -0.1 -0.0 0.3 0.1 0.1
Bipolar Disorder or Schizophrenia 0.1 0.2 2.6 0.3 0.3 0.6 0.0 0.6 0.0 -0.0 0.3 -0.1 0.2 -0.1 -0.1 -0.1 -0.2 0.1 0.1 -0.8 0.1 0.0 -1.0 -0.0 -0.3 0.1 0.2 0.7 -0.1 1.6 -0.9 -0.1 -0.3 0.8 0.5 0.1 0.6 0.6
Depressed Affect (Nagel 2018) 1.4 2.9 12.9 0.0 -1.5 -1.3 -1.5 -1.0 -3.3 -1.0 -2.0 -0.5 -0.2 -0.6 -0.6 0.5 -1.0 -1.9 -1.4 -1.8 -2.1 0.2 0.0 0.2 1.4 -0.5 -3.6 -1.2 -2.1 -2.0 -1.0 -1.0 2.5 -1.8 -1.7 -1.4 -3.3 -3.3
Depression (Nagel 2018) 5.6 8.4 26.5 1.2 -2.5 -2.6 -2.4 -2.3 -3.0 -2.7 -4.0 -2.6 -2.7 -2.7 -3.0 -2.0 -2.2 -2.6 -3.4 -5.1 -3.4 -2.3 -3.0 -1.4 1.4 -2.9 -2.6 -2.5 -1.6 -0.6 -1.5 -2.5 4.0 -3.7 -3.4 -2.8 -4.4 -4.4
Intelligence (Savage-Jansen 2018) 0.2 0.7 3.4 -0.4 0.6 0.7 -0.5 0.1 1.1 0.7 1.2 1.0 0.9 0.8 1.0 0.7 1.4 1.8 1.0 0.1 0.6 0.2 0.4 0.7 -0.5 0.9 0.5 1.0 0.3 0.5 1.3 0.7 -0.7 1.0 0.6 0.6 0.8 0.9
Neuroticism (Nagel 2018) 1.5 3.5 13.9 0.5 -2.1 -1.7 -1.6 -1.6 -3.1 -1.5 -2.5 -0.8 -1.0 -1.3 -1.2 -0.5 -1.9 -1.3 -1.8 -2.4 -2.1 -0.5 -1.0 -0.6 0.5 -1.3 -3.7 -1.6 -2.2 -1.8 -1.0 -0.7 2.7 -2.3 -2.2 -1.1 -3.2 -3.2
Schizophrenia (2018) 0.2 0.3 2.4 0.5 0.1 0.4 -0.4 0.2 -0.6 -0.2 0.2 -0.1 -0.0 -0.3 -0.2 -0.2 -0.3 0.2 -0.0 -1.3 0.0 -0.0 -0.8 -0.3 -0.8 0.1 -0.1 0.6 -0.6 1.5 -0.8 -0.3 -0.5 1.2 0.7 -0.2 0.7 0.7
Schizophrenia vs Biploar Disorder 0.2 0.3 2.2 0.7 -0.2 0.3 -0.8 -0.4 -0.9 -0.2 0.5 0.5 0.1 -0.2 0.4 0.4 -0.1 0.7 0.3 -0.1 -0.3 0.6 0.7 0.3 0.4 0.7 -1.1 0.1 -1.5 0.7 -0.4 0.0 0.0 0.5 0.3 -0.3 -0.1 -0.0
Worry (Nagel 2018) 0.3 0.7 4.1 0.2 -0.7 -0.7 -0.8 -0.5 -1.3 -0.4 -1.1 0.2 -0.5 -0.3 -0.3 -0.2 -0.6 -0.2 -0.4 -1.4 -0.4 0.4 -0.6 0.3 -0.4 -0.6 -1.3 -0.3 -2.0 0.1 0.6 0.7 1.7 -1.1 -1.2 0.5 -1.3 -1.3
Alzheimer’s Disease (in mother) 0.2 0.3 1.2 1.0 -0.1 -0.3 -0.6 -0.5 -1.1 -0.3 -0.4 0.0 0.1 -0.1 -0.3 -0.1 -0.3 0.3 -0.1 -1.0 -0.2 0.1 -0.2 0.3 0.9 -0.3 -0.7 -0.1 -0.7 -0.9 -0.2 0.2 1.0 -0.3 -0.5 0.1 -0.5 -0.6
Alzheimer’s Disease (in father) 0.7 0.8 2.3 0.6 -0.6 -1.4 -0.6 -1.1 -1.5 -0.8 -0.7 -1.1 -1.1 -1.1 -0.8 -0.8 -1.3 -0.7 -0.7 0.2 -0.7 -1.3 -0.7 -1.4 0.1 -0.9 -0.3 0.1 0.4 -0.1 -1.0 -0.6 1.2 -0.9 -1.4 -0.7 -0.5 -0.5
Alzheimer’s Disease (including proxy) 1.0 1.5 3.7 1.4 -0.9 -1.3 -0.8 -1.6 -1.8 -1.3 -1.4 -1.3 -1.2 -1.3 -1.3 -1.0 -1.7 -0.4 -1.1 -0.8 -1.1 -1.5 -1.0 -0.9 0.8 -1.3 -1.2 -0.4 -0.8 -0.8 -1.1 -0.9 1.9 -1.2 -1.6 -0.9 -1.3 -1.4
Crohns Disease (2017) 5.9 12.9 21.3 3.1 -4.1 -2.9 -3.6 -4.1 -2.9 -4.3 -3.7 -4.0 -4.2 -3.9 -3.9 -3.4 -3.9 -2.7 -4.2 -1.8 -3.9 -3.1 -2.8 -4.6 1.4 -3.6 -4.2 -4.2 -3.3 -1.9 -3.5 -4.3 3.4 -3.7 -3.5 -4.1 -3.5 -3.5
Irritable Bowel Disease (IBD) 5.8 13.8 26.0 2.7 -4.0 -2.8 -3.3 -4.1 -2.5 -4.7 -3.4 -4.2 -4.2 -3.8 -3.7 -3.1 -3.7 -3.9 -4.2 -1.2 -4.5 -3.1 -2.7 -5.1 2.1 -3.4 -4.5 -4.5 -2.5 -1.8 -4.8 -5.0 3.4 -4.0 -3.4 -4.7 -3.7 -3.8
Ulcerative Colitis (UC) 3.4 6.4 15.6 1.6 -2.4 -1.4 -2.0 -2.3 -1.1 -3.4 -2.1 -2.9 -2.6 -2.5 -2.4 -2.1 -2.1 -3.8 -2.8 -0.5 -3.3 -1.9 -1.7 -3.5 2.0 -2.2 -3.1 -3.2 -1.4 -0.3 -4.0 -3.6 2.2 -2.9 -1.9 -3.2 -2.4 -2.5
Major Depression (MDD) 3.1 3.7 11.7 2.0 -1.9 -2.1 -1.5 -2.2 -1.3 -2.1 -2.1 -2.1 -1.7 -2.0 -1.8 -1.5 -1.7 -2.0 -2.1 -2.1 -2.2 -1.9 -1.3 -1.9 0.7 -1.7 -2.5 -1.9 -0.1 -3.4 -1.7 -2.1 2.1 -1.7 -1.3 -2.0 -2.1 -2.1
Reaction Time 0.1 0.1 0.9 -0.5 -0.1 -0.2 0.1 -0.5 0.3 -0.1 -0.1 0.3 0.0 -0.0 -0.1 0.1 -0.2 -0.3 -0.2 -0.6 -0.3 -0.9 0.3 -0.3 -0.0 -0.0 0.0 0.2 -0.3 0.9 -0.3 0.1 -0.1 -0.1 -0.6 -0.1 -0.4 -0.4
Verbal and Numeric Reasoning (VNR) 0.4 0.9 4.4 -0.2 0.9 0.5 0.4 0.5 2.1 0.9 0.9 1.1 1.0 1.1 0.9 0.8 1.4 1.0 1.0 0.3 0.8 -0.2 0.2 1.1 -0.5 0.8 1.6 1.2 1.6 0.0 1.1 1.0 -0.6 0.9 0.4 0.9 0.8 0.8
Breast Cancer 0.8 1.8 4.5 -1.3 1.2 1.5 2.1 1.7 0.4 1.5 1.6 1.4 1.0 1.4 1.4 1.0 1.3 1.4 1.7 1.4 1.7 1.1 0.3 1.3 -0.8 1.1 1.2 1.3 1.5 0.1 1.2 1.8 -1.2 1.2 1.1 1.8 1.5 1.5
Ovarian Cancer 0.4 0.5 2.2 0.3 -0.2 -0.3 -0.5 0.2 -1.5 -0.7 -0.8 -1.0 -0.7 -1.0 -1.0 -0.9 0.4 -1.5 -0.7 0.3 -0.3 0.7 -0.7 -0.5 0.0 -1.3 0.1 -0.5 0.5 -0.9 0.1 -0.3 1.0 -1.0 -0.8 -0.2 -0.6 -0.6
Prostate Cancer 0.6 0.9 3.8 -1.2 -1.4 -0.8 -1.0 -1.0 -0.0 -0.2 -1.0 -0.4 -1.3 -0.7 -1.1 -1.3 -1.3 1.8 -0.7 -0.7 -0.0 -0.9 -1.5 -0.1 -2.0 -1.3 -0.2 -0.4 -0.7 0.2 0.8 0.4 -0.4 -0.7 0.5 0.7 -0.4 -0.3
Age at First Birth 0.7 1.0 4.5 -0.2 -1.4 -0.8 -1.4 -0.8 -0.1 -1.1 -0.9 -0.8 -0.5 -1.1 -0.9 -0.7 -1.2 -0.6 -1.0 -1.2 -1.1 -0.9 -0.8 -1.3 -0.8 -0.8 -2.1 -1.0 -0.8 -1.1 -1.0 -1.0 0.2 -0.9 0.0 -0.9 -1.1 -1.0
Bipolar Disorder (2011) 2.1 2.0 4.9 -0.7 1.4 2.2 1.4 2.2 2.0 1.7 1.8 1.5 2.2 1.5 1.9 2.1 1.4 -0.5 1.6 1.2 1.0 1.2 1.6 2.1 -0.2 2.0 0.8 1.6 0.4 1.0 0.3 0.0 -1.2 0.0 1.5 0.8 0.9 0.8
Body Mass Index (BMI) (2010) 0.4 0.5 2.2 0.6 -0.8 -1.5 -0.6 -0.8 -0.6 -0.3 -0.7 -0.4 -1.0 -0.5 -0.9 -1.3 -0.4 -0.2 -0.5 -1.2 0.2 -0.0 -0.5 -0.5 -1.2 -1.3 0.2 -0.6 -0.5 -0.1 0.6 0.6 -0.3 -0.8 -0.0 0.6 0.2 0.2
Coronary Artery Disease (CAD) 0.5 0.7 3.2 0.4 -0.8 -1.0 0.1 -0.5 -0.9 -0.6 -0.9 -1.2 -1.6 -0.9 -1.3 -1.4 -0.9 -0.2 -1.1 -0.4 -0.4 -0.1 -0.7 -0.5 -0.6 -1.4 0.4 -0.5 -0.4 1.8 -0.2 -0.4 0.1 -0.8 -0.5 -0.3 -0.3 -0.3
Crohns Disease (2012) 2.7 4.3 8.2 2.2 -2.3 -2.2 -1.9 -2.8 -1.2 -2.3 -2.3 -2.5 -2.5 -2.4 -2.5 -2.2 -2.4 -1.2 -2.4 -0.5 -1.9 -1.9 -2.0 -2.9 0.4 -2.4 -1.8 -2.2 -1.9 -1.4 -1.8 -2.3 1.9 -2.0 -2.0 -2.1 -1.8 -1.8
Mean Putamen Volume 2.6 3.0 9.2 0.4 -1.5 -1.1 -1.3 -1.7 -1.5 -2.1 -1.5 -1.5 -1.1 -1.5 -1.2 -0.4 -1.5 -1.3 -2.0 0.6 -2.7 -1.6 0.3 -1.2 2.8 -0.7 -2.6 -1.5 -1.3 -0.4 -2.3 -3.0 1.7 -1.3 -1.5 -3.0 -2.4 -2.4
Fasting Glucose 1.0 1.2 4.7 -0.6 -0.9 -1.3 -0.9 -0.4 -1.5 -0.9 -0.8 -1.3 -1.2 -1.1 -1.5 -1.7 -1.4 -2.2 -1.0 -1.1 -0.3 -1.1 -1.3 -1.2 -1.2 -1.6 0.3 -0.6 0.7 0.4 -1.4 -0.6 -0.9 -1.1 -0.2 -0.4 0.3 0.3
HbA1C 0.2 0.3 1.3 0.4 0.5 0.7 0.5 0.7 1.1 0.5 0.3 0.5 0.3 0.7 0.3 0.4 0.5 -0.4 0.3 0.6 0.5 0.7 -0.0 0.1 -0.6 0.2 0.8 0.5 -0.2 0.4 0.6 0.5 -0.0 0.4 0.0 0.5 0.4 0.3
HDL Cholesterol 0.4 0.6 3.7 -0.5 -0.5 -0.3 -0.4 -0.4 -1.2 -0.7 0.0 -0.6 -0.3 -0.5 0.0 0.2 -0.7 -0.6 -0.6 1.5 -1.1 -0.7 -0.0 -0.1 1.9 0.2 -1.0 -0.7 0.1 -0.4 -1.5 -1.3 -0.0 -0.3 -0.5 -1.3 -0.7 -0.7
LDL Cholesterol 0.9 1.4 4.6 -1.3 0.9 0.2 1.6 1.0 2.1 1.1 0.9 1.1 0.8 1.1 1.0 0.5 1.4 0.9 1.1 0.1 1.4 1.9 0.3 1.1 -1.6 0.7 1.3 0.9 0.3 1.2 1.4 1.6 -0.8 0.8 1.0 1.6 1.3 1.3
Lupus 1.5 2.2 5.4 1.4 -1.5 -1.4 -2.3 -1.8 -0.2 -1.7 -1.6 -1.4 -1.8 -1.6 -1.6 -1.6 -1.5 -1.6 -1.6 -0.8 -1.3 -1.7 -1.8 -1.7 1.0 -1.6 -0.7 -1.7 -0.6 0.8 -1.3 -1.4 1.7 -2.2 -1.8 -1.2 -1.1 -1.2
Neuroticism (2016) 0.3 0.5 1.4 0.1 0.4 0.9 1.1 0.5 0.1 0.9 0.5 1.0 1.2 0.9 0.8 0.9 -0.6 0.6 0.6 0.0 0.6 -0.1 1.0 0.8 0.0 0.9 -0.5 0.6 -0.2 -0.5 1.0 0.9 0.2 0.9 0.3 0.5 0.4 0.5
Primary Biliary Cirrhosis 0.1 0.2 1.9 0.4 -0.1 0.1 -0.4 0.0 1.2 -0.7 0.3 -0.3 -0.2 -0.4 0.0 -0.0 0.3 0.1 -0.2 1.4 -0.4 -0.2 0.8 0.1 0.5 0.1 -0.5 -0.7 0.3 -0.3 -0.7 -0.2 -0.3 0.2 -0.2 -0.2 0.2 0.2
Rheumatoid Arthritis 1.1 1.5 7.0 0.1 -1.2 -0.3 -0.7 -1.0 -1.5 -1.4 -0.4 -1.1 -0.5 -0.9 -0.5 -0.0 -0.9 -0.8 -1.1 0.2 -1.7 -1.4 0.0 -1.7 1.6 -0.1 -2.6 -2.0 -2.3 0.2 -1.5 0.0 0.9 -1.1 -0.9 -2.1 -1.5 -1.5
Schizophrenia (2014) 0.4 0.9 4.6 0.8 -0.7 -0.8 -0.7 -0.7 -1.0 -1.2 -0.7 -1.1 -0.7 -0.9 -1.0 -0.7 -0.9 -1.4 -0.9 -1.4 -1.1 -0.6 -1.1 -1.0 -0.5 -0.7 -1.2 -0.2 -1.3 0.9 -2.1 -1.4 0.3 0.2 0.1 -1.3 -0.5 -0.6
Triglycerides 0.5 0.9 5.7 -1.2 0.1 -0.2 1.0 0.8 0.4 0.9 -0.2 0.2 0.5 0.4 -0.1 -0.2 -0.1 0.8 0.3 -0.6 1.1 0.5 -0.6 0.6 -2.4 -0.2 1.0 1.3 2.1 -0.8 1.3 1.1 -1.2 0.6 1.6 1.2 0.9 0.8
Type 2 Diabetes (T2D) (2012) 1.3 1.5 6.0 2.1 -0.7 -1.1 -0.8 -0.6 -2.0 -1.1 -1.2 -1.3 -1.1 -0.8 -1.4 -1.3 -0.8 -2.5 -1.1 -0.5 -0.6 -0.5 -1.1 -1.7 0.5 -1.6 -0.1 -0.9 -1.2 1.9 -1.1 -0.5 1.5 -1.5 -1.8 -0.4 -0.7 -0.8
Ulcerative Colitis 3.5 5.1 11.0 2.1 -1.8 -2.2 -1.5 -2.4 -1.8 -2.9 -2.1 -2.9 -2.2 -2.0 -2.0 -1.6 -1.8 -2.6 -2.4 -0.3 -2.9 -2.5 -1.1 -3.0 2.1 -1.8 -2.5 -2.6 -0.9 -0.7 -3.3 -3.2 2.1 -2.3 -2.2 -3.1 -2.3 -2.4
Blood Eosinophil Count 3.4 26.5 57.5 4.9 -4.3 -3.7 -4.9 -5.8 -4.2 -6.2 -5.4 -5.8 -4.6 -5.4 -5.3 -4.4 -4.8 -3.9 -5.9 -0.6 -6.0 -5.0 -2.0 -6.9 5.0 -4.9 -7.6 -4.9 -4.3 -2.0 -5.5 -6.3 6.7 -5.1 -4.9 -6.1 -5.3 -5.4
Blood Platelet Count 0.3 3.1 6.0 -0.4 2.2 1.6 1.8 2.0 1.9 2.0 2.1 2.0 1.7 1.9 2.1 2.0 2.0 1.8 2.1 0.2 1.7 1.3 2.4 2.2 -0.3 2.3 1.6 1.7 1.2 -0.1 1.7 1.4 -1.3 2.4 1.8 1.2 1.7 1.8
Blood Red Count 2.9 28.0 45.4 3.0 -6.2 -6.1 -6.7 -6.1 -4.6 -6.3 -6.3 -6.3 -6.6 -6.7 -6.5 -6.3 -6.2 -2.0 -6.2 -5.5 -5.1 -5.0 -6.0 -5.8 -0.7 -6.2 -5.0 -6.2 -1.7 -4.4 -3.5 -4.9 3.4 -5.3 -4.2 -4.7 -4.1 -4.0
Blood White Count 0.6 4.7 12.0 -0.6 -2.5 -3.5 -2.9 -2.5 -1.0 -2.5 -2.4 -2.7 -3.2 -3.0 -2.9 -3.2 -3.0 -0.6 -2.5 -2.2 -1.6 -2.1 -3.0 -2.5 -1.5 -2.9 -0.7 -2.4 -0.5 -0.4 -1.4 -1.6 0.2 -1.9 -1.2 -1.4 -0.7 -0.7
Heel T-Score 0.1 1.0 2.5 0.2 -1.5 -0.7 -1.4 -1.3 -0.1 -1.2 -0.8 -1.3 -1.0 -1.2 -1.0 -0.9 -1.4 -0.8 -1.0 0.4 -1.0 -1.4 -1.6 -1.4 -0.7 -1.0 -1.0 -1.4 0.2 -0.7 -1.3 -0.8 0.5 -0.8 -1.0 -0.7 -0.6 -0.6
BMI 0.3 1.5 6.4 0.3 -0.8 -1.5 -1.4 -1.0 -1.4 -1.1 -1.5 -1.2 -0.6 -1.1 -0.8 -0.4 -1.1 -0.6 -1.3 0.2 -1.5 -0.5 -0.1 -0.3 1.6 -0.7 -1.6 -1.3 0.4 -2.5 -0.2 -1.2 1.9 -1.2 -1.2 -1.4 -1.8 -1.8
