Best TWAS P=8.55e-09 · Best GWAS P=1.25e-08 conditioned to 0.102
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | CCNO | 0.13 | 0.14 | lasso | 10 | 0.14 | 1.8e-17 | -5.1 | 5.4 | 5.9e-08 | -0.94 | 0.08 | 0.91 | FALSE |
| 2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | CCNO | 0.06 | 0.03 | blup | 45 | 0.03 | 1.6e-02 | -5.6 | 5.4 | 6.4e-08 | -0.92 | 0.02 | 0.89 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CCNO | 0.09 | 0.06 | blup | 45 | 0.07 | 1.5e-07 | -5.0 | 5.8 | 8.6e-09 | -0.83 | 0.11 | 0.89 | TRUE |