Height 1.2 22.9 46.8 1.0 -6.0 -6.4 -4.9 -5.0 -2.2 -5.3 -6.3 -6.0 -6.5 -5.5 -6.6 -6.4 -5.1 -4.8 -5.9 -3.5 -4.0 -4.4 -6.4 -5.6 -3.3 -6.8 -3.5 -4.5 -1.7 -1.3 -2.5 -3.9 2.8 -5.8 -2.8 -3.4 -3.6 -3.7
Waist Hip Ratio (WHR) 0.2 1.0 2.4 -0.5 0.9 1.3 1.6 1.3 0.3 1.1 1.3 0.9 1.3 1.2 1.2 1.2 1.4 0.2 1.0 -0.9 0.9 0.5 0.9 0.9 -0.4 1.4 0.0 0.8 0.0 0.5 0.8 0.4 -1.0 1.2 1.4 0.5 1.0 1.0
Systolic Blood Pressure 0.1 0.3 1.7 1.3 0.3 0.2 0.3 -0.1 -0.7 -0.1 -0.1 0.2 0.2 0.2 0.3 0.4 -0.1 -0.5 0.1 -0.4 -0.2 -0.3 0.5 0.3 1.3 0.3 -0.7 0.2 -0.3 -0.9 0.1 0.4 1.0 -0.0 -1.2 -0.1 -0.5 -0.6
Smoking Status 0.9 2.2 6.7 0.2 -1.3 -2.0 -0.7 -1.2 -0.8 -1.4 -1.3 -1.4 -0.4 -0.8 -0.9 0.1 -1.1 -1.5 -1.5 -1.5 -2.4 -2.0 -0.1 -1.1 0.7 -0.2 -2.2 -1.4 1.0 -2.0 -2.4 -2.4 0.9 -0.9 -0.6 -2.6 -2.2 -2.2
Allergy or Eczema 2.1 5.6 14.4 3.5 -1.2 -0.6 -1.6 -2.5 -1.0 -3.2 -1.2 -2.4 -2.4 -2.5 -2.0 -2.0 -1.5 -2.5 -2.3 -0.0 -2.7 -2.2 -1.1 -3.8 3.0 -1.8 -2.7 -3.1 -2.4 -0.5 -3.5 -3.1 2.8 -2.2 -2.8 -3.1 -1.4 -1.5
Cardiovascular Disease 0.1 0.4 1.1 0.7 1.1 1.0 0.5 0.1 0.4 0.5 0.5 0.9 0.8 0.7 0.9 0.7 0.2 -0.1 0.9 0.1 0.4 0.6 0.2 0.7 1.0 0.7 0.1 0.4 0.3 -0.4 -0.1 0.7 1.0 0.2 -0.1 0.7 0.3 0.3
Hypothyroidism (self reported) 0.6 1.3 6.3 -0.9 0.3 0.5 1.0 0.5 -2.5 0.5 0.6 0.8 1.8 1.1 1.3 2.2 0.7 -2.0 0.4 0.7 -0.6 1.2 2.1 0.5 0.9 1.6 -1.7 1.0 -0.4 0.4 -0.5 -0.7 0.3 0.4 0.3 -1.1 -1.1 -1.1
Respiratory disease 2.6 5.7 10.4 1.5 -2.6 -1.8 -2.0 -2.8 -1.4 -2.8 -2.7 -3.0 -2.9 -2.9 -3.1 -2.9 -2.6 -1.4 -2.9 -1.3 -2.3 -3.2 -2.4 -3.2 0.5 -3.0 -2.6 -2.5 -1.3 -1.7 -2.0 -2.5 2.3 -2.6 -2.1 -2.2 -2.0 -2.0
Type 2 Diabetes (T2D) (2018) 0.2 0.3 1.4 -0.7 -0.2 0.3 -0.1 0.1 -0.5 -0.6 0.2 -0.3 0.2 -0.3 0.2 0.3 0.8 0.7 -0.2 -0.4 -0.7 0.1 0.4 -0.1 1.2 0.3 -0.8 -0.4 -0.6 -0.1 -0.8 -0.8 0.4 -0.0 -0.9 -0.8 -0.6 -0.5
Lung FEV1/FVC ratio 0.1 0.4 2.1 0.5 0.5 0.1 0.1 1.0 0.9 0.5 0.3 0.2 0.5 0.5 0.6 0.5 0.8 -0.5 0.2 0.6 0.0 0.5 0.8 0.9 0.9 0.4 0.6 0.1 1.5 -1.4 0.4 0.1 -0.0 -0.1 0.2 0.1 0.0 -0.0
Lung FVC 0.2 0.9 3.9 0.2 -0.9 -0.9 0.6 -1.0 0.8 -0.8 -1.1 -1.0 -1.2 -1.3 -1.5 -1.9 -2.0 -0.6 -0.9 0.1 -0.3 -0.5 -1.2 -1.3 -1.3 -1.6 -0.1 -1.1 -0.1 -0.0 -1.0 -0.4 0.1 -1.2 -0.2 -0.2 0.0 -0.0
Neuroticism 1.7 4.0 14.4 -0.1 -2.1 -2.5 -2.1 -2.2 -3.1 -1.7 -2.8 -1.3 -1.0 -1.3 -1.4 -0.6 -2.3 -1.4 -1.9 -1.9 -2.3 -1.3 -1.3 -0.8 0.4 -1.4 -3.8 -1.5 -1.9 -1.8 -1.8 -1.1 2.6 -2.2 -2.2 -1.5 -3.2 -3.1
Chronotype (morning person) 0.2 0.4 1.6 -0.5 0.9 0.6 0.4 0.5 0.4 0.4 -0.5 0.2 0.3 0.2 -0.1 -0.1 0.4 0.9 0.2 0.8 0.8 -0.2 -0.4 1.1 0.4 -0.4 1.0 0.4 0.5 -0.0 1.2 1.1 0.4 0.3 0.3 1.2 0.3 0.3
Hair Pigment 0.0 0.9 2.2 -0.2 0.8 1.2 0.3 0.9 -0.3 1.0 1.0 1.1 1.1 0.8 0.9 0.8 0.4 1.4 1.1 1.1 1.1 1.5 0.9 0.3 -0.1 1.0 0.5 0.2 -0.5 -0.2 0.9 1.0 -1.1 1.4 1.4 1.0 1.2 1.2
Tanning 0.2 1.8 5.6 0.7 -1.6 -2.0 -0.7 -1.4 -1.1 -1.5 -0.9 -1.7 -1.4 -1.5 -1.6 -1.8 -1.8 -1.8 -1.3 -0.6 -1.0 -1.6 -1.0 -2.1 -1.6 -1.4 -0.5 -1.0 1.5 -1.0 -2.4 -1.6 -0.9 -1.0 -0.3 -1.3 0.1 0.1
Hand grip strength (left) 0.9 2.4 5.7 1.6 -1.9 -2.2 -1.1 -1.3 -0.6 -1.7 -2.4 -1.5 -1.8 -1.8 -1.9 -1.5 -1.4 -1.9 -1.9 -1.8 -1.6 -1.3 -1.4 -0.9 -0.6 -2.0 -1.1 -1.4 0.1 -1.2 -0.6 -1.2 1.3 -2.1 -1.2 -1.1 -2.0 -2.0
Number of treatments/medications taken 0.4 0.7 4.2 1.0 0.6 0.6 0.4 0.1 -0.9 -0.1 -0.6 -0.0 -0.1 0.1 -0.2 0.3 0.4 -1.0 -0.4 -0.8 -0.2 0.2 0.4 -0.1 1.0 -0.2 0.4 0.5 -1.9 2.0 0.8 0.1 2.1 -0.2 -1.9 -0.3 -1.0 -1.0
Average weekly spirits intake 0.2 0.3 1.4 0.7 0.6 -0.0 0.1 -0.1 -0.2 -0.1 0.6 -0.0 0.0 0.1 0.4 0.5 0.0 -0.6 0.2 0.5 -0.3 -0.3 1.2 -0.3 1.1 0.7 0.1 0.1 0.8 -0.4 -0.9 -0.7 0.1 0.4 -0.5 -0.9 0.2 0.1
Sensitivity / hurt feelings 3.3 5.6 15.6 -0.8 -3.1 -2.8 -2.7 -2.8 -1.6 -2.5 -2.6 -2.4 -2.1 -2.6 -2.5 -2.1 -4.0 -1.1 -2.6 -1.8 -2.6 -2.9 -2.7 -2.5 -1.4 -2.2 -3.8 -1.7 -1.8 -0.3 -2.9 -2.5 1.0 -2.2 -1.3 -2.5 -2.1 -2.1
Frequency of depressed mood in last 2 weeks 3.1 4.3 11.4 -0.1 -2.3 -2.1 -1.1 -2.0 -2.3 -2.1 -2.6 -1.7 -1.4 -1.6 -1.8 -1.0 -1.9 -1.8 -2.5 -3.4 -2.9 -2.4 -1.9 -0.9 0.9 -1.5 -2.8 -1.9 -0.1 -1.0 -1.7 -2.1 2.1 -2.4 -2.3 -2.6 -3.2 -3.2
Hearing difficulty/problems: Yes 0.5 0.8 2.2 0.6 -0.6 -1.1 -0.5 -1.0 -0.9 -0.8 -0.8 -0.7 -0.6 -0.9 -0.7 -0.6 -0.1 -1.3 -0.8 0.4 -0.9 -1.1 0.2 -1.0 1.0 -0.8 -0.9 -1.1 -0.9 -0.6 -1.5 -0.7 1.2 -1.1 -1.2 -0.7 -0.9 -0.9
Relative age of first facial hair 0.2 0.5 1.5 1.1 -0.2 -0.2 -0.5 -0.5 -0.3 -0.7 -0.6 -0.4 -1.0 -1.0 -0.8 -1.1 -0.4 -0.2 -0.5 -0.9 -0.5 -0.0 -1.2 -0.6 0.7 -1.0 0.2 -1.2 -0.1 0.1 -0.4 -0.0 0.9 -1.0 -1.0 -0.1 -0.4 -0.4
Other serious medical condition/disability diagnosed by doctor 6.2 8.1 13.0 1.6 -2.6 -3.3 -2.8 -3.4 -2.2 -3.6 -2.8 -3.1 -2.8 -3.0 -2.9 -2.4 -3.1 -1.9 -3.3 -1.4 -3.4 -2.9 -1.8 -3.6 1.5 -2.6 -3.3 -3.3 -2.7 0.0 -3.4 -3.4 2.5 -2.7 -3.5 -3.5 -2.8 -2.8
Ever used hormone-replacement therapy (HRT) 1.5 1.9 4.8 -0.3 -2.1 -1.4 -2.1 -1.9 -1.9 -1.0 -1.4 -1.5 -1.3 -1.6 -1.8 -1.9 -2.2 0.3 -1.6 -2.2 -0.6 -1.4 -1.5 -1.8 -1.3 -1.6 -1.4 -0.6 -1.9 0.8 -0.4 -0.8 0.0 -1.0 -0.5 -0.7 -0.4 -0.3
Ever had hysterectomy (womb removed) 4.6 5.2 11.6 0.6 -1.8 -2.8 -3.4 -2.8 -1.3 -2.6 -2.2 -3.1 -2.9 -3.2 -3.0 -3.4 -2.2 -1.1 -2.6 -1.3 -1.7 -2.8 -3.4 -3.2 0.4 -2.9 -0.6 -2.7 -1.5 0.8 -1.9 -2.2 1.4 -2.0 -1.9 -2.0 -0.5 -0.5
Systolic blood pressure, automated reading 0.1 0.2 1.6 0.8 -0.0 -0.4 0.5 -0.0 -1.1 0.0 -0.2 -0.4 0.2 0.2 0.0 0.3 -0.2 -0.6 -0.2 0.5 -0.2 -0.8 0.6 0.5 0.2 0.1 -0.2 0.2 0.8 -1.3 -0.0 -0.1 -0.2 0.2 -0.2 -0.4 -0.2 -0.3
Eye problems/disorders: Diabetes related eye disease 2.1 2.3 6.1 -0.4 2.1 2.4 1.4 2.3 1.4 1.6 1.8 1.8 1.8 1.5 1.8 1.5 2.5 1.2 1.8 -0.6 1.4 1.8 1.0 1.9 0.1 1.7 1.7 1.3 1.2 -0.1 1.5 1.4 -0.4 1.4 0.7 1.3 1.2 1.2
Angina 1.5 2.0 4.8 -0.1 -1.1 -1.4 -1.4 -1.9 -2.2 -1.2 -1.5 -1.4 -1.4 -1.3 -1.0 -0.6 -1.0 0.1 -1.6 -0.7 -1.8 -1.2 -0.6 -0.7 1.4 -0.7 -1.4 -1.0 -1.8 1.1 -1.2 -1.6 1.7 -1.2 -2.1 -1.8 -2.2 -2.0
Medication for hormone replacement therapy 4.1 4.6 10.1 0.3 -2.9 -2.9 -1.6 -2.8 -1.5 -2.2 -2.7 -2.4 -2.2 -2.3 -2.6 -2.3 -2.2 -1.6 -2.8 -2.7 -2.2 -3.2 -1.6 -1.9 -0.9 -2.4 -2.3 -1.7 -1.0 -1.0 -1.6 -2.3 0.6 -2.4 -1.2 -2.1 -2.3 -2.3
Vitamin and mineral supplements 0.6 0.7 4.2 -0.3 0.5 0.1 0.6 1.0 0.5 0.6 0.4 0.4 1.3 0.8 0.7 1.1 0.5 -0.6 0.5 1.7 0.2 0.7 2.0 1.1 0.1 0.8 -0.1 0.6 1.6 -1.8 -0.1 0.1 -0.8 0.6 1.4 0.2 0.1 0.0
Supplements: Zinc 0.5 0.6 2.0 1.2 -0.1 -0.9 -1.0 -1.2 -0.6 -0.9 -0.6 -0.5 -1.2 -0.7 -0.8 -0.8 -0.1 0.4 -0.7 -0.7 -0.5 0.2 -1.4 -1.3 0.6 -0.7 0.3 -0.6 -0.1 0.3 0.2 -0.6 1.2 -0.3 -1.1 -0.5 -0.3 -0.3
Medication: Co-codamol 0.1 0.1 1.2 0.0 0.5 0.4 0.3 0.0 -0.1 0.4 -0.1 0.2 0.4 0.4 -0.1 0.2 0.0 -0.6 -0.1 0.1 0.2 -0.1 -0.1 0.4 -0.1 0.1 0.5 0.4 0.3 1.1 0.4 0.2 0.2 0.2 0.4 0.0 0.2 0.1
Medication: Metformin 0.1 0.2 2.7 -0.2 -0.0 0.5 -0.1 0.1 -0.8 -0.2 0.2 -0.3 0.4 -0.4 0.0 -0.2 0.4 1.6 -0.2 -0.8 -0.1 0.2 -0.4 -0.2 0.5 0.1 -0.3 -0.2 -0.5 -0.3 0.3 -0.3 0.6 0.1 -0.5 -0.3 -0.0 0.1
Diabetes (father) 1.2 1.5 2.8 1.0 -1.0 -1.6 -1.3 -1.6 0.0 -1.6 -1.3 -1.7 -1.4 -1.2 -1.1 -1.1 -1.2 -0.7 -1.4 0.2 -1.5 -0.8 -0.6 -1.0 1.2 -1.2 -0.9 -1.3 -1.1 0.2 -1.5 -1.5 1.0 -1.4 -1.6 -1.4 -1.2 -1.2
Diabetes (mother) 0.4 0.5 2.5 0.7 -0.8 -0.6 0.0 -0.1 -1.3 -0.4 -0.8 -0.2 0.2 0.2 -0.0 0.2 -0.7 -0.6 -0.3 -1.0 -0.9 -1.0 -0.2 0.0 0.0 -0.3 -1.2 -0.2 -0.0 -0.6 -0.7 -0.1 0.7 -1.1 -0.6 -0.1 -1.6 -1.6
Severe depression (siblings) 4.9 5.5 13.9 0.8 -1.9 -1.3 -2.9 -2.5 -1.7 -2.5 -2.7 -1.8 -1.8 -2.1 -1.9 -1.6 -1.4 -1.3 -2.3 -1.8 -2.8 -2.3 -1.4 -1.7 2.7 -2.0 -3.0 -2.5 -1.7 -2.3 -2.1 -2.2 3.7 -3.2 -3.3 -2.3 -3.5 -3.4
Pack years adult smoking proportion 2.7 4.1 9.9 -0.1 -2.1 -2.4 -1.8 -2.4 -1.3 -2.3 -2.0 -2.1 -2.2 -2.1 -1.9 -1.4 -2.4 -0.3 -2.2 -1.7 -2.7 -3.2 -1.9 -1.5 1.1 -1.4 -2.1 -2.3 0.1 -2.4 -2.5 -2.9 1.2 -1.7 -2.0 -2.9 -2.1 -2.1
Impedance of leg (right) 0.5 2.2 5.8 -0.6 1.3 1.9 1.3 1.8 0.9 1.8 1.6 1.6 1.7 1.9 1.5 1.8 1.0 0.7 1.6 0.3 1.7 1.4 1.5 0.8 -1.3 1.9 1.2 1.6 -0.2 1.1 0.6 1.0 -2.3 2.4 1.9 1.1 1.7 1.6
Leg fat-free mass (left) 1.7 8.9 19.1 0.4 -3.3 -4.4 -3.5 -3.4 -1.6 -3.3 -3.9 -3.7 -3.9 -3.8 -4.0 -4.2 -3.4 -2.2 -3.5 -1.9 -2.6 -2.9 -4.0 -2.4 -1.1 -4.4 -2.2 -3.0 -0.6 -1.7 -1.5 -2.0 2.2 -4.0 -2.1 -1.9 -2.3 -2.4
Trunk fat percentage 1.1 4.4 10.8 1.2 -1.8 -2.8 -3.3 -2.0 -2.6 -1.9 -2.8 -2.5 -2.4 -2.6 -2.5 -2.3 -1.8 -2.4 -2.6 -0.7 -1.9 -1.4 -1.2 -1.7 0.5 -2.5 -1.6 -1.9 -1.4 -1.7 -0.8 -2.1 2.6 -2.6 -1.8 -2.1 -1.9 -2.1
Hand grip strength (right) 0.5 1.3 4.5 0.1 -2.1 -1.8 -0.9 -0.8 -1.0 -1.2 -1.8 -1.0 -1.3 -1.4 -1.5 -1.1 -1.2 -1.0 -1.6 -0.8 -1.2 -0.8 -1.0 -0.3 -1.0 -1.5 -1.1 -0.8 0.3 -0.7 -0.1 -1.0 0.4 -1.4 -0.3 -0.8 -1.5 -1.5
Townsend deprivation index at recruitment 1.2 1.8 4.0 1.3 -1.1 -1.8 -1.9 -1.8 -1.2 -1.6 -0.8 -1.8 -1.6 -1.6 -1.2 -1.6 -1.9 -0.5 -1.1 -0.0 -1.1 -1.2 -1.5 -2.0 0.3 -1.3 -1.7 -1.7 -1.0 -0.1 -1.8 -1.2 0.6 -1.1 -0.8 -1.2 -0.1 -0.1
Current tobacco smoking 0.3 0.5 4.5 1.1 -0.3 -0.9 -0.1 -0.7 -0.7 -0.2 -0.1 0.1 0.1 0.1 0.0 0.6 -0.4 -0.2 -0.2 -1.1 -0.9 -0.4 0.1 -0.5 0.5 0.5 -0.5 -0.5 1.4 -2.1 -1.5 -1.0 0.4 0.2 -0.1 -1.1 -0.7 -0.7
Average weekly fortified wine intake 0.2 0.2 1.0 -0.2 0.1 -0.2 -0.4 -0.3 0.4 0.2 -0.1 -0.1 -0.5 -0.4 -0.3 -0.5 -0.4 1.0 -0.0 -0.8 0.4 -0.4 -0.7 -0.3 -0.9 -0.2 0.9 0.7 0.8 -0.0 0.4 0.2 -0.5 0.2 0.2 0.2 0.7 0.7
Maternal smoking around birth 0.1 0.2 1.6 0.7 0.1 -0.1 0.1 -0.3 -1.1 0.2 0.4 0.2 -0.2 -0.3 0.2 -0.3 0.1 1.3 0.1 0.2 0.3 -0.2 0.0 -0.0 0.9 0.1 0.5 0.0 0.3 0.3 0.8 0.1 0.2 0.1 0.0 0.1 0.5 0.6
Fed-up feelings 1.7 3.1 12.0 0.7 -1.4 -2.0 -1.7 -1.6 -3.5 -1.3 -1.7 -1.1 -0.2 -0.8 -0.8 0.0 -1.3 -1.9 -1.5 -1.9 -2.2 -1.3 -0.7 -1.2 0.7 -0.5 -3.2 -1.6 -0.0 -3.3 -2.3 -1.6 1.9 -1.5 -1.8 -2.0 -2.5 -2.5
Frequency of unenthusiasm / disinterest in last 2 weeks 4.4 5.8 14.3 2.2 -1.7 -2.3 -2.6 -1.8 -3.0 -2.4 -3.1 -2.2 -2.0 -2.1 -2.2 -1.7 -1.1 -2.1 -2.6 -3.5 -2.8 -1.7 -2.3 -1.2 2.1 -2.3 -1.9 -2.4 -1.5 -1.0 -1.1 -2.0 3.8 -3.2 -3.2 -2.3 -3.5 -3.6
Relative age voice broke 0.1 0.2 1.3 -0.2 0.1 0.7 0.6 0.4 -1.1 0.3 0.3 0.6 -0.2 0.2 0.3 0.5 0.0 0.0 0.3 -0.6 -0.1 0.5 0.1 0.0 0.4 0.6 -0.2 -0.2 0.9 -0.9 -0.1 0.0 -0.2 0.3 0.2 -0.2 -0.1 -0.1
Taking other prescription medications 1.3 2.0 9.5 1.7 -0.4 0.0 -0.3 -0.9 -2.0 -1.3 -1.2 -1.0 -0.5 -0.8 -0.8 -0.3 -0.2 -1.3 -1.3 -0.9 -1.6 -0.7 -0.3 -1.4 2.0 -0.8 -1.6 -1.1 -2.0 0.6 -0.7 -1.1 3.1 -1.5 -3.0 -1.5 -2.1 -2.1
Age when periods started (menarche) 0.3 0.7 3.5 -0.9 -0.3 0.7 0.1 1.0 0.9 0.7 0.7 0.4 0.5 0.5 0.4 0.3 0.6 1.9 0.4 1.2 0.7 0.9 0.2 0.2 -1.1 0.6 -0.0 0.7 1.1 -0.7 1.3 0.5 -1.4 1.2 1.4 0.5 1.0 1.0
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 2.1 0.0 -0.2 -0.8 -1.1 -1.0 0.5 -0.2 0.2 -0.4 -0.5 -0.7 -0.4 -0.9 0.5 1.0 -0.1 -0.8 0.4 -0.7 -1.5 -1.3 -0.9 -0.4 0.1 -0.4 -1.4 -0.1 0.7 -0.1 -0.1 0.1 0.2 0.1 0.9 1.0
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 5.2 1.3 -0.9 -1.0 -0.9 -1.0 -0.1 -1.1 -0.8 -1.2 -1.2 -1.0 -1.0 -0.9 -0.8 -2.3 -1.1 -0.1 -1.1 -1.1 -0.6 -1.2 -0.4 -1.1 -0.9 -1.7 -0.6 -0.7 -1.6 -1.1 1.0 -1.3 -1.4 -1.2 -0.9 -1.0
Tinnitus: Yes, but not now, but have in the past 1.7 1.8 4.2 -0.1 -2.0 -1.2 -1.0 -1.2 -1.1 -1.6 -1.6 -1.2 -1.3 -1.8 -1.6 -1.3 -1.2 -0.4 -1.6 -1.5 -1.5 -1.1 -1.3 -0.9 -0.4 -1.6 -2.0 -1.8 -1.4 -1.1 -1.1 -1.2 1.0 -1.6 -0.6 -1.1 -1.8 -1.7
Qualifications: CSEs or equivalent 1.5 2.0 5.4 1.5 -1.1 -1.2 -1.6 -1.6 0.1 -1.9 -1.2 -1.7 -1.4 -1.4 -1.2 -1.4 -1.7 -1.0 -1.2 1.2 -1.3 -1.3 -0.4 -1.6 0.8 -1.5 -1.7 -1.8 -2.3 0.9 -1.9 -1.1 1.5 -1.7 -2.0 -1.0 -1.0 -0.9
Serious illness, injury or assault to yourself 3.3 4.0 10.8 -1.0 -2.7 -2.8 -2.4 -3.0 -0.7 -2.3 -2.1 -1.9 -2.6 -2.4 -2.3 -2.4 -3.3 0.0 -2.0 -2.2 -1.6 -2.5 -2.6 -2.1 -2.1 -2.3 -2.3 -1.8 -1.3 -0.4 -1.6 -1.3 -0.1 -1.6 -1.1 -1.2 -1.0 -1.0
High blood pressure 0.3 0.8 2.2 0.7 1.4 0.9 0.4 1.0 -0.1 1.2 0.3 1.3 1.2 1.1 1.0 0.9 0.7 0.7 1.1 -0.5 1.1 1.0 0.7 1.4 0.2 0.7 0.8 1.3 -0.3 0.1 1.4 1.5 0.8 0.6 0.4 1.3 0.4 0.4
Hayfever, allergic rhinitis or eczema 2.0 4.3 10.5 3.2 -1.1 -0.6 -1.3 -2.2 -1.1 -2.7 -1.6 -1.9 -2.2 -2.3 -2.0 -2.0 -0.8 -1.4 -2.2 -0.1 -2.2 -2.0 -0.7 -3.1 3.0 -1.9 -2.0 -2.4 -2.7 -0.3 -1.8 -2.4 3.1 -2.1 -3.0 -2.4 -1.7 -1.7
Multivitamins +/- minerals 0.2 0.3 3.1 -0.1 0.0 0.1 0.1 0.1 0.5 0.1 0.1 0.3 -0.4 0.2 0.0 -0.1 0.3 0.7 0.2 -1.1 0.4 -0.0 -1.3 -0.4 -0.9 -0.0 0.6 0.3 -0.7 1.8 0.5 0.6 0.3 0.2 -0.8 0.5 0.2 0.3
Stomach or abdominal pain in last month 0.2 0.2 1.2 1.1 0.7 0.0 0.3 -0.0 0.5 -0.3 -0.3 -0.4 0.0 -0.3 -0.3 -0.2 0.1 0.2 -0.2 -0.2 -0.2 -0.5 -0.1 -0.1 0.8 -0.1 0.7 -0.2 0.2 0.6 -0.7 -0.5 0.7 0.1 -0.5 -0.5 -0.0 -0.0
Supplements: Glucosamine 2.4 3.1 9.4 -0.2 1.9 2.0 1.6 2.2 0.4 2.3 1.6 2.2 1.8 1.9 1.6 1.7 1.6 0.9 1.8 -0.6 2.2 2.3 1.1 1.4 -0.9 1.6 3.1 2.3 1.2 1.1 2.5 2.4 -1.2 1.9 1.1 2.1 1.6 1.5
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 2.4 1.0 0.5 0.9 0.1 0.2 -0.1 0.3 0.6 0.5 0.9 0.3 0.4 0.4 0.6 0.5 0.4 0.5 0.3 -0.1 1.1 0.1 0.7 0.5 -0.1 0.3 -1.6 1.1 0.0 0.0 -0.4 0.6 0.6 0.1 0.4 0.4
Medication: Atenolol 2.2 2.8 6.1 -0.4 2.0 1.8 0.9 1.9 1.2 1.8 1.5 2.5 2.2 2.1 2.2 2.2 2.2 1.8 2.0 1.2 1.6 1.5 1.0 2.3 0.9 1.9 1.2 1.9 0.0 0.6 2.2 2.0 -0.4 1.7 1.3 2.0 0.8 0.9
Medication: Levothyroxine sodium 1.4 2.4 8.4 -0.5 1.4 1.5 1.8 1.9 -1.1 1.3 1.7 1.8 2.8 2.3 2.3 2.9 1.8 -2.4 1.5 0.8 0.6 2.4 2.7 0.8 0.7 2.4 -0.4 0.8 -0.2 1.0 -0.0 0.7 -0.3 1.3 0.8 0.3 0.2 0.1
Sitting height 0.7 4.6 15.8 -0.2 -2.9 -2.9 -2.1 -2.0 -0.4 -2.2 -3.0 -2.6 -3.0 -2.3 -3.1 -3.1 -2.5 -2.1 -2.5 -2.1 -1.4 -1.9 -4.0 -1.7 -2.9 -3.4 -1.1 -1.7 -0.1 -0.4 -0.2 -0.7 0.1 -2.7 -0.9 -0.6 -1.4 -1.4
Chronic bronchitis/emphysema (father) 1.8 2.1 8.8 3.0 -1.0 -0.4 -1.2 -1.6 -1.4 -1.8 -0.8 -1.4 -1.4 -1.8 -1.2 -1.2 -0.8 -0.8 -1.4 -1.2 -1.7 -1.3 -0.6 -1.5 2.0 -0.9 -1.2 -1.7 -1.0 -0.8 -1.5 -1.7 1.9 -1.3 -2.2 -1.9 -1.2 -1.1
High blood pressure (mother) 1.2 1.7 5.0 -0.2 1.6 2.2 1.5 1.2 -0.2 1.6 0.7 1.8 1.3 1.8 1.3 1.5 1.9 0.3 1.1 -0.2 1.1 1.2 1.3 1.8 1.0 1.1 1.3 1.6 -1.5 2.0 2.1 1.3 1.1 0.4 -0.4 1.0 -0.3 -0.3
Body mass index (BMI) 0.9 4.0 8.2 0.7 -1.7 -2.5 -2.4 -2.0 -2.5 -2.0 -2.6 -2.2 -1.9 -2.4 -2.1 -1.9 -1.6 -1.4 -2.3 -0.9 -2.3 -1.3 -1.2 -1.0 1.4 -2.2 -1.8 -2.2 -0.4 -2.3 -0.9 -1.8 2.9 -2.8 -2.0 -1.9 -2.5 -2.5
Impedance of leg (left) 0.7 3.5 7.7 -0.6 2.0 2.4 1.9 2.5 1.1 2.1 2.3 2.0 2.2 2.3 2.1 2.5 1.8 0.2 2.0 1.1 1.9 2.0 2.3 1.3 -0.5 2.6 1.5 1.9 0.1 1.3 0.5 0.9 -2.4 2.8 2.3 1.0 2.0 1.9
Leg predicted mass (left) 1.6 8.7 18.7 0.5 -3.2 -4.3 -3.5 -3.4 -1.7 -3.2 -3.9 -3.6 -3.9 -3.8 -3.9 -4.1 -3.3 -2.2 -3.5 -1.8 -2.6 -2.8 -3.9 -2.5 -1.0 -4.3 -2.1 -2.9 -0.7 -1.6 -1.4 -2.0 2.2 -4.0 -2.1 -1.9 -2.3 -2.4
Trunk fat mass 1.6 6.9 13.4 1.0 -2.5 -3.6 -3.7 -2.7 -2.9 -2.7 -3.5 -3.3 -3.1 -3.2 -3.2 -3.0 -2.5 -2.6 -3.2 -1.0 -2.5 -2.0 -2.2 -2.2 0.1 -3.3 -2.2 -2.6 -1.3 -2.2 -1.1 -2.4 2.8 -3.3 -2.1 -2.4 -2.4 -2.5
Waist circumference 1.6 5.8 10.4 0.9 -2.3 -3.1 -3.2 -2.3 -3.0 -2.5 -3.2 -2.9 -2.6 -2.9 -2.8 -2.7 -2.0 -2.0 -2.8 -2.0 -2.3 -2.0 -2.5 -1.6 0.5 -3.0 -2.0 -2.5 -0.7 -2.5 -0.9 -2.0 2.7 -3.2 -2.0 -2.0 -2.5 -2.5
Number of incorrect matches in round 0.1 0.2 0.6 -0.1 0.1 -0.0 0.6 -0.8 0.5 0.5 0.4 0.5 0.2 0.2 0.2 -0.1 -0.4 0.5 0.4 0.3 0.5 0.1 0.2 -0.2 -0.1 0.1 -0.1 0.1 -0.8 0.5 -0.0 0.6 -0.2 0.2 0.3 0.6 0.6 0.6
Past tobacco smoking 0.8 1.4 6.2 -0.3 0.7 2.0 1.2 0.9 1.1 1.3 1.2 1.5 0.5 0.9 1.1 0.5 0.7 2.5 1.3 -0.2 1.5 1.4 0.2 1.4 -0.9 0.8 1.3 1.3 0.6 0.6 1.8 1.6 -0.6 0.9 0.6 1.8 1.2 1.3
Alcohol usually taken with meals 0.8 1.2 3.9 -0.9 0.2 0.7 1.2 0.9 -0.6 1.4 0.7 0.9 0.8 0.9 0.7 0.7 -0.1 2.0 0.8 0.6 1.2 1.4 0.4 1.4 -1.2 0.9 1.4 1.6 1.2 0.6 1.7 1.3 -1.8 1.3 1.6 1.2 0.9 0.9
Nervous feelings 0.4 0.7 2.2 0.7 -0.9 -0.8 -1.0 -0.8 -1.3 -0.9 -1.1 -0.8 -0.7 -1.0 -1.2 -1.1 -1.5 -0.1 -0.9 -1.1 -0.5 -0.9 -1.0 -0.7 -0.6 -1.1 -1.0 -0.8 -0.3 -0.9 -0.4 -0.2 0.9 -0.8 -0.8 -0.3 -0.5 -0.5
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 5.9 0.0 -0.4 -0.2 -0.6 -0.1 -1.4 -0.3 -1.0 -0.2 -0.3 -0.1 -0.4 0.1 -0.2 -0.3 -0.7 -2.4 -0.7 -0.4 -0.3 0.2 -0.2 -0.3 -1.1 0.1 -1.0 0.3 0.2 -0.5 0.7 -0.5 -0.4 -0.6 -1.2 -1.2
Hearing difficulty/problems with background noise 0.3 0.5 2.1 -0.7 0.4 -0.0 0.6 0.5 -0.9 0.9 0.8 0.6 1.4 0.9 0.8 0.9 0.5 -0.2 0.7 0.6 0.5 0.3 0.8 0.3 -1.0 0.9 -0.2 0.8 0.8 -0.9 -0.4 0.4 -1.0 0.7 1.1 0.3 0.6 0.5
Hair/balding pattern: Pattern 2 0.8 1.1 4.1 -2.0 0.3 0.6 1.4 1.3 1.3 1.0 0.6 0.9 0.8 0.8 0.8 0.9 0.5 0.3 0.8 0.8 0.7 0.4 0.8 1.7 -1.6 0.8 0.2 1.4 1.2 0.2 0.9 0.6 -1.6 1.0 1.9 0.7 0.7 0.6
Had menopause 0.3 0.4 1.7 -0.4 0.1 -0.1 -1.0 -0.7 -0.4 -0.1 -0.1 -0.3 -0.4 -0.8 -0.7 -1.2 -0.6 0.5 -0.2 -0.4 0.5 -0.5 -0.5 -1.3 -0.1 -0.7 0.2 0.1 -0.8 1.1 -0.4 0.1 0.2 0.1 -0.1 0.2 1.0 1.0
Had other major operations 0.2 0.3 1.5 -0.2 0.6 0.3 0.0 0.6 1.2 -0.0 -0.0 0.0 -0.5 0.1 -0.2 -0.4 1.2 -0.6 -0.1 -0.2 0.4 0.1 -0.2 -0.3 -0.2 -0.4 1.0 0.3 -0.0 0.8 1.1 0.6 0.5 -0.3 -0.8 0.5 0.4 0.4
Forced vital capacity (FVC) 0.4 1.6 7.7 -0.7 -1.6 -1.7 0.2 -0.9 1.2 -0.7 -1.7 -1.2 -1.7 -1.2 -1.9 -2.3 -1.9 -1.2 -1.1 -0.2 -0.1 -0.5 -2.1 -0.8 -2.8 -2.3 -0.5 -0.7 0.1 -0.9 0.0 0.1 -0.7 -1.7 0.7 0.4 -0.0 -0.1
Heel bone mineral density (BMD) T-score, automated (right) 1.2 2.8 5.0 1.5 -1.6 -1.8 -1.8 -1.9 -1.1 -1.7 -1.6 -2.1 -2.0 -1.7 -1.8 -1.5 -1.7 -2.0 -1.8 -0.4 -1.7 -1.7 -1.3 -2.0 -0.1 -1.7 -1.4 -2.1 -1.1 -0.9 -2.1 -1.7 1.4 -1.9 -2.2 -1.8 -1.5 -1.6
Ever unenthusiastic/disinterested for a whole week 0.8 0.9 2.0 -1.1 0.8 0.6 1.3 0.7 -0.0 1.0 0.5 1.3 1.2 1.3 1.1 1.0 1.2 1.4 1.1 -1.4 0.8 1.2 -0.5 1.3 -0.3 0.8 0.3 1.1 1.0 -0.9 1.1 1.4 -0.1 0.6 0.7 1.3 0.1 0.2
Qualifications: None of the above 0.7 1.6 4.2 2.0 -1.0 -0.8 -1.6 -0.9 -1.8 -1.3 -1.3 -1.4 -1.1 -1.5 -1.5 -1.5 -1.1 -0.3 -1.4 -0.6 -1.0 -0.6 -0.7 -1.7 1.3 -1.4 -1.2 -1.1 -1.7 -0.6 -1.1 -1.1 1.6 -1.3 -1.1 -0.9 -0.9 -0.9
Financial difficulties in last 2 years 0.3 0.5 1.9 -0.8 0.7 0.0 0.6 0.6 -0.5 0.2 0.0 0.3 1.0 1.1 0.7 1.2 0.6 -0.8 0.3 0.4 -0.5 0.4 1.4 0.2 1.1 0.8 -0.7 -0.1 0.2 -0.1 -1.2 -0.1 0.4 0.0 -0.4 -0.3 -1.0 -1.0
Mouth/teeth dental problems 0.9 1.3 5.7 -1.1 0.5 0.7 0.3 1.4 1.1 0.7 1.3 0.4 0.3 0.4 0.4 -0.3 1.1 1.5 1.0 0.8 1.3 1.0 -0.3 -0.0 -1.5 0.4 1.8 0.7 2.4 0.3 1.1 1.0 -1.8 1.1 1.4 1.2 2.1 2.1
Heart attack 0.4 0.5 2.3 1.5 0.9 -0.5 -0.5 -0.0 1.0 -0.1 -0.5 0.6 0.3 0.4 0.1 0.3 1.3 -0.4 0.1 -0.2 0.2 -0.6 0.6 0.1 1.4 -0.1 0.9 -0.0 -1.5 1.2 0.4 0.5 1.1 -0.2 -1.1 0.5 -0.5 -0.6
Allergy 3.3 7.5 14.2 -2.9 2.5 1.6 2.2 3.2 1.7 3.6 2.5 2.9 3.0 3.0 2.8 2.6 2.2 2.2 3.1 0.5 3.1 3.0 1.2 3.7 -2.1 2.6 3.8 3.1 2.7 1.6 2.8 3.3 -3.0 2.9 3.0 3.1 2.7 2.6
Pain all over the body in last month 0.9 1.0 4.3 0.4 1.2 1.4 0.9 0.1 -0.5 0.9 1.0 1.2 1.1 1.1 1.4 1.5 1.7 0.6 0.9 -0.1 0.2 0.1 1.6 0.3 2.1 1.3 -0.4 0.7 -1.5 -0.7 0.6 0.3 1.3 0.4 -0.9 -0.1 -0.5 -0.4
Diabetes (self-reported) 0.1 0.1 1.1 -0.3 0.3 -0.3 -0.6 -0.2 -0.4 -0.3 -0.1 0.1 0.1 -0.4 -0.1 -0.2 0.4 0.5 -0.0 -1.1 -0.1 0.2 -0.5 -0.3 0.2 -0.1 0.6 -0.3 -0.3 -0.1 -0.4 -0.1 0.6 -0.1 -0.8 -0.0 -0.0 0.0
Hayfever/allergic rhinitis (self-reported) 1.5 2.0 5.3 0.9 -1.6 -1.1 -1.4 -2.1 -0.4 -2.1 -0.9 -1.7 -2.1 -1.9 -1.6 -1.8 -1.1 -0.1 -1.8 -0.6 -1.7 -2.3 -0.8 -1.6 0.4 -1.3 -1.3 -2.0 -0.2 -0.1 -1.5 -2.2 0.6 -1.1 -1.3 -2.1 -0.6 -0.5
Medication: Ramipril 1.3 1.6 7.1 -0.7 1.5 1.2 1.3 1.8 1.5 1.2 0.4 1.1 0.6 1.0 0.5 0.3 1.1 1.0 1.2 0.1 1.9 0.3 0.0 1.0 -0.4 0.2 2.2 1.6 0.4 1.3 2.7 2.2 -0.3 1.1 0.8 2.3 1.3 1.3
Medication: Simvastatin 0.2 0.3 1.5 0.1 0.8 0.1 0.2 0.1 -0.1 0.5 0.6 0.2 0.4 0.2 0.5 0.3 -0.2 0.6 0.4 1.2 0.4 0.3 0.8 -0.1 0.5 0.5 0.7 0.7 -0.9 1.2 -0.2 -0.1 -0.1 0.5 0.0 -0.1 0.6 0.6
Fluid intelligence score 0.1 0.3 2.7 -0.4 0.1 -0.0 -0.2 -0.2 1.3 0.2 0.6 0.5 0.7 0.6 0.7 0.7 0.5 0.8 0.5 -0.1 -0.0 -0.3 0.0 0.3 -0.4 0.8 0.4 0.2 1.6 -0.8 0.1 0.1 -0.5 0.6 0.1 0.0 0.2 0.2
Illnesses of siblings 1.1 1.6 7.0 -0.4 -1.4 -1.0 -0.9 -1.3 0.4 -0.7 -0.8 -1.6 -1.5 -1.6 -1.7 -2.2 -2.7 0.3 -1.2 -0.8 -0.3 -1.7 -2.1 -1.5 -2.0 -1.6 -0.4 -0.6 0.9 -0.5 -1.5 -0.8 -1.4 -0.7 0.6 -0.5 0.6 0.7
Neuroticism score 1.2 2.4 9.8 -0.4 -1.7 -2.1 -1.3 -1.8 -2.4 -1.5 -1.7 -1.1 -0.4 -1.3 -1.0 -0.4 -2.2 -0.5 -1.3 -1.5 -1.9 -1.5 -0.8 -1.3 -0.0 -0.8 -3.1 -1.6 -0.4 -2.6 -2.0 -1.2 1.4 -1.1 -1.3 -1.5 -2.0 -1.9
Weight 2.3 11.1 20.9 0.9 -3.6 -4.6 -3.8 -3.6 -3.1 -3.6 -4.4 -4.1 -4.0 -4.1 -4.1 -4.0 -3.4 -2.8 -4.0 -2.0 -3.4 -2.9 -3.5 -2.7 -0.2 -4.3 -2.9 -3.5 -0.8 -2.6 -1.8 -2.9 3.0 -4.4 -2.6 -2.9 -3.3 -3.3
Impedance of arm (right) 0.2 0.9 3.3 1.2 -0.6 -0.5 -1.2 -0.5 -0.6 -0.4 -0.9 -0.5 -1.3 -0.6 -1.3 -1.1 -0.4 -0.9 -0.8 -1.7 0.4 -0.5 -1.5 -1.2 -1.3 -1.2 1.3 0.4 -1.6 1.8 0.2 -0.2 -0.2 -0.3 -0.3 0.1 0.2 0.1
Arm fat percentage (right) 1.5 5.8 12.7 1.2 -2.1 -3.0 -3.6 -2.4 -3.1 -2.4 -3.3 -2.7 -2.8 -2.8 -2.8 -2.5 -1.7 -1.9 -2.9 -1.7 -2.3 -1.5 -1.9 -1.7 0.9 -3.0 -1.5 -2.2 -1.5 -1.8 -0.7 -2.1 3.2 -3.2 -2.5 -2.1 -2.7 -2.8
Trunk fat-free mass 1.4 7.8 15.7 -0.3 -3.5 -4.0 -2.7 -3.3 -1.6 -3.2 -3.6 -3.4 -3.4 -3.4 -3.5 -3.6 -3.3 -1.7 -3.3 -1.9 -2.8 -2.8 -3.8 -2.2 -1.2 -3.8 -2.5 -3.1 -0.1 -1.7 -1.5 -2.0 1.6 -3.7 -1.8 -2.0 -2.6 -2.6
Hip circumference 1.8 7.8 15.1 0.7 -3.1 -3.8 -3.6 -3.0 -2.6 -2.9 -3.8 -3.4 -3.4 -3.5 -3.5 -3.6 -2.9 -2.0 -3.3 -1.5 -2.5 -2.6 -3.4 -2.0 0.1 -3.9 -1.9 -2.8 -0.4 -2.6 -1.0 -1.9 2.8 -3.8 -2.4 -1.8 -2.6 -2.7
Time employed in main current job 2.8 3.3 7.0 1.8 -2.3 -2.1 -2.6 -2.0 -1.5 -2.2 -1.8 -1.8 -1.7 -2.5 -1.9 -2.0 -2.1 -1.4 -2.0 -1.9 -1.8 -1.8 -1.4 -2.0 0.8 -1.9 -1.2 -2.6 -0.0 -1.4 -1.6 -1.5 1.2 -2.0 -2.1 -1.5 -1.2 -1.2
Alcohol intake versus 10 years previously 0.3 0.4 3.0 -0.2 0.2 -0.4 -0.0 0.3 0.3 0.5 0.3 0.2 0.1 0.3 0.2 -0.2 0.1 0.5 0.5 0.3 1.0 0.7 -0.0 0.3 -1.7 -0.1 -0.1 0.2 -0.2 0.6 1.0 1.1 -0.8 0.3 0.7 1.1 1.1 1.1
Father’s age at death 0.3 0.4 2.8 0.3 -0.3 0.5 -0.6 -0.3 0.4 0.2 0.3 0.2 -0.0 -0.3 -0.1 -0.4 -0.6 1.7 0.0 -1.4 0.2 -0.3 -1.1 -0.2 -1.0 -0.1 0.8 0.1 0.7 0.9 0.1 0.2 -1.1 0.1 0.5 0.3 0.5 0.5
Worrier / anxious feelings 0.4 0.7 3.6 -1.3 -1.7 -1.3 -0.9 -1.0 -0.7 -0.7 -0.9 -0.5 -0.4 -0.7 -0.4 -0.1 -1.8 -0.8 -0.8 -0.6 -0.9 -0.2 -0.0 -0.2 -1.0 -0.4 -1.9 -0.3 -0.9 -0.6 -0.2 -0.4 -0.2 -0.6 -0.3 -0.5 -1.1 -1.1
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 3.3 -0.9 -1.0 -1.3 -1.0 -0.9 -0.6 -0.9 -1.4 -0.3 -0.3 -0.7 -0.7 -0.1 -0.6 -1.5 -1.1 -1.6 -1.2 -0.9 -1.0 -0.5 -0.1 -0.6 -1.7 -0.8 -0.7 -0.4 -0.6 -0.5 1.2 -1.1 -1.3 -0.9 -1.8 -1.8
Falls in the last year 0.6 0.8 4.5 0.9 -0.4 -0.6 -0.1 -0.5 -0.5 -0.8 -1.4 -0.4 -0.5 -0.5 -0.6 -0.3 0.4 -1.3 -1.0 -0.9 -1.0 -0.3 -0.5 0.1 0.8 -0.7 -0.9 -0.5 -0.9 -0.9 0.2 -0.5 2.1 -1.3 -1.5 -0.7 -1.7 -1.7
Hair/balding pattern: Pattern 3 0.2 0.3 2.9 1.7 0.8 0.5 -1.0 -0.3 1.0 -0.2 -0.2 0.3 0.0 0.1 -0.2 -0.2 0.4 0.4 -0.1 -0.2 -0.0 -1.2 0.1 0.2 1.1 -0.3 0.4 -0.5 -0.1 0.0 0.3 0.3 1.1 -0.2 -0.5 0.2 -0.1 -0.2
Number of live births 0.4 0.6 1.5 -0.7 0.7 1.0 0.8 0.9 0.8 0.8 0.5 0.6 0.6 0.4 0.3 0.1 0.9 0.5 0.7 0.3 1.2 0.9 0.4 0.5 -0.5 0.1 0.9 0.7 -0.4 0.8 1.2 1.1 -0.4 0.7 0.8 1.2 1.0 1.0
Forced expiratory volume in 1-second (FEV1) 0.3 1.1 7.2 -1.0 -1.0 -1.2 0.5 -0.2 1.7 -0.2 -1.2 -0.8 -1.2 -0.8 -1.3 -1.8 -1.2 -1.2 -0.6 0.1 0.3 0.1 -1.5 0.0 -2.7 -1.8 0.0 -0.2 0.7 -0.9 0.4 0.5 -1.0 -1.3 1.1 0.8 0.3 0.2
Pulse rate 0.4 0.6 2.4 0.8 -0.7 -0.7 -0.8 -0.9 -1.4 -0.6 -0.8 -0.5 -1.0 -0.9 -0.7 -0.8 -0.4 1.4 -0.7 -1.5 -0.4 -0.1 -0.5 -0.2 0.1 -0.8 0.4 -0.7 -0.2 0.1 1.1 -0.0 0.8 -0.5 -1.5 -0.3 -0.6 -0.5
Happiness 0.8 1.0 4.4 -0.4 -1.1 -1.2 -0.4 -1.4 0.3 -1.1 -1.0 -0.9 -0.9 -0.9 -1.0 -1.1 -1.5 0.2 -0.9 -2.1 -0.9 -2.0 -1.0 -0.3 -1.2 -0.9 -1.6 -0.5 0.0 0.2 -1.0 -0.7 0.4 -0.7 -0.6 -0.7 -0.5 -0.4
Noisy workplace 1.5 1.9 6.5 1.2 2.6 1.3 1.2 1.9 1.8 1.2 1.4 1.1 1.5 1.2 1.2 0.8 2.3 -0.2 1.7 2.5 1.7 1.4 0.6 0.8 1.1 0.7 1.7 0.8 -0.6 -0.3 0.5 1.5 0.3 0.7 0.8 1.7 1.5 1.3
Qualifications: A levels/AS levels or equivalent 0.2 0.6 1.8 0.5 -0.2 -1.0 -1.0 -1.0 0.8 -0.8 -1.0 -0.6 -0.8 -0.8 -1.0 -1.0 -0.4 -0.3 -0.7 -0.7 -0.3 -1.1 -1.3 -0.9 -0.1 -1.2 0.9 -0.4 0.2 0.2 -0.3 -0.1 0.5 -0.7 -1.1 0.0 -0.5 -0.4
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.0 3.6 -0.4 0.9 0.2 0.6 0.7 -0.7 1.1 0.3 1.4 1.0 1.1 0.7 0.8 0.7 0.5 0.8 -1.5 1.2 0.1 0.1 0.5 -1.4 0.5 1.8 1.3 0.1 1.9 1.8 1.3 -1.0 0.7 0.9 1.4 0.6 0.6
Mouth/teeth dental problems: Dentures 0.4 0.7 3.3 0.5 -0.3 -0.3 -0.6 -1.2 -1.4 -0.6 -0.4 -0.6 -0.1 -0.5 -0.1 0.0 0.1 -0.8 -0.7 0.4 -0.8 -0.9 -0.1 -0.4 1.7 -0.0 -1.1 -0.7 -1.8 -0.3 -0.2 -1.1 1.6 -0.7 -1.3 -1.1 -0.9 -0.9
Asthma 1.5 2.9 7.3 0.8 -1.7 -1.4 -1.5 -2.1 -0.9 -1.9 -2.2 -2.0 -2.0 -1.8 -2.3 -2.0 -2.3 -1.7 -2.1 0.2 -1.4 -2.0 -1.3 -2.7 -0.4 -2.2 -2.0 -1.6 -1.3 -1.1 -1.6 -1.6 1.2 -1.9 -1.2 -1.4 -1.4 -1.5
Medication: Ibuprofen (e.g. Nurofen) 1.8 2.3 6.2 -1.5 1.2 1.1 2.5 1.1 1.1 1.8 1.1 1.9 1.8 2.0 1.5 1.6 0.7 1.0 1.7 1.5 1.7 1.4 0.8 1.5 -1.9 1.2 0.5 1.7 0.8 -0.7 1.9 2.3 -1.4 1.4 1.7 2.1 1.0 1.0
Medication: Cholesterol lowering 0.6 0.9 2.5 -0.5 1.2 0.8 1.4 1.2 0.7 1.2 0.9 1.0 0.9 1.1 1.2 1.3 1.2 0.7 1.1 0.4 0.8 0.5 1.3 1.6 -0.0 1.2 0.7 1.1 -1.0 1.5 0.8 0.9 -0.2 1.1 0.4 0.7 0.5 0.5
Depression (self-reported) 0.2 0.2 1.4 1.2 0.3 -0.1 0.2 0.1 -0.5 0.1 -0.5 -0.1 -0.2 -0.1 -0.4 -0.4 0.2 -0.0 -0.1 -0.2 0.2 0.9 -0.9 0.0 0.5 -0.5 0.8 -0.1 0.7 -0.8 0.9 0.2 0.9 -0.4 -0.0 0.2 -0.1 -0.1
Medication: Lansoprazole 0.3 0.3 1.7 0.1 0.8 -0.1 -0.9 0.1 1.3 -0.1 -0.2 -0.4 -0.4 -0.1 -0.2 -0.4 -0.0 -0.3 0.1 0.8 0.4 -0.8 -1.3 -0.1 -0.0 -0.3 1.2 -0.3 -0.8 0.6 0.2 0.3 0.6 -0.1 -0.9 0.4 0.6 0.5
Prospective memory result 0.4 0.5 2.3 0.8 0.1 0.5 -1.1 -0.9 0.0 -0.4 -0.3 -0.2 -0.4 -0.7 -0.5 -0.3 -0.7 -0.5 -0.5 -0.5 -0.6 0.2 -0.6 -0.7 1.2 -0.2 -0.3 -0.7 -1.5 0.3 -1.2 -0.8 1.1 -0.4 -0.7 -0.8 -0.5 -0.6
Lung cancer (father) 0.4 0.5 1.4 -0.6 -1.1 -0.9 -0.5 0.4 -0.6 -0.2 -0.2 -0.9 -0.5 -0.6 -0.6 -1.0 -0.9 0.8 -0.2 -1.2 0.3 -0.2 -0.6 0.1 -0.6 -0.8 -0.3 -0.2 0.8 -1.0 0.6 0.3 -1.2 -0.0 1.1 0.6 0.7 0.7
Illnesses of mother 0.9 1.1 5.5 0.2 -0.6 -1.3 -1.3 -0.6 1.7 -1.2 -0.2 -1.4 -1.3 -1.4 -1.1 -1.4 -0.8 -0.8 -0.8 2.3 -0.5 -1.3 -0.4 -1.7 -0.1 -1.0 -0.0 -0.9 0.7 -0.0 -1.6 -1.2 -0.7 -0.3 0.1 -0.8 0.7 0.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.2 7.1 -0.6 -0.8 -1.1 0.9 -0.1 2.2 -0.3 -1.0 -0.6 -1.2 -0.5 -1.2 -1.8 -1.0 -1.4 -0.5 0.2 0.4 0.1 -1.6 -0.2 -2.7 -1.7 0.2 -0.2 1.3 -1.2 0.2 0.6 -1.4 -1.1 1.3 0.9 0.7 0.6
Pulse wave Arterial Stiffness index 1.3 1.5 4.0 -0.8 -1.4 -0.9 -1.7 -1.5 -0.9 -1.4 -0.7 -1.2 -1.4 -1.5 -1.1 -1.3 -0.9 -0.5 -1.2 -1.4 -1.4 -1.7 -2.0 -1.2 0.1 -1.0 -0.6 -1.4 -0.3 0.6 -1.8 -1.4 0.1 -1.5 -1.0 -1.4 -0.9 -0.9
Impedance of arm (left) 0.1 0.6 4.5 0.5 0.2 0.1 -0.8 0.1 0.4 0.3 -0.0 0.1 -0.6 -0.0 -0.6 -0.6 0.1 -0.4 -0.0 -0.5 1.1 -0.1 -0.6 -0.8 -1.6 -0.4 1.6 1.0 -1.5 2.1 0.3 0.3 -1.0 0.6 0.3 0.6 1.2 1.1
Arm fat mass (right) 1.5 6.1 12.0 0.6 -2.5 -3.4 -3.5 -2.6 -3.0 -2.5 -3.3 -2.9 -3.0 -3.1 -3.0 -2.9 -2.3 -1.8 -3.0 -1.4 -2.3 -1.8 -2.5 -1.8 0.2 -3.2 -1.9 -2.5 -1.0 -2.1 -0.9 -2.0 2.6 -3.3 -2.1 -2.0 -2.4 -2.5
Trunk predicted mass 1.4 7.7 15.8 -0.4 -3.5 -4.0 -2.7 -3.3 -1.5 -3.1 -3.6 -3.4 -3.4 -3.4 -3.5 -3.6 -3.4 -1.7 -3.3 -1.9 -2.8 -2.8 -3.9 -2.2 -1.3 -3.8 -2.5 -3.1 -0.2 -1.6 -1.5 -2.0 1.5 -3.7 -1.8 -2.0 -2.5 -2.5
Standing height 1.3 13.0 28.7 0.4 -4.7 -5.2 -3.7 -3.9 -1.6 -3.9 -4.6 -4.5 -4.8 -4.2 -5.0 -5.0 -4.5 -3.4 -4.4 -2.7 -2.8 -3.7 -5.4 -4.0 -3.5 -5.1 -2.6 -3.2 -0.9 -1.0 -2.2 -2.6 0.6 -4.1 -1.5 -2.3 -2.1 -2.2
Length of working week for main job 2.0 2.3 6.7 2.1 -2.2 -2.0 -2.6 -1.6 -0.6 -1.6 -1.6 -1.3 -1.7 -1.7 -1.7 -2.3 -1.2 -0.6 -1.5 -1.8 -0.8 -0.1 -1.7 -1.9 -0.8 -2.2 -1.4 -1.9 -1.6 -0.5 -0.3 -0.6 0.7 -2.0 -0.6 -0.2 -0.7 -0.7
Exposure to tobacco smoke at home 0.3 0.4 1.7 -0.4 0.4 0.6 0.4 1.1 0.2 0.4 0.4 0.9 0.6 0.6 0.8 1.0 1.3 -0.3 0.7 0.1 0.3 1.1 0.4 0.3 0.9 0.7 0.3 -0.1 0.3 -0.8 0.5 0.6 0.4 0.3 -0.1 0.6 -0.1 -0.1
Breastfed as a baby 0.3 0.3 1.9 0.2 0.0 -0.3 -1.0 -1.0 0.3 -0.5 0.0 -0.2 -0.4 -0.7 -0.3 -0.6 -0.3 1.4 -0.1 -0.2 -0.2 -1.2 -0.8 -0.7 0.3 -0.2 0.2 -0.6 1.0 -0.8 -0.8 -0.4 -0.2 0.3 0.1 -0.2 0.4 0.5
Tense / ‘highly strung’ 0.3 0.6 4.9 -0.4 -0.8 0.3 -0.2 -0.2 -1.8 -0.4 -0.0 0.3 0.2 -0.1 0.4 0.7 0.0 0.4 -0.0 -1.5 -0.7 -0.5 -0.1 0.1 0.6 0.6 -2.2 -0.2 -1.2 -0.6 -0.3 -0.3 1.1 -0.1 -0.8 -0.5 -1.0 -0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 3.1 4.8 13.1 1.1 -1.9 -2.5 -1.5 -1.9 -3.6 -1.8 -2.7 -2.4 -1.6 -1.9 -1.8 -0.8 -2.0 -2.3 -2.5 -1.5 -2.9 -0.9 -1.0 -1.6 1.6 -1.6 -2.3 -2.1 -0.4 -2.9 -1.6 -2.5 2.7 -2.3 -2.2 -2.8 -3.4 -3.5
Hair/balding pattern: Pattern 4 0.2 0.6 4.5 0.8 -1.1 -0.6 -0.9 -0.5 -1.3 -0.5 -1.0 -0.6 -0.9 -0.6 -0.7 -0.7 -0.6 -0.5 -0.6 0.2 -0.1 0.6 -0.3 -1.0 -0.1 -1.0 -0.2 -0.7 -2.1 0.7 0.5 0.1 0.7 -0.9 -0.4 0.4 -0.7 -0.7
Birth weight of first child 3.6 6.5 11.2 -0.3 -3.4 -2.9 -3.3 -2.7 -1.4 -2.7 -3.1 -2.8 -2.8 -3.2 -2.9 -2.8 -3.0 -1.6 -3.0 -2.2 -2.5 -2.8 -2.7 -2.7 -0.6 -3.0 -3.3 -2.3 -2.6 0.2 -2.0 -2.2 1.8 -3.0 -2.0 -2.0 -2.5 -2.4
Peak expiratory flow (PEF) 0.4 0.9 3.0 -0.6 -1.1 -1.2 0.5 -0.1 1.0 -0.6 -1.2 -1.3 -1.1 -1.1 -1.3 -1.5 -1.0 -1.4 -1.0 0.3 -0.4 -0.5 -0.9 0.1 -1.4 -1.5 -0.6 -0.6 1.2 -1.7 -0.1 -0.3 -0.3 -1.3 0.5 -0.1 -0.3 -0.3
Pulse wave reflection index 0.9 1.2 4.7 -2.2 1.0 1.6 0.2 1.3 0.5 1.0 1.5 1.4 1.5 1.4 1.6 1.5 1.0 0.5 1.3 0.2 0.5 0.9 0.3 1.3 0.5 1.6 0.2 1.0 0.5 0.6 -0.2 0.6 -1.1 0.9 1.1 0.6 0.6 0.6
Ever highly irritable/argumentative for 2 days 0.6 0.8 2.3 0.1 -1.1 -1.1 0.1 -1.4 -0.5 -0.9 -0.7 -1.3 -0.6 -1.1 -0.9 -1.2 -1.5 0.4 -0.9 -0.0 -0.9 -1.0 -0.6 -0.5 0.5 -1.0 -1.3 -1.2 -0.3 -0.5 -1.5 -0.8 0.2 -0.9 -0.5 -0.8 -0.4 -0.4
Loud music exposure frequency 0.4 0.4 2.1 0.4 -0.3 0.0 0.5 0.5 1.3 -0.4 -0.5 -0.6 -0.7 -0.8 -0.7 -1.2 0.1 -0.8 -0.2 -0.2 0.2 -0.1 -1.5 -0.2 -0.2 -1.2 0.3 -1.0 0.1 -0.8 0.7 0.2 0.7 -1.1 0.2 0.6 0.2 0.2
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 1.6 -1.1 -0.3 -0.4 0.4 -0.1 0.7 0.3 0.2 0.4 0.3 0.5 0.4 0.2 0.5 1.1 0.3 0.2 0.3 0.1 0.1 0.3 -1.1 0.2 0.6 0.3 0.0 1.3 1.1 0.9 -0.8 0.3 -0.1 0.7 0.0 0.2
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 1.8 0.0 0.6 0.1 0.4 0.4 -0.3 0.1 -0.2 0.4 0.4 0.2 0.4 0.9 0.4 -0.7 0.1 -0.1 -0.5 0.3 1.3 1.1 1.0 0.5 -0.3 0.2 0.5 -0.9 -0.4 -0.5 0.2 0.1 0.1 -0.6 -0.9 -0.9
Blood clot in the leg (DVT) 0.2 0.2 1.7 -0.9 -0.1 -0.3 -0.0 -0.2 0.4 -0.2 0.5 0.2 -0.1 0.0 0.2 0.3 -0.3 -0.9 0.1 1.3 -0.1 0.5 0.8 -0.6 -0.4 0.3 -0.7 -0.1 0.7 -0.6 -0.9 -0.3 -0.2 0.2 0.2 -0.2 0.3 0.3
Medication: Paracetamol 0.1 0.2 1.9 0.2 -0.2 0.2 0.4 -0.2 -1.4 0.3 0.1 0.2 0.6 0.1 0.3 0.3 -0.7 -0.3 0.0 -0.0 -0.0 0.9 0.5 -0.2 0.1 0.3 -0.8 -0.1 -0.4 -0.0 0.1 0.3 0.4 0.0 -0.2 -0.1 -0.0 -0.0
Headache pain in last month 0.9 1.6 3.7 -0.3 -1.8 -1.9 -1.3 -1.8 -1.5 -1.2 -1.5 -1.1 -1.1 -1.1 -1.1 -0.8 -1.3 -1.2 -1.5 -1.1 -1.5 -1.7 -1.1 -0.8 -0.6 -1.0 -1.3 -1.4 0.5 -1.8 -0.9 -1.1 0.2 -1.4 -1.1 -1.3 -1.4 -1.5
Medication for cholesterol, blood pressure or diabetes 0.3 0.4 1.7 -0.5 -1.0 -0.6 -0.9 -0.6 -0.2 -0.8 -0.3 -0.7 -0.7 -0.7 -0.8 -1.1 -0.7 -0.1 -0.5 0.2 -0.2 -0.3 -1.3 -1.3 -0.6 -0.8 -0.4 -0.5 1.3 -0.8 -0.5 -0.1 -0.4 -0.5 -0.3 -0.1 0.3 0.3
Glaucoma (self-reported) 0.5 0.6 4.5 0.1 0.5 0.4 0.7 0.8 0.7 0.4 0.2 -0.3 0.2 0.1 -0.3 -0.4 0.4 -0.9 0.1 0.1 1.2 0.4 -0.4 -0.6 -2.1 -0.4 1.1 1.1 -0.5 1.6 1.2 0.6 -0.8 0.5 0.9 0.8 1.1 1.1
Gout (self-reported) 0.8 1.1 6.0 -0.1 -0.6 -1.2 -1.0 -0.7 1.4 -0.8 -0.9 -1.2 -1.4 -1.2 -1.4 -1.8 -1.0 0.8 -0.7 0.3 0.4 -1.4 -1.8 -0.9 -2.4 -1.6 0.0 -0.5 -0.8 0.6 0.2 0.1 -0.8 -0.3 0.5 0.4 0.9 0.9
Hypothyroidism/myxoedema (self-reported) 0.9 1.8 5.5 -1.5 0.8 0.9 1.6 1.1 -1.6 1.1 1.3 1.5 2.2 1.7 1.8 2.3 1.2 -2.1 1.1 1.9 0.4 2.2 2.1 0.7 -0.0 1.8 -0.8 1.4 -0.2 1.2 -0.1 0.4 -0.4 0.9 1.0 0.0 0.0 -0.1
Medication: Amlodipine 0.2 0.3 2.3 0.2 0.5 0.5 0.1 0.1 0.0 0.3 0.3 0.7 0.4 0.5 0.4 0.6 0.3 0.6 0.3 -1.0 0.3 -0.0 1.5 0.0 -0.0 0.8 0.4 0.3 -1.0 1.1 0.2 -0.0 0.1 0.6 -0.5 -0.2 0.0 0.1
Medication: Ventolin 100micrograms inhaler 1.7 2.1 4.8 -0.0 -1.8 -1.2 -1.6 -1.7 -1.4 -1.5 -2.1 -1.5 -1.8 -1.6 -2.1 -1.8 -2.2 -1.3 -1.9 -1.1 -1.2 -1.3 -1.7 -1.3 -0.9 -2.0 -1.5 -0.7 -0.7 -0.9 -0.4 -1.1 1.2 -1.7 -0.9 -1.0 -1.4 -1.5
Birth weight 2.4 5.3 12.8 -0.4 -3.6 -3.5 -2.8 -2.6 -1.4 -2.6 -2.9 -2.6 -2.7 -2.6 -2.9 -2.7 -2.7 -1.3 -3.1 -1.2 -2.3 -2.7 -2.8 -1.9 -1.8 -2.9 -2.7 -1.9 -1.1 0.1 -1.0 -2.2 0.4 -2.6 -0.7 -1.9 -2.0 -2.0
Chronic bronchitis/emphysema (mother) 0.2 0.3 1.3 0.1 0.2 0.3 -0.3 0.1 -1.1 -0.2 -0.1 -0.3 -0.8 -0.8 -0.7 -1.0 -0.4 0.4 -0.3 -0.4 0.3 0.8 -0.9 -0.4 -0.4 -0.8 0.9 -0.1 0.6 0.2 0.4 0.1 0.1 -0.2 0.1 0.3 0.6 0.6
High blood pressure (siblings) 0.6 0.8 3.4 -0.1 1.0 1.2 0.4 0.9 0.3 0.5 0.6 1.0 0.9 1.2 1.1 1.5 1.7 -0.1 0.8 0.1 0.2 1.1 1.9 1.4 1.3 1.1 -0.3 0.7 -1.1 0.3 1.1 0.2 1.0 0.5 -0.0 0.1 -0.4 -0.4
Forced vital capacity (FVC), Best measure 0.5 2.0 6.9 -0.4 -1.6 -1.8 0.4 -1.3 1.7 -1.1 -1.8 -1.3 -2.0 -1.2 -2.0 -2.4 -2.1 -1.7 -1.4 0.1 -0.4 -0.9 -2.2 -1.3 -2.6 -2.3 -0.8 -1.1 0.7 -1.5 -0.7 -0.4 -0.8 -1.8 0.5 -0.1 -0.0 -0.2
Body fat percentage 0.9 3.7 8.9 1.1 -1.4 -2.5 -3.0 -1.7 -2.7 -1.8 -2.6 -2.3 -2.0 -2.3 -2.2 -1.9 -1.4 -2.1 -2.3 -0.6 -1.8 -1.1 -1.0 -1.4 0.9 -2.2 -1.4 -1.8 -1.3 -1.7 -0.8 -1.9 2.7 -2.3 -1.8 -2.0 -2.0 -2.1
Leg fat percentage (right) 1.1 3.9 8.9 0.6 -1.9 -2.5 -2.6 -1.8 -3.0 -1.9 -2.6 -2.3 -1.8 -2.3 -2.1 -1.7 -1.5 -1.3 -2.3 -1.4 -2.1 -1.2 -1.2 -1.0 1.0 -2.1 -1.9 -2.2 -0.4 -2.6 -0.9 -2.0 2.6 -2.4 -1.8 -2.0 -2.4 -2.4
Arm fat-free mass (right) 0.8 4.0 9.8 -0.9 -2.4 -3.1 -2.1 -2.2 -0.8 -2.2 -2.5 -2.7 -2.4 -2.5 -2.5 -2.9 -2.8 -1.2 -2.2 -0.3 -1.8 -1.9 -2.7 -1.7 -1.3 -2.8 -2.3 -2.4 -0.0 -1.4 -1.2 -1.2 0.8 -2.6 -0.8 -1.2 -1.2 -1.2
Exposure to tobacco smoke outside home 3.6 4.9 8.4 -1.3 2.3 2.3 1.8 2.6 2.2 2.6 2.4 2.2 2.4 2.3 2.1 1.8 1.7 1.6 2.4 2.2 2.9 2.2 2.0 1.7 -1.6 1.9 2.1 2.1 -0.3 2.1 1.9 2.6 -2.2 2.6 2.6 2.7 2.8 2.7
Comparative body size at age 10 0.1 0.2 1.3 0.6 0.0 -0.2 -0.7 -0.5 -0.5 -0.2 -0.7 -0.1 -0.4 -0.4 -0.4 -0.3 0.1 0.2 -0.5 -0.3 -0.5 -0.3 -0.2 0.8 0.6 -0.4 0.1 0.2 1.2 -0.5 -0.2 -0.4 0.6 -0.6 -0.4 -0.4 -0.8 -0.8
Number of full brothers 0.4 0.5 1.6 0.5 0.8 1.0 0.9 1.1 0.2 0.3 0.7 0.8 1.1 0.7 0.9 1.3 0.8 -0.0 0.7 0.0 -0.1 0.5 1.2 0.7 0.8 1.0 -0.2 0.7 -0.2 1.2 -0.9 0.1 -0.1 0.7 0.2 0.0 -0.2 -0.2
Worry too long after embarrassment 1.0 1.6 5.1 0.6 -1.4 -1.7 -1.5 -1.7 -1.3 -1.2 -1.7 -1.1 -1.1 -1.2 -1.3 -1.5 -1.8 0.3 -1.1 -1.5 -0.8 -2.2 -2.0 -0.9 -0.2 -1.5 -1.2 -1.2 -0.2 -1.8 -0.4 -0.2 1.2 -1.3 -1.4 -0.3 -1.0 -0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 2.5 3.3 10.6 0.3 -1.6 -2.2 -2.1 -2.0 -1.9 -2.1 -2.4 -2.4 -2.4 -2.4 -2.5 -2.5 -2.1 0.2 -2.2 -2.1 -1.5 -1.7 -3.3 -1.7 0.1 -2.5 -0.3 -1.4 0.3 -0.6 -0.7 -1.4 1.3 -1.7 -1.3 -1.2 -1.2 -1.1
Wheeze or whistling in the chest in last year 1.2 2.2 4.2 0.7 -1.0 -1.0 -1.5 -1.6 -1.6 -1.9 -1.5 -1.1 -1.6 -1.2 -1.5 -1.1 -0.7 -2.0 -1.6 -1.2 -1.6 -1.4 -1.6 -1.8 0.8 -1.4 -1.6 -1.8 -1.6 -0.6 -1.4 -1.4 2.0 -1.7 -2.0 -1.5 -1.7 -1.7
Number of children fathered 0.8 0.9 3.4 0.4 -0.7 -1.5 -0.8 -0.7 0.7 -0.8 -1.5 -1.3 -1.2 -1.3 -1.4 -1.8 -0.1 0.3 -1.0 0.3 -0.1 -0.9 -1.3 -0.2 -0.2 -1.8 0.4 -0.6 -1.6 1.1 0.8 0.0 0.7 -1.4 -0.7 0.3 -0.5 -0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 2.4 -0.8 -0.3 0.8 0.6 0.7 0.1 0.2 0.3 0.7 0.6 0.3 0.4 0.4 -0.4 -0.1 0.5 -1.4 0.6 0.2 -0.9 0.3 -1.5 0.4 -0.6 0.2 0.0 -0.0 0.9 0.8 -0.8 0.4 1.0 0.8 0.4 0.4
Age at first live birth 0.4 0.7 2.9 -1.0 0.9 1.5 0.3 0.8 1.7 0.7 0.8 1.1 0.8 0.6 0.9 0.9 0.7 0.6 0.8 -0.2 0.6 -0.2 1.6 0.6 -0.5 0.9 0.3 1.1 0.0 0.8 0.6 0.8 -0.7 0.8 0.4 0.7 0.4 0.4
Pulse wave peak to peak time 0.7 0.8 2.3 0.9 1.0 0.4 1.3 1.1 0.8 1.0 0.3 0.7 0.8 1.0 0.6 0.7 0.3 0.3 0.8 1.4 1.2 1.3 1.4 0.7 -0.3 0.4 0.4 1.0 0.1 -0.5 1.5 1.1 -0.1 1.1 0.9 1.1 0.8 0.8
Health satisfaction 0.6 0.8 4.0 -1.2 -0.8 -1.1 -0.9 -1.4 0.5 -0.9 -0.9 -0.5 -0.6 -0.5 -0.5 -0.5 -0.1 -0.7 -0.6 -0.9 -0.5 -1.4 -1.5 -0.8 -1.4 -0.6 -1.3 -0.3 -2.0 0.4 -0.2 -0.3 0.1 -0.7 -0.8 -0.4 -0.7 -0.7
Shortness of breath walking on level ground 0.2 0.3 2.7 -0.1 0.1 0.0 0.1 -0.0 -0.8 -0.1 0.3 0.5 0.2 0.2 0.5 0.3 0.5 -0.6 0.3 0.5 0.2 -0.1 0.2 0.1 0.4 0.2 -0.8 0.8 -1.6 0.7 0.4 0.5 0.9 -0.3 -0.8 0.4 -0.1 -0.0
Qualifications: College or University degree 0.1 0.3 1.8 -1.3 -0.0 0.0 0.6 0.1 -0.0 0.2 -0.2 0.4 -0.1 0.4 0.2 0.4 0.5 0.7 0.1 -0.6 0.0 -0.5 -0.5 1.3 0.1 0.2 0.4 0.9 1.3 -0.2 1.2 0.4 -0.1 0.3 0.2 0.2 -0.4 -0.4
Eye problems/disorders: None of the above 0.6 0.7 6.8 -0.5 -0.7 -0.3 1.1 0.1 0.6 0.2 -0.3 0.5 0.0 0.2 0.2 0.3 -0.0 1.1 0.1 -1.0 -0.1 -0.4 0.4 1.1 -0.8 0.2 -0.5 0.1 2.2 -2.6 1.4 0.4 -0.4 0.1 1.1 0.4 -0.4 -0.4
Mouth/teeth dental problems: Loose teeth 0.5 0.5 2.8 1.3 0.6 -0.0 -0.6 -0.4 0.8 -0.5 -0.6 -0.6 -0.4 -0.3 -0.4 -0.2 0.5 -0.8 -0.3 0.1 -0.7 -0.6 -0.5 -0.2 1.6 -0.5 0.1 -0.4 -1.1 0.3 -1.0 -0.6 1.7 -0.8 -1.0 -0.5 -1.0 -1.0
Emphysema/chronic bronchitis 3.5 3.9 9.6 0.3 -2.7 -1.9 -1.8 -2.1 -1.5 -2.6 -2.5 -1.7 -2.3 -2.2 -2.4 -2.4 -2.0 -0.7 -2.4 -2.8 -1.9 -2.2 -3.1 -2.1 -0.6 -2.5 -2.1 -1.9 -1.6 -0.3 -1.0 -1.3 1.4 -2.3 -1.8 -1.1 -1.9 -1.8
Medication for pain relief, constipation, heartburn 0.5 0.9 2.2 0.1 -1.3 -0.7 -1.0 -0.8 1.5 -1.2 -0.7 -1.1 -1.3 -1.2 -1.3 -1.5 -1.0 0.4 -1.0 -0.1 -0.8 -1.5 -1.2 -1.3 -0.7 -1.2 -0.2 -1.0 0.7 -0.0 -1.3 -1.1 -0.8 -0.7 0.1 -0.7 -0.2 -0.1
Neck or shoulder pain in last month 0.4 0.6 3.0 -0.1 -0.9 -0.8 -0.6 -0.7 0.1 -0.8 -0.7 -0.9 -0.8 -1.0 -1.0 -0.9 -1.2 -0.8 -0.7 -0.7 -0.4 -0.1 -1.2 -1.0 -1.7 -0.8 -0.8 -0.8 -0.1 -1.2 -1.0 -0.3 -0.2 -0.5 -0.1 -0.3 -0.1 -0.1
Medication: Blood pressure 0.4 0.7 5.3 0.8 0.8 0.6 -0.0 0.9 0.3 0.8 -0.1 0.9 0.7 0.8 0.5 0.8 1.0 0.6 0.5 -1.3 0.7 0.5 1.0 1.2 0.1 0.4 0.2 0.7 -2.3 1.0 1.7 0.9 0.6 0.5 0.3 0.8 -0.3 -0.3
Angina (self-reported) 1.1 1.4 3.6 -0.1 -0.9 -1.2 -1.2 -1.6 -1.9 -1.0 -1.3 -1.2 -1.3 -1.2 -0.9 -0.6 -0.9 0.3 -1.3 -0.6 -1.5 -1.0 -0.5 -0.7 1.2 -0.6 -1.0 -0.8 -1.6 1.1 -1.0 -1.3 1.5 -1.0 -1.9 -1.5 -1.8 -1.6
Migraine (self-reported) 2.0 2.5 8.1 -1.2 1.2 1.7 2.6 2.0 0.8 2.0 1.0 1.9 2.2 1.7 1.6 1.9 1.7 0.4 1.7 -0.5 1.5 0.7 1.5 2.8 -1.3 1.5 1.3 2.2 2.0 -0.3 2.0 2.0 -0.8 1.3 1.4 1.8 0.4 0.4
Medication: Ibuprofen 0.9 1.0 3.6 -0.7 0.6 0.5 1.8 0.6 0.0 1.3 0.2 1.3 1.3 1.4 0.9 1.1 0.2 0.7 1.0 0.2 1.1 1.1 0.5 1.1 -1.7 0.7 0.2 1.6 0.2 -0.8 1.9 1.8 -0.5 0.8 0.8 1.5 0.1 0.1
Medication: Allopurinol 1.2 1.6 4.7 0.2 -0.9 -1.4 -1.2 -1.2 0.5 -1.5 -1.4 -1.7 -1.7 -1.8 -1.9 -2.2 -1.4 -0.4 -1.4 0.5 -0.5 -2.0 -1.9 -1.6 -1.7 -2.0 -0.8 -1.2 -0.9 0.9 -0.9 -0.8 -0.0 -1.0 -0.1 -0.4 0.1 0.1
Medication: Omeprazole 0.3 0.4 2.0 1.1 0.4 0.0 -0.1 0.1 -1.2 -0.3 -0.5 -0.4 -0.3 -0.3 -0.2 -0.1 -0.1 0.1 -0.2 -1.1 -0.4 0.5 -0.2 1.1 1.4 -0.3 0.2 -0.4 -0.7 0.6 -0.0 -0.0 1.2 -0.4 -1.1 -0.2 -0.7 -0.7
Medication: Seretide 50 evohaler 0.7 0.8 2.2 1.2 -0.0 -0.6 -0.9 -0.5 0.2 -1.2 -1.0 -1.0 -0.8 -0.9 -1.2 -0.8 -0.4 -1.3 -1.0 -0.5 -0.7 -1.3 -0.3 -1.5 0.7 -1.0 0.3 -1.2 0.8 -1.1 -1.4 -0.9 1.0 -0.5 -1.1 -0.9 -0.5 -0.5
Mean time to correctly identify matches 0.2 0.4 1.4 -0.0 -0.4 -0.5 -0.3 -0.9 0.3 -0.6 -0.5 -0.3 -0.5 -0.5 -0.7 -0.6 -0.5 -0.7 -0.8 -0.7 -0.5 -1.1 -0.2 -1.1 0.3 -0.6 0.2 -0.3 -0.1 1.2 -0.8 -0.4 0.4 -0.6 -1.0 -0.5 -0.4 -0.5
Heart disease (mother) 0.7 0.8 3.3 -1.8 0.0 0.7 0.7 0.9 0.2 1.1 0.8 0.6 0.7 0.7 1.1 1.2 0.9 0.9 0.6 -0.4 0.6 0.8 0.9 1.4 -0.5 1.3 0.2 0.7 0.0 1.1 1.7 0.4 -1.3 1.1 1.1 0.2 0.4 0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.4 2.8 6.0 -0.0 1.9 1.9 1.6 1.8 0.7 1.5 2.2 1.8 2.3 1.8 2.0 2.0 1.5 2.3 1.9 1.3 1.3 2.0 2.0 1.7 -0.5 2.3 1.2 1.9 1.7 -0.2 1.0 0.9 -1.6 2.5 1.7 0.8 1.6 1.7
Whole body fat mass 1.4 5.9 12.1 0.7 -2.2 -3.4 -3.5 -2.4 -2.7 -2.5 -3.3 -3.0 -2.9 -3.0 -3.0 -2.8 -2.2 -2.3 -3.0 -0.9 -2.3 -1.8 -2.1 -1.9 0.4 -3.1 -1.9 -2.5 -1.2 -2.0 -1.0 -2.2 2.8 -3.1 -2.1 -2.2 -2.3 -2.4
Leg fat mass (right) 1.2 4.8 9.5 0.6 -2.0 -3.0 -3.0 -2.0 -2.5 -2.2 -3.1 -2.8 -2.5 -2.7 -2.7 -2.5 -1.9 -1.7 -2.7 -1.2 -2.1 -1.6 -1.9 -1.3 0.5 -2.8 -1.8 -2.4 -0.7 -2.3 -0.9 -1.9 2.7 -2.9 -1.8 -1.9 -2.3 -2.4
Arm predicted mass (right) 0.8 4.0 9.9 -0.6 -2.4 -3.2 -2.2 -2.3 -1.2 -2.2 -2.4 -2.6 -2.4 -2.6 -2.5 -2.8 -2.7 -1.3 -2.2 -0.5 -1.9 -1.8 -2.6 -1.7 -1.1 -2.7 -2.3 -2.5 -0.0 -1.6 -1.3 -1.3 1.0 -2.6 -0.9 -1.4 -1.3 -1.3
Pulse rate, automated reading 0.8 2.7 7.2 0.2 -1.5 -1.8 -2.2 -2.2 -1.5 -2.0 -1.3 -1.9 -2.7 -2.5 -2.4 -2.7 -2.5 0.4 -1.8 -1.8 -0.8 -1.8 -2.0 -1.9 -1.4 -2.1 -0.2 -1.7 -0.8 1.2 -0.3 -1.5 -0.2 -0.6 -0.7 -1.3 0.3 0.4
Alcohol intake frequency. 0.1 0.3 2.0 0.2 -0.7 -0.6 -1.3 -0.7 -0.6 -0.5 -0.5 -0.3 -0.8 -0.6 -0.5 -0.8 -0.2 0.5 -0.5 -0.4 -0.1 -0.3 -0.2 -0.0 -0.5 -0.7 -0.6 -0.4 -1.4 0.4 0.3 0.0 0.3 -0.8 -0.7 0.1 -0.3 -0.2
Comparative height size at age 10 1.0 5.7 11.7 1.0 -2.3 -3.2 -2.0 -2.5 -0.5 -2.7 -3.0 -3.1 -3.0 -2.6 -3.4 -3.3 -2.6 -3.2 -2.9 -1.2 -1.8 -3.0 -3.3 -2.6 -1.5 -3.4 -1.0 -2.1 -1.6 0.9 -2.3 -1.9 1.2 -2.8 -1.8 -1.7 -1.3 -1.5
Number of full sisters 0.9 1.1 4.0 0.3 -0.8 -2.0 -0.4 -0.4 -0.5 -1.1 -1.5 -1.5 -1.6 -1.3 -1.6 -1.5 -0.4 -1.6 -1.3 -0.4 -0.7 -1.1 -1.0 -0.6 0.2 -1.7 0.0 -0.7 0.7 -1.4 -0.1 -1.0 0.4 -1.1 -0.2 -0.7 -0.5 -0.6
Suffer from ‘nerves’ 0.3 0.5 2.4 -0.5 0.9 0.6 0.1 0.8 -0.4 0.5 0.2 0.9 0.5 0.4 0.5 0.3 0.6 0.6 0.7 -0.5 0.8 1.2 -0.5 0.4 -0.6 0.2 1.2 0.3 -0.1 0.7 0.6 1.5 0.6 0.2 -0.7 1.3 0.4 0.5
Overall health rating 0.9 1.8 7.3 0.7 -1.0 -1.3 -1.2 -1.4 -1.7 -1.5 -1.6 -1.4 -1.4 -1.5 -1.5 -1.2 -0.9 -1.0 -1.6 -0.9 -0.9 -1.6 -1.8 -1.5 0.5 -1.6 -1.3 -1.1 -2.7 0.1 -0.2 -0.9 1.8 -1.2 -2.0 -1.0 -1.2 -1.2
Chest pain or discomfort 0.2 0.3 2.4 0.6 0.1 -0.2 -0.4 -0.7 -1.5 -0.6 0.1 -0.0 -0.4 -0.5 -0.2 -0.4 0.1 0.2 -0.2 0.8 -0.2 0.3 -0.1 -1.2 0.9 -0.2 -0.0 -1.0 -0.8 0.0 -0.6 0.1 0.6 -0.1 -1.2 -0.0 0.1 0.1
Had major operations 0.1 0.1 0.7 0.5 -0.2 -0.5 0.6 -0.3 -0.0 -0.1 0.0 -0.2 -0.2 -0.2 0.1 0.0 0.2 -0.1 -0.1 -0.8 -0.2 -0.1 -0.1 0.2 0.3 -0.0 -0.0 -0.5 -0.3 -0.4 0.3 -0.1 0.2 -0.3 -0.3 -0.0 -0.3 -0.3
Age at last live birth 0.9 1.4 3.4 -0.9 1.0 1.5 0.3 1.3 1.8 1.1 1.3 1.1 0.7 0.8 1.1 0.8 0.8 1.1 1.3 0.0 1.4 0.9 1.1 0.8 -1.1 1.0 1.0 1.5 0.8 0.4 1.5 1.2 -1.5 1.4 1.7 1.3 1.5 1.5
Family relationship satisfaction 0.4 0.5 4.3 -0.7 -0.6 -0.9 -0.4 -0.7 1.0 -0.3 -0.5 -0.3 -0.1 -0.2 -0.5 -0.6 -0.3 0.4 -0.2 -1.5 0.2 -0.5 -1.5 -0.9 -2.1 -0.6 -0.5 0.1 -0.0 0.2 0.0 0.2 -0.7 -0.0 0.7 0.4 0.3 0.3
Leg pain on walking 0.8 1.0 3.6 0.9 0.0 -1.2 -0.4 -1.4 -0.1 -1.1 -0.9 -1.1 -1.0 -1.1 -0.9 -1.0 -0.4 -1.6 -0.9 0.2 -1.0 -0.9 -1.1 -0.9 0.8 -1.1 -0.5 -0.8 0.0 -1.0 -1.0 -1.0 1.9 -1.4 -1.6 -1.1 -0.8 -0.8
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 3.3 -0.3 0.6 -0.1 1.7 0.9 0.4 0.9 1.4 1.3 1.4 1.5 1.7 1.8 0.5 0.0 1.5 1.1 0.6 1.1 1.7 1.4 -1.1 1.8 -0.3 0.6 1.5 -1.2 0.1 1.0 -1.5 1.1 0.8 0.6 0.7 0.7
Commuting to job workplace: Car/motor vehicle 1.1 1.2 4.5 -0.2 1.1 1.6 0.7 2.1 0.1 1.3 1.1 1.2 1.4 1.1 1.2 1.4 0.9 0.0 1.1 0.0 0.9 0.8 1.5 2.1 0.1 1.4 1.2 1.2 -0.1 1.4 0.6 0.9 -1.1 1.2 1.0 0.8 0.7 0.6
Illness, injury, bereavement, stress in last 2 years 4.0 4.9 11.7 -0.2 2.4 3.4 1.6 3.1 0.9 2.4 2.9 2.2 2.3 2.0 2.6 2.1 3.1 1.8 2.5 2.5 2.4 2.8 2.1 2.7 1.5 2.5 2.0 2.1 0.6 -0.0 2.5 2.0 -0.8 2.3 1.7 1.9 2.2 2.2
Medication: Aspirin 0.9 1.2 4.8 1.8 -0.3 -0.5 -1.7 -0.8 -2.2 -0.9 -0.8 -0.5 -0.8 -0.8 -0.5 -0.1 0.0 -0.7 -0.8 -1.8 -0.8 -0.7 -0.3 -0.4 1.8 -0.4 -1.2 -0.5 -1.4 -0.5 0.2 -0.8 2.2 -0.6 -1.7 -0.9 -1.2 -1.2
Supplements: Vitamin C 0.7 0.8 3.4 -0.2 -0.6 -0.4 -0.8 -1.4 0.2 -0.9 -0.8 -0.3 -1.6 -0.8 -0.8 -1.3 -0.7 0.8 -0.6 -1.4 -0.4 -1.1 -1.9 -0.9 0.5 -1.1 -0.5 -1.1 -1.4 0.3 -0.1 -0.0 0.7 -1.2 -1.2 0.1 -0.5 -0.4
Knee pain experienced in last month 0.5 0.7 4.2 1.7 -0.2 -0.5 -0.7 0.4 -1.5 -0.6 -0.8 -0.8 -0.2 -0.3 -0.7 -0.4 0.5 -2.1 -0.7 -0.9 -0.6 0.2 -0.3 -0.4 0.8 -0.7 -0.2 -0.7 0.3 -1.1 -0.8 -0.7 1.7 -1.0 -0.9 -0.6 -1.0 -1.1
Hypertension (Self-reported) 0.3 0.7 1.7 0.6 1.3 0.9 0.3 0.7 -0.3 1.0 0.4 1.3 1.2 1.0 1.1 1.0 0.8 0.7 1.1 -0.5 0.9 0.7 0.7 1.1 0.6 0.9 0.6 1.0 -0.4 0.5 1.0 1.2 0.8 0.6 0.2 1.1 0.3 0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.2 1.5 3.3 0.3 1.7 1.8 0.7 1.4 0.7 1.2 1.4 1.1 1.3 1.2 1.5 1.5 1.0 0.3 1.4 1.4 1.0 1.5 1.4 1.7 1.4 1.6 1.2 1.3 -0.1 1.6 0.9 0.7 -0.0 1.3 0.7 0.7 0.9 0.9
Illnesses of father: Heart disease 0.2 0.2 1.1 -0.0 0.0 -0.7 -0.6 -0.3 0.2 -0.1 -1.0 -0.2 -0.2 -0.3 -0.8 -0.6 0.1 -0.1 -0.4 -0.6 -0.1 0.1 -0.2 -0.2 -0.6 -0.9 0.4 0.3 -0.6 0.1 0.7 0.1 0.6 -0.5 0.1 0.2 -0.6 -0.6
Illnesses of siblings: Diabetes 0.4 0.5 2.4 -0.0 -0.3 -0.5 -0.6 -0.6 -1.6 -0.8 -0.6 -0.6 -0.6 -0.9 -0.4 -0.3 -0.3 -0.3 -0.6 0.1 -0.9 -0.6 -0.8 -0.3 0.9 -0.5 -0.5 -0.6 -0.6 -0.1 -0.2 -0.8 1.2 -0.7 -0.8 -0.8 -1.0 -1.0
Smoking status: Previous 1.2 1.7 6.0 0.2 -1.0 -1.7 -0.7 -1.0 -1.3 -1.5 -1.3 -1.6 -0.6 -0.9 -1.0 -0.4 -0.9 -2.5 -1.4 0.4 -1.9 -1.6 0.1 -1.0 1.4 -0.8 -2.1 -1.4 -0.6 -0.6 -1.7 -1.7 1.1 -1.2 -1.0 -2.0 -1.6 -1.7
Forced expiratory volume in 1-second (FEV1), predicted 1.2 2.4 9.5 -2.0 0.8 0.7 2.0 1.8 2.7 1.5 0.7 1.2 0.8 1.4 0.7 0.4 1.0 -0.2 1.2 1.9 1.5 1.4 0.1 1.6 -2.3 0.4 1.9 1.6 3.1 -0.2 1.1 1.5 -2.2 0.9 2.6 1.8 1.5 1.5
Whole body fat-free mass 1.3 7.4 15.8 -0.0 -3.2 -4.0 -2.9 -3.2 -1.5 -3.0 -3.5 -3.4 -3.4 -3.4 -3.5 -3.7 -3.2 -1.9 -3.2 -1.6 -2.6 -2.6 -3.6 -2.3 -1.1 -3.8 -2.4 -3.0 -0.3 -1.6 -1.6 -1.9 1.7 -3.6 -1.7 -1.9 -2.2 -2.3
Leg fat-free mass (right) 1.5 8.1 17.5 0.5 -3.0 -4.2 -3.3 -3.2 -1.6 -3.2 -3.7 -3.6 -3.8 -3.6 -3.7 -4.0 -3.0 -2.3 -3.4 -1.5 -2.6 -2.6 -3.8 -2.4 -0.7 -4.1 -2.0 -2.9 -0.5 -1.6 -1.5 -2.0 2.2 -3.9 -2.1 -1.9 -2.2 -2.3
Arm fat percentage (left) 1.1 4.5 11.0 0.9 -1.8 -2.8 -3.3 -2.1 -2.7 -2.1 -2.9 -2.5 -2.4 -2.6 -2.5 -2.3 -1.5 -1.6 -2.5 -1.2 -2.0 -1.4 -1.6 -1.4 0.8 -2.6 -1.4 -2.0 -1.3 -1.7 -0.6 -1.8 2.9 -2.7 -2.1 -1.8 -2.3 -2.3
Average weekly red wine intake 1.2 1.7 4.8 0.0 -1.2 -0.6 -1.1 -0.9 -2.1 -1.3 -0.8 -1.4 -0.6 -1.0 -0.6 0.0 -1.2 -1.3 -1.2 -2.0 -2.1 0.3 -0.9 -1.0 2.0 -0.2 -1.1 -1.3 0.9 -0.8 -1.7 -1.8 1.1 -1.1 -1.5 -2.2 -2.0 -2.0
Handedness (chirality/laterality): Left-handed 2.0 2.4 7.1 0.4 -1.9 -2.4 -1.0 -1.9 0.9 -1.9 -1.6 -2.0 -1.8 -1.8 -2.0 -1.8 -2.0 -1.9 -1.7 0.2 -1.1 -1.8 -1.9 -2.7 -1.7 -1.9 -1.4 -1.7 -0.7 -0.5 -1.7 -1.4 -0.4 -1.0 -0.0 -1.1 -0.4 -0.5
Mood swings 0.9 1.7 11.5 -0.4 -1.1 -0.6 -0.5 -0.8 -2.9 -0.5 -0.7 -0.3 0.7 -0.1 0.3 1.2 -0.9 -0.6 -0.6 -0.6 -1.7 0.1 0.7 0.0 1.4 0.6 -3.4 -0.3 -1.1 -2.3 -1.9 -1.3 1.2 -0.4 -0.9 -1.7 -2.2 -2.2
Loneliness, isolation 2.0 2.8 6.2 0.5 -1.3 -1.8 -1.3 -1.9 -1.8 -2.0 -1.9 -1.3 -1.6 -1.6 -1.4 -1.2 -1.4 -1.0 -1.8 -1.6 -1.9 -1.3 -1.1 -1.2 1.5 -1.4 -2.5 -1.8 -2.2 -0.5 -1.1 -1.4 2.4 -2.1 -2.3 -1.6 -2.2 -2.1
Long-standing illness, disability or infirmity 2.6 4.0 10.5 1.3 -1.6 -1.7 -0.8 -2.6 -2.4 -2.1 -2.1 -1.2 -1.0 -1.4 -1.4 -0.4 -1.6 -1.2 -2.1 -2.2 -2.9 -1.5 -0.3 -1.4 1.8 -1.0 -3.1 -1.9 -1.5 -1.6 -2.5 -2.4 2.6 -1.7 -3.0 -2.8 -3.2 -3.2
Ever had bowel cancer screening 0.3 0.3 3.8 0.5 -0.2 1.0 -0.2 0.2 0.1 0.0 -0.3 -0.4 -0.2 -0.2 -0.5 -0.4 -0.1 -0.7 -0.4 0.1 0.2 -0.1 -0.4 -0.8 0.2 -0.5 -0.3 0.4 -2.0 1.8 0.5 -0.2 0.4 -0.4 0.3 0.1 -0.3 -0.3
Diabetes diagnosed by doctor 0.1 0.2 1.3 -0.4 -0.1 -0.2 -0.3 -0.2 -0.9 -0.5 -0.2 -0.4 -0.1 -0.6 -0.3 -0.3 0.2 0.5 -0.4 -0.9 -0.5 -0.0 -0.4 -0.5 0.3 -0.2 0.1 -0.4 0.4 -0.4 -0.3 -0.4 0.7 -0.4 -1.1 -0.5 -0.3 -0.3
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.6 4.1 1.0 0.2 0.0 -0.3 -0.3 -0.4 -0.3 -0.1 -0.1 0.1 0.1 0.2 0.3 0.0 -1.3 -0.0 1.3 -0.6 0.7 0.8 -0.6 2.0 0.2 -0.7 -1.1 0.0 -1.5 -1.1 -0.5 1.5 -0.6 -1.1 -0.7 -0.6 -0.7
Friendships satisfaction 0.5 0.7 5.1 0.1 -0.4 -0.9 -1.0 -1.1 -0.3 -0.7 -1.0 -0.6 -0.6 -0.6 -0.8 -0.9 -0.3 -0.2 -0.8 -2.3 -0.5 -1.4 -1.5 -0.4 -0.4 -0.9 -0.4 -0.3 -0.8 0.5 -0.2 -0.3 0.8 -0.9 -0.8 -0.3 -0.7 -0.7
Qualifications: nursing, teaching 0.4 0.6 2.9 -0.6 1.3 -0.0 0.7 0.1 1.2 1.0 0.3 0.9 0.8 0.8 0.7 0.7 1.6 -0.1 1.0 0.6 1.0 0.3 -0.2 0.3 -0.6 0.5 1.7 0.9 0.2 -0.2 0.5 1.2 0.1 0.5 -0.0 1.1 0.5 0.4
Commuting to job workplace: Walk 0.5 0.5 1.7 -0.4 -0.8 -1.1 -1.1 -0.9 -0.2 -0.4 -1.1 -0.6 -0.7 -0.6 -0.9 -0.7 -0.9 -0.4 -0.8 -1.3 -0.5 0.0 -0.8 -0.5 -1.2 -0.9 -0.1 -0.3 0.3 -0.9 0.3 -0.2 0.3 -0.8 -0.5 -0.3 -0.9 -0.9
Eye problems/disorders: Cataract 0.4 0.5 6.2 0.3 0.2 0.4 -0.5 -0.1 -1.0 -0.1 0.2 -0.0 0.2 -0.2 -0.1 0.2 -0.4 -0.6 -0.2 0.9 -0.3 -0.1 0.0 -0.7 1.0 0.2 -0.0 0.2 -2.0 2.5 -0.9 -0.6 0.1 0.0 -0.9 -0.7 -0.2 -0.2
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 2.7 1.6 -1.0 -1.2 0.2 -1.2 -1.2 -0.3 -0.6 -0.3 0.1 -0.1 -0.3 0.2 -1.4 -0.6 -0.6 -0.7 -0.8 -0.3 0.1 -0.8 0.1 -0.2 -1.4 -0.3 -0.8 -0.1 -1.2 -0.4 0.5 -0.4 -0.8 -0.6 -1.1 -1.1
Medication for cholesterol 0.7 1.1 4.2 -0.6 0.8 1.6 1.6 1.6 1.1 0.8 1.1 0.7 1.2 1.1 1.3 1.6 0.6 0.1 1.0 2.0 0.1 1.7 1.8 1.0 0.8 1.5 -0.5 0.3 0.4 -0.6 -0.4 0.0 -0.5 1.1 1.0 -0.1 0.2 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 0.9 3.1 -1.2 -0.0 0.3 0.6 0.3 1.0 0.8 0.3 -0.0 -0.0 -0.2 -0.2 -0.7 -0.3 1.8 0.3 1.0 1.2 0.8 -1.4 0.2 -1.5 -0.3 1.4 1.1 1.0 0.8 1.6 1.0 -0.7 0.6 0.8 1.1 1.5 1.5
Back pain experienced in last month 0.3 0.4 2.2 0.9 -0.5 -0.6 -0.2 -0.5 -1.0 -0.2 -1.0 -0.1 0.1 -0.3 -0.7 -0.3 -0.5 -0.3 -0.6 -1.5 -0.3 -0.4 -0.3 -0.2 -1.0 -0.7 -0.9 -0.2 -0.8 -1.2 0.2 0.0 0.3 -0.5 0.0 -0.0 -0.9 -0.9
Mineral and other dietary supplements 0.2 0.2 2.2 -1.3 -0.3 -0.6 0.1 -0.3 -0.0 -0.2 0.0 -0.2 0.1 -0.2 -0.0 -0.2 -0.2 -0.3 -0.1 1.5 -0.5 -0.3 0.1 -0.1 0.0 -0.2 -0.9 -0.3 0.2 -0.4 -1.2 -0.3 -0.0 -0.6 0.0 -0.4 -0.3 -0.2
Breast cancer (self-reported) 0.2 0.2 1.8 0.3 -0.2 0.1 -1.2 -0.3 -0.3 -0.3 -0.0 0.1 -0.3 0.0 0.0 -0.3 0.1 0.9 0.0 -0.1 -0.1 -0.0 -0.4 -0.0 0.9 -0.2 -0.3 -0.5 -1.3 0.3 0.4 0.2 0.5 -0.3 -0.5 0.3 -0.2 -0.1
Asthma (self-reported) 1.4 2.7 7.5 0.8 -1.5 -1.3 -1.4 -1.9 -0.7 -1.9 -2.0 -2.0 -1.9 -1.7 -2.1 -2.0 -2.0 -1.8 -2.0 0.4 -1.4 -2.0 -1.2 -2.7 -0.3 -2.1 -1.8 -1.8 -1.2 -0.9 -1.8 -1.6 1.2 -1.8 -1.3 -1.4 -1.3 -1.4
Osteoporosis (self-reported) 0.2 0.3 1.2 -0.0 -0.4 0.1 -0.8 -0.6 -0.7 -0.3 -0.2 0.0 -0.1 -0.2 0.1 0.1 0.3 -0.4 -0.4 -1.1 -0.4 -0.8 0.1 0.6 0.9 0.1 -1.0 -0.4 -0.9 -0.3 0.8 -0.3 1.0 -0.4 -0.5 -0.4 -0.5 -0.5
Osteoarthritis (self-reported) 0.3 0.4 2.4 0.6 0.1 -0.2 -0.2 -0.6 0.1 -0.5 -0.2 -0.4 0.1 -0.5 -0.3 -0.1 -0.5 -1.1 -0.4 -0.3 -0.8 -0.8 0.3 -0.3 0.6 -0.0 -0.7 -0.8 0.2 -1.4 -1.6 -0.8 0.8 -0.4 -0.8 -1.0 -0.5 -0.5
Medication: Aspirin 0.4 0.6 3.0 1.0 -0.1 -0.3 -1.5 -0.4 -1.7 -0.5 -0.6 -0.3 -0.7 -0.4 -0.3 -0.1 0.2 -0.1 -0.5 -1.4 -0.3 -0.4 -0.4 0.0 1.1 -0.3 -0.8 -0.1 -1.1 -0.3 0.8 -0.2 1.6 -0.3 -1.0 -0.3 -0.7 -0.7
Medication: Gliclazide 0.3 0.3 2.4 -0.7 -0.8 -0.0 -0.5 -0.7 -0.7 -0.5 -0.1 -0.2 -0.3 -0.7 -0.1 -0.3 -0.5 1.6 -0.3 0.0 -0.6 -0.2 -0.9 -0.6 0.3 -0.1 -0.8 -0.7 -0.2 -0.6 -0.2 -0.5 0.4 -0.3 -0.7 -0.5 -0.5 -0.4
Illnesses of father: None of the above (group 1) 0.4 0.4 1.1 -0.9 0.7 0.3 -0.1 0.9 0.6 0.6 0.6 0.6 0.3 0.7 0.5 0.3 0.6 0.3 0.7 1.0 0.9 0.4 -0.2 0.5 -0.7 0.5 1.0 0.5 0.5 0.6 0.6 0.6 -0.8 0.8 0.7 0.8 1.0 1.0
Smoking status: Current 0.3 0.4 3.0 1.0 -0.1 -0.8 -0.3 -0.6 -0.5 -0.2 0.1 0.0 0.1 0.0 0.1 0.5 -0.2 -0.0 -0.2 -1.0 -0.7 -0.4 -0.0 -0.7 0.6 0.4 -0.2 -0.5 1.1 -1.7 -1.4 -0.9 0.3 0.3 -0.2 -1.0 -0.5 -0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.0 2.1 6.1 -0.2 1.9 1.7 2.5 1.5 2.1 1.7 1.4 1.3 1.0 1.4 1.1 0.6 0.9 0.8 1.5 1.8 1.8 1.8 1.2 1.5 -0.7 0.9 1.9 1.4 1.2 0.1 1.0 1.6 -1.4 1.1 1.6 1.6 1.9 1.9
Whole body water mass 1.3 7.4 16.0 -0.1 -3.2 -4.0 -3.0 -3.2 -1.6 -3.0 -3.5 -3.4 -3.4 -3.4 -3.5 -3.6 -3.2 -1.9 -3.2 -1.6 -2.6 -2.6 -3.7 -2.2 -1.0 -3.8 -2.3 -2.9 -0.3 -1.6 -1.5 -1.9 1.7 -3.6 -1.8 -1.9 -2.3 -2.3
Leg predicted mass (right) 1.6 8.4 18.1 0.5 -3.1 -4.2 -3.3 -3.3 -1.7 -3.3 -3.8 -3.6 -3.8 -3.7 -3.8 -4.0 -3.1 -2.3 -3.5 -1.6 -2.7 -2.7 -3.8 -2.4 -0.7 -4.2 -2.1 -3.0 -0.5 -1.6 -1.6 -2.1 2.2 -4.0 -2.1 -2.0 -2.3 -2.3
Arm fat mass (left) 1.7 6.9 12.7 0.7 -2.7 -3.5 -3.6 -2.8 -3.1 -2.7 -3.5 -3.2 -3.1 -3.3 -3.2 -3.1 -2.4 -2.0 -3.2 -1.3 -2.5 -1.9 -2.5 -2.0 0.2 -3.4 -2.0 -2.7 -1.2 -2.0 -1.1 -2.3 2.8 -3.4 -2.2 -2.3 -2.6 -2.6
Number of self-reported non-cancer illnesses 0.4 0.7 4.7 1.1 -0.0 0.1 -0.0 -0.7 0.3 -0.8 -1.0 -0.5 -0.5 -0.7 -0.9 -0.7 -0.2 -0.4 -0.9 0.0 -0.7 -1.0 -0.0 -0.9 1.2 -0.8 -0.2 -0.8 -1.2 0.5 -0.1 -0.7 2.2 -0.9 -1.3 -0.6 -1.0 -1.0
Average weekly champagne plus white wine intake 1.3 1.7 5.3 0.1 -1.7 -2.0 -0.2 -1.2 0.0 -1.4 -1.3 -1.7 -1.2 -1.5 -1.3 -0.9 -1.5 -1.3 -1.7 0.3 -1.8 -2.3 -1.1 -1.2 -0.6 -0.9 -0.9 -1.0 1.6 -0.7 -1.2 -2.2 0.0 -0.9 -0.4 -2.1 -1.2 -1.2
Miserableness 1.0 1.8 9.7 -0.0 -1.4 -1.4 -1.0 -0.6 -2.1 -1.0 -1.7 -0.9 -0.2 -0.7 -0.8 -0.3 -0.9 -1.4 -1.2 -1.3 -1.5 -0.1 -0.6 -0.7 -0.0 -0.9 -2.6 -1.1 -0.6 -3.1 -1.1 -0.8 1.5 -1.7 -1.0 -0.9 -2.2 -2.2
Guilty feelings 0.9 1.4 4.4 0.3 -1.0 -1.5 -0.0 -1.6 -1.0 -1.1 -1.6 -0.8 -0.6 -1.1 -1.1 -0.7 -1.3 -0.8 -1.2 -2.1 -1.3 -1.7 -0.8 -1.5 -0.1 -1.0 -1.5 -1.5 0.1 -0.9 -1.5 -0.7 1.4 -1.2 -1.2 -1.0 -1.4 -1.5
Wears glasses or contact lenses 1.0 1.1 4.9 2.0 -0.4 -0.6 -1.7 -1.1 -1.0 -0.9 -1.2 -0.7 -1.0 -1.2 -1.0 -1.1 -0.6 -0.3 -1.0 -1.1 -0.7 -0.7 -1.0 -0.9 1.1 -1.2 -0.2 -0.6 -1.2 0.0 0.0 -0.4 2.2 -1.4 -1.9 -0.6 -0.9 -1.0
Ever taken oral contraceptive pill 0.1 0.1 0.7 -0.5 0.3 0.2 0.1 -0.0 0.5 0.4 0.1 0.3 0.4 0.4 0.5 0.7 -0.3 -0.3 0.3 0.5 -0.2 0.1 -0.1 0.5 -0.2 0.4 -0.2 0.6 -0.3 0.8 -0.5 0.1 0.1 -0.1 0.0 -0.1 -0.5 -0.5
Hearing aid user 0.2 0.2 0.7 -0.8 0.3 -0.6 0.5 0.2 0.0 0.5 0.0 -0.3 -0.3 0.5 -0.0 -0.0 0.1 -0.2 0.1 0.3 0.5 -0.3 -0.0 0.7 -0.8 -0.1 0.8 0.6 0.4 0.5 0.7 0.3 -0.8 0.2 0.6 0.4 0.5 0.5
Mother’s age at death 2.9 3.7 9.6 0.9 -2.3 -1.4 -1.9 -1.7 -1.8 -1.9 -2.3 -2.3 -2.1 -2.2 -2.2 -2.0 -1.7 -1.1 -2.3 -3.1 -2.1 -1.4 -1.5 -1.9 -0.2 -2.1 -1.9 -1.7 -2.1 0.5 -1.4 -2.0 1.8 -2.3 -1.9 -2.1 -2.2 -2.2
Financial situation satisfaction 0.3 0.3 1.9 0.8 -0.2 -0.9 -0.4 0.0 -0.0 -0.5 -0.5 -0.5 -0.3 -0.2 -0.3 -0.2 -0.2 -0.9 -0.3 -0.3 -0.4 -0.6 0.8 -0.0 0.0 -0.5 -0.6 -0.5 -1.4 1.2 -0.6 -0.2 0.3 -0.5 -0.7 -0.3 -0.5 -0.5
Tinnitus: Yes, now most or all of the time 0.4 0.5 3.8 -1.7 -0.3 -0.2 1.0 0.2 -0.7 0.8 0.2 0.1 0.2 0.4 -0.0 -0.1 -0.6 0.0 0.1 -0.5 0.5 0.8 0.2 0.5 -2.0 0.1 0.1 0.8 -0.2 0.6 0.5 0.1 -1.3 0.2 1.1 0.2 0.5 0.5
Commuting to job workplace: Public transport 2.2 2.6 7.5 0.5 -1.9 -2.1 -1.6 -2.7 -0.6 -2.1 -1.4 -1.6 -2.4 -1.9 -1.9 -2.5 -0.8 0.5 -1.7 -1.2 -1.1 -1.7 -2.7 -2.5 -0.2 -2.1 -0.8 -2.2 -0.9 -0.2 -0.5 -1.1 1.0 -1.8 -1.6 -0.8 -0.6 -0.5
Eye problems/disorders: Glaucoma 0.7 0.8 3.6 0.8 -0.8 -1.0 -0.9 -0.7 -1.1 -1.1 -0.6 -1.5 -0.8 -1.0 -1.0 -1.0 -0.9 -1.4 -1.0 -0.1 -0.7 -0.0 -0.7 -1.9 -0.4 -0.9 -0.7 -0.8 -0.5 0.8 -1.1 -1.1 0.2 -0.6 -0.6 -1.0 -0.2 -0.2
Medication: Blood pressure 0.3 0.5 3.8 0.7 1.0 0.5 -0.3 0.0 -0.9 0.5 0.7 0.8 0.6 0.7 0.8 0.5 0.7 0.0 0.7 -0.9 0.7 0.3 -0.1 -0.0 1.0 0.6 0.9 0.9 -0.6 2.0 0.7 0.7 0.5 0.4 -0.5 0.6 0.5 0.6
Pain type(s) experienced in last month: Hip pain 0.4 0.5 3.7 0.3 0.5 0.0 0.6 -0.2 -1.1 0.1 -0.2 0.4 0.1 0.2 0.1 0.2 0.8 0.2 0.2 -1.2 0.1 -0.0 0.3 0.5 1.1 -0.1 0.3 -0.1 -1.9 0.5 0.6 0.6 1.5 -0.3 -1.4 0.3 -0.6 -0.6
Supplements: Fish oil (including cod liver oil) 0.3 0.5 1.6 1.3 0.6 0.9 0.0 0.5 0.1 0.5 0.3 0.7 0.4 0.8 0.4 0.6 0.4 0.7 0.5 -1.2 0.8 0.3 0.4 0.5 0.3 0.5 1.0 0.8 -0.8 1.1 1.1 0.8 -0.1 0.7 -0.1 0.9 0.4 0.3
High cholesterol (Self-reported) 0.3 0.6 2.5 -0.6 1.1 0.9 0.4 0.9 0.4 1.0 0.7 0.9 0.9 0.7 0.7 0.6 0.7 0.6 0.7 -0.0 0.8 0.7 0.3 1.3 -0.3 0.7 1.1 1.6 0.6 0.7 0.8 0.8 -0.3 0.8 0.6 0.8 0.7 0.7
Medication: Bendroflumethiazide 0.2 0.3 3.3 1.3 0.7 0.3 -1.2 -0.0 -0.6 0.1 0.2 0.4 0.5 0.3 0.3 0.4 0.2 0.4 0.3 -1.8 -0.0 0.4 -0.2 -0.5 1.1 0.4 0.4 -0.0 0.2 0.4 -0.6 -0.1 0.5 0.4 -0.3 -0.1 0.0 -0.0
Medication: Paracetamol 0.2 0.3 1.1 0.4 0.2 0.5 0.4 0.2 -1.1 0.8 0.5 0.6 0.8 0.6 0.6 0.6 -0.6 -0.0 0.4 -0.4 0.6 0.7 0.4 0.2 -0.6 0.7 -0.1 0.6 -0.5 0.9 0.7 0.8 0.0 0.5 0.0 0.4 0.5 0.5
Medication: Lisinopril 0.2 0.3 1.0 0.2 -0.1 0.4 -0.9 0.2 -1.0 0.1 0.4 0.2 0.6 0.4 0.5 0.7 -0.3 0.6 0.3 0.4 -0.1 0.5 0.3 -0.9 0.8 0.7 -0.9 0.2 -0.3 -0.9 -0.7 -0.3 0.2 0.4 -0.3 -0.3 -0.3 -0.2
Medication: Atorvastatin 1.0 1.2 7.0 -0.3 1.1 1.2 -0.1 1.1 0.3 1.0 0.5 1.3 0.7 1.1 0.8 0.7 1.7 0.3 1.0 -0.4 1.3 0.6 -0.2 1.5 -0.8 0.5 1.6 1.4 -0.7 2.6 1.7 1.6 -0.2 0.7 0.6 1.7 0.7 0.7
Illnesses of father: High blood pressure 2.9 3.6 9.4 -0.9 1.6 2.3 3.1 2.3 1.3 2.1 1.4 2.4 2.0 2.2 2.0 2.0 1.8 2.3 2.1 -0.1 1.9 2.0 1.5 3.0 -0.2 1.8 1.1 2.1 1.0 -0.2 2.8 2.5 -0.9 1.8 2.0 2.4 1.0 1.0
Alcohol drinker status: Never 0.7 0.8 3.2 1.8 -0.4 -0.3 -0.6 -0.6 -0.8 -0.9 -0.1 -0.1 0.2 -0.2 0.2 0.9 0.2 -0.5 -0.5 -1.0 -1.5 -0.5 0.6 -0.5 0.9 0.7 -1.1 -0.7 -0.7 0.0 -1.5 -1.6 0.3 -0.0 -1.2 -1.8 -1.4 -1.3
Ever smoked 1.0 1.8 7.9 0.7 -1.1 -2.2 -1.4 -1.1 -0.6 -1.4 -1.6 -1.6 -0.9 -1.2 -1.5 -0.8 -0.8 -2.8 -1.6 -0.1 -1.6 -1.3 -0.8 -2.2 0.3 -1.2 -1.0 -1.4 -0.2 -1.0 -1.5 -1.9 0.6 -1.1 -0.3 -1.9 -1.3 -1.4
Basal metabolic rate 1.5 8.4 17.6 0.1 -3.3 -4.2 -3.2 -3.3 -1.9 -3.2 -3.8 -3.6 -3.6 -3.6 -3.8 -3.9 -3.3 -2.1 -3.5 -1.7 -2.8 -2.7 -3.8 -2.4 -1.0 -4.1 -2.4 -3.1 -0.5 -1.8 -1.6 -2.1 2.0 -3.9 -2.0 -2.1 -2.5 -2.5
Leg fat percentage (left) 0.8 2.8 7.4 0.5 -1.3 -2.1 -2.3 -1.3 -2.7 -1.5 -2.1 -1.9 -1.5 -1.9 -1.6 -1.3 -0.9 -1.5 -1.9 -0.7 -1.9 -0.7 -0.5 -0.6 1.5 -1.5 -1.5 -1.9 -0.1 -2.3 -0.8 -1.9 2.4 -2.0 -1.4 -2.0 -2.0 -2.1
Arm fat-free mass (left) 1.3 6.6 12.8 0.0 -3.1 -3.6 -2.7 -2.9 -1.8 -2.9 -3.1 -3.2 -3.0 -3.1 -3.1 -3.2 -3.2 -2.0 -3.0 -1.3 -2.6 -2.3 -3.1 -2.3 -0.8 -3.3 -2.7 -3.0 -0.2 -1.9 -1.7 -2.1 1.6 -3.4 -1.6 -2.1 -2.1 -2.2
Number of operations (self-reported) 0.7 1.0 4.2 0.6 -0.5 -0.9 0.0 -0.7 0.2 -1.1 -1.0 -1.0 -1.1 -1.1 -1.0 -1.0 -0.3 -1.7 -1.0 0.0 -0.7 -0.3 -0.7 -1.2 0.7 -1.4 -0.4 -1.2 -2.1 1.3 -0.5 -0.3 1.5 -1.4 -1.8 -0.3 -0.9 -0.9
Average weekly beer plus cider intake 1.8 2.6 6.5 -0.5 2.0 1.2 2.2 2.2 1.9 1.5 1.5 1.1 0.9 1.1 1.0 0.6 1.6 0.7 1.7 1.2 2.3 1.8 1.0 1.1 -1.4 0.7 2.5 1.7 1.0 1.3 1.4 2.0 -1.6 1.7 1.5 2.1 2.5 2.5
Irritability 0.7 1.2 10.0 -0.8 -0.9 -1.1 1.0 -0.5 -2.2 -0.0 -0.3 0.1 1.0 0.1 0.4 1.2 -0.8 0.3 -0.2 -0.9 -1.0 0.1 0.8 0.3 -0.5 0.8 -2.4 -0.2 1.4 -3.2 -1.4 -0.7 -0.6 0.5 0.4 -1.0 -1.1 -1.1
Risk taking 0.8 1.2 4.8 -0.0 -1.2 -1.0 0.1 -1.2 -1.2 -1.0 -1.3 -1.4 -1.6 -1.4 -1.3 -1.2 -0.7 -0.0 -1.2 -1.5 -0.8 -1.4 -2.2 -1.1 0.2 -1.3 -1.2 -1.2 -0.4 -1.5 -0.4 -0.7 0.7 -0.9 -0.8 -0.8 -1.0 -0.9
Ever had prostate specific antigen (PSA) test 1.4 1.7 5.5 1.3 -1.7 -1.7 -1.2 -2.3 -1.5 -0.9 -1.7 -0.7 -1.3 -1.2 -1.3 -1.0 -1.6 -0.8 -1.4 -1.6 -1.3 0.0 -1.2 -1.4 0.3 -1.3 -0.8 -0.7 -0.9 -0.7 -0.4 -0.8 1.4 -1.6 -1.5 -1.0 -1.8 -1.8
Fractured/broken bones in last 5 years 0.6 0.8 4.2 -0.3 -0.6 -0.9 -0.4 -0.6 -1.8 -0.8 -1.0 -0.5 -0.4 -0.8 -0.9 -0.5 -0.3 -2.0 -1.0 0.1 -0.9 -0.9 -0.5 -1.1 0.8 -0.8 -0.9 -0.9 0.6 -1.0 -1.2 -1.0 1.2 -0.7 -0.3 -0.9 -0.8 -0.8
Age started oral contraceptive pill 0.5 0.6 2.9 0.1 0.5 0.6 -0.4 0.7 -0.1 0.4 0.9 0.1 0.3 0.4 0.3 -0.2 -0.2 1.7 0.6 0.7 0.9 0.4 0.5 -0.1 -1.0 0.3 0.1 1.0 0.2 0.5 0.2 0.6 -1.3 1.0 1.1 0.7 1.6 1.6
Diastolic blood pressure, automated reading 0.1 0.4 3.0 1.0 0.2 -1.1 -0.2 -0.4 -0.7 -0.4 -0.7 -0.8 -0.3 -0.6 -0.6 -0.2 -0.6 -1.2 -0.5 -0.3 -0.4 -0.8 0.2 -0.1 0.0 -0.3 0.0 -0.4 0.9 -1.7 -0.6 -0.6 0.1 0.0 -0.3 -0.9 -0.2 -0.3
Ever depressed for a whole week 0.6 0.7 2.5 -0.7 1.0 0.7 1.4 1.0 -0.3 0.8 0.8 0.4 1.0 0.8 0.8 0.6 1.6 1.2 0.9 -0.2 0.8 1.3 0.1 1.0 0.6 0.7 0.6 1.1 0.6 -0.2 1.1 0.6 -0.1 1.0 0.9 0.7 0.8 0.8
Unable to work because of sickness or disability 1.9 2.5 6.8 0.7 -1.2 -1.7 -1.1 -1.5 -2.6 -1.7 -1.6 -1.5 -1.2 -1.2 -1.2 -0.7 -0.6 -1.7 -1.7 -2.5 -1.9 -2.1 -2.0 -1.9 0.4 -0.9 -1.4 -1.5 -0.3 -0.4 -1.5 -2.0 2.0 -1.4 -2.2 -2.1 -1.8 -1.8
Commuting to job workplace: Cycle 0.4 0.5 3.2 -0.0 -1.2 -0.8 0.1 -0.4 -0.4 -0.0 -0.5 -0.2 0.1 0.2 -0.2 -0.1 -0.6 0.7 -0.2 -1.8 -0.4 -0.0 -0.0 -0.1 -1.3 -0.3 -1.6 -0.3 0.2 -1.7 -0.1 0.4 -0.7 -0.3 0.5 0.3 -0.5 -0.5
Myopia 1.7 2.5 7.8 -1.3 1.0 1.2 2.0 1.8 2.3 1.6 1.2 1.7 1.3 1.7 1.5 1.7 2.5 -0.2 1.4 0.7 1.7 1.7 1.5 2.0 -1.4 1.4 1.6 2.0 0.2 1.3 2.8 1.9 -0.9 1.5 0.8 1.6 1.1 1.0
Vascular/heart problems diagnosed by doctor 0.2 0.5 1.5 -1.0 -1.2 -0.5 -0.2 -0.6 0.3 -0.8 -0.0 -1.0 -0.9 -0.7 -0.7 -0.7 -0.7 -0.3 -0.8 0.8 -0.7 -0.4 -0.7 -1.1 -0.8 -0.5 -0.6 -1.0 0.9 -0.7 -0.9 -1.0 -1.2 -0.2 0.3 -0.9 0.1 0.1
Cholesterol lowering medication 0.2 0.3 2.3 0.1 0.7 0.0 -0.7 -0.4 -0.4 0.2 0.2 0.0 0.2 -0.2 -0.3 -0.6 -0.1 0.6 0.2 0.2 0.5 0.4 -0.8 -0.3 -0.3 -0.2 1.5 0.7 0.3 1.1 -0.1 0.2 -0.1 0.2 0.0 0.4 0.8 0.8
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 1.9 0.6 1.0 0.5 0.4 0.8 -0.3 0.4 0.2 0.2 0.3 0.4 0.3 0.3 0.8 0.1 0.5 -0.4 0.3 1.0 0.3 1.4 0.8 0.2 0.7 0.1 -0.4 0.3 0.3 0.5 0.5 0.1 -0.3 0.4 0.1 0.0
Pain experienced in last month 0.2 0.3 0.9 -0.5 -0.4 -0.3 -0.6 -0.6 -0.5 -0.3 -0.4 -0.4 -0.7 -0.6 -0.4 -0.4 -0.5 0.5 -0.5 0.0 -0.7 -0.4 -0.4 -0.2 0.9 -0.3 0.0 -0.3 -0.3 0.9 -0.6 -0.9 0.4 -0.5 -0.3 -0.8 -0.6 -0.5
Supplements: Calcium 0.7 0.8 2.5 -0.3 0.2 0.7 0.6 0.8 -0.8 0.6 1.0 0.8 0.4 0.8 1.0 1.1 0.8 1.4 0.8 -1.6 0.5 1.3 0.5 1.4 -0.4 1.2 -0.3 1.1 0.7 -0.6 1.6 0.3 -0.8 1.3 1.0 0.1 0.5 0.6
Basal cell carcinoma (self-reported) 0.8 1.0 5.9 -1.5 0.0 0.5 0.3 0.8 0.4 1.1 0.9 0.6 0.5 0.7 0.8 0.8 -0.0 1.3 0.8 -0.5 0.8 0.5 0.7 1.4 -1.6 1.0 0.6 1.2 1.5 -0.2 0.3 0.6 -2.4 1.3 1.5 0.5 1.1 1.1
Heart attack/myocardial infarction (self-reported) 0.4 0.6 2.7 1.6 0.7 -0.6 -0.7 -0.3 0.9 -0.3 -0.6 0.4 0.1 0.2 -0.1 0.1 1.0 -0.4 -0.1 -0.5 -0.0 -0.9 0.4 -0.1 1.4 -0.3 0.8 -0.1 -1.7 1.3 0.4 0.3 1.3 -0.4 -1.2 0.4 -0.6 -0.6
Deep venous thrombosis (DVT) (self-reported) 0.2 0.3 1.6 -0.9 -0.3 -0.5 0.0 -0.5 0.2 -0.4 0.3 0.0 -0.4 -0.2 0.1 0.1 -0.6 -0.9 -0.1 1.2 -0.3 0.3 0.5 -0.8 -0.5 0.1 -1.0 -0.3 0.7 -0.6 -1.2 -0.4 -0.0 0.1 -0.1 -0.4 0.2 0.2
Heart disease (siblings) 0.9 1.1 4.3 0.4 1.2 0.5 1.4 1.3 -0.2 0.5 0.4 1.4 1.5 1.3 1.4 2.0 2.1 -0.8 0.9 0.7 0.1 1.5 1.8 1.5 1.5 1.3 0.4 0.4 0.3 -0.2 0.8 0.8 0.8 0.5 -0.7 0.5 -0.7 -0.8
Alcohol drinker status: Previous 0.3 0.4 1.6 -1.0 0.3 0.3 0.7 -0.2 -0.5 0.7 0.6 0.6 0.3 0.8 0.5 0.3 0.1 0.6 0.8 0.0 0.8 0.6 0.3 0.9 -0.4 0.3 0.5 0.1 -1.2 0.3 0.3 0.9 -0.8 0.3 0.5 0.9 0.6 0.6
Pack years of smoking 3.5 5.2 11.2 0.3 -2.4 -2.7 -2.4 -2.8 -1.4 -2.7 -2.2 -2.5 -2.5 -2.5 -2.2 -1.8 -2.5 -0.5 -2.5 -1.9 -2.9 -3.4 -2.1 -1.9 1.2 -1.7 -2.3 -2.7 -0.4 -2.0 -2.8 -3.3 1.2 -1.9 -2.3 -3.2 -2.2 -2.2
Impedance of whole body 0.3 1.6 3.7 0.2 1.3 1.5 0.7 1.6 0.8 1.4 1.3 1.2 1.0 1.4 1.0 1.1 1.1 -0.4 1.2 0.7 1.8 1.2 1.2 0.2 -1.1 1.3 1.7 1.6 -0.8 1.8 0.5 0.8 -1.7 1.9 1.4 1.0 1.8 1.8
Leg fat mass (left) 1.0 4.0 8.0 0.5 -1.7 -2.7 -2.8 -1.7 -2.4 -2.0 -2.8 -2.5 -2.3 -2.5 -2.4 -2.3 -1.5 -1.7 -2.4 -0.9 -2.0 -1.3 -1.6 -1.0 0.7 -2.5 -1.5 -2.2 -0.5 -2.1 -0.7 -1.8 2.5 -2.6 -1.5 -1.8 -2.1 -2.1
Arm predicted mass (left) 1.0 5.3 11.5 -0.4 -2.9 -3.4 -2.4 -2.6 -1.7 -2.5 -2.8 -2.9 -2.7 -2.8 -2.8 -3.0 -3.0 -1.6 -2.7 -1.0 -2.4 -2.1 -2.8 -1.9 -0.9 -3.0 -2.6 -2.7 -0.2 -1.8 -1.4 -1.8 1.3 -3.1 -1.2 -1.8 -1.9 -2.0